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TILT Includes fibro and multiple chemical sensitivity


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#1 btdt

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Posted 16 February 2016 - 04:27 AM

So today I found this link 

 

Titled 

Toxicant Induced Loss of Tolerance TILT - C Miller, MD, PhD
Which can cause all sorts of things autism add depression and as the good doc says can be dx as many different things by many different doctors. 
Caused by a toxic reaction to a chemical which likely has a genetic component resulting in reactions causing displays of mood and thought neurological conditions including fibro. and multiple chemical sensitivities.  So now we have it all in one ball of wax if the good doctor is correct. It is an interesting idea the parts of the brain damaged by the chemical exposure are the same areas of the brain they look at in depression ect...hypo campus limbic  blah blah sorry memory fails me. 
So fibro pain mood for me was mostly pain pain pain... mcs... well self explanatory. 
The part that is even more interesting to me is she says it can be healed... if all these things are avoided and that may mean dietary changes very clean air and water... avoiding chemicals including perfumes ect... most personal care products and cleaning products have chemicals they do not need...or that we cannot afford.  Did I mention tooth paste... I can't tolerate fluoride since there may well be a genetic component to this and I think there is we have to think of our kids too...if you have any. 
I looked for an update to her work and did not find anything if anyone most suited to google search has better luck please add any links to this thread.  Thanks. 
ps if you don't know me I have long since blamed my fibro on taking prozac years ago... and you can read about it other places on this site if you like ... it surely makes more sense the more I learn and the more dx I get ...or more fallout. 
Apparently there is an ebook at the end if you would rather read about it. 
peace all
 
ps don't shoot the messenger.  :o

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#2 btdt

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Posted 16 February 2016 - 06:04 AM

drugs that cause cognitive impairment 

this needs to be put with this above post so folks know what to really stay away from 

http://www.richardsf..._impairment.pdf

 

drugs they use to put you out for surgery are mentioned in the video above


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#3 btdt

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Posted 23 February 2016 - 07:51 AM

http://survivinganti...tigue-syndrome/

Chronic Fatigue Syndrome
 
 
Auto Immune diseases triggered by SSRI Withdrawal

http://survivinganti...sri-withdrawal/

 

Scientific Study Links Anti-depressants In Drinking Water To ...
www.infowars.com/scientific-study-links-anti-depressants-in-drinking-w...
  •  
  •  

Jun 7, 2012 - Psychoactive drugs in our drinking water could be triggering autismnotes ... found that just traces of selective serotonin uptake inhibitors (SSRIs) such as... found in the drinking supply may be a cause of autism in humans.

 

 

One day all of these may prove to be the same monkey in different outfits


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#4 btdt

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Posted 03 March 2016 - 05:01 AM

I wonder if drugs in the drinking water play any part in protracted withdrawal... do people who have well water heal... 

do they heal faster?  


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#5 btdt

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Posted 03 March 2016 - 05:14 AM

The book...

http://drclaudiamiller.com/

 

Exposures 

http://drclaudiamill...ions-exposures/

 

 

 

 

" a new class of diseases, involving a two-step disease process not previously recognized"

 

It is not feeling so new to me dx with fibro in the early 1990"s ... bet those of us in protracted withdrawal are actually in the second stage of this two step disease process... the state that does not end. 

11. Do you see patients?
I no longer see patients. I am dedicated to advancing research related to Toxicant-induced Loss of Tolerance (TILT). TILT represents a new class of diseases, involving a two-step disease process not previously recognized. In effect, we are at the “germ theory” stage in terms of our understanding of TILT. I feel I can best help individual patients by focusing my efforts on research and writing. Although I no longer consult on individual cases, patients frequently find it helpful to take their QEESI results and my publications to their personal doctors.
Back to Questions


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#6 btdt

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Posted 07 March 2016 - 06:37 PM

http://drclaudiamill...s-of-tolerance/

"How the settlement landed so far off the mark is anyone’s guess. One $14.4 million grant will send mental health counselors to the Gulf Coast" "And yet, not one dime has been allocated to study how the toxic exposures  resulting from this disaster have rendered thousands of workers and residents chemically sensitive and suffering from the same disabling multi-system symptoms that afflict the hundreds of thousands of American soldiers who suffer from what has become known as Gulf War Syndrome."  

dah lobbiest earn their pay

Gulf War Syndrome Comes to the Gulf of Mexico

July 20, 2012, 5:32 pm

Millions of dollars from the BP Claims Fund are being poured into healthcare efforts in the wake of the  Deepwater Horizon disaster “to expand access to healthcare in underserved communities,” for “behavioral and mental health needs,” to “train community health care workers on peer listening, community resiliency and other related issues,” and to “expand and improve environmental health expertise, capacity and literacy.”

And yet, not one dime has been allocated to study how the toxic exposures  resulting from this disaster have rendered thousands of workers and residents chemically sensitive and suffering from the same disabling multi-system symptoms that afflict the hundreds of thousands of American soldiers who suffer from what has become known as Gulf War Syndrome.

What we are witnessing, in fact, is the emergence of an entirely new disease mechanism that has grown out of the post-World War II petrochemical age and rendered millions of Americans who have suffered toxic exposures chronically ill. And the only way to help victims of toxic exposures and those in the future is to go after this mechanism.

How the settlement landed so far off the mark is anyone’s guess. One $14.4 million grant will send mental health counselors to the Gulf Coast.

People along the Gulf Coast are reacting to this news of misdirected largesse. As a reader of the Mobile (Ala.) Press-Register posted on the newspaper’s website, “Who will contain the money spill?”

Related link: My earlier message “To Gulf Oil Spill Responders: What You and Your Doctors Need to Know About TILT.”

Responders to the Deepwater Horizon spill, like the clean-up workers in the Exxon Valdez accident 20 years ago, have long been reporting chronic health problems associated with TILT, including multi-system symptoms (fatigue, sleep problems, headaches, digestive difficulties, and problems with memory and concentration) as well as new intolerances for everyday exposures that never bothered them before.

An article from the Huffington Post in March 2012 describes how doctors along the Gulf Coast are routinely treating clean-up workers and residents for chemical exposure and other problems that they blame on the spill. The article includes statements from a physician who uses the QEESI diagnostic questionnaire, Michael Robichaux, an otolaryngologist in Raceland, La., outside New Orleans.

Dr. Robichaux said he has treated 50 people for a range of health problems that he believes were caused by exposure to chemicals from the spill. “The illnesses are very real, and the people who are ill are apparently people who have sensitivities to these substances that not all of us are sensitive to,” he told the Huffington Post.

Patients suffering exposure symptoms may feel dizzy or nauseated around engine exhaust, cleaning chemicals, fragrances, or ill after meals, eating certain foods or even drinking one beer or glass of wine. These new intolerances are the hallmark symptom of a disease process called “TILT,” or “Toxicant-induced Loss of Tolerance.” We know that even so-called “safe” levels of exposure to toxic petroleum-based chemicals like those in the Gulf can initiate TILT. Once TILT develops, it is very difficult to treat, but TILT can be prevented.

To find out whether you may be susceptible to TILT or to track your symptoms, take the QEESI — a validated and published questionnaire I developed. You can download the QEESI at no charge under the “Publications & Presentations” tab.


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#7 UnfoldingSky

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Posted 07 March 2016 - 06:56 PM

I wonder if drugs in the drinking water play any part in protracted withdrawal... do people who have well water heal... 

do they heal faster?  

 

I've long wondered that as well.

 

I mean, realistically, if some of us react badly even to small doses of drugs, or taking minute amounts of herbs (which tend to be infinitely safer on the whole than drugs do) or even some foods, then, it certainly seems possible that the slew of pharma products in the water could be making us worse. Of course the concentrations differ though, so who knows.

 

I used to at times get well water in early withdrawal, I am not sure if it made a big difference but I felt better about drinking it.  The water where I am tends to be overly chlorinated and smells like a swimming pool.  Yum.

 

I also tried boiled rain water for a bit, you wouldn't believe how hard it is though...I came out feeling thirstier than when I started. 
 


Partly recovered from AD withdrawal/reactions as well as issues with other psych drugs.  Also, I am not a medical professional and nothing I say is a medical opinion or meant to be medical advice, please seek a competent and trusted medical professional to consult for all medical decisions. Also due to the withdrawal/reactions I have had I may at times have cognitive problems so please keep this in mind when reading my posts (also please note, these issues are improving as I recover).

 


#8 btdt

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Posted 07 March 2016 - 08:18 PM

I have tried a few water filter systems in jug form the brita and the zero back to the brita now not sure it does much but makes the water drinkable


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#9 UnfoldingSky

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Posted 08 March 2016 - 07:54 PM

I used to have a Brita too, I didn't use it during withdrawal though.  I do wonder too if it even does anything..I'm skeptical that it would remove drugs at least.


Partly recovered from AD withdrawal/reactions as well as issues with other psych drugs.  Also, I am not a medical professional and nothing I say is a medical opinion or meant to be medical advice, please seek a competent and trusted medical professional to consult for all medical decisions. Also due to the withdrawal/reactions I have had I may at times have cognitive problems so please keep this in mind when reading my posts (also please note, these issues are improving as I recover).

 


#10 ang

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Posted 22 March 2016 - 03:57 AM

 

So today I found this link Toxicant Induced Loss of Tolerance TILT - C Miller, MD, PhD

 
Which can cause all sorts of things autism add depression and as the good doc says can be dx as many different things by many different doctors. 
Caused by a toxic reaction to a chemical which likely has a genetic component resulting in reactions causing displays of mood and thought neurological conditions including fibro. and multiple chemical sensitivities.  So now we have it all in one ball of wax if the good doctor is correct. It is an interesting idea the parts of the brain damaged by the chemical exposure are the same areas of the brain they look at in depression ect...hypo campus limbic  blah blah sorry memory fails me. 
So fibro pain mood for me was mostly pain pain pain... mcs... well self explanatory. 
The part that is even more interesting to me is she says it can be healed... if all these things are avoided and that may mean dietary changes very clean air and water... avoiding chemicals including perfumes ect... most personal care products and cleaning products have chemicals they do not need...or that we cannot afford.  Did I mention tooth paste... I can't tolerate fluoride since there may well be a genetic component to this and I think there is we have to think of our kids too...if you have any. 
I looked for an update to her work and did not find anything if anyone most suited to google search has better luck please add any links to this thread.  Thanks. 
ps if you don't know me I have long since blamed my fibro on taking prozac years ago... and you can read about it other places on this site if you like ... it surely makes more sense the more I learn and the more dx I get ...or more fallout. 
Apparently there is an ebook at the end if you would rather read about it. 
peace all
 
ps don't shoot the messenger.  :o

 

i AM STUDYING FLUORIDE,  INFORMATION WELCOME!!!!!!!!!


1992 Dothiepin 375mg 8 weeks, exhaustion/depression.  Serotonin syndrome, oh yes!  seizures . Fell pregnant, 3rd baby, Nitrous Oxide, 3 weeks mental hospital pp psychosis. zoloft tegretol.

Feb 1996 ct tegretol, tapered Zoloft 8 weeks. as (unexpectedly)  pregnant. Steven died after 3 days.(Zolft HLHS baby).  98 had run in with Paxil, 2 tablets, 3 weeks taper, survived.
2005..menopause? exhausted again. Zyprexa, mad in three days, fallout....  Seroquel, Effexor, tegretol,   and 8 years of self destruction. Failed taper.
Damn 1/4 valium... nuts again! .fallout, zoloft 100mg  seroquol 400mg mirtazapine 45 mg  tegretol 400mg.  Mid 14 3 month taper. Nov 14 CRASH.
Mid 15 ....   75mg  seroquel,  3 x 1800mg SJW  2 week window end of December followed by 6 week wave
5/2 68mg seroquel, 2.5 x 1800mg SJW::::20/2 61mg seroquel, 2.5 x  SJW::: 26/2 54mg seroquel, 2 x SJW::::21/3 43mg seroquel, 1 x 2700SJW :::: 23/4 36mg seroquel 1 x 1800 SJW
15/5 33mg seroquel, 1 x SJW::::   28/5 30mg seroquel, 1 x SJW::::;  18/6 25mg seroquel 1/2 SJW::::, 11/7 21mg seroquel 1/2 SJW::, 26/7 18mg seroquel 1/2 SJW:::, 9/8 12mg seroquel :::, 16/8 6mg seroquel ;;;;, 12/9 0 jump.

23/9  3mg.....,  27/9 0mg.  Reinstated, 6mg, then 12mg.............  LIGHTBULB MOMENT,  I have  MTHFR 2x mutations.  CFS and issues with MOULD in my home. So I left home, and working 150km away during week, loving it.

Oh was hard, panic attacks first week, gone now, along with the mould issues.


#11 btdt

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Posted 22 March 2016 - 09:40 AM

I know some places have taken it out of the water systems as they deemed it unsafe. 


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#12 btdt

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Posted 17 May 2016 - 08:19 PM

The beginning of this entire idea starts here

 

http://survivinganti...persensitivity/

 

so if you new to this go to that thread first then come back and read this ... or do as you please cause you will anyway... I do. 

 

 

Treatment Effectiveness According to MCS Sufferers

As mentioned previously, Pamela Reed Gibson PhD asked 917 MCS patients to complete surveys in which they rated the effectiveness of treatments they had tried. The list of treatments the participants had tried was extensive and included interventions that would be classed as conventional and those that would be referred to as alternative.

Some of the most effective treatments based on the results of this survey were:
 

  1. Chemical avoidance/chemical-free living space
  2. Charcoal/carbon filter facemask
  3. Air purifier
  4. Personal oxygen for use after exposures
  5. Sauna Therapy
  6. Intravenous magnesium
  7. Vitamin C
  8. DHEA & thyroid hormone replacement
  9. Herbal medicines
  10. Colonics & liver flushes
  11. Meditation
  12. Acupressure
  13. Reflexology
  14. Chiropractic
  15. Psychotherapy to help cope with MCS


As a group, prescription medications faired worst in the survey although some of the alternative therapies were also deemed of little help.

The complete results of the survey are available as an appendix in Pamela Reed Gibson's excellent bookMultiple Chemical Sensitivity: A Survival Guide.


The Allergy Connection

As we currently understand it, MCS is not an allergy. An allergy is an immune reaction involving the production of IgE antibodies that attack harmless substances such as pollen and animal dander, triggering symptoms that typically include itchy, watery eyes, sneezing and nasal congestion. MCS is not primarily the result of such an immune reaction but involves neurological hypersensitivity and potentially complex systemic pathophysiological changes as outlined by Prof. Pall and others. That said, inflammatory cytokines are implicated in Pall's NO ONOO hypothesis and there is some evidence that mast cell activation (the cells that release histamine in an IgE-mediated allergic reaction) is involved in MCS11.

It is also common for an individual to suffer from both MCS and classical allergies and each is likely to compound the symptoms of the other so it only makes sense to treat the allergies as well if relief from MCS is to be achieved. Some common treatments for allergies, both conventional and laternative, include:
 


Ultimately managing and treating MCS requires much trial and error and the help of an experienced environmental medicine doctor.


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#13 btdt

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Posted 17 May 2016 - 08:24 PM

New clothes washing system that is working for me... no more detergents Dr. Bonnars soap baby formula I use about 1/3 cup per load with 1/4 cup of epsom salts supposedly acts as a fabric softener ...some clothes still have static I can live with that... some things that had been looking not so white came white.. interesting. 

I still hate sleeping any place that uses detergents as I can't stand the smell .. hate hotel towels yucky

 

the idea about was found at 

colorfulcanary.com

 

A site owned by a MCS Canadian


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#14 btdt

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Posted 17 May 2016 - 08:29 PM

Detoxification Support

It has been demonstrated that people with self-reported sensitivity to chemicals (read: "undiagnosed MCS sufferers") are more susceptible to the effects of chemical exposures than healthy individuals due to variations in genes of great importance in the detoxification of xenobiotic substances1. One study found that individuals known as 'slow acetylators' are more likely to be chemically sensitive - acetylation is one of several important chemical reactions by which toxic compounds are inactivated and excreted by the body1. The same study found gene variants that reduced the activity of glutathione, considered one of the most important detoxification and antioxidant molecules in the body, were also at increased risk of chemical sensitivity. With this in mind nutritional interventions often aim to support these detoxification pathways by supplying the required nutrients; N-Acetyl-Cysteine2 and alpha lipoic acid3 have been shown to effectively raise glutathione levels for example, as has the herb milk thistle (silymarin marianum)4.    

Another approach to detoxification using nutritional medicine takes things further and is designed to restore health to the cellular membranes so that every cell in the body becomes more efficient at detoxifying itself of toxic substances, both those from the environment such as drugs and pollutants and those generated in larger than normal amounts by the body itself due to the state of illness. This approach has been developed by Patricia Kane PhD and colleagues. The crux of the proposed protocol is the use of a fatty substance known as phosphatidylcholine (PC) in large dosages (both orally and intravenously). PC makes up a large proportion of a healthy cell membrane so the idea is that introducing large amounts of pure PC will replace the PC damaged by toxins and currently comprising the cell membranes, thus restoring cellular health and detoxification efficiency. The hoped for end result then is that total body toxic load is reduced which should aid in recovery from MCS. There are no published studies to support this theory but plenty of anecdotal reports from MCS patients on this website and around the internet. Learn more in The Detoxx Book and on our dedicated page here.

The Martin Pall Protocol

Martin Pall is Professor Emeritus of Biochemistry and Basic Medical Sciences at Washington State University and Research Director of The Tenth Paradigm Research Group. He has focused his research efforts on multiple chemical sensitivity, chronic fatigue syndrome, fibromyalgia and other interconnected multi-system illnesses for a number of years and developed arguably the most complete theory for their pathophysiology. His basic hypothesis states that an initial stressor of some kind (e.g. acute pesticide exposure, viral infection, physical trauma etc) initiate a response in the body that while protective and helpful in the short-term, becomes pathological in the long-term and leads to symptoms and illness. This he proposes is what happens in MCS, the reaction to the stressor never gets switched off and the resulting biochemical dysfunction causes and perpetuates the illness. The dysfunction centres around altered nitric oxide (NO) metabolism which has many consequences involving the production of very damaging reactive molecules (oxidative and nitrosative stress) like peroxynitrite, which in turn trigger production of inflammatory immune chemicals called cytokines; some of these being interleukin-1b (IL-1b), IL-6, tumor necrosis factor-alpha (TNF-a) and interferon gamma (IFN-g). The vicious cycle is perpetuated since these inflammatory cytokines induce the production of yet more NO. Professor Pall refers to his theory as NO ONOO (NO for nitric oxide and ONOO- being the chemical formula for peroxynitrite).

Professor Pall proposes that since the NO ONOO cycle is perpetuated by reactive oxygen species (ROS), also known as free radicals, along with inflammatory immune chemicals, it might be interrupted using nutritional supplements that are potent antioxidants and anti-inflammatory agents. The hope being that this would also lead to symptom resolution and recovery from MCS. These nutrients include vitamin C, vitamin B12, folic acid, coenzyme Q10, vitamin E (as natural tocopherols) and various antioxidant plant compounds such as bioflavonoids. More on the specific nutrients recommend by Pall here.  

Dr. Grace Ziem

Grace Ziem MD has worked extensively with patients suffering from MCS and chemical injury in her medical practice and has worked closely with Prof. Pall to develop a nutrient-based treatment protocol that is very close to Pall's own recommendations. Please visit Dr. Ziem's website for further details of her MCS treatment protocol - http://www.chemicali...tment_ingr.html

DHEA

This adrenal hormone is included here in the nutrient therapy section as it is available (in the US at least) as an over-the-counter nutritional supplement. DHEA is the most abundant hormone produced by the adrenal glands but its role remains unclear - it appears to have many functions. What is known is that is a neurosteroid i.e. a steroid hormone that acts on the brain and CNS. Importantly, it modulates the effects of the neurotransmitters N-methyl-D-aspartate (NMDA) and gamma-aminobutyric acid (GABA) in the limbic system (emotional and stress centre of the brain5. This could be important in the treatment of MCS since studies have shown hypersensitivity of certain brain regions like the limbic system with corresponding excessive neural activity when sufferers are exposed to a chemical to which they have become sensitised6. This also fits with Prof. Palls NO ONOO theory as the cycle of dysfunction proposed includes chronic dysfunction of NMDA activity. In a survey of 917 MCS patients Pamela Reed Gibson PhD asked them to rate the effectiveness of various treatments they had tried, DHEA faired well with roughly 30% of those who had tried it finding it to be either 'somewhat' or 'very' helpful7. Other nutrients that faired as well or better in this survey are included in Prof. Pall's and Dr. Ziem's recommendations.

  

 

 


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#15 btdt

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Posted 17 May 2016 - 09:29 PM

Multiple Chemical Sensitivites

We have included a section for environmental illness as many individuals with M.E. / CFS, experience a beginning or an increase of environmental and food sensitivities.

Reported Symptoms and Syndromes

Skin: Itching, burning, flushing, warmth, coldness, tingling, sweating behind the neck, etc. hives, blisters, blotches, red spots, "pimples".

Ear, nose & throat: Nasal congestion, sneezing, nasal itching, runny nose, postnasal drip. Sore, dry, or tickling throat, clearing throat, itching palate, hoarseness, hacking cough. Fullness ringing, or popping of ears, earache, intermittent deafness, dizziness, imbalance.

Eyes: Blurring of vision, pain in eyes, crossing of eyes, glare hurts eyes; eyelids twitching, drooping, or swollen; redness and swelling of inner angle of lower lid.

Respiratory: Shortness of breath, wheeze, cough, mucous formation in bronchial tubes.

Cardiovascular: Pounding heart, increased pulse rate, skipped beats, flushing, pallor, warm, cold, tingling, redness or blueness of hands, faintness, precordial pain.

Gastrointestinal: Dryness of mouth, increased salivation, canker sores, stinging tongue, burping, retasting, heartburn, indigestion, nausea, vomiting, difficulty in swallowing, rumbling in abdomen, abdominal pain, cramps, diarrhea, itching or burning of rectum.

Genitourinary: Frequent, urgent or painful urination; inability to control bladder; vaginal itching or discharge.

Muscular: Fatigue, generalized muscular weakness, muscle and joint pain, stiffness, soreness, chest pain, backache, neck and muscle spasm, generalized spasticity.

Nervous System: Headache, migraine, compulsively sleepy, drowsy, groggy, slow, sluggish, dull, depressed, serious, crying, anxious, stimulated, overactive, restless, jittery, convulsive, head feels full or enlarged, floating, silly, giggling, laughing, inebriated, unable to concentrate, feeling of separateness or apartness from others, amnesia for words or numbers, stammering or stuttering speech.

Source: Miller, J.B. Food Allergy; Provocative Testing and Injection Therapy. Springfield; Charles C. Thomas, Publisher, 1972, p.21

Chemical Stressors in the Home

  • Aerosols
  • Air deodorizers
  • Aluminum pots and pans
  • Ammonia
  • Bleaches
  • Car exhaust fumes entering the house from open windows or an attached garage
  • Cedar-lined closets
  • Charcoal
  • Chlorinated or fluoridated water
  • Christmas tree needles
  • Cosmetics
  • Deodorants, anti-perspirants
  • Detergents
  • Disinfectants
  • Dyes
  • Electric Blankets (because of plastic wires)
  • Felt-tip pens
  • Flameproof mattresses
  • Floor cleaners and waxes
  • Food additives
  • Food wrapers
  • Formaldehyde (added by I.R. Bell)
  • Furniture polish
  • Gas stoves and other gas appliances
  • Hair sprays
  • Heat-sealed soft plastic packages
  • Insecticide sprays and no-pest strips
  • Lacquer
  • Medications
  • Mineral Oil
  • Mothballs and Moth Crystals
  • Mothproofed shelf paper
  • Mouthwash
  • Nail Polish
  • Newspaper print (inks and solvents)
  • Oils for fans, sewing machines, etc.
  • Oven cleaner
  • Paint Fumes
  • Paraffin
  • Perfumes, Aftershaves
  • Permanent-pressed Clothing
  • Pesticides
  • Pillowcases and Sheets of (which contain resin) Synthetics
  • Pine-scented cleaners
  • Plastics (mattress covers)
  • Refrigerant gas (check for leaks)
  • Rubber-backed carpets
  • Rubbing alcohol
  • Scented soaps
  • Shampoos
  • Shelf paper
  • Soft plastic containers and Fungicide-treated Wallpaper Wraps
  • Solvents used for duplicating machines
  • Smoke from frying foods<
  • Sponge rubber (mattresses and upholstery)
  • Stainproof upholstery and carpets
  • Synthetic clothing
  • Tablecloths, Shower Curtains, Draperies, usually contain vinyl
  • Teflon pots and pans
  • Tin Cans with phenol lining
  • Tobacco Smoke
  • Toothpaste
  • Turpentine
  • Varnishes containing Varsol

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#16 btdt

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Posted 18 May 2016 - 12:06 AM

In October 2011, a double-blind controlled study was published in PLOS ONE which suggests that rituximab can help patients with chronic fatigue syndrome, leading to a proposed theory relating chronic fatigue syndrome to other autoimmune conditions, however more research is required to verify if such a link exists.[22] A new multi-centre double-blinded trial with 152 patients began in October 2014,[23] after a follow-up open study published in July 2015 suggested a longer acting effect when four maintenance doses were added to the dosing schedule.[24] Two-thirds of the patients responded favorably to the drug, in accordance with previous findings.[25][26][27]

 

https://en.wikipedia.../wiki/Rituximab


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#17 btdt

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Posted 20 June 2016 - 07:20 PM

Another aspect of the MCS illness that is getting attention is the concept of a body burden buildup and collapse process. The body burden is an accumulation of supposedly non-toxic chemicals, often ones that came into the human environment in only the last 150 years or so, that the human body does not have explicit evolutionary protection for. These chemicals are often sequestered in fatty tissue, especially in the brain.

During a serious illness, the body can draw energy from those fatty tissue reserves. If the tissue had a buildup of chemicals, those supposedly non-toxic chemicals can be released back into the body in a sudden avalanche. If the release is within the blood chemistry of the brain, a wide range of subtle neurological injury processes are possible.

It is a common story from MCS sufferers that they think they got their MCS from a long illness, or extreme exercise, or general weight loss that did not necessarily have anything to do with pesticide, etc., exposure, that they just "never recovered from." And then their health deteriorated into the MCS condition. I.E., The illness forced the body to use fatty tissue energy reserves that caused a release of sequestered toxins.

More information is at the Environmental Working Group site -


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#18 btdt

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Posted 25 June 2016 - 02:50 AM

Genetic variants

trustworthy health information

 .Verify here .


 

 http://www.histamini...html#daoblocker

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#19 btdt

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Posted 17 February 2017 - 11:49 AM

I have learned a lot about MCS of late.  Been busy when I am not too sick. 

 

There seems to be a few resources online for MCS but in reality what I have seen in the way of support and information exchange is all connected these three sites... 

 

http://www.ei-resource.org/

 

 

seriously sensitive to pollution 

https://lindasepp.wordpress.com/

 

 

and at least one closed fb page run by the same person who signs the map

facebook.com/groups/MCSMap. Just ask for Katya.

 

So while there seems to be a lot of different resources there really isn't.  

 

I have already gotten the boot from the fb page.  I posted some information well maybe a lot of information I have found and refused to join a talk shampoo makers about my experience... whatever.  

 

We need a new group that is closed where people with MCS can say as they please. Who is up to starting one... ya me either. 

 

I still suspect the best chances for healing with come from Dr Sherry Rogers Protocol and any other detox thing you can find that works for you. 

 

You can find Dr Sherry Rogers books here

https://prestigepublishing.com/

 

So far I have read EI revised... Detox or Die and MCS... 

 

I want to read 

Tired or Toxic and a couple of others

 

wishing you all peace

 

 

seriously sensitive to pollution 


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#20 btdt

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Posted 18 February 2017 - 08:59 PM

Evaluation of Genetic Polymorphisms in Patients with Multiple Chemical Sensitivity  

   logo.plos.95.png

 

  http://journals.plos...al.pone.0073708

Objective

Multiple chemical sensitivity (MCS) is a chronic medical condition characterized by symptoms that the affect an individual’s response to low-level chemical exposure. In this study, we identified a chemical sensitive population (CSP) and investigated the effect of genetic polymorphisms on their risk of chemical sensitivity.

Methods

A quick environment exposure sensitivity (QEESI) questionnaire was used to survey 324 Japanese male workers whose DNA samples had been collected and stored. The following genes, which encode enzymes affecting the metabolic activation of a large number of xenobiotic compounds, were selected and analyzed in order to determine their influence on genetic predisposition to CSP: cytochrome P450 (CYP) 2E1, N-acetyl transferase (NAT) 2, glutathione S-transferase (GST) M1, GSTT1, GSTP1, low Km aldehyde dehydrogenase (ALDH2), and superoxide dismutase (SOD) 2.

Results

Significant case-control distributed differences were observed in SOD2 polymorphisms and allele frequency distribution in high chemical sensitive subjects. Both the significant adjusted OR of 4.30 (95% CI, 1.23–15.03) and 4.53 (95% CI, 1.52-13.51) were observed in SOD2 Ala/Ala and Val/Ala compared to Val/Val and in SOD2 Ala/Ala compared to Val/Ala compared to Val/Val genetic analysis in the high chemical sensitivity case-control study.

Conclusions

We observed that high chemical sensitive individuals diagnosed by using Japanese criteria as MCS patients were more significantly associated with SOD2 polymorphisms.

 

Previous studies have shown a some of the above snippets to be involved in mcs... the fact that this study was done on all men from the same work place limits it usefullness but does identify SOD2 not sure that was new even then. 

Still I tend to feel better about PLOs studies so I wanted to post this one I hope they do more work on mcs. 

 

 

Conclusion

The aim of this study was to examine the association between chemical sensitivity and genetic polymorphisms in CYP2E1, NAT2GSTM1GSTT1GSTP1ALDH2, and SOD2. In conclusion, we observed that the high chemical sensitive individuals who were also diagnosed by Japanese QEESI criteria as MCS patients were more significantly associated with SOD2 polymorphisms. We hypothesize that our results reflect the gene-environment associations of increased chemical sensitivity in individuals, but further studies are needed to verify our observations. We were unable to confirm previous findings of substantial importance of genetic polymorphisms in GSTM1GSTT1 and NAT2 to chemical sensitivity, but the research data are an important reference open to further exploration. A possible weakness of our study design is the lack of assessment of the environmental exposure to chemicals metabolized by the enzymes we studied. In addition, the participants of this study were limited to men from the same work site, and the cases were not classified according to any confounding factors due to sample size restriction. In future studies, we hope to classify research subjects into multiple categories according to confounding factors in order to examine the relationship between genetic polymorphisms and chemical sensitivity.


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)