Jump to content

If you find useful information here, your gift would help keep this site going. Our staff is entirely volunteer.

- - - - -

Targum, 2014 Identification and treatment of antidepressant tachyphylaxis.

  • Please log in to reply
No replies to this topic

#1 Altostrata



  • Administrators
  • PipPipPipPipPipPip
  • 24,005 posts
  • LocationSan Francisco, CA

Posted 27 March 2017 - 09:43 PM

Innov Clin Neurosci. 2014 Mar;11(3-4):24-8.
Identification and treatment of antidepressant tachyphylaxis.
Targum SD1.

Abstract at https://www.ncbi.nlm...d/24800130 Freefull text at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008298/

Antidepressant tachyphylaxis describes a condition in which a depressed patient loses a previously effective antidepressant treatment response despite staying on the same drug and dosage for maintenance treatment. It has been suggested that antidepressant tachyphylaxis is a form of relapse related to evolving drug tolerance, but it is also clear that there are other possible reasons for the loss of treatment response unrelated to tolerance, such as medication nonadherence. It has been reported that depressed patients with "true" antidepressant tachyphylaxis may be less responsive to new treatment interventions. Therefore, it is important to identify these patients as part of a comprehensive treatment planning process.

Antidepressant; antidepressant tachyphylaxis; antidepressant tolerance; breakthrough depression; drug tolerance; major depressive disorder

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.