Jump to content

If you find useful information here, your gift would help keep this site going. Our staff is entirely volunteer.

Photo
- - - - -

Tips for tapering off Paxil (paroxetine)


  • Please log in to reply
33 replies to this topic

#1 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,887 posts
  • LocationSan Francisco, CA

Posted 26 May 2011 - 04:52 PM

aka Aropax, Paroxat, Deroxat, Rexetin, Sereupin, Seroxat, Xetanor

Paxil and Effexor have long led the list of antidepressants notorious for difficult withdrawal, the others being Zoloft and Luvox. (But this may be because Paxil and Effexor have been very widely prescribed for a long time; Lexapro and Cymbalta are certainly also very difficult to taper.)

From the July 2011 Medication Guide from GlaxoSmithKline here (PDF) http://us.gsk.com/pr...ts/us_paxil.pdf


Discontinuation of Treatment With Paxil

Recent clinical trials supporting the various approved indications for Paxil employed a taper-phase regimen, rather than an abrupt discontinuation of treatment. The taper-phase regimen used in GAD and PTSD clinical trials involved an incremental decrease in the daily dose by 10 mg/day at weekly intervals. When a daily dose of 20 mg/day was reached, patients were continued on this dose for 1 week before treatment was stopped.

With this regimen in those studies, the following adverse events were reported at an incidence of 2% or greater for Paxil and were at least twice that reported for placebo: Abnormal dreams, paresthesia, and dizziness. In the majority of patients, these events were mild to moderate and were self-limiting and did not require medical intervention.

During marketing of Paxil and other SSRIs and SNRIs, there have been spontaneous reports of adverse events occurring upon the discontinuation of these drugs (particularly when abrupt), including the following: Dysphoric mood, irritability, agitation, dizziness, sensory disturbances (e.g., paresthesias such as electric shock sensations and tinnitus), anxiety, confusion, headache, lethargy, emotional lability, insomnia, and hypomania. While these events are generally self-limiting, there have been reports of serious discontinuation symptoms.

Patients should be monitored for these symptoms when discontinuing treatment with Paxil. A gradual reduction in the dose rather than abrupt cessation is recommended whenever possible. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, then resuming the previously prescribed dose may be considered. Subsequently, the physician may continue decreasing the dose but at a more gradual rate....

....
Discontinuation of Treatment With Paxil

Symptoms associated with discontinuation of Paxil have been reported (see PRECAUTIONS: Discontinuation of Treatment With Paxil). Patients should be monitored for these symptoms when discontinuing treatment, regardless of the indication for which Paxil is being prescribed. A gradual reduction in the dose rather than abrupt cessation is recommended whenever possible. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, then resuming the previously prescribed dose may be considered. Subsequently, the physician may continue decreasing the dose but at a more gradual rate.


From FDA prescribing information at http://www.drugs.com/pro/paxil.html

  • Regular Paxil comes in 10, 20, 30, and 40 mg tablets (also true of generic paroxetine).
  • Paxil CR comes in 12.5, 25, and 37.5 mg tablets.
  • Paxil Oral Suspension (liquid) comes in a concentration of 10 mg/5ml

Reduce by 10% per month to start
The 10% rule holds for Paxil, like other psychiatric drugs: Reduce by 10% per month, calculated on the last dosage. (The amount of the reduction gets progressively smaller.)

See Why taper by 10% of my dosage?

Cutting up tablets
To reduce your dosage, cut regular Paxil tablets up with a pill cutter, available at any drug store.

If you get your prescription filled with the 10mg tablets, you may be able to cut them in half or quarters to reduce by 5mg or 2.5mg at a time.

Paxil CR tablets are enteric-coated and not designed to be split. Switch to regular Paxil if you wish to cut up the tablets.

Precisely weighing tablet pieces or crushed tablets with an electronic digital scale
You may wish to precisely measure your dosage with an electronic scale that measures milligrams. These are available for under $30 US. See Using a digital scale to measure doses

Use Paxil liquid to taper
This is the easiest and most accurate way to taper Paxil.

See FDA prescribing information at http://www.drugs.com/pro/paxil.html

Paxil Oral Suspension (liquid) comes in a concentration of 10 mg/5ml.

The ordering code for brand-name Paxil orange-colored, orange-flavored, 10mg/5 ml, in 250 ml white bottles is NDC 0029-3215-48 (http://www.hipaaspac...es/0029-3215-48 )

 

Some people are sensitive to changes in the form of the drug. If you are taking tablets, you may wish to take part of your daily dosage in tablet form and part in liquid for a few days to ease the transition from tablets to liquid.

Use oral syringes to taper with the liquid, see http://survivinganti...ing-techniques/

Make your own liquid
You can make your own liquid with water. See How to make a liquid from tablets or capsules

 

Using a combination of tablets or capsules and liquid

Rather than switch directly to an all-liquid dose, you may wish to take part of your dose in liquid and part in lower-dose tablets or capsules, gradually converting to all liquid as you get to lower dosages. This can be very convenient and reduce any problems switching from one form of the drug to another.

 

If your doctor prescribes liquid and tablets or capsules at the same time, most likely, he or she will have to indicate "divided doses" in the prescriptions to get the drugs covered by insurance.

 

Have a compounding pharmacy make up capsules of smaller dosages
With a prescription, a compounding pharmacy will accurately weigh small doses and put them into capsules for you. This is usually somewhat expensive. See http://survivinganti..._3001#entry3001


Edited by Altostrata, 28 August 2015 - 03:05 PM.
updated

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#2 KatyM

KatyM

    Getting started

  • Members
  • Pip
  • 4 posts
  • LocationPalmdale,California

Posted 11 July 2011 - 11:26 AM

I was on 12.5 for 3 years...After my son went in the Army and my boss was awful to me.....I quit my job and started a new one...Then my son went to Iraq...Wow they bumped me up to 25....Now Im doing ok my son is coming home and I love my job...Also I have Colitis for about 10 years....Big flare up when they bumped me up to 25...I am 56 years old and gaining weight like crazy....Want off of Paroxitine now...Doctor sais take the 25 for 2 more weeks....Then go down to the 12.5 for 2 weeks than every other day....Like i said yoyo...I was told I cant cut these pills cause they are time released....I dont think there is a smaller dose than what i am taking? Help!!!!

#3 Brandy

Brandy

    Silver star

  • Members
  • PipPipPip
  • 620 posts
  • Location...

Posted 11 July 2011 - 01:28 PM

Your doctor is giving you a common taper schedule that DOES NOT WORK for most people! This is something doctors just don't know about yet. Withdrawal schedules that work for some other kinds of medications are disasters with medications like paroxetine and so many others. Most people who follow taper schedules like that one end up with big problems - not always immediately, but fairly soon.

 

Then doctors think their "original condition" is worse and tell them they have to go back on medication - often switching them to a newer, allegedly "better" med which compounds the problems because they often don't help the withdrawal but create a new addiction and its own set of side effects and sooner or later (often sooner!) another withdrawal on top of the first one. Aaaaargh! But fortunately you realized there were problems sooner than many of us did, so you can avoid this medication merry-go-round.

 

Please be sure and read the entire thread about tapering that I linked to in my response to your other post. (That thread explains a lot of things far better than I could!) Don't let it overwhelm you! Just get familiar with the concepts and options, and then you'll get lots of personal responses to help you find what's suitable for you, and help and support as you do a slow, safe taper where you won't be a human yo-yo! (And will have a lot less problems in the future!)

 

It never hurts to go slower, and it gives your body much better circumstances for healing from the changes the med makes while taking it. That's the key issue to recovering well and having quality of life while you do! Your doctor is right that you can't cut the "CR" extended release ones, but that's not a problem! In order to do a slow taper that will avoid the problems you're having (and many more!), you need to switch to regular paroxetine. It's the same medication, and the "extended release" of the CR seems to be deceptive. I've never used that form, but from what I've read, it's simply coated to delay it's absorbing into your system.

 

People don't have problems switching from cr (extended release) to regular; it's switching to other meds, even in the same drug family, that so often causes new problems. I'd suggest you switch to the liquid (suspension) form of paroxetine. You don't need to do that right away, but pretty soon that will be the best way to accurately measure out the small doses to do 10% (or whatever percentage works for you; some people need to drop by even less) drops after stabilizing on each new dose after taking each dose for 3-6 weeks or more to stabilize on it and be ready to drop further.

 

Your doctor will need to prescribe the form of paroxetine you'll need. See if he'll prescribe it in the liquid suspension form for you. 20 mg. will be the equivalent of 25 mg cr's as far as I know. Once you get that (let us know if your doctor refuses, but he or she should accept that you feel more comfortable tapering very slowly, and if they don't, remind them that it can't hurt to go slow!), take 20 mg. every single day (no alternating days!!!!) and then we'll help you learn how to taper safely from there. By the way, I'm not surprised your colitis got worse on the higher dose.

 

Digestive problems often are exacerbated by these meds. But don't rush your taper! Tapering too fast would make it far worse than the med itself does. That's because the lining of the intestine needs to heal, and too-fast tapering interferes with that healing. It's very common to gain weight on this med. You most likely will lose the weight you gained in a while, but that can't be rushed by faster tapering. And it can take a while after tapering, but it will happen!


Edited by KarenB, 18 October 2016 - 09:48 PM.
added paragraph spacing

I was "TryingToGetWell" (aka TTGW) on paxilprogress. I also was one of the original members here on Surviving Antidepressants

 

I had horrific and protracted withdrawal from paxil, but now am back to enjoying life with enthusiasm to the max, some residual physical symptoms continued but largely improve. The horror, severe derealization, anhedonia, akathisia, and so much more, are long over.

 

My signature is a temporary scribble from year 2013. I'll rewrite it when I can.

 

If you want to read it, click on http://survivinganti...nyone/?p=110343


#4 Shanti

Shanti

    Gold star

  • Members
  • PipPipPipPip
  • 1,091 posts
  • LocationNorthern California

Posted 21 October 2011 - 12:08 PM

My doctor wasn't cooperating with me to get Liquid Paxil so I talked to my Pharmacist and he said he doesn't need a new prescription from my Doctor. So he is ordering it for me. I just thought others should know this in case their Doctors aren't cooperating. Does anyone know how much it costs? I'm only concerned now that I'll have to pay out of pocket for it and it'll be too expensive.
Taper from Cymbalta, Paxil, Prozac & Antipsychotics finished June 2012.
Xanax 5% Taper - (8/12 - .5 mg) - (9/12 - .45) - (10/12 - .43) - (11/12 - .41) - (12/12 - .38)
My Paxil Website
My Intro

#5 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,887 posts
  • LocationSan Francisco, CA

Posted 21 October 2011 - 01:41 PM

Google and you shall find. When you do, please post here. Shanti, you can combine a half-tablet with liquid to make up your dosage, if your insurance will cover the tablet but not the liquid. That will make the liquid go farther.
This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#6 Shanti

Shanti

    Gold star

  • Members
  • PipPipPipPip
  • 1,091 posts
  • LocationNorthern California

Posted 23 October 2011 - 02:10 PM


I Googled. And it looks like around $200. I hope it's covered! Or maybe there's a generic of it and cheaper. I'll post how much it is when I get it.


Unfortunately, I believe that price is for the generic liquid. The brand is even pricier! That's why a lot of people who can't afford it (like me) wait until they are at a lower dose so the liquid lasts longer. They usually come in 250ml bottles and 2.5ml=5mg. At your current dose a bottle will last you 27 days. If you were at 10mg a bottle would last you 50 days.

Wow. If my insurance doesn't cover it then I'm just gonna have to get digital scales and use the tablets. That's just crazy!
Taper from Cymbalta, Paxil, Prozac & Antipsychotics finished June 2012.
Xanax 5% Taper - (8/12 - .5 mg) - (9/12 - .45) - (10/12 - .43) - (11/12 - .41) - (12/12 - .38)
My Paxil Website
My Intro

#7 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,887 posts
  • LocationSan Francisco, CA

Posted 23 October 2011 - 05:28 PM

You can combine tablets and liquid, use the liquid for the odd bits of dosage. For example, you can cut a 30mg tablet in half and take the 15mg tablet piece with 3.5mg liquid to make 18.5mg. If you can get a full prescription for 30mg tablets, the tablets will last you 2 months.
This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#8 Shanti

Shanti

    Gold star

  • Members
  • PipPipPipPip
  • 1,091 posts
  • LocationNorthern California

Posted 24 October 2011 - 10:45 AM

Well, my insurance doesn't cover the liquid and it's $600! Wow. So I'm going to get a digital jewelers scale at eBay or somewhere.
Taper from Cymbalta, Paxil, Prozac & Antipsychotics finished June 2012.
Xanax 5% Taper - (8/12 - .5 mg) - (9/12 - .45) - (10/12 - .43) - (11/12 - .41) - (12/12 - .38)
My Paxil Website
My Intro

#9 Shanti

Shanti

    Gold star

  • Members
  • PipPipPipPip
  • 1,091 posts
  • LocationNorthern California

Posted 24 October 2011 - 11:06 AM

I was able to get a jeweler's scale and a pill crusher all under $25. Much better than $600! Anyone that is shopping for one, make sure it measures to mg. I saw a lot that only measured grams.
Taper from Cymbalta, Paxil, Prozac & Antipsychotics finished June 2012.
Xanax 5% Taper - (8/12 - .5 mg) - (9/12 - .45) - (10/12 - .43) - (11/12 - .41) - (12/12 - .38)
My Paxil Website
My Intro

#10 arcticmonkey

arcticmonkey

    Member

  • Members
  • PipPip
  • 11 posts
  • LocationMacedonia

Posted 13 May 2014 - 12:09 PM

Is making a liquid solution from paxil a good idea ?

Anyone had any success with this ?

In what paxil/water ratio should the solution be ?

 

I'm currently down to 5 mg paxil,and I need a way to make very small reductions in dosage,which is not possible by cutting the pill.So I need someone to elaborate the method of making a liquid solution from paxil.

 

Also has anyone here gotten visual snow because of antidepressant withdrawal ?



#11 primrose

primrose

    Silver star

  • Members
  • PipPipPip
  • 357 posts
  • Locationchippenham UK

Posted 13 May 2014 - 04:07 PM

Is making a liquid solution from paxil a good idea ?

Anyone had any success with this ?

In what paxil/water ratio should the solution be ?

 

I'm currently down to 5 mg paxil,and I need a way to make very small reductions in dosage,which is not possible by cutting the pill.So I need someone to elaborate the method of making a liquid solution from paxil.

 

Also has anyone here gotten visual snow because of antidepressant withdrawal ?

Hi

 

I get visual snow if I haven't slept well.

 

As for making a liquid out of paxil in order to make tiny reductions, I can only share my experience of doing the same thing but with seroquel, the drug I am currently tapering from.

 

Im not saying my way is right, but it's working for me.

 

My starting dose was 25mg four times a day.

My cut is 2mg a day.

I got four small jars, and using a big marked syringe, I squirted 50ml in each jar.

So 50ml = 25mgs and one ml = 0.5mgs.

To achieve my 2mg a day cut, I cut one more ml of liquid each day from each of the 4 dose jars.

That's half a mg from each 6hrly dose jar, times that by four to give 2mg for each day.

I use smaller syringes to measure out my doses.

I am sure to shake each jar, get the lid off and plunge my syringe in there as fast as I can to draw my daily dose, because when the drug is in suspension, the particles can settle on the bottom, so keeping them suspended and moving makes for as accurate a dose as possible.

 

I will admit, I've forgotten a few doses and therefore havnen't stuck to every 6 hrs strictly, but, so far, its been cool, no withdrawal symptoms, but like I said, I am on the constant  lookout for the telltale sneezes and runny nose, which are the withdrawal symptoms I have got, before tapering, about a day after not taking my dose, for whatever reason.

 

This way is experimental for me, I am my own guinea pig.

Nothing ventured, nothing gained.

 

My thinking behind it was to keep as even a level of seroquel in my blood as possible, by taking every 6hrs. The half life is 6 ish hours, hence me dosing every 6hrs.

 

The daily cut means that the taper is a smooth descent.

 

I previously tapered from 200mg to 100mg in weekly 10mg steps.

If you were to plot my previous stepped taper, and this current smoother daily taper on a graph, the stepped one would look just that, a jagged, stepped line down.

The daily taper would look like a smooth curve.

 

So far, it's working for me.

I know what to do if symptoms appear.


pregan taper 600mg down to 240mg, daily cuts since xmas

valium, just over 75mg, tapering 0.1 a day, will keep this more udated, cos amounts going down

i have borderline personality, chronic ptsd, and suspected adhd and substance misuse as a symptom, which i am addressing with help of medical staff, drugs agencies & mh sta


#12 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,887 posts
  • LocationSan Francisco, CA

Posted 13 May 2014 - 04:19 PM

arcticmonkey, please see the first post in this topic and the other discussion in this topic.

 

primrose, making a liquid from Paxil and tapering is much more simple than the method you're using to go off Seroquel.

 

Also, reducing 2mg a day from 40mg Seroquel after being on it for years and recently going off benzos -- that's probably way too fast. I hope it doesn't catch up with you in a bad way.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#13 primrose

primrose

    Silver star

  • Members
  • PipPipPip
  • 357 posts
  • Locationchippenham UK

Posted 13 May 2014 - 04:27 PM

arcticmonkey, please see the first post in this topic and the other discussion in this topic.

 

primrose, making a liquid from Paxil and tapering is much more simple than the method you're using to go off Seroquel.

 

Also, reducing 2mg a day from 40mg Seroquel after being on it for years and recently going off benzos -- that's probably way too fast. I hope it doesn't catch up with you in a bad way.

Hi Alto

 

Thanks for  your concern. :)

 

I have tapered down from 100mg not 40mg. (sorry, you looked at my sig, I'll change that to 28mg.

 

I'll be sure to reduce my cut if those sneezes and that runny nose comes back.

As I said above, these two things are an early warning sign of seroqeul withdrawals.

 

So far so good though, thankfully. :D


pregan taper 600mg down to 240mg, daily cuts since xmas

valium, just over 75mg, tapering 0.1 a day, will keep this more udated, cos amounts going down

i have borderline personality, chronic ptsd, and suspected adhd and substance misuse as a symptom, which i am addressing with help of medical staff, drugs agencies & mh sta


#14 SetMeFree

SetMeFree

    Member

  • Members
  • PipPip
  • 33 posts
  • LocationWhite Plains,NY

Posted 20 January 2015 - 03:59 PM

Im down to 7 MG of Paxil.. Dropping 10 % reductions every 6 weeks.. I notice the more I cut the pills and expose the raw side of the pill.The more and more it irritates my Gi tract.Feels like my insides get beat up. Does anyone have these issues???

2002 22.5mg paxil Cr for anxiety 2003 22.5 quit cold nighmare 2004 30mg paxil 2005 30mg quit cold nightmare 2006-2010 40mg-50mg generic paxil 2011 20mg 2011 MAY 10mg paxil then swithched to prozac failure..bad GI ISSUES 2011 sept back too 25 paxil .. major GI Issues 1 year and a 1/2..2012 15mg ..figuring it out. 2012 june paxil liquid to 14mg GI Issues disappeared!!2012 oct 13mg..1 mg a month weaning. 2013 Feb. 9mg headaches.Mar 2013 8.5mg, 3/27 7.6mg 4/24 7 Mg.. Made it back to 7mg 2015 but Im not using Liquid it irritated me to much.. Cutting the pills down..Bad GI Issues..


#15 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,887 posts
  • LocationSan Francisco, CA

Posted 20 January 2015 - 07:49 PM

You might put it in a gelatin capsule and see if that helps.

 

Please update your Introductions topic.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#16 MapleleafGirl

MapleleafGirl

    Silver star

  • Members
  • PipPipPip
  • 137 posts
  • LocationVancouver, B.C, Canada

Posted 21 January 2015 - 12:37 PM

i used compounded pills from the pharmacy...my doctor gave me the prescriptions and i took them to a compounding pharmacy and they would make me up the exact doses..worked really well..


Michele aka MapleLeafGirl

Paxil Free Since June 1st 2014

Was on Paxil for 8.5 years on and off from 2001

Did a 4 year successful taper off 20mgs of Paxil

My Successful Tapering Story: http://survivinganti...ered-off-paxil/

Tapering Schedule:

3rd attempt at withdrawal going slow..compounded pills
05/27/2010 - 03/12/12: Tapered From 20mgs - 6.2 (2nd year into Taper)
04/11/2012 - 6.0 - 3.4 - 05/05/2013 (Third year into Taper)
06/04/2013 - 3.2 - 1.0 - 05/31/2014 (Fouth and Final Year of Taper)

February 9th 2016 month 20 off paxil and four year taper..experiencing a horrible wave bad bad bad

May 2016 Made the decision to go back on an SSRI  - Currently on Escitalopram 10mgs but planning to taper at some point in the near future


#17 Cheeky

Cheeky

    Silver star

  • Members
  • PipPipPip
  • 222 posts
  • LocationAustralia

Posted 03 February 2015 - 11:48 PM

My pharmacy is going to make me a liquid Paxil, I will be eventually tappering from 40mg of paxil, what ml should I ask ? I can half and quater the tablets and will add the liquid paxil to it.


-1995 to 2014 started at 20mg for 10 years and slowly increased it to 50mg Paxil-2014 8th of October 25mg Seraquel Started -2014 Tapered of Aropax from Oct 16th to 22nd Nov in only 1 week-2014 Oct 25th started Cymbalta on 30mg fo 1 week Nov 7th 60mg Cymbalta for 2 weeks and Nov 25th -28th 90mg Cymbalta - plus 50mg Seraquel-Tapered of Cymbalta from Nov 28th to 7th Dec - started Zoloft 50mg on the 8th of Dec-12th Dec 75mg Zoloft 16th Dec 100mg Zoloft and still on the 50mg Seraquel-2015 6th Jan 25mg Seraquel 15th Jan 125mg Zoloft and 50mg seraquel-21st Jan 20mg Paxil plus 50mg Seraquel 24th of Jan 30mg Paxil 27th of Jan 40mg Paxil<p>-started Seraquel Tapper Febuary 24th to 43.7mg then March 29th 37.5mg of seraquel May 6th 31.25mg May 28th 25mg4th Nov 21mg Seraquel 14th feb 12.5 Seraquel and still on 40mg PaxilCurrently 12.5mg Seraquel1st may started my Paxil tapper 5% 38mg 16th June 5% 36.8mg 23rd July 35.5mg August 6th 35mg
August 23rd 34.5mg currently 19th October 40mg Paxil and 50mg Seraquel at night 2nd November 43mg Seraquel

17th March 2017 39.5mg  Paxil and 43mg Seraquel


#18 ladybug

ladybug

    Silver star

  • Members
  • PipPipPip
  • 524 posts
  • LocationTexas

Posted 04 February 2015 - 05:54 PM

My pharmacy is going to make me a liquid Paxil, I will be eventually tappering from 40mg of paxil, what ml should I ask ? I can half and quater the tablets and will add the liquid paxil to it.

 

With the ready-made liquid Paxil 2.5ml=5mg. Most people are able to make small drops with this ratio if they use a 1ml syringe. Hope this helps!


a.k.a JMarie

Paxil since Mar.1998

2006-2007:40-20mg
2009: 20mg to 14mg 2010: 14mg to 10.5mg 2011: 10.5 to 7.6mg  2012: 7.5 to 6.8mg

2013: 6.7-6.3mg 2014: 6.2mg-5.8mg 2015: 5.7 to 5.15mg

01/06/16:5.1mg

02/20/16: 5.0mg

05/28/16: 4.9mg

07/09/16: 4.8mg

09/02/16: 4.7mg

10/27/16: 4.6mg


#19 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,887 posts
  • LocationSan Francisco, CA

Posted 04 February 2015 - 08:01 PM

If your pharmacy is going to make it, you can get it any concentration you wish. Probably 1mg per milliliter is the easiest to calculate: If you are reducing by 4mg, you would take 4mL using an oral syringe that holds 5mL.

 

Discuss this with your pharmacist.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#20 JessicaEva85

JessicaEva85

    Getting started

  • Members
  • Pip
  • 1 posts
  • LocationSeattle, WA

Posted 22 March 2015 - 05:03 PM

How low should you go when doing a 10% taper every 28 days with Paxil?


Paxil since 2004

2004 - Started at 25mg CR

2005 - Upped to 50mg CR

2008 - Reduced by 5mg a month to 25mg CR (it was the worst thing ever!) :wacko:

2012 - Switched to non-CR Paxil at 20mg

2014 - Discovered PaxilProgress and started a 10% every 28days 

April 2014 to Sept. 2014 - 18mg to 9.6mg

Sept. 2014 to March 2015 - 9.6mg

March 2015 - 8.6mg

 


#21 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,887 posts
  • LocationSan Francisco, CA

Posted 22 March 2015 - 05:24 PM

Jessica, you need to see how dosage reductions affect you. Most people need to reduce to under 1mg before discontinuing completely.

 

Please start a topic for yourself in the Introductions forum to track your progress and questions.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#22 DLB

DLB

    Silver star

  • Members
  • PipPipPip
  • 298 posts
  • LocationNew York

Posted 23 March 2015 - 02:19 AM

Exactly Alto, I have been under 1mg. since the beginning of December and I initially thought I would have been off by Christmas but here it is 3 months later and now at about .14 mg and doing ok. This is a real tricky part of the tapering process.
Paxil start September 2003 due to Fluoroquinolone adverse reaction that I wish doc. knew what it was. 10mg. most of the time with a few short runs of 20mg. FAST tapered 3 times and finally hit poop out or a reaction to nsaid's in Nov.2013. Started a 10% taper Jan. 2014 and have been ok until Sept 14 and went through a short hell. Now plodding through and looking for the light with unrelenting insomnia and pain, fog, loss of interests....<p>12/20/14 - .8mg.
1/01/15 - .75 mg.
1/15/15 - .42 mg. better sleep now, hope it continues...
2/11-15 - .25 mg. doing really good!! 2 weeks feel 85% of old me!
3/17/15 .14 mg. Knee pain bad!
4/07/15 .05 mg. this is so small now that I am estimating and just licking it off palm small as a "." And I'm using small text..
4/13/15 NOTHING !!!! Took my last little micro dose on 4/12/15. 😃👍👍👍

#23 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,887 posts
  • LocationSan Francisco, CA

Posted 25 March 2015 - 11:29 AM

I agree, DLB. Thank you for adding your experience here.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#24 Toulouse

Toulouse

    Silver star

  • Members
  • PipPipPip
  • 194 posts
  • LocationUnited States

Posted 13 August 2015 - 11:56 AM

OK - I'm biting the bullet and just doing the liquid suspension to try to get off these last couple of mg.s safely. (i'm down to 2.5 and have shaved off a bit with a razor so I'm not sure exactly where I'm at these last 2 days - 1.75??)  Being that it's hard for me to figure out correctly the dosage I'm at, I ordered, and am getting the Paxil oral suspension - and will try it tomorrow for the first time.

My question is that being on the generic for so long, and switching to the name brand PAXIL - will this effect me negatively? 

 

Also, what kind of syringe should I ask the pharmacist for?

Thanks for your time, and I will post updates on how my final tapering is coming along for any future taperists.

 

 


Been on Paxil 14 years. 40mg for the bulk of those.

20mg in 2014

10mg March of 2015 - then tapered to 5mg

Then to 2.5 to 1.5 - to 1mg, from Mar-August.

As of August 23 2015, I am flying without a net.  Paxil free!

 

WD symptoms since tapering mid- 2015:

 

Short temper, hostile. Mostly early in my withdrawal. Brain zaps. Bruxism. Wild vivid dreams  Hives (chronic that lasted 5 months which diminished after diet changes) Food intolerance (gluten, soy, dairy - eliminating these took away my hives mostly).Lump in throat, . Joint pain. Knees, elbows.  Pain in feet. Numbness in hands. One of my toes. (mostly when I am sleeping, or waking up). Shaking, like I'm cold. Trembling. Tremors, muscle twitches all over. Facial tics. Eye, lips. Head.  Floaters in my eyes. Severe Insomnia (between months 4-5)  then returned from March-October 2016. I'm sleeping better now. Dreams have returned to normal (month 7) High levels of anxiety when around large crowds or in large rooms. Intestinal spasms, heartburn.  Dizzy spells.  Panic/Anxiety Attacks suddenly developed months 8 out. Took Xanax as needed (bad idea, no longer doing).  No xanax at all since June, after bad reaction.  Mindfulness and mediation helped A LOT. Still practicing. I highly recommend.

Slowly feeling better, 14 months off. (11-08-16)

 

 


#25 Toulouse

Toulouse

    Silver star

  • Members
  • PipPipPip
  • 194 posts
  • LocationUnited States

Posted 13 August 2015 - 03:38 PM

Thank you Altostrata - but I also need help figuring out my taper numbers.  10mg = 5ml of the suspension.  Am I just dividing the mg in half to make the ml?


Been on Paxil 14 years. 40mg for the bulk of those.

20mg in 2014

10mg March of 2015 - then tapered to 5mg

Then to 2.5 to 1.5 - to 1mg, from Mar-August.

As of August 23 2015, I am flying without a net.  Paxil free!

 

WD symptoms since tapering mid- 2015:

 

Short temper, hostile. Mostly early in my withdrawal. Brain zaps. Bruxism. Wild vivid dreams  Hives (chronic that lasted 5 months which diminished after diet changes) Food intolerance (gluten, soy, dairy - eliminating these took away my hives mostly).Lump in throat, . Joint pain. Knees, elbows.  Pain in feet. Numbness in hands. One of my toes. (mostly when I am sleeping, or waking up). Shaking, like I'm cold. Trembling. Tremors, muscle twitches all over. Facial tics. Eye, lips. Head.  Floaters in my eyes. Severe Insomnia (between months 4-5)  then returned from March-October 2016. I'm sleeping better now. Dreams have returned to normal (month 7) High levels of anxiety when around large crowds or in large rooms. Intestinal spasms, heartburn.  Dizzy spells.  Panic/Anxiety Attacks suddenly developed months 8 out. Took Xanax as needed (bad idea, no longer doing).  No xanax at all since June, after bad reaction.  Mindfulness and mediation helped A LOT. Still practicing. I highly recommend.

Slowly feeling better, 14 months off. (11-08-16)

 

 


#26 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,887 posts
  • LocationSan Francisco, CA

Posted 14 August 2015 - 09:50 AM

10mg = 5ml means there is 1mg in 0.5mL of the liquid. If you want to take 2.5mg, for example, you would take 1.25mL of the liquid.

 

You can always ask a pharmacist to help you with the calculations.


Edited by Altostrata, 14 August 2015 - 02:46 PM.
corrected math error

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#27 Toulouse

Toulouse

    Silver star

  • Members
  • PipPipPip
  • 194 posts
  • LocationUnited States

Posted 14 August 2015 - 12:37 PM

10mg = 5ml means there is 1mg in 0.5mL of the liquid. If you want to take 2.5mg, for example, you would take 5mL of the liquid.
 
You can always ask a pharmacist to help you with the calculations.


Thank you Alto. My dr helped me figure it out. Basically divide the ml by 2 to get the mg. So 5mg is equal to 2.5ml. 2.5 mg is equal to 1.25ml and so on.

Been on Paxil 14 years. 40mg for the bulk of those.

20mg in 2014

10mg March of 2015 - then tapered to 5mg

Then to 2.5 to 1.5 - to 1mg, from Mar-August.

As of August 23 2015, I am flying without a net.  Paxil free!

 

WD symptoms since tapering mid- 2015:

 

Short temper, hostile. Mostly early in my withdrawal. Brain zaps. Bruxism. Wild vivid dreams  Hives (chronic that lasted 5 months which diminished after diet changes) Food intolerance (gluten, soy, dairy - eliminating these took away my hives mostly).Lump in throat, . Joint pain. Knees, elbows.  Pain in feet. Numbness in hands. One of my toes. (mostly when I am sleeping, or waking up). Shaking, like I'm cold. Trembling. Tremors, muscle twitches all over. Facial tics. Eye, lips. Head.  Floaters in my eyes. Severe Insomnia (between months 4-5)  then returned from March-October 2016. I'm sleeping better now. Dreams have returned to normal (month 7) High levels of anxiety when around large crowds or in large rooms. Intestinal spasms, heartburn.  Dizzy spells.  Panic/Anxiety Attacks suddenly developed months 8 out. Took Xanax as needed (bad idea, no longer doing).  No xanax at all since June, after bad reaction.  Mindfulness and mediation helped A LOT. Still practicing. I highly recommend.

Slowly feeling better, 14 months off. (11-08-16)

 

 


#28 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,887 posts
  • LocationSan Francisco, CA

Posted 14 August 2015 - 02:47 PM

That's correct. I fixed my error.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#29 Rachelina

Rachelina

    Silver star

  • Members
  • PipPipPip
  • 180 posts
  • LocationNew Hampshire

Posted 27 May 2016 - 04:20 AM

Maybe this belongs in an existing topic but I'm not sure which. 

 

I'm not sure how to store my liquid Paxil. I searched online and found the manufacturer's info sheet which says to store below 77 degrees F. But several other sources, such as drugs.com, said to store at room temperature. I also have an ancient (2008) bottle of liquid Paxil that says store between 65 and 77 degrees. 

 

I don't have air conditioning and it's starting to get hot, so the only option to keep it below 77 degrees is the fridge. But with all the conflicting information I'm not sure if this is OK.  I did stick it in the fridge yesterday when I saw the thermostat had reached 77. But when I researched further and saw several sources saying room temperature, I pulled it out (since by that time the temperature had gone down). Now I'm afraid I wrecked it somehow by putting it in the fridge. 

 

Last summer I didn't even think about this and kept it in my room, where I'm sure the temperature got into the 90's frequently. Sometimes I wonder if this could have played a part in the crash I had starting in November. Probably not, because that would be quite a delayed reaction, and usually I feel it sooner if there is some big change. But to be on the safe side I want to pay attention to proper storage. Any advice welcome!


Edited by KarenB, 22 July 2016 - 01:37 AM.
merged similar topics

Trying to get off Paxil since 2007. Was tapering by 0.1 mg every 4-5 weeks. Had awful crash in November 2015 at .5 mg; updosed gradually to 2 mg. 

 

Doing better and tapering again, much slower this time. 3/2/16 dropped to 1.96 mg, 4/19 1.9 mg, 6/20 1.82 mg, 8/17 1.74 mg, 10/19 1.7 mg, 11/21 1.66 mg, 12/21 1.62 mg, 1/21 1.58 mg, 2/21 1.54 mg, 3/23 1.5 mg

 

Taking Klonopin daily since November 2015 to deal with crash. 1/10/16 started milk titration taper from .5 mg. 3/23/17 .076 mg


#30 SquirrellyGirl

SquirrellyGirl

    Gold star

  • Moderators
  • 1,347 posts
  • Locationnear Fresno, CA

Posted 27 May 2016 - 10:55 AM

Hmm, I don't have an obvious answer for you, other than to perhaps ask a pharmacist about the best approach...You get into the 90's in New Hampshire?  I had no idea!  I know that probably includes humidity in your neck of the woods!  We get triple digits here but usually dry.

 

SG


Prozac 1995-1999, don't remember the dosage; Wellbutrin 1999-2002? Don't remember dosage though it was in the 300 mgs range
Effexor XR 2002-2014 up to 225 mg at one point, down to 37.5 mg towards end but back up to 75 mg in 2014; now realize I had W/D as I dropped down, memory very poor about history.  Did fast taper, don't remember details, around August 2014.
Took Sam-E 200 mg AM and 500 mg L-tryptophan PM Sept.2014 to January 2015

Doing poorly, put on Viibryd 10 mg for 1 wk, 20 mg for several days, BAD ANXIETY, fast taper to 0 in a week; back on Sam-E 200 mg AM and L-tryptophan 500 mg PM until April 10, 2015; doing very badly, put on Remeron 7.5 mg start April 15-April 30, 2015; Increased Remeron from 7.5 mg/day to 37.5 mg by May 22, 2015; still doing very badly,

June 1 Reinstated Effexor XR 37.5 mg, Remeron dropped to 30 mg PM. Immediate relief of symptoms, like nothing had ever happened!  On p-doc's orders went up to 75 mg Effexor June 11-12, then back to 37.5 mg when I realized all the hell I had been through before was WD from Effexor!  Joined SA and began tapering both too soon one month later.

8/22/15: Effexor to 30.75 mg, Remeron to 22 mg. 9/9/15 Effexor 30 mg/Remeron 21 mg. 9/24/15: Remeron 19 mg. 10/25/16: Remeron 17 mg. 11/14/15:  Effexor 28.5 mg 12/2/15: Remeron 16 mg. 12/5/15: Effexor 28.1 mg. 12/17/15: Remeron 15 mg. 1/26/16: Remeron 14 mg. 3/22/16, Remeron 13.5 mg and Effexor 25.9 mg (had nudged it down by fraction of a mg since Dec).  4/28/16: Remeron 13 mg, Effexor 25.5 mg.  5/21/16: Remeron 12 mg, Effexor 24.75 mg.  6/17/16, Effexor 23.25 mg, Remeron 11.6 mg. 7/12/16:  Remeron 11 mg, Effexor 22.12 mg.  9/22/16:  Effexor 19.5 mg, Remeron 9 mg

 

My intro: http://survivinganti...e-2#entry196679

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.


#31 Rachelina

Rachelina

    Silver star

  • Members
  • PipPipPip
  • 180 posts
  • LocationNew Hampshire

Posted 27 May 2016 - 04:37 PM

Thanks Squirrelly Girl! Yes it gets into the 90's, not quite often enough to be worth buying an air conditioner, but still too often for me! And yes the humidity is awful too. I'll ask the pharmacist I guess, but I'm also curious how other people store their liquid. And how important it is not to go above 77 at all. At least I have it downstairs now which is cooler than my bedroom and cooler than outside, but it's still going to get into the 80's sometimes. 


Trying to get off Paxil since 2007. Was tapering by 0.1 mg every 4-5 weeks. Had awful crash in November 2015 at .5 mg; updosed gradually to 2 mg. 

 

Doing better and tapering again, much slower this time. 3/2/16 dropped to 1.96 mg, 4/19 1.9 mg, 6/20 1.82 mg, 8/17 1.74 mg, 10/19 1.7 mg, 11/21 1.66 mg, 12/21 1.62 mg, 1/21 1.58 mg, 2/21 1.54 mg, 3/23 1.5 mg

 

Taking Klonopin daily since November 2015 to deal with crash. 1/10/16 started milk titration taper from .5 mg. 3/23/17 .076 mg


#32 ChessieCat

ChessieCat

    Platinum star

  • Moderators
  • 2,823 posts
  • LocationSydney Australia

Posted 27 May 2016 - 06:12 PM

Just did a search and found this:

 

https://www.apotex.c...il_irtb_ins.pdf

 

How should I store PAXIL?
Store PAXIL Tablets at room temperature between 59º and 86ºF (15º and 30ºC).
Store PAXIL Oral Suspension at or below 77ºF (25ºC).
Keep PAXIL away from light.
Keep bottle of PAXIL closed tightly.

 

I imagine if it it was not to be stored in the refrigerator it would be stated, especially since the tablet temp is stated as "between".

 

But yes, you could check with the pharmacist or ring the number on the sheet:  For more information about PAXIL call 1-800-706-5575.


Podcasts:    Let's Talk Withdrawal

 

Antidepressants:  25 years - 1 unknown, Prozac (caused muscle weakness), Zoloft; Cipramil CTed (very sick for 2.5 wks soon after)

Pristiq:  50mg mid 2012, 100mg beg 2014 (mild Serotonin Toxicity)     Current:  Pristiq 28mg (from 3 March 17)

 

Tapering history & graph

My website - includes my brief history + links to videos & information on the web

 

I've still got a way to go ... but I've already come a long way!!!

 

PLEASE NOTE:  I am not a medical professional.


#33 ChessieCat

ChessieCat

    Platinum star

  • Moderators
  • 2,823 posts
  • LocationSydney Australia

Posted 04 September 2016 - 02:33 PM

Paxil Monograph 2014


Podcasts:    Let's Talk Withdrawal

 

Antidepressants:  25 years - 1 unknown, Prozac (caused muscle weakness), Zoloft; Cipramil CTed (very sick for 2.5 wks soon after)

Pristiq:  50mg mid 2012, 100mg beg 2014 (mild Serotonin Toxicity)     Current:  Pristiq 28mg (from 3 March 17)

 

Tapering history & graph

My website - includes my brief history + links to videos & information on the web

 

I've still got a way to go ... but I've already come a long way!!!

 

PLEASE NOTE:  I am not a medical professional.


#34 snostorm

snostorm

    Member

  • Members
  • PipPip
  • 77 posts
  • LocationLong Island NY

Posted 28 January 2017 - 06:29 AM

This medication should be illegal.  I would have NEVER went on this medication had I known what I was in store for.  I started this medication in 2002.  The makers of this drug should be made to pay for all the people they got hooked on this drug.  


May 2016 17.5mg Paxil from 20mg

June 2016 10mg Paxil

October 2016 7,5 mg Paxil

November 2016 5 mg Paxil

December switched to liquid paxil 5 mg

Mid December 2.5 mg Paxil

January 2.2 mg Paxil

Feb 5th 2016 updose to 5mg Paxil tablet Prevacid OTC long term 15mg daily

February 26th updose to 7.5mg Paxil