I have been on 15mg of mirtazipine for a while now and Id like to know if some things I am experiencing could be side effetcs of the mirtazipine. The info out there on the web is rather general and not that helpful thus far. Here's what's going on. I wake up in the morning feeling like I'm coming out of a deep coma or unconsciousness. It reminds me of coming up from anesthesia after surgery. I feel awful in general and more specifically "heavy" and lethargic, legs are stiff and heavy, some times slightly out of breath. My BP is low and my HR as low as 50. If I get up to go pee I have to sit on the edge of the bed before standing so I'm steady. I take a BP pill and have switched to taking that in the morning which has made no difference. After I get up and have a couple cups of coffee I usually feel much better. I have a leaky mitral valve, but my cardiologist does not attribute this to my leaky valve, Ive had multiple blood test which have showed nothing, so I'm thinking it must be the mirtazipine, but I have no way to prove that except to get off. I have started a slow taper, but that will take weeks. In the mean time I was wondering if anyone here can relate to the symptoms I have been having? Thanks in advance.