Jump to content

Search the Community

Showing results for tags 'antidepressants'.



More search options

  • Search By Tags

    Type tags separated by commas.
  • Search By Author

Content Type


Forums

  • Support
    • Read This First
    • Introductions and updates
    • Tapering
    • Symptoms and self-care
    • Finding meaning
    • Relationships
  • The commons
  • Current events
    • Events, controversies, actions
    • In the media
    • Success stories: Recovery from withdrawal
    • From journals and scientific sources

Found 36 results

  1. Hi, where do I start? I am in desperate need of help with tapering my Mom off of a variety of meds. So here is our story... We are originally from London, we now live in South Africa. I mam 46 and Mom is 66, I have a son who is 14 and we now share a rented house. My Dad died March 2016. This caused huge emotional trauma for my Mom as you can imagine. My Gran in the UK then became sick so Mom flew over to help (not ideal when you are going through grief and already not coping on a day to day basis, her world had been crushed in one night) So, she went to the UK and it was hard to cope with my Gran being so ill, my Mom had a breakdown, she ended up in a Psychiatric unit (admitted herself) after becoming addicted to Alzam (benzo). She originally was prescribed these here in SA years ago to manage anxiety and panic attacks. Once the emotional stress hit she started taking them more and more each day until she tried to stop, cut them down on her own and that is when the trouble and side effects started. She then went into the Psych unit in the UK. They then put her on to another type of benzo Diazepam, Olanzapine, Mirtazpine and she is also on heart and blood thinners. Once she came out she was not much better, I managed to get her on a flight and back to SA. 2 month later she just got worse, the local Dr and team tried to taper her off of the Diazepam but she is not good with the withdrawal symptoms. After many Drs, therapists, advice, research and suffering alot at home (for all of us) I checked her into a very expensive rehab here. 28 day program. She is now on: Circadin, Trepiline, Rivotril, Solian and heart and blood thinners. The program did not work, the rehab and getting her off the benzos and antipsychotics did not work. What I need advice, help with from anyone is what now? The cost of the rehab was thousands.... Her current state is anxiety all the time, her eyes are large and she looks constantly in fear or amazement, delayed speech, confusion, short term memory is bad, long term not great either, no energy, out of breath, so her quality of life is dismal. She does not go out and has a 'cannot be bothered attitude towards much of life, she lost 17 kg and looks anorexic, she eats but does not put on weight. I would love to look at tapering but just do not know which one to start with? How much and obviously with her it would need to be slow. Can one start to reduce the antipsychotic first? I know Benzos are highly addictive and Rivotril is one! Can anyone help?
  2. Is there hope?

    Hello all, Thank you for taking the time to read my post. I don't know if there is any hope left for me and my ex-boyfriend. We were together for three years, and we went through a lot of good and bad things of course. We were also doing a LDR, and as such it was hard to see each other often. But when we did see each other, it was the most amazing times. My ex used to be so full of love, care, empathy, kindness and reason. He was diagnosed with some form of depression, and then he started to take the pills (sorry I don't remember which). Shortly after he began taking them, we actually broke up over some stupid things we would usually just work over. Now, he has changed into a completely different person. He is cold, hostile, and really short with me. I understand that I am his ex, but he wouldn't treat me that way ever before. He told me he stops caring about everything, including me. Then he began to blame me for everything and he said he has regret and resentment for me. I believe the doctor was lowering the doses gradually, I believe halving it each week. Then yesterday he said that he was completely off of it. And I am not sure if he will return back to the same person he once was? He was having many severe mood swings, but one thing always was clear was that he didn't want to be with me at that moment. He says he missed me physically, but not emotionally. I am not sure what to think about that. Then he keeps wanting to cut off contact with me, I believe the only reason why he's let me text him is because I beg him to let me know updates about his mental health. The antidepressants definitely ruined our relationship. And I am wondering once he is off... Will he return back to the same person he once was before taking them? It appears that he has lost his attachments to me, our amazing memories and it kills me.
  3. Hey everyone, My name is Abby and I have been off Prozac for 3.5 months now. I'm currently experiencing intense withdrawal and the return of mental states I never thought I'd have to experience again, and I would really like to connect with others who are going through similar during this long, difficult process. Background info: I always had tendencies towards anxiety, depression and obsessive compulsive disorder (the Pure-Obsessional variety) since childhood. At 16 these symptoms very rapidly became so severe my whole life fell apart within a matter of days (Going on the contraceptive pill at this time may have been a contributing factor). I didn't have a full breakdown until I was 18, at which point I was taken to the doctor, put on Sertraline, and referred to psychiatry. The following 8 years consisted of several psychiatric admissions, different drugs including clomipramine, seroquel, mirtazipine, prozac, and possibly a few others for shorter periods. I lost pretty much everything, my obsessional fears were so strong that I attempted suicide more than once, developed a bad cocaine/mephadrone habit, was a constant worry to my family. There were times, however, where the medication would help a lot. At 60mg of Prozac I went through some periods of being functional - I went to work, got into a relationship etc. These were a great relief but I can't say I was truly happy as the fears were never properly dealt with. My last hospital admission was in 2014 when I was 24. I had attempted to come off medication as I believed I had to deal with the underlying problems, and I hated the weight gain side effects. Looking back, this was doomed to fail as I was still using cocaine regularly, drinking a lot, and didn't have any proper support mechanisms in place. I was fine for 6 months then crashed, was borderline psychotic with the OCD symptoms, depressed and anxious beyond belief and desperately wanted to die (and believed I deserved to). I was in a psych ward for just over 2 months before new meds kicked in - clompipramine and (randomly, I don't know why) Epilum, as I was told it 'balanced moods'. A year later I went back on to old faithful Prozac and also came off the contraceptive pill. I had always been told the same about it, that it leveled out moods, and don;t think it's a coincidence that my symptoms became much more manageable a few months after stopping it. I then managed to stay at 40mg for 2 years and my life changed drastically for the better. to myself and everyone around me it was like a miraculous recovery - I stopped taking drugs, began volunteering at a Buddhist meditation centre, got my dream job, published a novel, did newspaper interviews about my experiences, ...I pretty much had my dream life. It was like being reborn after thinking everything was all over...forever. It was in January 2017 that I decided to gradually wean off Prozac. Over the following 10 months I reduced until stopping completely in October. In these past 2 years I have done extensive mind training and spiritual exploration, which has probably been the main factor in this recovery. My life is pretty much dedicated to this practice now - I still volunteer at the meditation centre, go on meditation retreats throughout the year, and have also completed a Reiki Mastership. It was always potentially on the cards after exploring my mind with psychedelic drugs in the past, doing past life regressions and also taking Ayahuasca twice in ceremonies. It was around the time of the reiki mastership that I was weaning off the last of the Prozac. Things became challenging - but at first I welcomed it. I was in a strong place mentally, and my mental health hadn't plagued me intensely for a few years. I was made aware that the Reiki energy can churn things up to be healed, but I think that the combination of this, a massive flare up of a back issue that left me not able to walk for weeks, family pressures and intensive mind exploration during retreat that has led me to my current situation. Since December just passed things have been incredibly difficult. I have experienced a return of old OCD obsessions, to the point where I've had panic attacks for days that made my vision blur, heavy depression, crying all the time, existential fears and experiences which medically would look similar to psychosis (although I believe that term can pathologize important and natural inner processes), identity confusion etc. I knew it would be hard, I just never expected to feel this level of horror ever again. Having said that, I know things are different this time round - I have a level of insight gained through spiritual practice that is keeping me going. Energetically, I'm aware that I am creating this reality on various levels, and that I need to relax as much as possible to allow it to pass through the way it's supposed to. I'm no stranger to facing the darkest parts of the psyche, but it's still terrifying and I'm struggling to cope day to day. To make matters worse, my Mum has gone abroad for cancer treatment and I'm now caring for my little brother and sister 4 days a week which is incredibly stressful (I'm used to having my own space and being able to retreat when I need to). My CBT therapist has discharged me as she feels I cannot engage with therapy under this amount of stress, but encouraged me to come back when my Mum gets back. To be fair, she never taught me anything I didn't naturally learn in meditation and I was only seeing her regularly to comply with services. I have however started going for reiki treatments with the person who facilitated the course I was on last year - he is exceptionally intuitive, knowledgeable and takes an all round, individual approach. One session with him last week was worth a year of 'traditional' therapy. So I'm hoping that continuing with this will help. Anyway, sorry for the essay. I don't have many people to talk to about all this. It's also weird for me to ask for help now as I haven't needed it in so long - I'm usually now the one that helps everyone else. It's a scary and heartbreaking thing to go back to a place you thought you'd left long in the past, but I do believe deep down that I have done so in order to face my demons fully and emerge stronger in the long run. Thank you if you made it this far, I'm looking forward to connecting with others on this site. You are all incredibly strong to be doing what you're doing, no matter what stage you're at. Much love x
  4. I apologize in advance for the topic. It is like beating a dead horse discussing this, I swear. Was getting pretty upset this morning going through the comments section of a video on youtube discussing the common side effects associated with antidepressants. So many people on there singing the praises of these drugs. Crediting them with saving their lives. I have several family members that still, even after witnessing what I went through (which would have scared me into questioning the legitimacy of psychiatric claims if I had been on the outside looking in) still insist that they have a "condition" that requires drugs to treat. The comments section was filled with people saying that claims of antidepressants causing an increase in violent behavior is pseudoscience, and that the drugs help far more often than they harm. The only way to see is to know, evidently. Shames me to think that I used to be one of them. Ignorant and hopeful. Wouldn't be on this site today if not for my trusting of these drugs and those that prescribed them to me. I know I can do nothing. I realize that it is a complete waste of my time and energy to become upset over something that I will never have any influence over. Still, I am filled with rage thinking of everyone on here, everyone around the world that has had their life stolen in one way or another thanks to this aggressive and lethal "answer" to emotional upsets. Our stories will be buried somewhat in the void of disbelief. We are thought of as crazy, our experiences as anomalies, or as merely craving attention and lying for the sake of it. I feel defeated, and somewhat alone.
  5. A live interview last night about PSSD awareness on Juliemadblogger Radio. It has been recorded and widely available for free on demand at http://www.blogtalkradio.com/juliemadblogger/2017/10/22/guest-from-uk-pssd-sexual-dysfunction-from-psychiatric-drugs You can also download the mp3 version that can be listened to offline by clicking the download icon at the top too... (top right) Please share and distribute as widely as possible on social media and websites. And help spread PSSD Awareness.
  6. I am at such a low point because of my moms obsession with me taking medication. Any time I get remotely upset about anything she immediately asks if I'm "taking my meds". Her harassment is what's pushing me in to depression and no amount of words make her understand what a piece of garbage she makes me feel when she consistently invalidates me. I can never be anything but happy or I'm crazy to her.
  7. I'm a 28 year old man from Greece. I am suffering from ssri side effects 8 years now. I think that Imight suffering from withdrawal symptom (or Pssd). I don't know also if there is a difference. I was diagnosed with OCD in 2009 and I was on Prozac from 2009 to 2014 daily on 60mg. On this time interval I have noticed that I had weak erections without paying real attention. But when I I had awful experiences with women where I didn't have enough erections then I realized that the prozac may be the cause. I haven't taken it since 2014. Occassionally I was on zoloft to 20mg (the indicated dose for ocd) but I stopped them gradually. Since April 2017 I am not taking any medication but I have to confess that I have to tackle severe side effects such as erectile dysfunction, muted or inability to orgasm I noticed also impaired seven quality and sometimes the quantity was insufficient (almost zero). I am in a bad situation and I feel regretful for taking these drugs. I preferred to have OCD (or whatever mental illness is this) rather than facing impotence and inability to have children. Has anyone an idea about what am I supposed to do?
  8. I don't profess to know what it's like to live with anxiety, depression, or "medically diagnosed psychosis" in any form. Nor have I experienced the brain numbing side effects of the so called "Happy Pills" that are dished out like lollies to children and adults alike. And now Babies are the next largest growing market for these personality fixers. I live on the "Otherside". Firstly, I am the Mother, who against all pleading, and arguing with Doctor's (of all ranks) to not put my then "coming of a Meth Addiction" Son, onto Anxiety medication, was ignored. We are the people who stand by and watch as our loved one's fall apart slowly, in front of our eyes. The one's who are powerless to help and to fix it, because we are "out ranked" by the people who are supposed to know what is best. What I have done, is make it my life's work to understand Addiction and Anxiety - including coming off of these debilitating drugs and what happens within the brain from an unconscious, neuroscience and being in control of yourself perspective. I found this site because I too was looking for some answers on "cold turkey withdrawal". My Son decided to go cold turkey off of his Antidepressants 3 1/2 weeks ago. His decision? because he was sick of the night terrors, cold sweats and feeling like he was constantly in a fog. He asked me to help in my professional capacity and together we got through the hard parts. He still has a way to go, and I am not recommending going "cold turkey" However, what I can say is this: There IS clarity at the end of that foggy tunnel, allow your mind and body to adjust to this new drug free you. It will take sometime, it will happen. I am here to lend support just like all of the other amazing people in this forum . If I am able to support you by giving you any tools that will assist you. I will. Here is something I would like to share with you; You don't need to be strong. Realise, really understand and see, just how self empowered you have become, by being on this journey. And that you are absolutely AWESOME!!!! In those moments of doubt and grayness, give yourself permission to acknowledge just how amazing you are. You have come this far, keep going! xx
  9. Hello, I was diagnosed with fibro in 1994. I was just diagnosed by a rheumatologist with CSS - central sensitivity syndrome. A central nervous system disease/disorder that makes people hypersensitive to almost everything. Here are two studies that might be of interest: Fibromyalgia and Overlapping Disorders: The Unifying Concept of Central Sensitivity Syndromes by Muhammad B Yunus, MD -also: clinical review and education- JAMA April 16, 2014 volume 311, number 15 - Fibromyalgia A Clinical Review by Daniel J Clauw, MD. These articles show how the central nervous system plays a huge role in why so many of us have fibromyalgia CFS/ME, MCS-Multiple Chemical Sensitivities, etc. This explains why I've had so much trouble with antidepressants, benzodiazepines, and withdrawals, along with so many other physical and emotional symptoms
  10. Sterilized when Young in UK by Psych Drugs

    I was interviewed on the everyday psychvictims project. Share if you care.
  11. Hello . I took anti depressants ,anti anxiety , syzophenia medicines for one month . One doctor prescribed me these medicines after knowing the side effects in inherent I was scared to eat it and didn't want to eat it . I started suffering from acidity after eating I felt scared all the time 24/7 . My legs shivered atoagocally when I tried sitting still , my brain stopped working normally , I stopped eating properly , I stopped caring about everything , then I went to another psychiatrist . He told me I have been prescribed wronge medicines . Which is the syzophenia one cause I don't have syzophenia . I was shocked :((( cause I already ate it for 1 month ... I had to leave school when I promoted to class 9 cause I couldn't concentrate at all it's been a year I threw away those medicines and also complained to the psychiatrist about the side effects . I had brain pain after I stopped taking the 1 mg medicines each . Now I don't have brain pain . every time I tried studying my brain pained I was always a good student first time ever I failed I cried day and nighth I couldn't study and remember things whereas I was the best student layer after seeing my state my parents supported me and complained to psychiatrist . I'm still crying while writing this I thought I will never ever recover and I can't live with brain pain forever . I cried everyday and slowly the brain pain went . I'm healing . Thankgod I didn't eat it for 3 months but I completed 50% course . I think I'll fail next year too . Will I ever recover full my teachers noticed changes in me and told my parents what happened to me . I have heard from 2 people they suffered same things but got addicted to medicines
  12. Hi all!iam new to this site also new on antipsycotics. i believe you do great work about helping people from what i saw until now and i would like to say my problem to see if someone has experienced it and how can i possible deal with it.ok lets start recently my mother had an appoinment with her psyc doctor about me to talk about some issues.the days before that i did a minimun dose of MDMA .when i was on the docs office i started feeling fear and i said to him everything about what drugs i tried in the past.i was unable to conCetrate or talk normally i was feeling intense fear and panic for something bad will happen.the doctor said that iam on a psycosis episode and he told my mother that he needs to hospitalize me and to investigate what is happening to me.he prescribed me zyprexa about 10mg a day and after 3 days i went in to start the "therapy".the 1st days was ok the doctors was asking me things (for only 15-20 min a day) and i was really thinking that is a way to do good to myself cause i didnt knew. now the bad part begins. in day 10-12 on zyprexa i noticed changes in my breast start to grow but i didnt gave so much weight cause i was eating like a beast.then i started feeling like i could not have sex at all.i said these things to doctors and they were like "oh you might have that but they will go away".then i asked to stop the "therapy" but the doctor said he can not let me go out cause he thought i have an episode or something.my mother agreed and they kept me 5 more days in against my will.i refused to take anymore the zyprexa pill so they convinced me to take invega instead for 3 days.i took it cause i was something weird was goin on inside my head and i was convinced i need the pill cause iam mentally ill.anyway from that day i knew that keeping me in against my will and giving meds is illegal and the only thing i want was to go out and stop the pills(extremely difficult).at least i did it i went out of there but on the 17 day with a lot of pressure SO it might be a short time(21 days zyprexa and invega)taking that pills but i noticed these symptoms and i want your help (ITS BEEN A MONTH IAM OUT OF THESE DRUGS )BUT STILL HAVE THOSE SYMPTOMS my breast grew (not noticable from others but i believe that is the start of man boob thing) i have no libido lack of motivation lack of concentration anhedonia muscle stiffness some tremors on muscle still anhedonia depression more than ever feeling like a zombie lying in a bed all day suicidal thinking i want you to focus on the breast enlargement (man boob thing) and and the sexual dusfuntion am i have to be like this forever?anyone had gone through it ? also i have to say that i did hormonal test and my prolactin levels was back to normal and the testosterone levels was good too but my breast is still bigger and my libido and my sex drive is still messed up. i now that is not a serious thing to talk about but i need help and iam despaired i dont know what to do my parents and doctors dont believe me about all these things. also dont forget to say iam a mucisian iam playing drums and have a lot of interest on sports like skate and football.its like i lost my skills my interest i cant listen to music like i did and i cerntailny believe my legs are damaged due to the movement disorders now iam stucked in home crying and do nothing only searcing for other cases like me to reliefe the pain HELP I THINK MY LIFE SCREWED FOR EVER NOT LOVE MY SELFE ANYMORE ETC AND ALL THAT FOR 20 DAYS thank you for listening me
  13. Hi, I think lately I've been under covert medication. Anybody recognizes these symptoms with any antidepressant or antipsychotic? Thank you in advance. -Extreme photophobia (light hurts even at night with street lights or car lights) -Excess of fat in your stools (daily) (soft, greasy and pale yellow stools) -Urgency to urinate constantly -Lack of concentration -Feeling cold all the time but sometimes you feel heat intolerant (even when you are in direct sunlight you feel almost hypothermia) -Acathisia or restless sensation all the time -Racing thoughts all the time -Extreme Insomnia -Unability to achieve a lasting erection and difficult to achieve orgasms -Darkening and thickening of your hair, not only body hair but face and head (you have brown hair and the suddenly you have black thick and damaged-like hair) -You feel you cannot learn easily and you have a really hard time memorizing things you could easily do -You keep sweating and sweating but at the same time you have dry skin and sometimes lack of sweating in your face (cold, clammy skin) -You leave a weird odor in your clothes, always, even if you bathe yourself well -Dry mouth and bad breath even if you wash your teeth -ANNOYING muscle tightness (it feels like you just cannot relax your muscles and all the time you feel like if they are pulling) -Feeling like walking as a drunk or you feel you don't have stability as you walk -Lack of judgment, (getting very emotional out of nothing or not really seeing the whole picture of situations) -You feel like you are more complaisant that normal (agreeing things you normally don't and feeling like you worry about what others can say about you when you normally don't) -Abnormal euphoria just because everything -Mood changes (from euphoria and being very emotional to rage and depression) -Losing sensation of your body (you touch yourself but it feels like you don't feel anything) -Pallor -Abnormal healing of wounds (I could have a cut but the wound won't heal as fast as before, it would just take weeks to properly close) -Wanting to talk and verbalize everything nonstop -Constant gum bleeding (very sensitive just by brushing teeth) -Strange change in food's taste -Fatigue alterning with periods of extreme energy and I-can-do-it-all periods -Feeling like you were running and agitated most of the time -You cannot stop moving your feet -Weight gain -Dilated pupils -Dry lips -Numbed tongue -Difficulty in speaking (like you don't know the words to describe something totally easy and normal, stuttering) -Dilated arm veins -Ear buzzing -Increased sensitivity to normal noises -Difficulty to do maths -Eye bags and looking ill in general. -Feeling suicidal -Looking yellow sometimes -Having foam in your urine sometimes. -Zero sexual arousal (it is like you do not feel aroused or have erections as you normally do) In general, feeling like you are totally drugged, in a dream, or as I have read, like if you were on cocaine. I would thank if someone would recognize these symptoms and tell with what kind of medication did you feel them as I suspect I have been under covert medication because I refused at first to take those things. It is a long story but I have been medicated wrongly because I have a tumor that causes me weird things and they thought I was depressed just because at first they didn't find anything. Furthermore, a lot of physicians just simply didn't know or explain weird symptoms like extreme photophobia. I swear I had to wear sunglasses even at night because that symptom was unbearable, it literally caused me pain in the day or even when I looked at the floor, strangely that was when I had dilated pupils, really big pupils. I don't do drugs and this happened overnight. The most weird thing is the photophobia, dilated pupils and muscular tightness for me, I was checked neurologically and everything was fine, no head tumors, no eye damage, anything at all. I suspect this covert medication because stubborn psychiatrists wanted to put me on medications and I refused completely because I knew something physical was wrong instead of just a "mental illness", whatever that means. Most of these symptoms suddenly started to dissapear a year and a half ago, gradually, and then I got like a withdrawal syndrome feeling suicidal, like I couldn't go out of bed, suddenly that euphoria went off and nothing would satisfy me at all, it is like a flat emotional response, but then you get depressed and angry, nausea, sweaty.. a total mess. Now, after all that last stir, the last months I have been feeling more like myself and all those symptoms dissapearing but I want to know because all of this seems so suspicious to me. Now, my original physical condition it is not treated so you cannot blame the getting better to a treatment to the physical ailment. Another thing I would want to ask is that if a withdrawal syndrome can last up to many years after you have taken the medications, because I stopped taking those things by myself from one day to another without gradually diminish them and I was wondering if that withdrawal could have lasted by six years (which I don't think so), so my family would have decided to go on covert medication by psychiatrist orders or something or is just something else that I have in my body. I really feel like crap and as if my brain was shook and then you come back to normal life after (and that is something that tumor doesn't do and do not behaves like that).
  14. If you or a loved one had a child with a birth defect after taking antidepressants during pregnancy and you are willing to be interviewed about your experience, PM me and we'll talk. I am a free-lance writer specializing in medical harm.
  15. Hi! I'm Britt777. I joined this site to figure out what is causing me numerous symptoms. Here is my brief story: Took Lexapro for about 3 years or more, came off of it Tried Trintillex and Brintillex, didn't like the way it made me feel Doctor then tried Fluvoxamine 100mg and took that for 7 months. He decided to add Wellbutrin (Bupropion XL 150mg) along with it. A month later I ask to stop Fluvoxamine (Luvox) because I felt like I was experiencing "depersonalization" or pretty much felt like life was not real and was a dream. So, at that appointment he told me to stop the Fluvoxamine and upped my Wellbutrin to 300mg once a day. The first day from this switch I felt great. Then the second day came... had nausea, lightheadedness, dizziness, "brain zaps", increased tinnitus (ringing in the ears), blurry vision, feeling like I could pass out, headaches, head pressure, and crazy fluctuating heart rate. (Today I had a heart rate of 100 and dropped to 70 within 5 minutes without doing anything different.) This is day 7 since the switch. I just want to find out if it's withdrawal symptoms from the Fluvoxamine since he didn't advise me to taper or if it's a reaction to upping the Wellbutrin.
  16. In-depth article about how genetics informs how you process drugs, and also how it affects drug interactions, and the genetic tests used to determine if you will likely react badly to a drug or not. It's written by a forensic medical examiner. I've only skimmed it but seems well worth a read through. https://www.madinamerica.com/2017/01/cyp-testing-prevent-dangerous-adverse-drug-reactions/ CYP Testing to Help Prevent Dangerous Adverse Drug Reactions By Selma Eikelenboom-Schieveld, MD January 24, 2017 Readers of this website might be aware that antidepressants can cause suicide, other violent behavior and even homicide. These can be side effects or adverse drug reactions from the medication taken. Not only can antidepressants cause these side effects, but basically every psychoactive medication can put patients at risk. Few people may know that there are DNA tests that can identify individuals who might be prone to these adverse drug reactions.1 To understand what kind of information such a test would provide, it might be helpful to explain the science behind these DNA tests. In general, human cells contain 23 pairs of chromosomes. The father donates half of the chromosomes; the other half comes from the mother. Every chromosome contains many genes. A gene is the part of the DNA that codes for proteins, and proteins cause hereditary characteristics to be expressed. A gene can have two forms, called alleles. If someone inherits the same allele from the father and the mother, the person is called homozygous for that trait; if they are different, the person is heterozygous. Medication needs to be metabolized to be expelled from the body. This is done by certain proteins called enzymes. Most medications that interact with brain chemistry are metabolized by an enzyme system called Cytochrome P450 (also known as CYP450 or P450). There are many different P450 enzymes, and they are divided into families and subfamilies. Cytochrome P450 family names are denoted by an Arabic number (e.g., CYP2), the subfamily by a Roman uppercase letter (e.g., CYP2D), and the individual enzymes by another Arabic number (e.g., CYP2D6). The alleles are indicated with an asterisk and a number, separated by a forward slash. More at above link...
  17. Hello All- Thank you in advance for any tips or support you can provide. I found this forum by accident, and am really struggling. By way of introduction: I am currently 27 years old, and was misdiagnosed in my adolescent years, sending me into a dreadful spiral of reliance on antidepressants and psychoactive drugs for over 10 years. About two years ago I found a wonderful doctor who saw that these were unnecessary and has been guiding me through the process of tapering off of ALL Medication. I have already been able to completely go off of Lamictal (originally 300mg), though it took me a year, and am now in the final stages of tapering off of 100mg Pristiq (has been an ongoing process since this past summer 2015). As of yesterday, I was taking (roughly since they're tough to cut without crumbling) 6 mg of Pristiq and since I cannot really cut them any smaller, today is Day 1 of being at 0 dosage. My doctor was transparent with me in that this may get messy, and it is difficult to predict how anyone will react to this final cut. All along with the cuts I have experienced: extreme anxiety (subsides as my body adjusts) Depersonalization or feeling totally light-headed and "stupid" Headaches Terrible stomach upset I am so fearful of this last cut because I know it will be the worst....yet I know that the positives of my doing so will outweigh whatever costs I need to incur to get there. Does anyone have any insight for folks who have been on high doses of Pristiq for 8+ years and may give me an idea of what to expect? I feel that's the worst part- not knowing what to expect. Many of these posts involve folks who have been on for just a few years, so I am curious as to how the long-term dependence will manifest itself for a case like mine. I am grateful for any words of wisdom you can provide. Thank you!! KimT1717
  18. Hello everyone, I was diagnosed with Anxiety disorder, agoraphobia, claustrophobia, and severe depression, few years ago. I was on Nexito (Escitalopram) and Rivotril (Clonazepam) for almost 3 years. I went off the above medications 4 months ago, i.e., in January 2016. Withdrawals started after a month. My shrink prescribed me with Stablon (Tianeptine) 12.5mg twice a day, to fight the withdrawals. Three weeks into the new drug, and I started experiencing the following symptoms. Head ache/stuffy head Muscle ache Weakness Joint pain Dry mouth Dizziness Anxiety Suicidal Thought Mood swings Loss of taste I immediately contacted my shrink and he put me back to Nexito and Rivotril. Upon asking whether the above symptoms were the side effect of Tianeptine, he simply avoided the question by claiming Tianeptine to a very mild drug. It has been 4 days now, I'm off Tianeptine, and I am feeling much better. Not completely though. My main concern here is the loss of taste. Been 4 days and I cannot taste food at all. Even if I am not eating anything, there is this greasy metallic feel that persists. I went to an ENT yesterday and he concluded it as a reaction to Acidity, and prescribed me with general antacids, lactic acid bacillus capsules, and mouthwash. Since I do not know why it happened and what exactly it is, I am concerned whether I am on the right line of treatment. If anyone out here can help me on this, I'd be grateful. Thank you!
  19. http://www.madinamerica.com/2016/04/legal-journal-says-antidepressants-can-cause-violence-and-suicide/ Legal Journal Says Antidepressants Can Cause Violence and Suicide April 18, 2016 Antidepressants have been reported to cause a state called “akathisia,” where people feel extremely agitated and restless and may become preoccupied with thoughts of violence. In a new article, to be published in the latest issue of the Journal of Forensic and Legal Medicine, researchers investigate the role of antidepressants in three recent murders. The researchers, a medical specialist and a forensic psychiatrist and pharmacogeneticist, suggest that tests may be done to assess the role of antidepressant toxicity in violent events that may affect legal determinations, potentially even absolving people charged with homicide. The “new generation” antidepressants, SSRIs and SNRIs, appeared in the 1980s but, according to the reviewers, “their adverse effects and clinical trial data have not been fully disclosed.” In 2004, the FDA published a public health advisory warning of worsening depression and suicidality in some patients being treated with antidepressants. In 2007, a Black Box suicide warning was extended from just teenagers and suggested monitoring all patients up to age 24 for anxiety, agitation, panic attacks, hostility, impulsivity, and akathisia. Recent findings show an increased risk for violent crime in young adults taking antidepressants and a groundbreaking reanalysis of the infamous Study 329 on the effects of Paxil on teens found a heightened risk for suicide that was not initially disclosed by the drug companies. The authors report that genetic variations in metabolism affect how individuals react to antidepressants and that research indicated that “ultra-rapid metabolizers” may be at an increased risk for changes in behavior. More at above link...
  20. Suziestarshine hello there

    Hello there everyone, recently took the plunge into tapering off of sertraline after our 2 year love affair began to sour. I'm no newbie to anti depressants and have been battling depression for most of my life. I had my first episode when I was 15 which escalated to a suicide attempt at 16. Since then I have had 3 major episodes the last of which began early 2012 but I let it run and then New Year's Day 2013 I experienced the biggest meltdown of my life so far. My GP began my treatment with citalopran but my body was not comfortable with its side effects so this was replaced with sertraline. Dosaged started at 50mg and climbed to 200mg by October 2015. For the most part I have enjoyed my time on sertraline but I now feel more and more side effects manifesting such as rapid weight gain, insomnia and general feeling of weirdness. I really want to kick this drug and began to stop taking them. I had no idea how bad it would be and have had to return to my normal dose. I was experiencing headaches, dizziness, nausea and irratability. I began researching and came across this site and was comforted by the knowledge that I was not the only one. I am now planning to taper myself off sertraline so wish me luck guys.
  21. Congress Proposes Research on the Link Between Psychiatric Drugs and Suicide By Chuck Ruby, PhD Featured Blogs March 30, 2016 Congressman David Jolly (FL-13) has recently introduced the Veteran Suicide Prevention Act (H.R. 4640). The bill calls for the VA to study veteran suicides over the past five years and to determine what extent psychiatric drugs are implicated in those suicides. The International Society of Ethical Psychology and Psychiatry (ISEPP) has long been concerned about this issue, and more broadly, how our veterans and military members suffering from the horrors of war and other traumatic experiences are being treated. I sent letters of support to Mr. Jolly’s office, offering ISEPP’s assistance in any way possible. In 2012, ISEPP launched “Operation Speak Up” (OSU) as a response to the alarmingly high suicide rate of veterans. The name signifies our desire to help veterans speak up, rather than being shut up with psychiatric drugs. Although it started as an effort to encourage Congress to consider a non-medical model approach to helping those suffering from trauma, it quickly turned into a grassroots and consumer focused endeavor from the ground up under the leadership of our OSU Director, Mary Vieten, Ph.D., ABPP, U.S. Naval Reserve Commander. Mary has since made great strides in partnering with Melwood, Inc., a non-profit organization dedicated to helping people with disabilities in the greater Washington DC area. Together with Melwood’s support and funding, Mary has created a program called TOHIDU (a Cherokee word meaning “peace of mind, body, and spirit”) as a wonderful alternative to conventional treatment. You can see more about TOHIDU here. Mr. Jolly’s bill will be the first to establish congressional oversight of this alarming problem of using psychiatric drugs shotgun style to quiet the screams of trauma. Despite the increasing concerns of the deleterious effects of psychiatric drugs, they continue to be the mainstay form of treatment within the VA and Defense Department, as they are on the outside. This has to change.The extant research makes it abundantly clear that psychiatric drugs do not correct chemical imbalances. It would be better said that they cause chemical imbalances. They artificially alter brain chemistry in ways that are not clearly understood, and that numb important emotions that signal meaningful issues in our lives. The brain tries to counteract their effect by making changes in how neurotransmitters are used. The person experiences these changes in very agonizing ways, the most worrisome is called “akathisia,” or a state of agitation, restlessness, and a terrible sense of not feeling welcome in one’s own skin. This can lead to unpredictable irritability and violent behavior, including violence toward oneself. To read more on this, see ISEPP’s White Paper. More here: http://www.madinamerica.com/2016/03/congress-proposes-research-on-the-link-between-psychiatric-drugs-and-suicide/ Also on that page is information about how to contact Congress to express your support for this bill. It would be a great idea to also encourage them to investigate the suicide-drug link in other populations too!
  22. Hey everyone, I am new to the site. I wanted to share my experience with my successful taper off of the antidepressant Trazodone. I know how awful the withdrawal and discontinuation syndromes can be. I started taking Trazodone after a bad series of panic attacks and constant edgy anxiety, brought on by my brief usage of the drug Wellbutrin. I know this drug has helped people, but for me, it was very bad. It nearly brought me to a psychological breakdown. I was driven to the emergency room, from there I was taken off the drug (after not sleeping for about 4-5 days, I took around 7 Ativan to finally knock me out.) Great time! From there my doctor prescribed to me Trazodone, upon my reporting my constant agitated state, anxiety and repeating panic attacks, and lack of sleep. That drug is ridiculous. I used it for about a year, naively. When I couldn't sleep, I'd up the dosage a bit. And then suffer intense spells of an anxious and panic stricken state for hours on end. At its worse, I was up to over 300mg a night. After a scary and messed up winter on it, I decided that it was not helping anything. My panic attacks were not any better, my anxiety levels off the charts. Doing daily things became a tremendous struggle. I remember shaking in terror trying to open files on my computer. It was messed up and bad. It may have been some of my regular anxiety kicking in as well. I'm not sure if it was fully the effect of the drugs. But here's what I do know. I am completely off the drug. I'm on no drugs. None! I sleep like a baby most nights. I haven't had a panic attack in over a year. My anxiety, when taking the Trazodone, I would say was at a 10 out of 10 (10 obviously being the worst). I'm an anxious person, prone to it, but after tapering off Trazodone and going drug free, I felt it drop to a 0.5. 10 to 0.5! I practically feel normal. I am actually adjusting my new opinion of normal, as I occasionally have very mild bouts of anxiety. But who doesn't? Anyways, I wanted to post this in hopes someone struggling through the taper and the discontinuation would read it and know that there IS light at the end of the tunnel. I remember the wondrously dreadful, distressing, horrific and disturbing things I went through getting off of it. I tapered off rather quickly - 300mg to 0 over about 6 months. I would make big leaps and cut a quarter of the pill off some nights. But I would pay for it later in terrible insomnia, unsettling mental flashes, body twitches, miniature seizure-like jolts. Rapid eye twitching, a deep and utter terror and fright, and long nights of uncontrollable sobbing. A creepy sense of tunnel-vision throughout the day. I went through it all, and luckily for me, only about those 6 months. I know people who go through withdrawal for very long periods of time. But what I wanted to really say is, to endure it. Buckle down and dig in for it. Because it's worth it in the end. It may seem that it will never let up. It may seem there is no end in sight, and that the psychological predicament you feel trapped in will never come to an end. But it will. Steadily. A while later after I was feeling much better, I wrote in my records that it resembled the tapering process to the time it takes to grow your finger nails. Or growing hair. From day to day, things don't really look different. But over a long period of time, you will notice changes. But that's how slow it goes for some, many, unfortunately. Just bite down and give it hell and get through it. The other thing is, trust your brain. It will recover, and reconnect the wires that got crossed. Eventually, and there is going to be a lot of trial and error for it to finally reconnect everything the way it was. But it will. Your brain is constantly renewing itself, reworking, adapting. And with the lack of drugs in my brain, it could finally get to work reconnecting everything in a natural manner, without any interference. I never thought I would be able to do a bunch of things back then. I never thought I would be normal again, go on dates, hang with my friends without losing my mind, work on projects, go out into the world. Seriously. I wrote it all off, I felt hopeless. But just, if you can even find the tiniest sliver of strength to keep going, to push on, to go forward, do it! Things, eventually, they will get better. Much much better. I hope this finds whoever is reading this well, and if you are going through it, to keep fighting it. Things get better, I promise! N
  23. If the theory of up-regulated serotonin receptor sites is true as an explanation for depression, this could be a compensatory measure taken by the brain as a result of anxiety, acute stress responses, environmental factors, and even other medications. Seems to me that only non-pharmacological interventions would have any real long-term therapeutic value. Ie. cognitive behavioral therapy, altered thinking process, etc. Any thoughts?
  24. Peter Gotzscke Melbourne Talk

    Peter Gotzschke recently came to Australia, and toured around our cities, lecturing sometimes 3-5 times in each major city. He had an important message to bring, and his reputation preceded him - lots of pdocs came, and other care providers. Some of the pdocs argued with him (in Brisbane) about the value of "forced treatment" and neuroleptics, insisting that the benefit of these drugs "saved lives." Here is the Melbourne talk:
  25. TMG (Trimethylglycine)

    The following was posted by a reviewer on the iherb site, offering her responses to the supplement 'Jarrow Formulas, TMG, Trimethyglycine. I take the liberty of posting it here as I was struck by how much benefit she claims to have derived from TMG. I am NOT in any way involved with the sale of this or any other health product. The following testimonial is copied from: http://www.iherb.com/product-reviews/Jarrow-Formulas-TMG-Trimethylglycine-500-mg-120-Tablets/141/?p=1&fr=5 "TMG is a godsend. When I went off antidepressants rather suddenly and was fishing around for something to stop panic attacks and intense bad moods, TMG was the first consistent improvement. Four years later, it is still an indispensable part of my regimen. Perhaps its most important effect is recycling homocysteine into SAMe, which has antidepressant effects. Unchecked homocysteine sensitizes neurons to glutamate toxicity, and probably harms new neurons trying to grow in the hippocampus. Other B-vitamins have also helped me, especially B-2 and B-6 (pyridoxamine), along with fish oil and a non-choline source of uridine (for example magnesium orotate, or triacetyluridine). Some of these will help migraines and focus along with mood. I take 500 to 1000 mg TMG a day; much more may raise cholesterol. Don't mix with acetyl-l-carnitine (and in fact, if you're depressive, I'd advise against acetyl-l-carnitine altogether, thanks to its acetylcholinergic activity). TMG raises carnitine levels itself, and has a mild choline sparing effect. SAMe, by the way, is similar but not so safe; the surge in SAMe levels will create a surge in homocysteine. I tried combining the two, hoping TMG would recycle the homocysteine back SAMe, but I've found TMG on its own most stabilizing and effective."
×

Important Information

By using this site, you agree to our Terms of Use.