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Tips for tapering off Seroquel (quetiapine)


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#109 RubyTuesday

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Posted 28 July 2016 - 01:17 PM

I just unfollowed this topic because when I get notifications by email, with questions that I have answers for, and I then follow the thread back to the forum and can't find the question I was trying to answer, it feels like a big waste of my time. Also, I don't like having my posts moved around and not being able to find them. If I could find them, that would be one thing. But I can't. This has  been going on for quite a long time. I just now decided to say something about it. Unfollowed.


2002: "Situational depression" 2002-2010:Prozac.Birth Control.2011 Short trials: Paxil, Celexa, Lexipro, Wellbutrin, Xanax, Ativan- Gee, Doc never mentioned protracted AD wd syndrome. Imagine that. 2011-2015. Lamictal. Seroquel. Remiron. 2012: "Complex post traumatic stress disorder." Fast taper of Remiron jumped off June 2013. Slow tapers ever since of Seroquel & Lamictal.  crippling muscle spasms. crying fits. panic attacks. akathisia. nerve twitches. the jitters. the heebie jeebies. de-personal/realization. numbness. tingling. fatigue. lethargy. nightmares.insomnia. weird images. eye pain.vertigo. dizziness. brain zaps. and on and on and on. withdrawal? side effects? which drug? impossible to know. applied for disability. awaiting case to be settled.also back in school slowly & carefully. have not worked full time in 10 years. NOW: Seroquel 12.5 mg. Lamictal 75% of 50 mg. 

GOT DISABILITY. USING THE ROAD BACK JAMES HARPER VITAMIN SUPPLEMENTS. OFF OF SEROQUEL OCTOBER 2, 2015. Tapered off Lamictal approx 5 mg per month until Wednesday April 23 2016 jumped off at about 20 mg. (dissolved in water.) Feel great mentally & emotionally but physically like a mild flu, achey, heavy, dizzy, uncoordinated but nonetheless still better than the last few months of tapering. Worked Fall 2015 while withdrawing Seroquel then quit all school & work again February 2016 in order to get off the drugs.p.s. the worst of the morning panic disappeared the morning I stopped the Lamictal.

http://robertwhitake...n Epidemic.html

 

 


#110 Altostrata

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Posted 30 July 2016 - 03:23 PM

Sorry to hear that, RT. Sometimes we do move posts, most often to Intro topics, because they're more appropriate there. Discussions of individual situations would take this topic off-topic, as it's mostly a reference topic about tapering.

 

Your experience with Seroquel is very valuable. Perhaps you might look for people tapering Seroquel in the Intro forum and post in their topics?


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

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#111 MNgal1960

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Posted 02 August 2016 - 04:47 AM

Thank you, Shep. I tapered my Q from 25mg down to 17mg and found I had anxiety and neuropathy. I am also on Valium with one previous failed taper attempt. I wondered if the Q taper was causing my symptoms or if it was somehow tangled up with the Valium. The gabapentin is supposed to help with Restless Leg Syndrome and neuropathy but doesn't seem to do much. I particularly wonder about the neuropathy because I have it from an illness, also, but it was particularly bad during the taper. It makes it so hard to know if I'm tapering too fast or if it's just my "typical" neuropathy flaring up. Grrrr.

 

At any rate, I am pausing my Q taper here and going to try an ultra-slow taper of the V to get it lower. I wonder if it will be similar to the Q (which was also ultra-slow). Wish I could get all the way off the Q because it messes up my mornings, I can't drive or function until at least 10AM even though I'm awake at 6AM.

 

I'm so tired and so frustrated by how slow this process is.


2005-2006 Rapid taper off of Zoloft. Horrible but survived. Adverse drug reaction to Prozac.

2010-2013 Night panics. All typical sleep aids failed. Diagnosed with complex PTSD.

2013-present: Valium (5mg x 3) prescribed by pro-benzo doctor. Helped me sleep for awhile. Then sleep began to get worse again.

Nov. 2014 Switched doctors. New doctor was anti-benzo but thought a 3-month taper was a slow taper. Failed and reinstated. Added 25mg Seroquel for sleep.

Sept. 2015 Made occasional very small dry cuts to the Seroquel. Down to 20mg. Did not notice much change in symptoms.

March 2016 Reduced gabapentin by 20% by accident and backed up again. (Was trying to feel less sedated.) Reduced again more slowly to 200+200+300.

Sept 2016 Down to 16.5mg of Seroquel. Disabling neuropathy and sleep poor. Backed up to 19mg. Improved.

October 2016 Liquefied one V tablet. Neuropathy back immediately. Waiting to liquefy another.

November 2016 All 3 tablets now dissolved. I think the windows are getting a little more frequent but they don't last long. Sleep poor.

January 2017 Felt stable enough to try daily microtaper. Started at 3% and inched up to almost 10%. Became very unstable. Terrors back. Neuropathy back.

February 2017 Holding again. Slow improvements.

March 2017 Neuropathy back to tolerable. Making very tiny cuts, about 3%/month.


#112 rapunzel2

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Posted 02 August 2016 - 10:30 PM

question about seroquel. when the withdrawal insomnia passes, will the sleep actually improve with lower seroquel dose? if it has been taken only for sleep with doses 25-50mg?

 

is it like antidepressants, which may induce depression when taken long term, then depression is withdrawal symptom, and then when all that resolves, depression gets better. 


in 2002- cipramil for half a year, ended it uneventfully. in 2006 - citalopram for half a year, ended in horrific state, ditched the drugs CT. 2006-2008 not feeling well but drug free. in 2008 prozac 20mg + quetiapine 25mg. 2009 tried to stop, ended up in hole after couple of months, started zoloft. 2009-2011 zoloft 50mg. went to 25mg in 2011 summer, it resulted in half a year horrible suffering. reinstated, changed drugs, nothing happened. by 2012 beginning suddenly felt great and CT meds. after 4 months came suddenly most horrible human suffering that's possible. started tapering slowly, GFCF diet and Hardy Nutritionals vitamins in 2013 summer. 

current medications: 1) fluoxetine and quetiapine since Aug 2012; 2) Daily Essential Nutrients by Hardy Nutritionals 10 capsules / since May 2013 + omega3; 3) Gluten-free-casein-free diet since june 2013; 4) free form amino acid complex 3 capsules 5) milk thistle 6) niacin 1500mg

25. april'13 fluoxetine 40mg -> 36mg (10%); 25. may'13 fluoxetine 36mg -> 32mg (1 month inbetween, 11%); 4. july'13 fluoxetine 32mg-> 28mg (5,5 weeks, 13%); 27. july'13 quetiapine 50 -> 45mg (10%); 15. aug'13 fluoxetine 28mg -> 24mg (6 weeks, 14%); 29. sept'13 quetiapine 45 -> 40mg (1,5 months, 11%); 14. oct'13 quetiapine 40mg -> 35mg (2 weeks, 13%); 16. oct'13 quetiapine 35mg -> 40mg; 17. oct'13 fluoxetine 24mg -> 22 mg (8%); 4. feb’14 fluoxetine 22mg -> 21mg (3,5 months hold inbetween, 5% cut); 21. feb'14 fluoxetine 21mg -> 20,5mg (2,5 weeks, 2,4% cut); 27 feb'14 fluoxetine 20,5mg -> 20mg (1 week, 2,4% cut); 30 mar'14 fluoxetine 20mg -> 19,5mg (4,5 weeks, 2,4% cut); 17 may'14 quetiapine 40mg -> 31mg (22% cut); 31 may'14 fluoxetine 19,5mg -> 17,56mg (9,9%); 13 july'14 quetiapine 31mg -> 25mg (19% cut); 19 july'14 quetiapine 25mg -> 18, 75mg (25% cut, 6 days); 28. july'14 quetiapine 18,75mg -> 22mg (-15%); 9. aug'14 fluoxetine 17,52mg -> 17,12mg (2,3% cut, 10 weeks, over 2 months); 19. aug'14 back to 17,52mg due to bad withdrawal symptoms; 20. oct'14 fluoxetine 17,52 -> 17,2mg (1,8% cut); 28. nov'14 fluoxetine 17,2 -> 15,6 (9,8%); 9. feb’15 fluoxetine 15,6 -> 14,4 (7,7%); 3. may’15 quetiapine 22mg -> 19mg (-14%); 27. may’15 fluoxetine 14,4mg -> 12,6mg (-12,5%, 1,8mg); 2. july’15 fluoxetine 12,6mg -> 10,6mg (15,9%, 2mg); 26. oct'15 fluoxetine 10,6mg - 9mg (15%, 1,6mg); 18. jan'16 quetiapine 18mg -> 15mg (17%); 16. mar'16 fluoxetine 9mg -> 7,4mg (18%); 22.may'16 fluoxetine 7,4mg -> 6mg (19%); 19.sept'16 quetiapine 12,5 -> 11,25 (10%); 26. sept'16 quetiapine 11,25 -> 10,25 (9%), 3 oct'16 quetiapine 10,25 -> 9,25 (10%); 10 oc'16 quetiapine 9,25-> 8,25mg (11%), 14 nov'16 quetiapine 8,25 -> 7,25 (12%); 9 Jan'17 fluoxetine 6mg -> 5,8mg (3%): 18 jan fluoxetine 5,8mg -> 5,6mg (3%); 6 feb fluoxetine 5,6mg -> 5,4mg (4%); 19 feb fluoxetine 5,4mg -> 5,2mg (4%); 5 mar fluox 5,2 -> 5,0 (4%). 

 


#113 VitaminB

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Posted 06 August 2016 - 07:35 PM

Just some information from another post. My son had his first psychotic break when trying to come off Seroquel. Phillip Seeman has published a number of papers on Seroquel and why it is so difficult to come off it. Although it has been years since I read up on the drug, I believe that Seeman's work indicated that, like Clozapine, Seroquel binds poorly to the dopamine receptors and, when cutting back, it is easily displaced by Dopamine (American Journal of Psychiatry 1999; 156:876-884).

 

The so called, "therapeutic" level is right around (give or take 50 Mgs) 250 Mgs. It is right around this dosage that reductions should be very conservative, 10% or less. Doctors do not understand withdrawal and frequently recommend reductions of Seroquel of 50 Mgs or more. People on this site, who know far more than I do, will give you better advice.

 

I know receptor occupancy is far from the whole story, but I do think that knowledge of them can point to some of the "cliffs" to avoid. Any doctors advice about bouncing the drug up and down depending on how you are feeling is just plain wrong. My son was once on 1200 Mgs of Seroquel when he was in the hospital (years ago). The psychiatrist there responded to my alarm by telling me he had had people on 2,000 Mgs. My son is stable today, and will soon be starting to withdraw from his current med (Abilify). It would also probably help some people trying to understand how Seroquel works (or doesn't) to look at a post on "thelastpsychiatrist" from 2007. The guy can be a smart aleck and, at times, inappropriate, but seems to know his science. Be well, Ed

 

 

 

Sadly, I am in the same boat as your son in terms of landing back in the hospital trying to go down from 250mg. 

I have read that article from the last psychiatrist too... I haven't really stayed at 600mg for long and haven't been dosed higher than that... maybe at 800mg for a while. 


I have been on Seroquel since 2008 because Seroquel doesn't cause akathisia (in my case) and all other drugs do.   

 

I am tapering slowly off Seroquel- 393.75mg--now (400mg, Mid Oct) (406.25, Mid Sept) (412.5mg, Early Sept) (425mg, Aug) 

 

I have been going for 3% decreases... landed in the hospital. 

 

Now I am on 300mg Clozaril. To plans to taper because they take my blood levels. 

 
 

 


#114 simack

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Posted 09 August 2016 - 12:19 AM

Hello all I just have a quick question regarding tapering Seroquel. I recently made the switch from a 50mg instant release tablet to 50ml of liquid Seroquel. I did this simply by letting one 50mg tablet dissolve into 50ml of water then drinking it.
However doing this caused me to become destabilised... Is it safe to taper this way? I know this can happen switching to liquid medication, but does anyone know what's happening here? Am I experiencing an increase our decrease in dose?

MEDS HISTORY

2004 hospitalized for acute alcohol induced psychosis and started on my psych drug merry-go-round.2004-2006 SSRI > SNRI Merry-go-round finally settled on Effexor. Also was started on Risperdal in 2004 but switched to seroquell after I had a bad reaction to it.2008. Was switched from Effexor to pristiq, Also managed to successfully Quit Seroquel Cold Turkey.Asenapine- 5mg- August 2014 ~ May 2015. Was put on for Social Anxiety, was great at first then started developing disabling side effects, did a rapid taper and so started my withdrawal nightmare...

MEDS CURRENT

Pristiq-100mg ~ Currently holding

Olanzapine- 3.75mg May 2015 ~ Currently tapering by -.06mg per week (Jan 2016, 3.5mg  ~Feb 2016 intractable insomnia updose to 3.75mg)

Quetiapine- 50mg June 2015  ~Dec 25 2015 Quit cold turkey. ~(Feb 6 2016 hit with intractable insomnia - reinstated 50mg.)

August 2016 : Became destabilised after messing around with cutting doses, trying THC oil etc, Holding on for dear life hoping to stabilise again someday.. 

Supplements Ashwaghanda,  melatonin 2mg, fish oil, Magnesium.


#115 VitaminB

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Posted 09 August 2016 - 01:13 AM

I read through this thread completely today. Is there anyone out there who as gone off Seroquel from high doses of 600? 

 

I am at 425 (100 morning) (325 at night)...... can I dissolve a 100mg pill and take a solid 200mg pill when I get to below 300 at night? The taper might be way easier at a slow 3% pace by liquid titration. 25's and 50's are mentioned in the liquid titration process, has anyone done 100mg pills?  I could taper my morning dose this way too. 


I have been on Seroquel since 2008 because Seroquel doesn't cause akathisia (in my case) and all other drugs do.   

 

I am tapering slowly off Seroquel- 393.75mg--now (400mg, Mid Oct) (406.25, Mid Sept) (412.5mg, Early Sept) (425mg, Aug) 

 

I have been going for 3% decreases... landed in the hospital. 

 

Now I am on 300mg Clozaril. To plans to taper because they take my blood levels. 

 
 

 


#116 MNgal1960

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Posted 09 August 2016 - 04:02 AM

I have read in other places about switching to liquid being destabilizing to some people and then you have to wait to stabilize to actually taper.

 

I don't know anything about getting off high doses except I have read people doing it. The problem with the larger pills is it either makes a very strong suspension or you have to use a ton of water. I tried liquid for awhile and used 100ml of water for 25mg Seroquel tablet. The stronger the liquid, the more you are affected my tiny errors in measuring.  The weaker, the less. Maybe someone who has used larger tablets could chime in.

 

I think Seroquel doesn't actually dissolve, only disintegrates. You have to be sure to shake and shake before doing a pull out of the medication because the tiny particles are just floating around in the water and not actually dissolved, so they could sink back to the bottom.


2005-2006 Rapid taper off of Zoloft. Horrible but survived. Adverse drug reaction to Prozac.

2010-2013 Night panics. All typical sleep aids failed. Diagnosed with complex PTSD.

2013-present: Valium (5mg x 3) prescribed by pro-benzo doctor. Helped me sleep for awhile. Then sleep began to get worse again.

Nov. 2014 Switched doctors. New doctor was anti-benzo but thought a 3-month taper was a slow taper. Failed and reinstated. Added 25mg Seroquel for sleep.

Sept. 2015 Made occasional very small dry cuts to the Seroquel. Down to 20mg. Did not notice much change in symptoms.

March 2016 Reduced gabapentin by 20% by accident and backed up again. (Was trying to feel less sedated.) Reduced again more slowly to 200+200+300.

Sept 2016 Down to 16.5mg of Seroquel. Disabling neuropathy and sleep poor. Backed up to 19mg. Improved.

October 2016 Liquefied one V tablet. Neuropathy back immediately. Waiting to liquefy another.

November 2016 All 3 tablets now dissolved. I think the windows are getting a little more frequent but they don't last long. Sleep poor.

January 2017 Felt stable enough to try daily microtaper. Started at 3% and inched up to almost 10%. Became very unstable. Terrors back. Neuropathy back.

February 2017 Holding again. Slow improvements.

March 2017 Neuropathy back to tolerable. Making very tiny cuts, about 3%/month.


#117 scallywag

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Posted 09 August 2016 - 04:47 AM

When changing from a tablet to liquid formulation, it can be helpful to make the switch in steps. Liquids are absorbed more quickly in our digestive systems.

 

Start with a small portion of your dose as liquid and take the rest in tablet/capsule. For example, If you're taking 200 mg, take 50 mg as liquid and the remainder as the tablet. Do that for a few weeks *or* longer, then go to half liquid half tablet.

 

If you have questions about your specific dosage please post your questions in your intro thread.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.
1997-1999 Effexor; 2002-2005 Effexor XR 37.5 mg linear taper, dropping same #beads/week with bad results
Cymbalta (brand name), 60 mg 2012 - 2015; 20 mg to 7 mg in 2016, taper details in this post;
2017: 6.3 (58 beads) Feb. 1; 5.6 mg (52) Feb. 22; 5.4 mg (50) Mar. 15;
Current dose: 5.1 mg (47 beads) 2017-Mar-25
+ Supplements: fish oil (1500 mg EPA/500 mg DHA), Vitamins: D3, K2, C; Minerals: Mg, Se, Cr, I, V
scallywag's Introduction
Online spreadsheet for dose taper calculations and nz11's THE WORKS spreadsheet


#118 VitaminB

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Posted 11 August 2016 - 07:36 PM

I have read in other places about switching to liquid being destabilizing to some people and then you have to wait to stabilize to actually taper.

 

I don't know anything about getting off high doses except I have read people doing it. The problem with the larger pills is it either makes a very strong suspension or you have to use a ton of water. I tried liquid for awhile and used 100ml of water for 25mg Seroquel tablet. The stronger the liquid, the more you are affected my tiny errors in measuring.  The weaker, the less. Maybe someone who has used larger tablets could chime in.

 

I think Seroquel doesn't actually dissolve, only disintegrates. You have to be sure to shake and shake before doing a pull out of the medication because the tiny particles are just floating around in the water and not actually dissolved, so they could sink back to the bottom.

 

Thanks for the tip on it being destabilizing. I am on 100morning and 325night right now, so maybe I could dissolve the 25mg at night to see how it effects me. 

 

I saw that seroquel does come in a liquid from one of Alto's posts. I will have to look into that if the tablets are going to be stubborn dissolving. 

 

 

 

 

scalawagWhen changing from a tablet to liquid formulation, it can be helpful to make the switch in steps. Liquids are absorbed more quickly in our digestive systems.

 

Start with a small portion of your dose as liquid and take the rest in tablet/capsule. For example, If you're taking 200 mg, take 50 mg as liquid and the remainder as the tablet. Do that for a few weeks *or* longer, then go to half liquid half tablet.

 

If you have questions about your specific dosage please post your questions in your intro thread.

 

 

Ok. I will go back to intro thread. Thanks for the heads up on taking it slow. 


I have been on Seroquel since 2008 because Seroquel doesn't cause akathisia (in my case) and all other drugs do.   

 

I am tapering slowly off Seroquel- 393.75mg--now (400mg, Mid Oct) (406.25, Mid Sept) (412.5mg, Early Sept) (425mg, Aug) 

 

I have been going for 3% decreases... landed in the hospital. 

 

Now I am on 300mg Clozaril. To plans to taper because they take my blood levels. 

 
 

 


#119 MNgal1960

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Posted 13 August 2016 - 04:19 AM

Does anyone have any reliable data on whether or not Seroquel will remain stable in water or Ora-Plus or any liquid so one could make up a few days supply at a time? Thanks.


2005-2006 Rapid taper off of Zoloft. Horrible but survived. Adverse drug reaction to Prozac.

2010-2013 Night panics. All typical sleep aids failed. Diagnosed with complex PTSD.

2013-present: Valium (5mg x 3) prescribed by pro-benzo doctor. Helped me sleep for awhile. Then sleep began to get worse again.

Nov. 2014 Switched doctors. New doctor was anti-benzo but thought a 3-month taper was a slow taper. Failed and reinstated. Added 25mg Seroquel for sleep.

Sept. 2015 Made occasional very small dry cuts to the Seroquel. Down to 20mg. Did not notice much change in symptoms.

March 2016 Reduced gabapentin by 20% by accident and backed up again. (Was trying to feel less sedated.) Reduced again more slowly to 200+200+300.

Sept 2016 Down to 16.5mg of Seroquel. Disabling neuropathy and sleep poor. Backed up to 19mg. Improved.

October 2016 Liquefied one V tablet. Neuropathy back immediately. Waiting to liquefy another.

November 2016 All 3 tablets now dissolved. I think the windows are getting a little more frequent but they don't last long. Sleep poor.

January 2017 Felt stable enough to try daily microtaper. Started at 3% and inched up to almost 10%. Became very unstable. Terrors back. Neuropathy back.

February 2017 Holding again. Slow improvements.

March 2017 Neuropathy back to tolerable. Making very tiny cuts, about 3%/month.


#120 scallywag

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Posted 13 August 2016 - 05:00 AM

MNgal: Alto's post on the first page answers a lot of questions, including the one you're asking.

Her answer is that the liquid is "probably stable for 24 hours." Please also read the part where she talks about switching over to liquid in stages -- initially taking most of your dose in tablet form then gradually increasing the amount you take as liquid.

Alto's post about Seroquel

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.
1997-1999 Effexor; 2002-2005 Effexor XR 37.5 mg linear taper, dropping same #beads/week with bad results
Cymbalta (brand name), 60 mg 2012 - 2015; 20 mg to 7 mg in 2016, taper details in this post;
2017: 6.3 (58 beads) Feb. 1; 5.6 mg (52) Feb. 22; 5.4 mg (50) Mar. 15;
Current dose: 5.1 mg (47 beads) 2017-Mar-25
+ Supplements: fish oil (1500 mg EPA/500 mg DHA), Vitamins: D3, K2, C; Minerals: Mg, Se, Cr, I, V
scallywag's Introduction
Online spreadsheet for dose taper calculations and nz11's THE WORKS spreadsheet


#121 freespirit123

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Posted 13 August 2016 - 05:33 AM

I wasn't on for that long so maybe that had something to do with it, a few months. But I have a digital scale and just chipped away each night. I was on Lunesta at the time so I'm sure that helped
Never been on a drug in my life, Had UTI was put on several antibiotics & lost my sleep.
Seroqoil in Sept '15
Was put on Ativan &/or Klonopin, stopped both Lunesta in Aug '15 3mg
Celexa since Oct '15 40mg
UPDATE as of Aug 15,2016
OFF ALL except celexa 40mg 🙏
Supplements: Fish Oil, 1000mg D3, 500mg B12, Probiotics, prebiotics, Standard Process Hypothalamus PMG, Theanine serene with relora
Very spiritual and meditate daily. Positive thinking can accomplish a lot! READ Effortless Sleep Method, life changing!

#122 MNgal1960

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Posted 13 August 2016 - 07:28 AM

Thanks Scallwag. I wasn't sure. I thought that the 24 hours was referring to the extended release form. My brain isn't working so well. I will try to read it again.

 

FreeSpirit, I have been trying to use a digital scale and dry cutting, but I find it so frustrating and my scale is hard to calibrate. I was hoping I could make up a batch of liquid more easily. But if I have to make a fresh batch every day, that will also be too difficult for me. I'm not in good shape and am usually alone.


2005-2006 Rapid taper off of Zoloft. Horrible but survived. Adverse drug reaction to Prozac.

2010-2013 Night panics. All typical sleep aids failed. Diagnosed with complex PTSD.

2013-present: Valium (5mg x 3) prescribed by pro-benzo doctor. Helped me sleep for awhile. Then sleep began to get worse again.

Nov. 2014 Switched doctors. New doctor was anti-benzo but thought a 3-month taper was a slow taper. Failed and reinstated. Added 25mg Seroquel for sleep.

Sept. 2015 Made occasional very small dry cuts to the Seroquel. Down to 20mg. Did not notice much change in symptoms.

March 2016 Reduced gabapentin by 20% by accident and backed up again. (Was trying to feel less sedated.) Reduced again more slowly to 200+200+300.

Sept 2016 Down to 16.5mg of Seroquel. Disabling neuropathy and sleep poor. Backed up to 19mg. Improved.

October 2016 Liquefied one V tablet. Neuropathy back immediately. Waiting to liquefy another.

November 2016 All 3 tablets now dissolved. I think the windows are getting a little more frequent but they don't last long. Sleep poor.

January 2017 Felt stable enough to try daily microtaper. Started at 3% and inched up to almost 10%. Became very unstable. Terrors back. Neuropathy back.

February 2017 Holding again. Slow improvements.

March 2017 Neuropathy back to tolerable. Making very tiny cuts, about 3%/month.


#123 MNgal1960

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Posted 17 August 2016 - 03:41 AM

I have been holding and dry cutting for weeks and have been continued to experience a big spike in my neuropathy. Could the inaccuracy of dry cutting Seroquel cause neuropathy? I have heard suspensions are more accurate, but I don't know if I'm mentally up to figuring out how to make a suspension. The directions are so confusing and I can't afford OraPlus.

 

Has anyone ever heard of tapering Seroquel causing neuropathy? It could be something else. I've had it in the past from other triggers. I am trying to figure out what the trigger could be. I'm barely functioning.

 

Sorry if I asked this elsewhere and forgot. My memory is shot.


2005-2006 Rapid taper off of Zoloft. Horrible but survived. Adverse drug reaction to Prozac.

2010-2013 Night panics. All typical sleep aids failed. Diagnosed with complex PTSD.

2013-present: Valium (5mg x 3) prescribed by pro-benzo doctor. Helped me sleep for awhile. Then sleep began to get worse again.

Nov. 2014 Switched doctors. New doctor was anti-benzo but thought a 3-month taper was a slow taper. Failed and reinstated. Added 25mg Seroquel for sleep.

Sept. 2015 Made occasional very small dry cuts to the Seroquel. Down to 20mg. Did not notice much change in symptoms.

March 2016 Reduced gabapentin by 20% by accident and backed up again. (Was trying to feel less sedated.) Reduced again more slowly to 200+200+300.

Sept 2016 Down to 16.5mg of Seroquel. Disabling neuropathy and sleep poor. Backed up to 19mg. Improved.

October 2016 Liquefied one V tablet. Neuropathy back immediately. Waiting to liquefy another.

November 2016 All 3 tablets now dissolved. I think the windows are getting a little more frequent but they don't last long. Sleep poor.

January 2017 Felt stable enough to try daily microtaper. Started at 3% and inched up to almost 10%. Became very unstable. Terrors back. Neuropathy back.

February 2017 Holding again. Slow improvements.

March 2017 Neuropathy back to tolerable. Making very tiny cuts, about 3%/month.


#124 Justin

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Posted 18 August 2016 - 06:57 AM

I have been holding and dry cutting for weeks and have been continued to experience a big spike in my neuropathy. Could the inaccuracy of dry cutting Seroquel cause neuropathy? I have heard suspensions are more accurate, but I don't know if I'm mentally up to figuring out how to make a suspension. The directions are so confusing and I can't afford OraPlus.

 

Has anyone ever heard of tapering Seroquel causing neuropathy? It could be something else. I've had it in the past from other triggers. I am trying to figure out what the trigger could be. I'm barely functioning.

 

Sorry if I asked this elsewhere and forgot. My memory is shot.

 

Hi MNgal1960,

Sorry to hear about your difficulties.  I have been following some of the previous instruction in order to cut down on Seroquel.  Specifically, every 2 weeks or so I reduce the dose by 5%.  This is a slightly more conservative way of reducing 10% per month as others on this board recommend.  This approach works well for me.  I'm using the following scale in order to weigh the pills:  https://amzn.com/B0012TDNAM.  I use a razor blade to cut them.  If you have trouble with the cutting being inaccurate and the target weight is difficult to achieve you could have your doctor prescribe you with multiple pills of smaller doses and cut down the smaller mg pills (for instance, rather than cutting down 50mg pill I find it easier to cut down a single 25mg pill and take that along with a whole 25mg pill in order to get back to the 47.5mg range..)

-Justin



#125 MNgal1960

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Posted 18 August 2016 - 07:30 AM

 

I have been holding and dry cutting for weeks and have been continued to experience a big spike in my neuropathy. Could the inaccuracy of dry cutting Seroquel cause neuropathy? I have heard suspensions are more accurate, but I don't know if I'm mentally up to figuring out how to make a suspension. The directions are so confusing and I can't afford OraPlus.

 

Has anyone ever heard of tapering Seroquel causing neuropathy? It could be something else. I've had it in the past from other triggers. I am trying to figure out what the trigger could be. I'm barely functioning.

 

Sorry if I asked this elsewhere and forgot. My memory is shot.

 

Hi MNgal1960,

Sorry to hear about your difficulties.  I have been following some of the previous instruction in order to cut down on Seroquel.  Specifically, every 2 weeks or so I reduce the dose by 5%.  This is a slightly more conservative way of reducing 10% per month as others on this board recommend.  This approach works well for me.  I'm using the following scale in order to weigh the pills:  https://amzn.com/B0012TDNAM.  I use a razor blade to cut them.  If you have trouble with the cutting being inaccurate and the target weight is difficult to achieve you could have your doctor prescribe you with multiple pills of smaller doses and cut down the smaller mg pills (for instance, rather than cutting down 50mg pill I find it easier to cut down a single 25mg pill and take that along with a whole 25mg pill in order to get back to the 47.5mg range..)

-Justin

 

Thanks, Justin. I am trying to cut down the smallest tablet available using a filet-type knife that is almost as thin as a razor blade and a mg scale. I'm just really bad at it. On multiple meds. Tired and clumsy, so my manual dexterity isn't the greatest.

 

I'm below 25mg and have been going v-e-r-y slowly. I also have an autoimmune disorder so sometimes it's impossible to tell if the illness is causing the symptoms or the taper is too fast. Or if I'm just the world's worst dry cutter! :P

 

I'm glad to hear things are going well for you so far. It sounds like you are a good dry cutter.


2005-2006 Rapid taper off of Zoloft. Horrible but survived. Adverse drug reaction to Prozac.

2010-2013 Night panics. All typical sleep aids failed. Diagnosed with complex PTSD.

2013-present: Valium (5mg x 3) prescribed by pro-benzo doctor. Helped me sleep for awhile. Then sleep began to get worse again.

Nov. 2014 Switched doctors. New doctor was anti-benzo but thought a 3-month taper was a slow taper. Failed and reinstated. Added 25mg Seroquel for sleep.

Sept. 2015 Made occasional very small dry cuts to the Seroquel. Down to 20mg. Did not notice much change in symptoms.

March 2016 Reduced gabapentin by 20% by accident and backed up again. (Was trying to feel less sedated.) Reduced again more slowly to 200+200+300.

Sept 2016 Down to 16.5mg of Seroquel. Disabling neuropathy and sleep poor. Backed up to 19mg. Improved.

October 2016 Liquefied one V tablet. Neuropathy back immediately. Waiting to liquefy another.

November 2016 All 3 tablets now dissolved. I think the windows are getting a little more frequent but they don't last long. Sleep poor.

January 2017 Felt stable enough to try daily microtaper. Started at 3% and inched up to almost 10%. Became very unstable. Terrors back. Neuropathy back.

February 2017 Holding again. Slow improvements.

March 2017 Neuropathy back to tolerable. Making very tiny cuts, about 3%/month.


#126 genlady

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Posted 28 August 2016 - 02:06 PM

From personal experience, coming off Seroquel was a nightmare.  I was on 600mg. and tapered by 25mg. per month and still had sweating/chills, vomiting, mood swings, hallucinations, pychotic epidoses, head burning sensations, dizziness, sensitive to light and sound, vision problems.  Be very careful if you are sensitive to chemicals like I am .  While on anti depressants I was very sensitive to the side effects as well.  


Medications:  Trazodone, Lamotrigine, Klonopin for over 10 years   all at maximum dosages,:Disconcontinued Klonopin in month of February 2011,  discontinued Trazodone and Lamotrigine   in month of March 2011 while in hosptial.  Given Seroquel to "help" go off Klonopin  gradually increased to 600 mg ; doctor took me off 600 mg. Seroquel in two weeks, and switched to Resperidal  because of weight gain on Seroquel, went off Resperidal quickly,   then gradually reinstated  Seroquel to 600 mg. at my request.   Went off Seroquel by myself at 25mg. per month in 2014.     Last medication Seroquel completely off since May 2016. Also went off Morphine at the same time as last 25 mg. of Seroquel in May 2016. Started tapering 40mg. to 35mg. Celexa on 11 Aug. 2016  ; 16 Oct. Celexa 32.5 mg.; 6 Nov. 2016:  30mg. , 50 mg abt. Feb 26 with occasional 30mg.  , 40 mg. Mar 20

 

Supplements :Xiao yao San; Magnesium: 500mg. three x   day., Omega 3's: 3,000 mg.

 2 Multi-Vitamin,Vitamin D: 500 mg. 3x day,  Glycine 1000mg.

Medications presently taking:  Celexa 40mg,  Lyrica 150mg. 2x day  , Synthroid 175mcg, Tylenol 3's  every four hours.  ,  anarca  ; Nasonex 2 sprays each nostril, once a day    

  

 


#127 genlady

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Posted 28 August 2016 - 02:08 PM

I have been holding and dry cutting for weeks and have been continued to experience a big spike in my neuropathy. Could the inaccuracy of dry cutting Seroquel cause neuropathy? I have heard suspensions are more accurate, but I don't know if I'm mentally up to figuring out how to make a suspension. The directions are so confusing and I can't afford OraPlus.

 

Has anyone ever heard of tapering Seroquel causing neuropathy? It could be something else. I've had it in the past from other triggers. I am trying to figure out what the trigger could be. I'm barely functioning.

 

Sorry if I asked this elsewhere and forgot. My memory is shot.

I experienced neuropathy while coming off Seroquel.  I have been off of it for five months and still have it, but not as severe.  


Medications:  Trazodone, Lamotrigine, Klonopin for over 10 years   all at maximum dosages,:Disconcontinued Klonopin in month of February 2011,  discontinued Trazodone and Lamotrigine   in month of March 2011 while in hosptial.  Given Seroquel to "help" go off Klonopin  gradually increased to 600 mg ; doctor took me off 600 mg. Seroquel in two weeks, and switched to Resperidal  because of weight gain on Seroquel, went off Resperidal quickly,   then gradually reinstated  Seroquel to 600 mg. at my request.   Went off Seroquel by myself at 25mg. per month in 2014.     Last medication Seroquel completely off since May 2016. Also went off Morphine at the same time as last 25 mg. of Seroquel in May 2016. Started tapering 40mg. to 35mg. Celexa on 11 Aug. 2016  ; 16 Oct. Celexa 32.5 mg.; 6 Nov. 2016:  30mg. , 50 mg abt. Feb 26 with occasional 30mg.  , 40 mg. Mar 20

 

Supplements :Xiao yao San; Magnesium: 500mg. three x   day., Omega 3's: 3,000 mg.

 2 Multi-Vitamin,Vitamin D: 500 mg. 3x day,  Glycine 1000mg.

Medications presently taking:  Celexa 40mg,  Lyrica 150mg. 2x day  , Synthroid 175mcg, Tylenol 3's  every four hours.  ,  anarca  ; Nasonex 2 sprays each nostril, once a day    

  

 


#128 MNgal1960

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Posted 29 August 2016 - 08:00 AM

Hi gen. I'm sorry to hear you still have neuropathy. I decided to try liquifying my Seroquel so that my dosing was more stable and so I could make much smaller cuts in hopes of making my symptoms less severe. I just can't seem to make small enough cuts with my mg scale.


2005-2006 Rapid taper off of Zoloft. Horrible but survived. Adverse drug reaction to Prozac.

2010-2013 Night panics. All typical sleep aids failed. Diagnosed with complex PTSD.

2013-present: Valium (5mg x 3) prescribed by pro-benzo doctor. Helped me sleep for awhile. Then sleep began to get worse again.

Nov. 2014 Switched doctors. New doctor was anti-benzo but thought a 3-month taper was a slow taper. Failed and reinstated. Added 25mg Seroquel for sleep.

Sept. 2015 Made occasional very small dry cuts to the Seroquel. Down to 20mg. Did not notice much change in symptoms.

March 2016 Reduced gabapentin by 20% by accident and backed up again. (Was trying to feel less sedated.) Reduced again more slowly to 200+200+300.

Sept 2016 Down to 16.5mg of Seroquel. Disabling neuropathy and sleep poor. Backed up to 19mg. Improved.

October 2016 Liquefied one V tablet. Neuropathy back immediately. Waiting to liquefy another.

November 2016 All 3 tablets now dissolved. I think the windows are getting a little more frequent but they don't last long. Sleep poor.

January 2017 Felt stable enough to try daily microtaper. Started at 3% and inched up to almost 10%. Became very unstable. Terrors back. Neuropathy back.

February 2017 Holding again. Slow improvements.

March 2017 Neuropathy back to tolerable. Making very tiny cuts, about 3%/month.


#129 lanah

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Posted 03 March 2017 - 01:25 AM

I read that Shep only slept for 3 hours when she hit 12 mgs, i'm in the same place now also only sleeping 3 hours. I've been holding for three months now and i still get those 
nights. So i was wondering if this is typical around this dosage? 
 


Several ssri's, antipsychotics, opiads and benzo's since 2003.

Flurazepam: rapid taper after 6 weeks usage in beginning of march 2015

Trazodone: rapid taper from 50ms to 0mgs end of july 2015

Current medication:12 mgs seroquel (from 25mgs)


#130 MNgal1960

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Posted 03 March 2017 - 07:51 PM

I have read of people who have only taken half of a 25mg tablet for sleep, so 12.5mg. These people were not withdrawing though. It was their regular dose.


2005-2006 Rapid taper off of Zoloft. Horrible but survived. Adverse drug reaction to Prozac.

2010-2013 Night panics. All typical sleep aids failed. Diagnosed with complex PTSD.

2013-present: Valium (5mg x 3) prescribed by pro-benzo doctor. Helped me sleep for awhile. Then sleep began to get worse again.

Nov. 2014 Switched doctors. New doctor was anti-benzo but thought a 3-month taper was a slow taper. Failed and reinstated. Added 25mg Seroquel for sleep.

Sept. 2015 Made occasional very small dry cuts to the Seroquel. Down to 20mg. Did not notice much change in symptoms.

March 2016 Reduced gabapentin by 20% by accident and backed up again. (Was trying to feel less sedated.) Reduced again more slowly to 200+200+300.

Sept 2016 Down to 16.5mg of Seroquel. Disabling neuropathy and sleep poor. Backed up to 19mg. Improved.

October 2016 Liquefied one V tablet. Neuropathy back immediately. Waiting to liquefy another.

November 2016 All 3 tablets now dissolved. I think the windows are getting a little more frequent but they don't last long. Sleep poor.

January 2017 Felt stable enough to try daily microtaper. Started at 3% and inched up to almost 10%. Became very unstable. Terrors back. Neuropathy back.

February 2017 Holding again. Slow improvements.

March 2017 Neuropathy back to tolerable. Making very tiny cuts, about 3%/month.