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Mirtazipine side effects


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#1 Pokey

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Posted 17 March 2017 - 10:28 AM

I have been on 15mg of mirtazipine for a while now and Id like to know if some things I am experiencing could be side effetcs of the mirtazipine. The info out there on the web is rather general and not that helpful thus far. Here's what's going on. I wake up in the morning feeling like I'm coming out of a deep coma or unconsciousness. It reminds me of coming up from anesthesia after surgery. I feel awful in general and more specifically "heavy" and lethargic, legs are stiff and heavy, some times slightly out of breath. My BP is low and my HR as low as 50. If I get up to go pee I have to sit on the edge of the bed before standing so I'm steady. I take a BP pill and have switched to taking that in the morning which has made no difference. After I get up and have a couple cups of coffee I usually feel much better. I have a leaky mitral valve, but my cardiologist does not attribute this to my leaky valve, Ive had multiple blood test which have showed nothing, so I'm thinking it must be the mirtazipine, but I have no way to prove that except to get off. I have started a slow taper, but that will take weeks. In the mean time I was wondering if anyone here can relate to the symptoms I have been having? Thanks in advance.

 

Pokey


Was on xanax and doxepin for 25years. Got off both without to much trouble after long slow tapers. Still have issues with cognition, insomnia and fatigue. On 30mg mirtazipine now and starting taper back down to 7.5mg as a sleep aide. Also take prevacid for GERD and bystolic for a mitral valve issue plus probiotic. 


#2 ten0275

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Posted 17 March 2017 - 11:25 AM

Pokey, hey.

 

I can relate to a lot of what you describe, so it is absolutely not unlikely that the mirtazapine is causing those side effects. I remember that heavy feeling. My heavy feeling was particularly strong in my head - "lead head" i used to call it. Because it felt like someone had poured molten lead in there and my head weighed 100lbs. I also had a great deal of shortness of breath, particularly in the morning, and terrible dizziness. After a careful and slow taper, i started noticing that these side effects were waning. Now, at 1.3mg, I rarely experience them - except occasionally when I make cuts. As you taper down, you will likely also experience a lessening of the side effects. Mirt is a strange one since it activates at the higher doses and brakes at the lower doses. It's side effect profile is fairly expansive as a result - dosage-dependent. I would say if your other health concerns are in check, then what you are experiencing is probably the mirtazapine side effects.

 

hang in there,

 

dave


1996 - .5mg Ativan as needed, 7.5mg Remeron daily2008 - .5mg Xanax, Ativan discontinued, Remeron continued2012 - .5mg Xanax, .25mg Ativan 3x daily, Remeron continued2/2012 - Jumped from Remeron, continued .5mg Xanax .25mg Ativan 3x daily4/2012 - Began rapid taper of .5mg Xanax .25mg Ativan 3x daily6/2012 - Jumped from Xanax and Ativan, voluntary hospitalization followed7/2012 - 2nd voluntary hospitalization, reinstated Remeron, bumped to 30mg, also given risperidone.8/2012 - discontinued risperidone, tried gabapentin, dicontinued gabapentin, Remeron 30mg continued10/2012 to current - tapered Remeron 10% every 4 to 6 weeks (sometimes more time) using liquid compound12/2014 - 2mg Remeron 1/16/2015 - 1.9mg Remeron 8/1/2015 -1.6mg Remeron - 03/1/2016 - 1.5mg Remeron


#3 Hibari

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Posted 17 March 2017 - 12:50 PM

Hi Pokey, '

 

I definitely have those symptoms and still do even though I have tapered down pretty low.   In fact, Mirtazapine is known to be more sedating on the lower end of the medication. 

 

When I first took it I slept 12 hours a night and woke up in stupor-it would take 3 or 4 hours to wake up and lots of coffee.  When I went up in my dosage these symptoms got better. 

 

Now I am sleeping the same way again, 10 hours a night and groggy in the morning.  I also am tapering Lamictal at the same time so that contributes to my grogginess too.

 

I know from other SA members who got off Mirt that their energy and health returned.

 

Wishing you well.


September 2013-April 2014: After the death of my mom in July 2012.-became very depressed in September of 2013. Given a series of antidepressants very quickly from about 4 different psychiatrists in a 6 month period. Each one was from 1 day to 10 days at the most. My body could not handle it-I had Zoloft 4 days, Lexapro-1 day, Nortriptyline-10 days, Liquid Prozac, 1 week, Cymbalta 1 week.

December 2013-September 2014: Put on Xanax after a reaction to the Lexapro, averaging .50-1mg per day. Switched to Clonazepam-midway averaging about 0.25-0.50 daily.

June 2014: Jan/Feb 2015: Put on 7.5 Remeron titrate up to 41.25mgs 

September 2014-July 2015: Put on 25mgs of Lamictal titrate up to 200mgs daily. Also stopped the Clonzepam- never felt the wd I had experienced when I tried to stop it before (knowing nothing about withdrawal) because the Lamictal calmed me down.

 

Currently: Tapering both medications together using micro cuts. Started tapering Remeron in January 2015,  Started tapering Lamictal July 2015 Main wd symptoms-sweating, nausea, headaches, deep crying, anxiety. 12/21/16 Remeron 1.6 Lamictal 22.50 mgs 1/19/17 Remeron 1.2mgs, Lamictal 22.50mg 2/12/17 Remeron 1.2 Lamictal 21.25 mgs  3/4/17 Remeron 0.85  Lamictal 21.25 3/14 Remeron 0.85  Lamictal 20mgs

 

Additional Support: Acupuncture with Reflexology, Alanon, L-Theanine for anxiety as needed, Estradial patch 0.025, Bio-indentical Progesterone cream 150-200  Armour Thyroid 90mgs.


#4 Pokey

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Posted 17 March 2017 - 03:51 PM

Hibari and Dave: thanks for the come back. I think the best thing for me to do is get off the stuff. Its caused me to gain weight too and I dont need the extra pounds at my age. LAst summer I was at 30mg, but it jazzed me up to much. Seems like you can't win with these drugs. I was on xanax for a long time and that took 20 months to get off. Anyway thanks for the details of your experience. Would appreciate any other folks who want to share their experience. Thanks much folks

 

Paul aka Pokey.


Was on xanax and doxepin for 25years. Got off both without to much trouble after long slow tapers. Still have issues with cognition, insomnia and fatigue. On 30mg mirtazipine now and starting taper back down to 7.5mg as a sleep aide. Also take prevacid for GERD and bystolic for a mitral valve issue plus probiotic. 


#5 Hibari

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Posted 17 March 2017 - 04:04 PM

I gained 30 lbs. Just list 10 and am looking forward to losing the rest!

September 2013-April 2014: After the death of my mom in July 2012.-became very depressed in September of 2013. Given a series of antidepressants very quickly from about 4 different psychiatrists in a 6 month period. Each one was from 1 day to 10 days at the most. My body could not handle it-I had Zoloft 4 days, Lexapro-1 day, Nortriptyline-10 days, Liquid Prozac, 1 week, Cymbalta 1 week.

December 2013-September 2014: Put on Xanax after a reaction to the Lexapro, averaging .50-1mg per day. Switched to Clonazepam-midway averaging about 0.25-0.50 daily.

June 2014: Jan/Feb 2015: Put on 7.5 Remeron titrate up to 41.25mgs 

September 2014-July 2015: Put on 25mgs of Lamictal titrate up to 200mgs daily. Also stopped the Clonzepam- never felt the wd I had experienced when I tried to stop it before (knowing nothing about withdrawal) because the Lamictal calmed me down.

 

Currently: Tapering both medications together using micro cuts. Started tapering Remeron in January 2015,  Started tapering Lamictal July 2015 Main wd symptoms-sweating, nausea, headaches, deep crying, anxiety. 12/21/16 Remeron 1.6 Lamictal 22.50 mgs 1/19/17 Remeron 1.2mgs, Lamictal 22.50mg 2/12/17 Remeron 1.2 Lamictal 21.25 mgs  3/4/17 Remeron 0.85  Lamictal 21.25 3/14 Remeron 0.85  Lamictal 20mgs

 

Additional Support: Acupuncture with Reflexology, Alanon, L-Theanine for anxiety as needed, Estradial patch 0.025, Bio-indentical Progesterone cream 150-200  Armour Thyroid 90mgs.


#6 Hopefull

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Posted 25 March 2017 - 11:16 PM

Hi to everyone,

The weight gain from Mitrazapine has made me feel low latley.
I have gained 10kg. I have always been slim and had fast metabolism.
I never carried fat around my stomach and since I have been on Mitrazapine, I have gained fat around my abdomen. Not only that, I feel like I look a bit puffy in the face. I don't feel like I look like my normal self.
This is starting to really bother me.
I have not lost any weight, despite taking a low dose of Mitrazapine. I have not gained any more weight appart from 10kg.

Can someone please let me know, if you start loosing weight after you completely stop taking Mitrazapine? Have any of you developed a little pot belly from taking Mitrazapine? Does it mean that my metabolism has permanently been altered by Mitrazapine?
It did not bother me so much before, but it is now.
I really would appreciate your feedback.

DRUG HISTORY:

 

November 2013- Zoloft, ( Bad reaction).

January 2014 - March 2014 Seroquel.( Quit Cold Turkey).

January2014- Mirtazapine, I was taking 15mg at one stage, reduced to 7.5mg, Pgad reactions to Mirtazapine. Doctor kept increasing it to 37.5mg, until July 2014. No improvement, experiencing panic attacks, on 37.5 mg. I had enough by October 2014. Began tapering.

October 2014- Started tapering Mirtazapine from 37.5mg.

September 2015- Down to 4mg of Mirtazapine. Crashed.

September 16th- Up dosed to 5mg. Held this dose for almost 5 months. Stabilised.

February 2016- Began tapering again. From 5mg to 4.5mg of Mirtazapine. (Rocking the boat, again)! Lol. :(


#7 Hibari

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Posted 26 March 2017 - 07:45 AM

HI Hopeful,

 

People have lost weight after Mirtazapine.  I have just lost 13Lbs of the 30 I put on. 

 

 

My lasts posts on my thread from #531 onward talk about it and you will see Free Spirit's response. 

 

 

It can be done!


September 2013-April 2014: After the death of my mom in July 2012.-became very depressed in September of 2013. Given a series of antidepressants very quickly from about 4 different psychiatrists in a 6 month period. Each one was from 1 day to 10 days at the most. My body could not handle it-I had Zoloft 4 days, Lexapro-1 day, Nortriptyline-10 days, Liquid Prozac, 1 week, Cymbalta 1 week.

December 2013-September 2014: Put on Xanax after a reaction to the Lexapro, averaging .50-1mg per day. Switched to Clonazepam-midway averaging about 0.25-0.50 daily.

June 2014: Jan/Feb 2015: Put on 7.5 Remeron titrate up to 41.25mgs 

September 2014-July 2015: Put on 25mgs of Lamictal titrate up to 200mgs daily. Also stopped the Clonzepam- never felt the wd I had experienced when I tried to stop it before (knowing nothing about withdrawal) because the Lamictal calmed me down.

 

Currently: Tapering both medications together using micro cuts. Started tapering Remeron in January 2015,  Started tapering Lamictal July 2015 Main wd symptoms-sweating, nausea, headaches, deep crying, anxiety. 12/21/16 Remeron 1.6 Lamictal 22.50 mgs 1/19/17 Remeron 1.2mgs, Lamictal 22.50mg 2/12/17 Remeron 1.2 Lamictal 21.25 mgs  3/4/17 Remeron 0.85  Lamictal 21.25 3/14 Remeron 0.85  Lamictal 20mgs

 

Additional Support: Acupuncture with Reflexology, Alanon, L-Theanine for anxiety as needed, Estradial patch 0.025, Bio-indentical Progesterone cream 150-200  Armour Thyroid 90mgs.