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uncomfortablynumb: Withdrawal Symptoms or Anxiety/Depression


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#145 uncomfortablynumb

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Posted 08 February 2016 - 11:05 AM

SG,

How long was it before you reinstated Effexor? What were you experiencing in withdrawal? And has everything stabilized now?
I have a similar med use history and wondering how things panned out.
10/2006 - Celexa 4 wks - not effective 10/2006 - Effexor - kicked in within 4 wks at 112mg dose. Over 3 yrs worked fairly consistently well but began having relapses of depression and anxiety. Upped dose to 150mg or 187mg and was fine. On Effexor, I was always taking workout energy supplements2009 - Effexor started pooping out and tried adding Abilify to no avail. Then tried Pristiq which also didn't help.2010 - Back on Effexor at 150mg. Surprisingly worked again, but less effective. Slowly started losing Effectiveness over 3 years.2013 - tried Zoloft, Nortriptyline, and Wellbutrin. Each separately for 4 weeks. Didn't give longer because they all were causing heart and other issues. 2014 - back to Effexor and it worked just to get me functioning. 04/2015 - off Effexor after a 2 month taper from 150mg. Was doing well for 3 months off meds but still taking pre-workout supps. 07/2015 - stopped taking my pre-workout energy supplement because I was abusing it and taking it for long periods. Stopped that cold turkey and quickly fell into depression and anxiety. 07/2015 - back on Effexor. From July to August slowly increased dose to 187mg and it didn't do anything. 09/2015 - began weaning off Effexor 37mg drops every wk. Then half of 37mg for a week to nothing on Oct. 16. Cue W/D symptoms 11/01/2015 - reinstated 37.5mg Effexor for a day and quit because it made me feel worse. Then 10 beads. Gave up. 12/01/2015 - Doc prescribed Remeron for severe insomnia. Took 15mg for 2 days and 7.5 for 4 days and stopped. Realized this was not a good long term solution for a withdrawal symptom.
Experiencing severe insomnia dizziness,headache,brain zaps. Severe anxiety and depression. Mind is mostly blank - difficulty thinking/concentrating. Hard to socialize. Poor long term memory. Depersonalization/unreal feeling. Emotional flatness. No interest or motivation.

#146 uncomfortablynumb

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Posted 08 February 2016 - 11:36 AM

Alto, For melatonin I am trying 1.5mg sublingual. But it is not helping. Should I try less? I know you have mentioned in posts that sometimes less is better.
10/2006 - Celexa 4 wks - not effective 10/2006 - Effexor - kicked in within 4 wks at 112mg dose. Over 3 yrs worked fairly consistently well but began having relapses of depression and anxiety. Upped dose to 150mg or 187mg and was fine. On Effexor, I was always taking workout energy supplements2009 - Effexor started pooping out and tried adding Abilify to no avail. Then tried Pristiq which also didn't help.2010 - Back on Effexor at 150mg. Surprisingly worked again, but less effective. Slowly started losing Effectiveness over 3 years.2013 - tried Zoloft, Nortriptyline, and Wellbutrin. Each separately for 4 weeks. Didn't give longer because they all were causing heart and other issues. 2014 - back to Effexor and it worked just to get me functioning. 04/2015 - off Effexor after a 2 month taper from 150mg. Was doing well for 3 months off meds but still taking pre-workout supps. 07/2015 - stopped taking my pre-workout energy supplement because I was abusing it and taking it for long periods. Stopped that cold turkey and quickly fell into depression and anxiety. 07/2015 - back on Effexor. From July to August slowly increased dose to 187mg and it didn't do anything. 09/2015 - began weaning off Effexor 37mg drops every wk. Then half of 37mg for a week to nothing on Oct. 16. Cue W/D symptoms 11/01/2015 - reinstated 37.5mg Effexor for a day and quit because it made me feel worse. Then 10 beads. Gave up. 12/01/2015 - Doc prescribed Remeron for severe insomnia. Took 15mg for 2 days and 7.5 for 4 days and stopped. Realized this was not a good long term solution for a withdrawal symptom.
Experiencing severe insomnia dizziness,headache,brain zaps. Severe anxiety and depression. Mind is mostly blank - difficulty thinking/concentrating. Hard to socialize. Poor long term memory. Depersonalization/unreal feeling. Emotional flatness. No interest or motivation.

#147 SquirrellyGirl

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Posted 08 February 2016 - 12:40 PM

Hi UN 

 

I was in protracted withdrawal that unfolded over 10 months.  At a little over 8 months, I was so bad off that I went to my p-doc begging for relief.  None of the many doctors I had seen since I went off recognized that it was Effexor WD, of course.  I tried to reinstate myself but it was a disaster.  I had been taking serotonergic supplements trying to replace the Effexor, and stopped them the day before reinstating, but I think I went into mild serotonin syndrome.  I saw my p-doc a few days later andI was put on mirtazapine, which helped me sleep and eat, but very quickly I was at almost the highest dose and completely apathetic, still unable to bathe and feed myself.  Agoraphobia kept me on the couch.  I went back pleading for help again, and this time my doc suggested adding Effexor since I had "tolerated it" well in the past.  37.5 mg.  I think I had come down quickly off 75 mg, so half.  I hadn't found SA yet.  I think this was about 7 weeks after my attempt to reinstate.  Also, I had tried to reinstate first with 18.725 but then went up to 37.5 mg, but on the back of the supplements it was too much.

 

Within an hour of this second reinstatement, my symptoms abated, like the clouds parting and the sun shining through.  I don't know if it was the combo of mirt and ven.  Mirt helped initially but very quickly pooped out or just couldn't hold up to the Effexor WD.  The doctor said the combo was syndergistic.  So, not sure what really happened there, if it was the two working together or simply that I got a "fix."  Whatever the case, I was dramatically better, no side effects or paradoxical response.  I know this is risky, and the reinstatement dose was pretty high and had it gone bad, it surely would have been REALLY bad. I just got lucky.

 

After 12 years on Effexor (ven) and eight years on other ADs before that, I think my nervous system was so dummed down that it just couldn't upregulate very quickly when I was off the meds.  I now see that I will have to do a very slow slide off, taking it agonizingly slow the lower I get, in hopes my nervous system will take up the slack and upregulate as I go.  I can say for sure that this whole experienced has revamped my conviction to get off these poisons completely.  I now see that the life I was living while on was a mere shadow of the life I could have had. I am now doing the emotional work I should have done years ago before meds, but no one guided me or I was unable to take in the type of therapy I was in at the time.

 

What was I experiencing in WD?  Well, I complicated matters by coming off a lifetime of birth control at the same time, realizing I was probably in menopause.  So, initially I didn't feel any withdrawal.  No brain zaps, ever.  The symptoms I first had were cog fog bad.  I was so scattered and unable to remember what I was doing from one minute to the next, so when a friend suggested that I had ADD, that he had always thought I had it, I latched onto that and got tested.  Well, I tested negative, but the psychologist declared that I had tested positive for depression, anxiety and OCD, but there's meds that can make you feel "normal!"  I had lots of trouble reaching for words, articulating myself, lots of memory issues, etc.

 

I wish I had kept better track of what was happening when.  I do know that I was starting to have severe sweats, day and night, where the sweat would be dripping off my face.  At night, I would be literally drenched, sheets top and bottom soaked, sweat rolling down my skin, and then I'd be freezing.  I also noted that my pulse had gone up.  I had a dental appointment that February where it was 99, and the hygienist commented on it.  I began taking my blood pressure and pulse, and daily it was high 90's and my BP had climbed from my norms.  I also would wave waves of a burning sensation over my torso, especially at night.  I'd be throwing the covers off and then covering up, all night long.  I thought it was related to menopause so pursued hormone testing.  My numbers were full on menopause, and I began bio-identical hormone replacement therapy, but it did nothing to improve the sweats and mood issues.  I think the mirt began to cut into those symptoms, lessening them, or the HRT finally started helping, not sure.  Oh, I developed PSSD, not that I even cared to have sex through all of this.

 

I latched onto the "there's meds that can make you feel normal" notion and went to another p-doc who declared I was asexual (the reason I wanted off to begin with) and so she put me on Viibryd since it isn't supposed to interfere with sex drive etc.  The low dose went ok, but when I bumped up to the next dose, all hell broke loose!  I had insomnia with extreme anxiety at night, couldn't sleep, had the worst anxiety and depression of my life.  Indeed, an adverse drug reaction!  Went off real fast, but that kindled me, I think.  Don't know if that is the right use of the word, but after that I began to have GAD, fear, doom, dread, worrying about death, the death of my parents, husband, my being alone in old age, what would become of me, terror over climate change and what would the world be like....on and on.

 

I guess I was having wave after wave of those kinds of symptoms, so the anxiety and depression were intractable from about two plus months before I ended up on mirt.  I had told my parents what was going on with me, and so they were calling daily, worried to death.  Yes, there was suicidal ideation in there, too.

 

I have PTSD from all of this. 

 

Now I was on two meds, not one.  I learned about SA from someone on here whom I met outside, and once I got educated, I was hell-bent to come off.  Tapering has gone very well, though I've had a couple of periods like I am in now, where anxiety and fear have come up, not to the degree I had in WD but still uncomfortable.  

 

I am in progress, so can't give you the happy ending story, yet.  I'm at about 27.5 mg Effexor and 14 mg mirtazapine, down from 37.5 and 37.5 mg respectively.  I am very happy to have gotten this far without too much agony.

 

I am with you on the emotional flatness, no interest/motivation.  I had gotten some of it back until this wave.  I actually headed out and did some outdoor projects that I had been dragging my heels on, and it felt good.  So, I think there is hope there.  Though I can get my animal chores done and train my dogs for herding competitions coming up, I still don't crave to do it.  No way could I go out and look for a job, nowhere near ready for that.

 

I'm sorry you are in the thick of it, dang it is such a nasty place to be.  I have definitely improved hugely over that stage. I hate that I ended up on Remeron.  It made me crazy to realize I was now on two of the hardest drugs to get off of!

 

As I reflect back, I had gone up quite high on the ven at one point, at least 225 mg if not more, and then came down to 75 mg over years.  I went down to 37.5 mg for awhile, and know that I had WD but didn't recognize it as such.  I wish I could remember what I did exactly with down-dosing, since I did it on my own. Memory has really trashed by all the years on it.  I can't remember if I went back to 75 for a bit before tapering, or if I never did go back to 75 but was planning to before deciding to go off that summer. I just wasn't "present."

 

Where are you at with your taper?  Are you still on Effexor or off now? Your taper was about as fast as mine back then.  Trying to figure it out from your sig.  You gave upon 12/01/15 but do you mean you went off completely?

 

SG

 

Had I known I was in withdrawal and learned about everything here, maybe I would have been able to forge ahead.


Prozac 1995-1999, don't remember the dosage; Wellbutrin 1999-2002? Don't remember dosage though it was in the 300 mgs range
Effexor XR 2002-2014 up to 225 mg at one point, down to 37.5 mg towards end but back up to 75 mg in 2014; now realize I had W/D as I dropped down, memory very poor about history.  Did fast taper, don't remember details, around August 2014.
Took Sam-E 200 mg AM and 500 mg L-tryptophan PM Sept.2014 to January 2015

Doing poorly, put on Viibryd 10 mg for 1 wk, 20 mg for several days, BAD ANXIETY, fast taper to 0 in a week; back on Sam-E 200 mg AM and L-tryptophan 500 mg PM until April 10, 2015; doing very badly, put on Remeron 7.5 mg start April 15-April 30, 2015; Increased Remeron from 7.5 mg/day to 37.5 mg by May 22, 2015; still doing very badly,

June 1. 2015 Reinstated Effexor XR 37.5 mg, Remeron dropped to 30 mg PM. Immediate relief of symptoms, like nothing had ever happened!  On p-doc's orders went up to 75 mg Effexor June 11-12, then back to 37.5 mg when I realized all the hell I had been through before was WD from Effexor!  Joined SA and began tapering both too soon one month later.

8/22/15: Effexor to 30.75 mg, Remeron to 22 mg. 9/9/15 Effexor 30 mg/Remeron 21 mg. 9/24/15: Remeron 19 mg. 10/25/16: Remeron 17 mg. 11/14/15:  Effexor 28.5 mg 12/2/15: Remeron 16 mg. 12/5/15: Effexor 28.1 mg. 12/17/15: Remeron 15 mg. 1/26/16: Remeron 14 mg. 3/22/16, Remeron 13.5 mg and Effexor 25.9 mg (had nudged it down by fraction of a mg since Dec).  4/28/16: Remeron 13 mg, Effexor 25.5 mg.  5/21/16: Remeron 12 mg, Effexor 24.75 mg.  6/17/16, Effexor 23.25 mg, Remeron 11.6 mg. 7/12/16:  Remeron 11 mg, Effexor 22.12 mg.  9/22/16:  Effexor 19.5 mg, Remeron 9 mg.  As of 4/12/17:  Effexor 12.4 mg  Remeron 5.9 mg.

 

My intro: http://survivinganti...e-2#entry196679

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.


#148 KarenB

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Posted 08 February 2016 - 02:33 PM

I'm talking about whole raw oats.  (Not the quick-cook kind).  They might have different names in NZ).  In summer I don't cook them.  The soaking softens them and breaks down something-or-other which makes them more digestible.  I think it's what people used to call 'Bircher Muesli'.  In winter I soak them then cook them into porridge. 

 

Dunno if it boosts serotonin or not.  I'm not much on the science of things.  All I know is it feels soothing to eat, and then I read that oats are in fact a soothing food. 

 

That serotonin imbalance theory is a proven lot of rot, however once we've taken SSRIs then it does get out of balance.   

 

Actually, all grains benefit from being soaked - rice, oats, wheat... Much gentler for sensitive guts.


2010 May Fluoxetine 20mg. Raging mostly stops, become more functional.
2011 February Escitalopram 10mg (sudden switch). 2012 January Escitalopram 20mg.  2013 Early June Feeling great, decide to taper. Doc advises alternate days 20mg/10mg for 4 weeks.  Late June Steady. Drop to 10mg daily. Early July Not coping, raging, flu symptoms, shaky, anxious, low, spaced-out, self-destructive.  Mid July Return to alternate days 20mg/10mg - minimal improvement. Early August Return to full dose 20mg. Lost.
2014 February Switch to Venlafaxine. (First reduced Esc. to 10mg/day for a week) Feb-April Lost, 'light' self-harm, exhausted.
April Increase Ven. to 150mg/day. Dizzy. July 75mg twice a day to improve dizziness. Deep depression remains.  2015 Feb Vigilant dose spacing partially eases dizziness. Mar Switch to Effexor 75mg 2x/day. May Cut 10% to 135mg - bad w/d 2 mths, held 1 mth.  Aug 1.3% cut - bad 1mth, held 1mth. Oct 4 wkly 0.4% cuts held 6 weeks. Jan 2016 2 wkly 0.4% cuts. 8 month hold. Sept Wkly cuts: 0.5%, 3 1% cuts.  Oct 4 wkly 1% cuts, hold 3-4 weeks.
Supplements: Fish oil, vitamins E & C, magnesium, iron, MSM, oat-straw tea, nettle tea.  My story of healing: ContinuedHealing

***I am not a doctor or counselor; please do your own research and be prepared to take responsibility for decisions you make.*** 

           'The possibility of renewal exists so long as life exists.'  Dr Gabor Mate.


#149 SquirrellyGirl

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Posted 08 February 2016 - 04:12 PM

 

 

That serotonin imbalance theory is a proven lot of rot, however once we've taken SSRIs then it does get out of balance.   

 

 

Thank you for the belly laugh!  And yes, we're definitely out of balance ON the drugs and coming off the drugs.

 

Here we have what's called steel cut oats.  I think the original brand I used to buy in a metal tin was Irish.  They are who kernal oats that have been cut in half, I guess.  Makes for a wonderfully chewy porridge, compared to the mush crushed oats that we Americans usually make oatmeal out of.  I had some oats for breakfast this morning after reading your piece on it here, Karen!  

 

Give it a try, Numb - I think it helped me today!

 

SG


Prozac 1995-1999, don't remember the dosage; Wellbutrin 1999-2002? Don't remember dosage though it was in the 300 mgs range
Effexor XR 2002-2014 up to 225 mg at one point, down to 37.5 mg towards end but back up to 75 mg in 2014; now realize I had W/D as I dropped down, memory very poor about history.  Did fast taper, don't remember details, around August 2014.
Took Sam-E 200 mg AM and 500 mg L-tryptophan PM Sept.2014 to January 2015

Doing poorly, put on Viibryd 10 mg for 1 wk, 20 mg for several days, BAD ANXIETY, fast taper to 0 in a week; back on Sam-E 200 mg AM and L-tryptophan 500 mg PM until April 10, 2015; doing very badly, put on Remeron 7.5 mg start April 15-April 30, 2015; Increased Remeron from 7.5 mg/day to 37.5 mg by May 22, 2015; still doing very badly,

June 1. 2015 Reinstated Effexor XR 37.5 mg, Remeron dropped to 30 mg PM. Immediate relief of symptoms, like nothing had ever happened!  On p-doc's orders went up to 75 mg Effexor June 11-12, then back to 37.5 mg when I realized all the hell I had been through before was WD from Effexor!  Joined SA and began tapering both too soon one month later.

8/22/15: Effexor to 30.75 mg, Remeron to 22 mg. 9/9/15 Effexor 30 mg/Remeron 21 mg. 9/24/15: Remeron 19 mg. 10/25/16: Remeron 17 mg. 11/14/15:  Effexor 28.5 mg 12/2/15: Remeron 16 mg. 12/5/15: Effexor 28.1 mg. 12/17/15: Remeron 15 mg. 1/26/16: Remeron 14 mg. 3/22/16, Remeron 13.5 mg and Effexor 25.9 mg (had nudged it down by fraction of a mg since Dec).  4/28/16: Remeron 13 mg, Effexor 25.5 mg.  5/21/16: Remeron 12 mg, Effexor 24.75 mg.  6/17/16, Effexor 23.25 mg, Remeron 11.6 mg. 7/12/16:  Remeron 11 mg, Effexor 22.12 mg.  9/22/16:  Effexor 19.5 mg, Remeron 9 mg.  As of 4/12/17:  Effexor 12.4 mg  Remeron 5.9 mg.

 

My intro: http://survivinganti...e-2#entry196679

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.


#150 uncomfortablynumb

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Posted 08 February 2016 - 04:25 PM

Hi SG, Thanks for sharing your crazy journey. So glad the reinstatement worked out for you and so fast. Looks like you hit rock bottom and are in such a better place now. I bet you will be back to work in no time. Things will just get better from there. You have endured a lot of the same symptoms as me. I don't think I gave reinstatement a real good chance. I messed up in desperation. I am not taking any drugs other than ativan once per week. The insomnia is the most killer thing. I am anxious and depressed but can still go out things and do things. I am not as social as I usually am and my brain is muddled. It is a mess. Some people are suggesting I still try and reinstate Effexor even now, some say Mirtaz. I am thinking marijuana. Hard to endure too many more sleepless nights. I wish I could wait it out.
10/2006 - Celexa 4 wks - not effective 10/2006 - Effexor - kicked in within 4 wks at 112mg dose. Over 3 yrs worked fairly consistently well but began having relapses of depression and anxiety. Upped dose to 150mg or 187mg and was fine. On Effexor, I was always taking workout energy supplements2009 - Effexor started pooping out and tried adding Abilify to no avail. Then tried Pristiq which also didn't help.2010 - Back on Effexor at 150mg. Surprisingly worked again, but less effective. Slowly started losing Effectiveness over 3 years.2013 - tried Zoloft, Nortriptyline, and Wellbutrin. Each separately for 4 weeks. Didn't give longer because they all were causing heart and other issues. 2014 - back to Effexor and it worked just to get me functioning. 04/2015 - off Effexor after a 2 month taper from 150mg. Was doing well for 3 months off meds but still taking pre-workout supps. 07/2015 - stopped taking my pre-workout energy supplement because I was abusing it and taking it for long periods. Stopped that cold turkey and quickly fell into depression and anxiety. 07/2015 - back on Effexor. From July to August slowly increased dose to 187mg and it didn't do anything. 09/2015 - began weaning off Effexor 37mg drops every wk. Then half of 37mg for a week to nothing on Oct. 16. Cue W/D symptoms 11/01/2015 - reinstated 37.5mg Effexor for a day and quit because it made me feel worse. Then 10 beads. Gave up. 12/01/2015 - Doc prescribed Remeron for severe insomnia. Took 15mg for 2 days and 7.5 for 4 days and stopped. Realized this was not a good long term solution for a withdrawal symptom.
Experiencing severe insomnia dizziness,headache,brain zaps. Severe anxiety and depression. Mind is mostly blank - difficulty thinking/concentrating. Hard to socialize. Poor long term memory. Depersonalization/unreal feeling. Emotional flatness. No interest or motivation.

#151 uncomfortablynumb

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Posted 13 March 2017 - 04:37 PM

Hi Everyone, I haven't updated my signature but for the last year I was on Remeron to help with the Effexor withdrawal. I was dying and desperate for sleep. It helped and I got back to full health, back working and socializing. Anhedonia and depersonalization melted away. Over the year, I weaned down from 15mg to under 3.75mg. When I got under that withdrawal hit full force. I should have got the liquid and gone super-slow. I have recently reinstated 15mg. Maybe too high. Got sleep the first night and nothing the next 3 days. Not sure if this is going to work. I am suffering horrible withdrawal -severe insomnia, anxiety/agoraphobia, depression, anhedonia, and depersonalization. I am also sensitive to light and sound. When I try to relax and fall asleep I get jerked awake so I am not sleeping. I feel like I can't recover from this mess. Maybe if I could sleep. Please help. Anyone who has experienced this and recovered.
10/2006 - Celexa 4 wks - not effective 10/2006 - Effexor - kicked in within 4 wks at 112mg dose. Over 3 yrs worked fairly consistently well but began having relapses of depression and anxiety. Upped dose to 150mg or 187mg and was fine. On Effexor, I was always taking workout energy supplements2009 - Effexor started pooping out and tried adding Abilify to no avail. Then tried Pristiq which also didn't help.2010 - Back on Effexor at 150mg. Surprisingly worked again, but less effective. Slowly started losing Effectiveness over 3 years.2013 - tried Zoloft, Nortriptyline, and Wellbutrin. Each separately for 4 weeks. Didn't give longer because they all were causing heart and other issues. 2014 - back to Effexor and it worked just to get me functioning. 04/2015 - off Effexor after a 2 month taper from 150mg. Was doing well for 3 months off meds but still taking pre-workout supps. 07/2015 - stopped taking my pre-workout energy supplement because I was abusing it and taking it for long periods. Stopped that cold turkey and quickly fell into depression and anxiety. 07/2015 - back on Effexor. From July to August slowly increased dose to 187mg and it didn't do anything. 09/2015 - began weaning off Effexor 37mg drops every wk. Then half of 37mg for a week to nothing on Oct. 16. Cue W/D symptoms 11/01/2015 - reinstated 37.5mg Effexor for a day and quit because it made me feel worse. Then 10 beads. Gave up. 12/01/2015 - Doc prescribed Remeron for severe insomnia. Took 15mg for 2 days and 7.5 for 4 days and stopped. Realized this was not a good long term solution for a withdrawal symptom.
Experiencing severe insomnia dizziness,headache,brain zaps. Severe anxiety and depression. Mind is mostly blank - difficulty thinking/concentrating. Hard to socialize. Poor long term memory. Depersonalization/unreal feeling. Emotional flatness. No interest or motivation.

#152 Altostrata

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Posted 14 March 2017 - 09:28 PM

UN, I joined your new post here to update your Intro topic. Please continue to update this topic, it will save us all from asking questions about your history.

 

It's been such a long time since you posted, there's a big gap in your history.

 

Since you were stable on a larger dosage of Remeron, have you tried updosing slightly, to 4mg or so?


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#153 uncomfortablynumb

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Posted 15 March 2017 - 07:14 AM

I listened to my doc and reinstated 15mg. Probably not the best idea. Not sleeping at all for days - completely wired and exhausted. Don't know to do now. Lower it? I am feeling very desperate.
10/2006 - Celexa 4 wks - not effective 10/2006 - Effexor - kicked in within 4 wks at 112mg dose. Over 3 yrs worked fairly consistently well but began having relapses of depression and anxiety. Upped dose to 150mg or 187mg and was fine. On Effexor, I was always taking workout energy supplements2009 - Effexor started pooping out and tried adding Abilify to no avail. Then tried Pristiq which also didn't help.2010 - Back on Effexor at 150mg. Surprisingly worked again, but less effective. Slowly started losing Effectiveness over 3 years.2013 - tried Zoloft, Nortriptyline, and Wellbutrin. Each separately for 4 weeks. Didn't give longer because they all were causing heart and other issues. 2014 - back to Effexor and it worked just to get me functioning. 04/2015 - off Effexor after a 2 month taper from 150mg. Was doing well for 3 months off meds but still taking pre-workout supps. 07/2015 - stopped taking my pre-workout energy supplement because I was abusing it and taking it for long periods. Stopped that cold turkey and quickly fell into depression and anxiety. 07/2015 - back on Effexor. From July to August slowly increased dose to 187mg and it didn't do anything. 09/2015 - began weaning off Effexor 37mg drops every wk. Then half of 37mg for a week to nothing on Oct. 16. Cue W/D symptoms 11/01/2015 - reinstated 37.5mg Effexor for a day and quit because it made me feel worse. Then 10 beads. Gave up. 12/01/2015 - Doc prescribed Remeron for severe insomnia. Took 15mg for 2 days and 7.5 for 4 days and stopped. Realized this was not a good long term solution for a withdrawal symptom.
Experiencing severe insomnia dizziness,headache,brain zaps. Severe anxiety and depression. Mind is mostly blank - difficulty thinking/concentrating. Hard to socialize. Poor long term memory. Depersonalization/unreal feeling. Emotional flatness. No interest or motivation.

#154 uncomfortablynumb

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Posted 16 March 2017 - 02:37 PM

I brought the dose down to 7.5mg. I have complete sleep deprivation. Is there anything I can do? Please help!
10/2006 - Celexa 4 wks - not effective 10/2006 - Effexor - kicked in within 4 wks at 112mg dose. Over 3 yrs worked fairly consistently well but began having relapses of depression and anxiety. Upped dose to 150mg or 187mg and was fine. On Effexor, I was always taking workout energy supplements2009 - Effexor started pooping out and tried adding Abilify to no avail. Then tried Pristiq which also didn't help.2010 - Back on Effexor at 150mg. Surprisingly worked again, but less effective. Slowly started losing Effectiveness over 3 years.2013 - tried Zoloft, Nortriptyline, and Wellbutrin. Each separately for 4 weeks. Didn't give longer because they all were causing heart and other issues. 2014 - back to Effexor and it worked just to get me functioning. 04/2015 - off Effexor after a 2 month taper from 150mg. Was doing well for 3 months off meds but still taking pre-workout supps. 07/2015 - stopped taking my pre-workout energy supplement because I was abusing it and taking it for long periods. Stopped that cold turkey and quickly fell into depression and anxiety. 07/2015 - back on Effexor. From July to August slowly increased dose to 187mg and it didn't do anything. 09/2015 - began weaning off Effexor 37mg drops every wk. Then half of 37mg for a week to nothing on Oct. 16. Cue W/D symptoms 11/01/2015 - reinstated 37.5mg Effexor for a day and quit because it made me feel worse. Then 10 beads. Gave up. 12/01/2015 - Doc prescribed Remeron for severe insomnia. Took 15mg for 2 days and 7.5 for 4 days and stopped. Realized this was not a good long term solution for a withdrawal symptom.
Experiencing severe insomnia dizziness,headache,brain zaps. Severe anxiety and depression. Mind is mostly blank - difficulty thinking/concentrating. Hard to socialize. Poor long term memory. Depersonalization/unreal feeling. Emotional flatness. No interest or motivation.

#155 ChessieCat

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Posted 16 March 2017 - 02:49 PM

From Post #51:

 

"I have recently reinstated 15mg."

 

When did you reinstate 15mg?  Having accurate information helps us to offer suggestions.


Podcasts:    Let's Talk Withdrawal

 

Antidepressants:  25 years - 1 unknown, Prozac (caused muscle weakness), Zoloft; Cipramil CTed (very sick for 2.5 wks soon after)

Pristiq:  50mg mid 2012, 100mg beg 2014 (mild Serotonin Toxicity)     Current:  Pristiq 25mg (from 21 April 2017)

 

Tapering history & graph

My website - includes my brief history + links to videos & information on the web

 

I've still got a way to go ... but I've already come a long way!!!

 

PLEASE NOTE:  I am not a medical professional.


#156 uncomfortablynumb

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Posted 16 March 2017 - 02:52 PM

15mg was reinstated March 11th.
10/2006 - Celexa 4 wks - not effective 10/2006 - Effexor - kicked in within 4 wks at 112mg dose. Over 3 yrs worked fairly consistently well but began having relapses of depression and anxiety. Upped dose to 150mg or 187mg and was fine. On Effexor, I was always taking workout energy supplements2009 - Effexor started pooping out and tried adding Abilify to no avail. Then tried Pristiq which also didn't help.2010 - Back on Effexor at 150mg. Surprisingly worked again, but less effective. Slowly started losing Effectiveness over 3 years.2013 - tried Zoloft, Nortriptyline, and Wellbutrin. Each separately for 4 weeks. Didn't give longer because they all were causing heart and other issues. 2014 - back to Effexor and it worked just to get me functioning. 04/2015 - off Effexor after a 2 month taper from 150mg. Was doing well for 3 months off meds but still taking pre-workout supps. 07/2015 - stopped taking my pre-workout energy supplement because I was abusing it and taking it for long periods. Stopped that cold turkey and quickly fell into depression and anxiety. 07/2015 - back on Effexor. From July to August slowly increased dose to 187mg and it didn't do anything. 09/2015 - began weaning off Effexor 37mg drops every wk. Then half of 37mg for a week to nothing on Oct. 16. Cue W/D symptoms 11/01/2015 - reinstated 37.5mg Effexor for a day and quit because it made me feel worse. Then 10 beads. Gave up. 12/01/2015 - Doc prescribed Remeron for severe insomnia. Took 15mg for 2 days and 7.5 for 4 days and stopped. Realized this was not a good long term solution for a withdrawal symptom.
Experiencing severe insomnia dizziness,headache,brain zaps. Severe anxiety and depression. Mind is mostly blank - difficulty thinking/concentrating. Hard to socialize. Poor long term memory. Depersonalization/unreal feeling. Emotional flatness. No interest or motivation.

#157 ChessieCat

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Posted 16 March 2017 - 03:06 PM

Thank you.  I'll ask the other mods for their thoughts.


Podcasts:    Let's Talk Withdrawal

 

Antidepressants:  25 years - 1 unknown, Prozac (caused muscle weakness), Zoloft; Cipramil CTed (very sick for 2.5 wks soon after)

Pristiq:  50mg mid 2012, 100mg beg 2014 (mild Serotonin Toxicity)     Current:  Pristiq 25mg (from 21 April 2017)

 

Tapering history & graph

My website - includes my brief history + links to videos & information on the web

 

I've still got a way to go ... but I've already come a long way!!!

 

PLEASE NOTE:  I am not a medical professional.


#158 JanCarol

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Posted 17 March 2017 - 05:44 AM

Hey UN - 

 

So you went to 15 on March 11, but then went back to 7.5 mg on Mar 17?

 

And your last change before that was - in 2015?  Or have you had other changes?  (I see an attempt at melatonin on this page - 1.5 mg 9-Feb.  Add a month to every time you make a change in dose, supplements, or supplement dose - to see how you long it takes for you to settle down from a change - any change.

 

The best way to be stable is to pick a dose and stay there. 

 

You will have to decide which was less uncomfortable:  15 or 7.5 and then stay there.  Stick to it like flypaper, same dose, same time every day (I'm guessing you are taking it in the evening?)

 

Research here for sleep hygiene and other aids:

Important Topics about Symptoms Including Sleep Problems

 

Please update your signature to show us what changes you have had since 2015?  Thank you!

 

I hope you see the sun today!


"Easy, easy - just go easy and you'll finish." - Hawaiian Kapuna

 

Holding is hard work, holding is a blessing. Give your brain time to heal before you try again.

 

My suggestions are not medical advice, you are in charge of your own medical choices.

 

A lifetime of being prescribed antidepressants that caused problems (30 years in total). At age 35 flipped to "bipolar," but was not diagnosed for 5 years. Started my journey in Midwest United States. Crossed the Pacific for love and hope; currently living in Australia.   CT Seroquel 25 mg some time in 2013.   Tapered Reboxetine 4 mg Oct 2013 to Sept 2014 = GONE (3 years on Reboxetine).     Tapered Lithium 900 to 475 MG (alternating with the SNRI) Jan 2014 - Nov 2014, tapered Lithium 475 mg Jan 2015 -  Feb 2016 = GONE (10 years  on Lithium).  Many mistakes in dry cutting dosages were made.

 

Currently Lithium Orotate 1.67 mg only.  I will re-evaluate this supplement in 2017.

 

I have been psych drug FREE since 1 Feb 2016!


#159 uncomfortablynumb

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Posted 17 March 2017 - 06:33 AM

Thanks for messaging and your advice. In February I also reinstated the 15mg of mirt for a week and then down to 7.5mg for another week. At that point I was getting 2-3hrs of sleep. I should have settled with that. Next was trazodone for 2 days. That brings me to where I am now. For supplements I only take fish oil and magnesium. Really scared now that I have ruined my ability to sleep. The wiredness and muscle twitching laying down is concerning.
10/2006 - Celexa 4 wks - not effective 10/2006 - Effexor - kicked in within 4 wks at 112mg dose. Over 3 yrs worked fairly consistently well but began having relapses of depression and anxiety. Upped dose to 150mg or 187mg and was fine. On Effexor, I was always taking workout energy supplements2009 - Effexor started pooping out and tried adding Abilify to no avail. Then tried Pristiq which also didn't help.2010 - Back on Effexor at 150mg. Surprisingly worked again, but less effective. Slowly started losing Effectiveness over 3 years.2013 - tried Zoloft, Nortriptyline, and Wellbutrin. Each separately for 4 weeks. Didn't give longer because they all were causing heart and other issues. 2014 - back to Effexor and it worked just to get me functioning. 04/2015 - off Effexor after a 2 month taper from 150mg. Was doing well for 3 months off meds but still taking pre-workout supps. 07/2015 - stopped taking my pre-workout energy supplement because I was abusing it and taking it for long periods. Stopped that cold turkey and quickly fell into depression and anxiety. 07/2015 - back on Effexor. From July to August slowly increased dose to 187mg and it didn't do anything. 09/2015 - began weaning off Effexor 37mg drops every wk. Then half of 37mg for a week to nothing on Oct. 16. Cue W/D symptoms 11/01/2015 - reinstated 37.5mg Effexor for a day and quit because it made me feel worse. Then 10 beads. Gave up. 12/01/2015 - Doc prescribed Remeron for severe insomnia. Took 15mg for 2 days and 7.5 for 4 days and stopped. Realized this was not a good long term solution for a withdrawal symptom.
Experiencing severe insomnia dizziness,headache,brain zaps. Severe anxiety and depression. Mind is mostly blank - difficulty thinking/concentrating. Hard to socialize. Poor long term memory. Depersonalization/unreal feeling. Emotional flatness. No interest or motivation.

#160 uncomfortablynumb

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Posted 17 March 2017 - 04:50 PM

Is there anything I can do? The sleep deprivation is torture and has taken its toll on my immune system and testosterone and who knows what else.
10/2006 - Celexa 4 wks - not effective 10/2006 - Effexor - kicked in within 4 wks at 112mg dose. Over 3 yrs worked fairly consistently well but began having relapses of depression and anxiety. Upped dose to 150mg or 187mg and was fine. On Effexor, I was always taking workout energy supplements2009 - Effexor started pooping out and tried adding Abilify to no avail. Then tried Pristiq which also didn't help.2010 - Back on Effexor at 150mg. Surprisingly worked again, but less effective. Slowly started losing Effectiveness over 3 years.2013 - tried Zoloft, Nortriptyline, and Wellbutrin. Each separately for 4 weeks. Didn't give longer because they all were causing heart and other issues. 2014 - back to Effexor and it worked just to get me functioning. 04/2015 - off Effexor after a 2 month taper from 150mg. Was doing well for 3 months off meds but still taking pre-workout supps. 07/2015 - stopped taking my pre-workout energy supplement because I was abusing it and taking it for long periods. Stopped that cold turkey and quickly fell into depression and anxiety. 07/2015 - back on Effexor. From July to August slowly increased dose to 187mg and it didn't do anything. 09/2015 - began weaning off Effexor 37mg drops every wk. Then half of 37mg for a week to nothing on Oct. 16. Cue W/D symptoms 11/01/2015 - reinstated 37.5mg Effexor for a day and quit because it made me feel worse. Then 10 beads. Gave up. 12/01/2015 - Doc prescribed Remeron for severe insomnia. Took 15mg for 2 days and 7.5 for 4 days and stopped. Realized this was not a good long term solution for a withdrawal symptom.
Experiencing severe insomnia dizziness,headache,brain zaps. Severe anxiety and depression. Mind is mostly blank - difficulty thinking/concentrating. Hard to socialize. Poor long term memory. Depersonalization/unreal feeling. Emotional flatness. No interest or motivation.

#161 Altostrata

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Posted 17 March 2017 - 09:57 PM

Maybe 7.5mg is too much.

 

UN, I joined your new post here to update your Intro topic. Please continue to update this topic, it will save us all from asking questions about your history.

 

It's been such a long time since you posted, there's a big gap in your history.

 

Since you were stable on a larger dosage of Remeron, have you tried updosing slightly, to 4mg or so?


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

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#162 JanCarol

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Posted 18 March 2017 - 07:33 AM

Trazodone is another bounce.

 

It may seem too hard, but you need to stop bouncing.

 

Need to let your brain and nervous system settle.

 

Please update your signature to include the past 2 years.


"Easy, easy - just go easy and you'll finish." - Hawaiian Kapuna

 

Holding is hard work, holding is a blessing. Give your brain time to heal before you try again.

 

My suggestions are not medical advice, you are in charge of your own medical choices.

 

A lifetime of being prescribed antidepressants that caused problems (30 years in total). At age 35 flipped to "bipolar," but was not diagnosed for 5 years. Started my journey in Midwest United States. Crossed the Pacific for love and hope; currently living in Australia.   CT Seroquel 25 mg some time in 2013.   Tapered Reboxetine 4 mg Oct 2013 to Sept 2014 = GONE (3 years on Reboxetine).     Tapered Lithium 900 to 475 MG (alternating with the SNRI) Jan 2014 - Nov 2014, tapered Lithium 475 mg Jan 2015 -  Feb 2016 = GONE (10 years  on Lithium).  Many mistakes in dry cutting dosages were made.

 

Currently Lithium Orotate 1.67 mg only.  I will re-evaluate this supplement in 2017.

 

I have been psych drug FREE since 1 Feb 2016!


#163 uncomfortablynumb

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Posted 20 March 2017 - 02:33 PM

I don't know if this insomnia will kill me. I don't have the sensation of being tired. Just wired and sick. I am scared.
10/2006 - Celexa 4 wks - not effective 10/2006 - Effexor - kicked in within 4 wks at 112mg dose. Over 3 yrs worked fairly consistently well but began having relapses of depression and anxiety. Upped dose to 150mg or 187mg and was fine. On Effexor, I was always taking workout energy supplements2009 - Effexor started pooping out and tried adding Abilify to no avail. Then tried Pristiq which also didn't help.2010 - Back on Effexor at 150mg. Surprisingly worked again, but less effective. Slowly started losing Effectiveness over 3 years.2013 - tried Zoloft, Nortriptyline, and Wellbutrin. Each separately for 4 weeks. Didn't give longer because they all were causing heart and other issues. 2014 - back to Effexor and it worked just to get me functioning. 04/2015 - off Effexor after a 2 month taper from 150mg. Was doing well for 3 months off meds but still taking pre-workout supps. 07/2015 - stopped taking my pre-workout energy supplement because I was abusing it and taking it for long periods. Stopped that cold turkey and quickly fell into depression and anxiety. 07/2015 - back on Effexor. From July to August slowly increased dose to 187mg and it didn't do anything. 09/2015 - began weaning off Effexor 37mg drops every wk. Then half of 37mg for a week to nothing on Oct. 16. Cue W/D symptoms 11/01/2015 - reinstated 37.5mg Effexor for a day and quit because it made me feel worse. Then 10 beads. Gave up. 12/01/2015 - Doc prescribed Remeron for severe insomnia. Took 15mg for 2 days and 7.5 for 4 days and stopped. Realized this was not a good long term solution for a withdrawal symptom.
Experiencing severe insomnia dizziness,headache,brain zaps. Severe anxiety and depression. Mind is mostly blank - difficulty thinking/concentrating. Hard to socialize. Poor long term memory. Depersonalization/unreal feeling. Emotional flatness. No interest or motivation.

#164 scallywag

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Posted 20 March 2017 - 05:47 PM

Insomnia makes functioning difficult but it won't kill you.  Do what you can to get rest -- quiet time where you lie as still as possible with your eyes closed.  You may want to search youtube for meditations to help sleep, rest, and/or relaxation to play at low volume during your rest periods.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.
1997-1999 Effexor; 2002-2005 Effexor XR 37.5 mg linear taper, dropping same #beads/week with bad results
Cymbalta (brand name), 60 mg 2012 - 2015; 20 mg to 7 mg in 2016, exact doses and dates in this post;
2017: 6.3 (58 beads) Feb. 1; 5.6 mg (52) Feb. 22; 5.4 mg (50) Mar. 15; 5.1 mg (47) Mar. 25; 4.9 mg (45) Apr. 5;
Current dose: 4.5 mg (42) 2017-Apr-14
+ Supplements: fish oil (1500 mg EPA/500 mg DHA), Vitamins: D3, K2, C; Minerals: Mg, Se, Cr, I, V
scallywag's Introduction
Online spreadsheet for dose taper calculations and nz11's THE WORKS spreadsheet


#165 uncomfortablynumb

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Posted 20 March 2017 - 06:24 PM

Thanks for your response. Well, I am at the non-functional state. Has anyone experienced many days without sleep in a row? Can't fall asleep and I get these twitches and jolts when I try to relax and drift off. I wonder at what point I will just black-out.
10/2006 - Celexa 4 wks - not effective 10/2006 - Effexor - kicked in within 4 wks at 112mg dose. Over 3 yrs worked fairly consistently well but began having relapses of depression and anxiety. Upped dose to 150mg or 187mg and was fine. On Effexor, I was always taking workout energy supplements2009 - Effexor started pooping out and tried adding Abilify to no avail. Then tried Pristiq which also didn't help.2010 - Back on Effexor at 150mg. Surprisingly worked again, but less effective. Slowly started losing Effectiveness over 3 years.2013 - tried Zoloft, Nortriptyline, and Wellbutrin. Each separately for 4 weeks. Didn't give longer because they all were causing heart and other issues. 2014 - back to Effexor and it worked just to get me functioning. 04/2015 - off Effexor after a 2 month taper from 150mg. Was doing well for 3 months off meds but still taking pre-workout supps. 07/2015 - stopped taking my pre-workout energy supplement because I was abusing it and taking it for long periods. Stopped that cold turkey and quickly fell into depression and anxiety. 07/2015 - back on Effexor. From July to August slowly increased dose to 187mg and it didn't do anything. 09/2015 - began weaning off Effexor 37mg drops every wk. Then half of 37mg for a week to nothing on Oct. 16. Cue W/D symptoms 11/01/2015 - reinstated 37.5mg Effexor for a day and quit because it made me feel worse. Then 10 beads. Gave up. 12/01/2015 - Doc prescribed Remeron for severe insomnia. Took 15mg for 2 days and 7.5 for 4 days and stopped. Realized this was not a good long term solution for a withdrawal symptom.
Experiencing severe insomnia dizziness,headache,brain zaps. Severe anxiety and depression. Mind is mostly blank - difficulty thinking/concentrating. Hard to socialize. Poor long term memory. Depersonalization/unreal feeling. Emotional flatness. No interest or motivation.