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  1. Hi all, and thank you for this site. After multiple attempts to taper over the last 5/6 years, some medically supervised, some not, I came off citalopram 10mg at the end of June this year with the intention of pushing through withdrawal come what may. I had been on 20mg until earlier this year and decreased straight to 10mg which I’d been on for about three months. Needless to say now I am now not having fun at all and am considering reinstating. My intention was to replace the SSRI with 5htp which I’ve been taking for a week at 50mg then 100mg. I still have some citalopram tablets left (I’ve asked my husband to hide them) so am wondering if I should crush them and weigh them or just go straight to the liquid version and do it that way. I have a history of depression and anxiety, but at the moment am in a mental state I do not recognise, it’s utterly bleak and strange, like everything around me looks the same but I am a stranger to myself and my surroundings. I’m not sure I can do this long term. I’m not suicidal but have had fleeting very dark thoughts. Thank you in advance for any advice/thoughts. X
  2. Hi, decided to share my experience with 5-HTP. In brief, I started taking it in February this year, hoping it would help my depression and anxiety. I took it in doses of 100-200 mg per day (one dose in the morning and sometimes another before sleep) and indeed noticed some mood improvements. However, roughly a month in, I took a dose of approximately 150 mg and another similar dose later the same day. Very soon after this, I noticed an almost total loss of genital sensitivity, developing also anorgasmia and watery ejaculate. At this point, I stopped the 5-HTP immediately. Now, approximately 4 months after this, the anorgasmia has lifted completely. The numbness persists but is not as severe/complete as in the beginning. At times, there have been quite sudden improvements but then it seems to worsen somewhat again, making me question if I was just imagining the improvement. I can't believe I was naive enough to take the 5-HTP just because it appeared to be a seemingly harmless "natural supplement" despite being serotonergic. My only consolation is that "thanks" to this, I dodged the bullet of starting on escitalopram (I was a day away from it). Furthermore, I have taken one or two doses of low-dose (about 5 mg) mirtazapine and doxepin for sleep a few years ago – didn't get any problems from them.
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