Henosis

Tapering to almost-zero and staying there?

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Has anyone successfully reinstated and stabilized, tapered to almost zero (like 1mg Paxil or equivalent) and felt good enough to hang there long term? And if so, did re-instatement AD side effects (like amplified anhedonia, no emotions) or WD symptoms eventually resolve?

 

After reading horror stories about the "final jump" to zero despite long tapering, I'm wondering if it's even worth it if you are going to be non-functional for months or years and you could get your life back maintaining a tiny dose. And eventually you could keep reducing said tiny dose at even smaller increments for years to hopefully avoid W/D entirely?

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I think tapering to .01 mg using water titration, which is what i plan to do, will help you avoid post acute withdrawal syndrome. When i get there, i plan to hold at .01 mg for a couple of months at least before jumping off. There should be no lingering withdrawal from that small amount. It may take years to get to that point but i think it will be worth it. 

 

Maybe someone else can add to this thread there experience or advise.

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You can stay at whatever dose you wish.

 

If you're afraid of tapering lower than 1mg, you might stay that for a good long while and wait until you feel confident about making further decreases.

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I think tapering to .01 mg using water titration, which is what i plan to do, will help you avoid post acute withdrawal syndrome. When i get there, i plan to hold at .01 mg for a couple of months at least before jumping off. There should be no lingering withdrawal from that small amount. It may take years to get to that point but i think it will be worth it. 

 

Maybe someone else can add to this thread there experience or advise.

 

at such an insignificant dose are you experiencing standard SSRI/SNRI side effects? Did you experience anhedonia when you were on the drug? if so, did it (or other standard SSRI side effects) dissipate once you got to such a micro dose of a serotonin re-uptake inhibitor? 0.1mg in theory should barely be increasing serotonin whatsoever in your synapse.

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at such an insignificant dose are you experiencing standard SSRI/SNRI side effects? Did you experience anhedonia when you were on the drug? if so, did it (or other standard SSRI side effects) dissipate once you got to such a micro dose of a serotonin re-uptake inhibitor? 0.1mg in theory should barely be increasing serotonin whatsoever in your synapse.

 

I am tapering my anti-psychotic first, so i cant speak for ssri's at such i tiny dose, but ive read of people coming off Risperidone at .1, and having problems for a year.  My plan is to make it as small of a dose as possible before jumping off. No i have not experienced any anhedonia while on Paroxetine, but i have not started tapering it yet.

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I'd rather stay stable at a low dose (1mg of any SSRI if you will) than have to cope with the horrendous withdrawal symptoms you experience when you jump to zero.

 

With that said my goal still is to drop to zero, but this time I'm doing my withdrawal so slowly, I'm aware is going to take at least one good year to come off completely from the dosage I'm currently on (2,12mg of lexapro).

 

I've been trough a crash before, after jumping too soon, it was so bad that I will do everything to never have to feel the way I felt back then. 

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Is it possible to avoid post acute withdrawal, taking your dosage to almost an unmeasurable amount like .01 or less?

 

Any feedback is appreciated

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I tapered Prozac from 20 mg to 3.4mg over three years. The lower the dose the more extreme the withdrawal symptoms became.  When I got down to 3.4 mg dropping even minute amounts of liquid prozac ( half the space between lines on a one ML syringe) caused terrible dark, obsessive thoughts, extreme anxiety and depression so I'd go back up to 3.4mg. Finally I decided to stay at 3.4mg. I'm not perfectly fine all the time. However since beginning 500 mg of Tryptophan  and 200 of GABA a day I have felt considerably steadier.

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When I got down to 3.4 mg dropping even minute amounts of liquid prozac ( half the space between lines on a one ML syringe) caused terrible dark, obsessive thoughts, extreme anxiety and depression so I'd go back up to 3.4mg.

Yes, more or less the same here. Currently I don't have any issues with depression or anxiety, but those intrusive thoughts they come and go in waves. Ridiculous how they started at 2,27mg and not before that dosage. Lexapro is stronger than Prozac so it's sensibly the same dosage as you're taking.

Thanks God we have this shared knowledge, and I know it's not me going crazy, is just WD symptoms kicking in...

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My all time goal was to be completely free from these evil drugs, until recently I was hit so hard since getting down to 1.2mg. I have been reading day in and out lately the horror stories being off the drug years still suffering.

 

This thread opened my mind about another option. This is also consistent with my other thoughts about tapering this last mg for infinite years like super slow before jumping off when my system is already used to the almost non drug situation.

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I think tapering to .01 mg using water titration, which is what i plan to do, will help you avoid post acute withdrawal syndrome. When i get there, i plan to hold at .01 mg for a couple of months at least before jumping off. There should be no lingering withdrawal from that small amount. It may take years to get to that point but i think it will be worth it. 

 

Maybe someone else can add to this thread there experience or advise.

where can I find information on this water titration?

I am thinking that may be something I need to do.

i am taking 1/5 of a mg of liquid lexapro split into two doses, 0.1mgs AM and PM

I am still struggling a lot at this dose and thinking of possibly going up a tiny bit and staying there a LONG LONG time before I consider coming back down again

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catnapt: Water titration is another way of saying Making a liquid from a tablet or capsules . As the doses get lower and lower, you add larger quantities of water to allow you to draw smaller amounts of liquid and get the smaller desired dose.

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catnapt: Water titration is another way of saying Making a liquid from a tablet or capsules . As the doses get lower and lower, you add larger quantities of water to allow you to draw smaller amounts of liquid and get the smaller desired dose.

 

ok but what if you have a liquid already, can you add water to that? (I'm concerned it might work like trying to mix oil and water, that it might separate?)

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Lex, that only tells you how to take the liquid as it comes in the bottle

 

I'd like to know if- and how- to dilute it further so that I am taking even smaller amounts.

I currently take 0.1mL (- 0.1mg) twice a day, AM and PM

 

I want to micro taper this but the page you linked to, says not to mix this liquid with anything else.

Which is confusing, because it also says you can put the drops into a liquid you drink-

I'll C&P that part:

 

 

"Oral solution 10 mg/mL: To assist with the dosing, a syringe is provided in the pack with a scale ranging from 1 mg to 10 mg, in 1 mg increments. Dispense the required volume of solution into your drink (water, orange juice or apple juice), stir briefly then drink all of it.

Oral solution 20 mg/mL: Count the required number of drops into your drink (water, orange juice or apple juice), stir it briefly and then drink all of it.

Do not mix the LEXAPRO oral solution with other liquids and do not mix them with other medicinal products."

 

I don't know what they mean by "other liquids"- do they mean besides the water or orange or apple juice?

 

confusing!

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We can figure it out, catnapt.

 
Possible situation:

At some point you're ready to taper, you want to be cautious so decide that you'd like to reduce
by 5%, 0.005 mg from 0.1 mg to 0.095 mg.

  • Put 0.1 ml of the Lex liquid in a marked container.
  • Add water to the 100 ml line.
  • Shake or stir to distribute the Lex.
  • Remove and discard 5 ml of the solution.
  • Drink the remaining 95 ml of the solution.

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awesome! thanks, and thanks for putting it in my thread too. You rock!

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I have off prozac at 3.4mg. Whenever I've tried to drop lower however minute the drop, 

I am overwhelmed with dark repetitive thoughts and anxiety which did not let up een after six weeks.

SoI am staying at 3.4mg.I read all about the benifits of Amino acids 5-HTP and Tryptophan in Julia Ross's book The Mood Cure.

I started taking 50 mg of 5-HTP at night. It did help me sleep but invariably woke with a headache. Because it seemed to be helping me sleep and improve my mood I kept taking it in spite of the headaches. Then after a couple of weeks I noticed I was getting very anxious and weepy.

 Though  hadn't been dropping from prozac for eight months, this felt like bad withdrawal symptoms. I stopped the 5-HTP and the anxiety and crying let up. Wonder if anyone else had this kind of experience.

I also tried taking 500 mg of L-Tryptophan in the mornings with B6. I always had a strange prickling sensation in my skin, mild nausea and feeling out of breath afterwards. A bit like a flush after taking Niacin but not the same. I can't find any reports of this as a known side effect. 

It's disheartening because I thought these amino acids were working and would help me get off prozac completely (as many have done according Ross). I'd appreciate hearing  the experiences of others who nearing the end of their taper have tried amino acid support.

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P.a. agreed to taper to 75 MG with only a very small fuss. Yay

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What's wrong with juststickin g to this tiny amount?

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LawyerLiz - it's hard to answer your question without knowing to which medication you're referring. Dosage ranges vary widely for medications.

 

There's absolutely nothing wrong with staying at a low or very low dose that is effective for you. In fact telling your doctor that you want to find the lowest effective dose of a medication for you can be a good way to get their support for tapering.

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