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Tips for tapering off stomach acid blockers or PPIs (esomeprazole, lansoprazole, omeprazole)


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#37 blackrabbit

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Posted 17 February 2016 - 02:26 PM

blackrabbit, please read this topic from the beginning.

I did but my question was not answered so I wanted to see if anyone could give me advice.


Current meds: Escitalopram

Was put on 20mg Lexapro for 4 years; was at 18mg for ~1 week.

4/19/15: 15mg; WD symptoms include: loss of appetite, weight loss, nausea and indigestion after eating, diarrhea, and anxiety. Most of these happen at night.

6/5/15: 13mg; WD symptoms include: tiredness/lightheadedness, indigestion, numbness (emotionally)

7/6/15: 11mg --> 7/10/14: 11.7mg (wanted to taper by 10%)

8/10/15: 10mg; WD symptoms include: anxiety, nausea, GI upset, headaches

9/1/15: bumped back to 10.5mg (back to tapering by 10%); 10/5/15: back to 10mg

11/8: down to 9mg: feeling depressed so far ---> 11/16: bumped back to 10mg :(

1/23: back to 9mg; headaches, "motion sickness" feeling, anxiety

3/24: 8.5mg; 5/24: 8mg; nausea and dizziness bumped back to 8.5mg 3/26 :(

 

blog: https://offwithyourmeds.wordpress.com


#38 Petunia

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Posted 17 February 2016 - 02:56 PM

Taperinq required to prevent rebound reflux

To prevent rebound reflux, taper off an acid blocker as soon as possible. As a medical non-professional, my guess of a good rate is 25% per week. If you get rebound reflux, lower the decrease and take longer to taper off.


Acid-suppressing drugs such as esomeprazole (Nexium), lansoprazole (Prevacid) and omeprazole (Prilosec) may trigger rebound hyperacidity and reflux if they are stopped abruptly.

 


I'm not a doctor.  My comments are not medical advise. These are my opinions based on my own experience and what I've learned. Please discuss your situation with a medical practitioner who has knowledge of tapering and withdrawal...if you are lucky enough to find one.

 

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#39 Prozac20

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Posted 06 May 2016 - 01:11 PM

I had been prescribed omeprazole 40mg prior to my experience with Prozac . Now , I'm don't know if taking it while going through withdrawal is better to deal with symptoms or not being that omeprazole has a few side effects on its own . Anyone taking acid reflux medication like omeprazole or Nexium ?
Xanax PRN ( 1/2 of .25mg approximately 2-3 a month when needed ) since May 2015
In April 2016 started birth control and in my opinion it triggered anxiety for almost a week straight and took 1/2 .25mg Xanax everyday for that week ( never had taken that many in a row before )
Saw the family MD and gave me Prozac 20 mg.
took it for 6 days and could not handle the side effects and had to stop working
Went back to the dr on the 7 day and told me to stop CT . I told him that I was scared to stop so suddenly so he gave me 10mg to take to see if the side effects decreased
Took the 10mg that night and the next day felt so much worse . After that did take anything any more except and antibiotic due to UTI
It's been almost 7 weeks and I have a lot of weakness ( comes and goes) anxiety , cortisol urges at night and worse in the morning which usually lessens throughout the day , tinnitus , heavy leg feeling , fatigue and burning skin mostly my left arm, face and neck mainly when I fee the cortisol surges .

#40 Mort81

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Posted 07 May 2016 - 12:52 AM

Ya this drug has been extremely difficult to kick for me during WD.  I have been on it for awhile.   So the rebound acid is bad. But  one of my toughest WD symptom has been stomach pain . So an change in my regiman affects my gut alot. I weened from 60mg-30mg . . than had 2 months of bad acid. until it leveled out.  Than I weened from 30mg-20mg. But at 20mg I started having lots of problems. So For me its a sign my system isnt strong enough to handle the rebound yet. So i am back at 30mg . I am on Dexilant. I have a really good diet so it bugs me that I know  I dont need the pills what so ever .  I only need it because im addicted to them. Id say if you can taper off it slowly and your system is okay , than Id stay off it. It wont help your recovery.  Its a bad drug ... but if the rebound acid is hurting too much and causing other symptms to be worse than maybe wait until you are strong enough to taper off it.   If you can be on the lowest possible dose that doesnt cause the rebound symptoms.


Was on 30mg (Lexapro) for 7-8yrs20mg for 3 months (This was my choice my Doc wanted me to drop much faster)15 mg 2week10mg 2 weeks 5 mg 1 week0 since August 24th Clonazapam. Currently 0.10mg daily. PPI Dexlant 20-30mg for last 29 months currently at 30mg

#41 Altostrata

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Posted 07 May 2016 - 12:36 PM

Mort, sometimes the indigestion is caused by a class of food, such as dairy or nightshades. Have you tried systematically excluding different kinds of foods.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

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#42 Mort81

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Posted 08 May 2016 - 02:20 AM

Thanks for the response Alto, yes I have eliminated dairy and anything that could cause this. For the last few weeks ive only been to eat one meal a day .  Its always a plain healthy meal . For me my waves many of them have been an increase of distress in the gut no matter the diet.   ill ride it out , hopefully it passes  soon and I can resume my 2 meals a day.  My weight has dropped 10 in the last month. 


Was on 30mg (Lexapro) for 7-8yrs20mg for 3 months (This was my choice my Doc wanted me to drop much faster)15 mg 2week10mg 2 weeks 5 mg 1 week0 since August 24th Clonazapam. Currently 0.10mg daily. PPI Dexlant 20-30mg for last 29 months currently at 30mg

#43 btdt

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Posted 14 May 2016 - 05:13 PM

I had been prescribed omeprazole 40mg prior to my experience with Prozac . Now , I'm don't know if taking it while going through withdrawal is better to deal with symptoms or not being that omeprazole has a few side effects on its own . Anyone taking acid reflux medication like 

“PPIs,” whose Product information (PI) warns against their use in conjunction with drugs metabolized by CYP450 2C19

https://www.tga.gov....nde-lucire2.pdf

 

There is a thread here called how to taper off ppi drugs... 

peace


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

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#44 Frogie

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Posted 07 September 2016 - 10:44 AM

Hi Lili,
One more time, I realigned how similar our med history on both PPI and AD, including timing!
Ironically, after taking 16 yrs proacid 15 mg, my doctor suggest me to switch to antacid. I did about 3 weeks ago and that was when I started seeing lights with my WD symptoms. It made me wondering if PPI is somehow part of the reason of the Wd.
I just read this topic today. Hope sudden stop of the PPI won't cause me any future problem. I'm good so far with the prescribed antacid.


I have been on omeprazole for about 15 years. I had rebound reflux on the 1st 25% cut. I've stayed there for 2 weeks now and am feeling better. How long did you have rebound acid and what did you do for it? As soon as I'm done with this I'm starting Zantac then back to my Lexapro. Thanks in advance for answering my question!
PREVIOUS medications and discontinuations: Zoloft, 1997-1999; switch to Paxil, 1999-2002 ___2009 - 2015: Gabapentin, 900mg, 2010-2015: tapered of 9 weeks, last dose Sept. 2015, no symptoms ___ Lamictal, 300mg, 2009-2015, taper of 6 weeks, last dose Oct 2015,no symptoms ___ Valium, 40mg, 2008-2015, 8 week taper, last dose Dec 2015, no symptoms ___ 2016: Carafate 1mg (anti-ulcer med) 4x a day as needed. Prescribed but not taking it. ___ Prilosec 40mg; 28-Aug started 25% taper; 1-Oct 20mg a.m. + 15mg p.m. Stopped Nov 26, 2016 w/rebound acid but not too bad.---CURRENT MEDICATIONS---Supplements: 150 mg Mag chloride, 350mg Krill Oil, Milk Thistle, ProbioticFor nausea as needed: Zantac, 300mg only "as needed". Zofran 4mg for nausea; only take it when nausea is unbearable or phenegran.Xanax, 3 mg in 4 split doses, 2008-present Lexpro: 2002 - March 2016: 20 mg; Mar-Apr 2016: 8 week taper 20 mg - 10 mg; 8-June 9mg; 13-June 10 mg; 11-Sep 7.5 mg; 25-Sep 5 mg; 5-Oct 10mg; started taking Liquid Lexapro in Nov 2016; started taper with liquid 1-Jan-17 9mg; 22-Jan 8.1mg; 22-Feb 7.3 mg, (horrible nausea); 30-Mar, updosed to 7.6 (1st morning, not as much nausea, hopefully it will get better); nausea was brutal; 6-April, updosed to 7.9mg, hoping nausea will let up; nausea stopped on 14-April for 2 days so far; 17-April nausea started back up :( stopped supplements on 10-April

Levothyroxine
50mcg 18-April for hypothydroidism Stopped by dr. on 20-April too many side effects, going to try again in 6 months

#45 Lois

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Posted 27 September 2016 - 04:27 AM

I am new here and hoping someone has some insights.

I have been on lexapro 10mg for 12 years and was bumped up to 15mg 2 years ago. In the mean time I was put on the ppi Protonix 2 years ago as well. I have been weaning off the Ppi over the past 3 weeks and I think it's having an effect on my absorption of lexapro. I haven't changed my dose of lexapro but I feel like I'm in WD!

I have read that ppis have an effect on the serum levels of SSRIS basically increasing the serum levels. And now that I'm weaning off the PPI I'm in effect lowering the serum levels of lexapro. Make any sense?

Help
Lexapro started 2004. In 2014 upped dosage to 15mg when my mom passed and then started Protonix a PPI. So been on the PPI and the increased dose of lexapro for two years. This November 2016 decided to drop lexapro back to 10mg and stopped taking ppi because I felt like I had some seratonin syndrome like symyptoms (not sure). Doc wasn't sure either. Trying to get through this...

#46 Frogie

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Posted 27 September 2016 - 05:12 AM

I am new here and hoping someone has some insights.
I have been on lexapro 10mg for 12 years and was bumped up to 15mg 2 years ago. In the mean time I was put on the ppi Protonix 2 years ago as well. I have been weaning off the Ppi over the past 3 weeks and I think it's having an effect on my absorption of lexapro. I haven't changed my dose of lexapro but I feel like I'm in WD!
I have read that ppis have an effect on the serum levels of SSRIS basically increasing the serum levels. And now that I'm weaning off the PPI I'm in effect lowering the serum levels of lexapro. Make any sense?
Help

 

 

I did it backwards until I found this site. I was going off Lexapro 1st. I had already cut my Lexapro in 1/2. I am now on my 3rd week of weaning off the Prilosec and I definitely feel like I'm going through withdrawals from Lexapro. I'm sick to my stomach, and have a lot of intestinal issues going on. I know exactly how you feel. If you need to, slow down on your taper of protonix, and maybe that will help. That's what they told me on here. If I get rebound, to taper slower. I hope that helps. Let's keep in contact since we are going through the same thing. :)


PREVIOUS medications and discontinuations: Zoloft, 1997-1999; switch to Paxil, 1999-2002 ___2009 - 2015: Gabapentin, 900mg, 2010-2015: tapered of 9 weeks, last dose Sept. 2015, no symptoms ___ Lamictal, 300mg, 2009-2015, taper of 6 weeks, last dose Oct 2015,no symptoms ___ Valium, 40mg, 2008-2015, 8 week taper, last dose Dec 2015, no symptoms ___ 2016: Carafate 1mg (anti-ulcer med) 4x a day as needed. Prescribed but not taking it. ___ Prilosec 40mg; 28-Aug started 25% taper; 1-Oct 20mg a.m. + 15mg p.m. Stopped Nov 26, 2016 w/rebound acid but not too bad.---CURRENT MEDICATIONS---Supplements: 150 mg Mag chloride, 350mg Krill Oil, Milk Thistle, ProbioticFor nausea as needed: Zantac, 300mg only "as needed". Zofran 4mg for nausea; only take it when nausea is unbearable or phenegran.Xanax, 3 mg in 4 split doses, 2008-present Lexpro: 2002 - March 2016: 20 mg; Mar-Apr 2016: 8 week taper 20 mg - 10 mg; 8-June 9mg; 13-June 10 mg; 11-Sep 7.5 mg; 25-Sep 5 mg; 5-Oct 10mg; started taking Liquid Lexapro in Nov 2016; started taper with liquid 1-Jan-17 9mg; 22-Jan 8.1mg; 22-Feb 7.3 mg, (horrible nausea); 30-Mar, updosed to 7.6 (1st morning, not as much nausea, hopefully it will get better); nausea was brutal; 6-April, updosed to 7.9mg, hoping nausea will let up; nausea stopped on 14-April for 2 days so far; 17-April nausea started back up :( stopped supplements on 10-April

Levothyroxine
50mcg 18-April for hypothydroidism Stopped by dr. on 20-April too many side effects, going to try again in 6 months

#47 scallywag

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Posted 27 September 2016 - 09:04 AM

Lois -- Welcome to Surviving Antidepressants (SA). Please start a topic in the Introductions forum so that we can get to know you and answer your questions.

Link to creating a new topic in Introductions


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.
1997-1999 Effexor; 2002-2005 Effexor XR 37.5 mg linear taper, dropping same #beads/week with bad results
Cymbalta (brand name), 60 mg 2012 - 2015; 20 mg to 7 mg in 2016, exact doses and dates in this post;
2017: 6.3 (58 beads) Feb. 1; 5.6 mg (52) Feb. 22; 5.4 mg (50) Mar. 15; 5.1 mg (47) Mar. 25; 4.9 mg (45) Apr. 5; 4.5 mg (42) Apr. 14; 3.5 mg (32) Apr. 26;
Current dose: 2.6 mg (24) 2017-May-17
+ Supplements: fish oil (1500 mg EPA/500 mg DHA), Vitamins: D3, K2, C; Minerals: Mg, Se, Cr, I, V
scallywag's Introduction
Online spreadsheet for dose taper calculations and nz11's THE WORKS spreadsheet


#48 Frogie

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Posted 27 September 2016 - 09:20 AM

Lois -- Welcome to Surviving Antidepressants (SA). Please start a topic in the Introductions forum so that we can get to know you and answer your questions.
Link to creating a new topic in Introductions


I hope I answered Lois as best as I could, with the information you helped me with. I'm on my last week of Prilosec and then we will see if I get rebound acid. I'm prepared with DGL and Maalox. Then on with the Lexapro!
PREVIOUS medications and discontinuations: Zoloft, 1997-1999; switch to Paxil, 1999-2002 ___2009 - 2015: Gabapentin, 900mg, 2010-2015: tapered of 9 weeks, last dose Sept. 2015, no symptoms ___ Lamictal, 300mg, 2009-2015, taper of 6 weeks, last dose Oct 2015,no symptoms ___ Valium, 40mg, 2008-2015, 8 week taper, last dose Dec 2015, no symptoms ___ 2016: Carafate 1mg (anti-ulcer med) 4x a day as needed. Prescribed but not taking it. ___ Prilosec 40mg; 28-Aug started 25% taper; 1-Oct 20mg a.m. + 15mg p.m. Stopped Nov 26, 2016 w/rebound acid but not too bad.---CURRENT MEDICATIONS---Supplements: 150 mg Mag chloride, 350mg Krill Oil, Milk Thistle, ProbioticFor nausea as needed: Zantac, 300mg only "as needed". Zofran 4mg for nausea; only take it when nausea is unbearable or phenegran.Xanax, 3 mg in 4 split doses, 2008-present Lexpro: 2002 - March 2016: 20 mg; Mar-Apr 2016: 8 week taper 20 mg - 10 mg; 8-June 9mg; 13-June 10 mg; 11-Sep 7.5 mg; 25-Sep 5 mg; 5-Oct 10mg; started taking Liquid Lexapro in Nov 2016; started taper with liquid 1-Jan-17 9mg; 22-Jan 8.1mg; 22-Feb 7.3 mg, (horrible nausea); 30-Mar, updosed to 7.6 (1st morning, not as much nausea, hopefully it will get better); nausea was brutal; 6-April, updosed to 7.9mg, hoping nausea will let up; nausea stopped on 14-April for 2 days so far; 17-April nausea started back up :( stopped supplements on 10-April

Levothyroxine
50mcg 18-April for hypothydroidism Stopped by dr. on 20-April too many side effects, going to try again in 6 months

#49 Cheri

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Posted 27 September 2016 - 09:20 AM

It's amazing to discover so many side effects to antidepressants. Having GERD may be one of them. After recently reading about kidney issues (just discovered!), I'm determined to taper off my prescription. I'm wondering if I should do a concurrent taper of Pantoprazole 40 mg and Celexa 20 mg at same time.

Thoughts?

#50 Frogie

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Posted 27 September 2016 - 10:01 AM

It's amazing to discover so many side effects to antidepressants. Having GERD may be one of them. After recently reading about kidney issues (just discovered!), I'm determined to taper off my prescription. I'm wondering if I should do a concurrent taper of Pantoprazole 40 mg and Celexa 20 mg at same time.
Thoughts?


I was told by Altostrata to taper off Prilosec, Zantac, Lexapro and then Xanax. One at a time. This is my last week for Prilosec, I'm already off Zantac, except as needed, then I can get off Lexapro. I think I'll hold a little while on the Xanax before getting off everything at once. I just went off 3 meds last year between September and December. I'm just soooooooo afraid of rebound acid, but I have DGL and Maalox standing by. The dr also gave me zofran, but that is something else you have to wean off of. I'm having liver problems, so I have good days and bad days, but I'm doing everything I can to get off the meds without too many problems. The moderators on here are really good. Keep me posted on how you are doing. :)
PREVIOUS medications and discontinuations: Zoloft, 1997-1999; switch to Paxil, 1999-2002 ___2009 - 2015: Gabapentin, 900mg, 2010-2015: tapered of 9 weeks, last dose Sept. 2015, no symptoms ___ Lamictal, 300mg, 2009-2015, taper of 6 weeks, last dose Oct 2015,no symptoms ___ Valium, 40mg, 2008-2015, 8 week taper, last dose Dec 2015, no symptoms ___ 2016: Carafate 1mg (anti-ulcer med) 4x a day as needed. Prescribed but not taking it. ___ Prilosec 40mg; 28-Aug started 25% taper; 1-Oct 20mg a.m. + 15mg p.m. Stopped Nov 26, 2016 w/rebound acid but not too bad.---CURRENT MEDICATIONS---Supplements: 150 mg Mag chloride, 350mg Krill Oil, Milk Thistle, ProbioticFor nausea as needed: Zantac, 300mg only "as needed". Zofran 4mg for nausea; only take it when nausea is unbearable or phenegran.Xanax, 3 mg in 4 split doses, 2008-present Lexpro: 2002 - March 2016: 20 mg; Mar-Apr 2016: 8 week taper 20 mg - 10 mg; 8-June 9mg; 13-June 10 mg; 11-Sep 7.5 mg; 25-Sep 5 mg; 5-Oct 10mg; started taking Liquid Lexapro in Nov 2016; started taper with liquid 1-Jan-17 9mg; 22-Jan 8.1mg; 22-Feb 7.3 mg, (horrible nausea); 30-Mar, updosed to 7.6 (1st morning, not as much nausea, hopefully it will get better); nausea was brutal; 6-April, updosed to 7.9mg, hoping nausea will let up; nausea stopped on 14-April for 2 days so far; 17-April nausea started back up :( stopped supplements on 10-April

Levothyroxine
50mcg 18-April for hypothydroidism Stopped by dr. on 20-April too many side effects, going to try again in 6 months

#51 Frogie

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Posted 09 October 2016 - 11:24 AM

It's amazing to discover so many side effects to antidepressants. Having GERD may be one of them. After recently reading about kidney issues (just discovered!), I'm determined to taper off my prescription. I'm wondering if I should do a concurrent taper of Pantoprazole 40 mg and Celexa 20 mg at same time.

Thoughts?

How are you feeling?


PREVIOUS medications and discontinuations: Zoloft, 1997-1999; switch to Paxil, 1999-2002 ___2009 - 2015: Gabapentin, 900mg, 2010-2015: tapered of 9 weeks, last dose Sept. 2015, no symptoms ___ Lamictal, 300mg, 2009-2015, taper of 6 weeks, last dose Oct 2015,no symptoms ___ Valium, 40mg, 2008-2015, 8 week taper, last dose Dec 2015, no symptoms ___ 2016: Carafate 1mg (anti-ulcer med) 4x a day as needed. Prescribed but not taking it. ___ Prilosec 40mg; 28-Aug started 25% taper; 1-Oct 20mg a.m. + 15mg p.m. Stopped Nov 26, 2016 w/rebound acid but not too bad.---CURRENT MEDICATIONS---Supplements: 150 mg Mag chloride, 350mg Krill Oil, Milk Thistle, ProbioticFor nausea as needed: Zantac, 300mg only "as needed". Zofran 4mg for nausea; only take it when nausea is unbearable or phenegran.Xanax, 3 mg in 4 split doses, 2008-present Lexpro: 2002 - March 2016: 20 mg; Mar-Apr 2016: 8 week taper 20 mg - 10 mg; 8-June 9mg; 13-June 10 mg; 11-Sep 7.5 mg; 25-Sep 5 mg; 5-Oct 10mg; started taking Liquid Lexapro in Nov 2016; started taper with liquid 1-Jan-17 9mg; 22-Jan 8.1mg; 22-Feb 7.3 mg, (horrible nausea); 30-Mar, updosed to 7.6 (1st morning, not as much nausea, hopefully it will get better); nausea was brutal; 6-April, updosed to 7.9mg, hoping nausea will let up; nausea stopped on 14-April for 2 days so far; 17-April nausea started back up :( stopped supplements on 10-April

Levothyroxine
50mcg 18-April for hypothydroidism Stopped by dr. on 20-April too many side effects, going to try again in 6 months

#52 Altostrata

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Posted 10 October 2016 - 01:26 PM

Cherie, please do not change dosage of two drugs at the same time.

 

Please post your question in your Introductions topic as the answer will take this topic off-topic.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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#53 Frogie

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Posted 13 October 2016 - 06:38 AM

Hi Lili,
One more time, I realigned how similar our med history on both PPI and AD, including timing!
Ironically, after taking 16 yrs proacid 15 mg, my doctor suggest me to switch to antacid. I did about 3 weeks ago and that was when I started seeing lights with my WD symptoms. It made me wondering if PPI is somehow part of the reason of the Wd.
I just read this topic today. Hope sudden stop of the PPI won't cause me any future problem. I'm good so far with the prescribed antacid.


When you stopped your PPI were you nauseous? If so, how long?

Thanks...
PREVIOUS medications and discontinuations: Zoloft, 1997-1999; switch to Paxil, 1999-2002 ___2009 - 2015: Gabapentin, 900mg, 2010-2015: tapered of 9 weeks, last dose Sept. 2015, no symptoms ___ Lamictal, 300mg, 2009-2015, taper of 6 weeks, last dose Oct 2015,no symptoms ___ Valium, 40mg, 2008-2015, 8 week taper, last dose Dec 2015, no symptoms ___ 2016: Carafate 1mg (anti-ulcer med) 4x a day as needed. Prescribed but not taking it. ___ Prilosec 40mg; 28-Aug started 25% taper; 1-Oct 20mg a.m. + 15mg p.m. Stopped Nov 26, 2016 w/rebound acid but not too bad.---CURRENT MEDICATIONS---Supplements: 150 mg Mag chloride, 350mg Krill Oil, Milk Thistle, ProbioticFor nausea as needed: Zantac, 300mg only "as needed". Zofran 4mg for nausea; only take it when nausea is unbearable or phenegran.Xanax, 3 mg in 4 split doses, 2008-present Lexpro: 2002 - March 2016: 20 mg; Mar-Apr 2016: 8 week taper 20 mg - 10 mg; 8-June 9mg; 13-June 10 mg; 11-Sep 7.5 mg; 25-Sep 5 mg; 5-Oct 10mg; started taking Liquid Lexapro in Nov 2016; started taper with liquid 1-Jan-17 9mg; 22-Jan 8.1mg; 22-Feb 7.3 mg, (horrible nausea); 30-Mar, updosed to 7.6 (1st morning, not as much nausea, hopefully it will get better); nausea was brutal; 6-April, updosed to 7.9mg, hoping nausea will let up; nausea stopped on 14-April for 2 days so far; 17-April nausea started back up :( stopped supplements on 10-April

Levothyroxine
50mcg 18-April for hypothydroidism Stopped by dr. on 20-April too many side effects, going to try again in 6 months

#54 LexAnger

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Posted 13 October 2016 - 11:49 AM

Hi Lili,
One more time, I realigned how similar our med history on both PPI and AD, including timing!
Ironically, after taking 16 yrs proacid 15 mg, my doctor suggest me to switch to antacid. I did about 3 weeks ago and that was when I started seeing lights with my WD symptoms. It made me wondering if PPI is somehow part of the reason of the Wd.
I just read this topic today. Hope sudden stop of the PPI won't cause me any future problem. I'm good so far with the prescribed antacid.


When you stopped your PPI were you nauseous? If so, how long?
Thanks...

Not nausea, but my typical WD symptoms, super dizzy, head pressure on the same day I stopped antacid. I was freaking out so updose lexapro from 2.7 to 3.7, feeling great for 1 week then all the symptoms back again, so updose again to 4.5 lex. All the hell broke since then experiencing severe drug reaction and WD. Been tapering since then getting worse each day.
<p>2009 Mar.: lexapro 10mg for headache for 2 weeks.2009-2012: on and off 1/4 to 1/3 of 10mg2012 June--2013 Jan,: 1/4-1/3 of 10mg generic, bad jaw pain2013 Jan-Mar: 10 mg generic. severe jaw and head pain; Mar--Aug. started tapering (liquid ever since) from 10 to 5 (one step) then gradually down to 2.25 mg, first ever panic attack, severe head/jaw pain2013 Aug.: back to 2.75 mg; Nov: back to Brand Lex. 2.75mg -- 3mg, slight improvement with pain2014 June: stopped PPI, head pressure/numbness. up-dosed 4.5mg, severe reaction mental symptoms added on2014 Aug--2015 Aug: Micro taper down to 3.2mg, .025mg (<1%) cut holding 2-3 weeks.2015 Aug 15th, Accidental one dose of 4.2mg. worsening brain non-functional, swollen head, body, coma like, DR2016 Feb., started fast taper for the drug toxicity caused by the one dose of 4.2mg, dosing 10am through 11 pm everyday2/13--3.2mg, 3/15-- 2.9mg, 4/19-- 2.6mg, 6/26--2.2mg, 7/22 --1.9mg, 8/16--1.8mg,8/31--1.7m g, 9/13--1.6mg, 9/27--1.5mg, 10/8--1.4mg, 10/14--1.3mg, 11/1--1.2mg, 11/29--1.1mg, 12/12--1mg, 12/22--0.9mg2017: 1/7--0.8mg, 1/15--0.7mg, 1/17--0.6mg, 1/20--0.52, 1/21--0.4mg, 1/22--0.26, 1/23--0.2, sliding Down to 0.13mg by 2/13, then 0.07mg since 2/18, 0.06mg 2/20-3/17, 0.13mg 3/18

#55 Frogie

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Posted 13 October 2016 - 03:38 PM

Hi Lili,
One more time, I realigned how similar our med history on both PPI and AD, including timing!
Ironically, after taking 16 yrs proacid 15 mg, my doctor suggest me to switch to antacid. I did about 3 weeks ago and that was when I started seeing lights with my WD symptoms. It made me wondering if PPI is somehow part of the reason of the Wd.
I just read this topic today. Hope sudden stop of the PPI won't cause me any future problem. I'm good so far with the prescribed antacid.


When you stopped your PPI were you nauseous? If so, how long?
Thanks...

Not nausea, but my typical WD symptoms, super dizzy, head pressure on the same day I stopped antacid. I was freaking out so updose lexapro from 2.7 to 3.7, feeling great for 1 week then all the symptoms back again, so updose again to 4.5 lex. All the hell broke since then experiencing severe drug reaction and WD. Been tapering since then getting worse each day.

I have been really nauseous since I started tapering omeprazole. It's not GERD. It's like I have the stomach flu. I bought some apple cider vinegar today. I'm going to try that and see if it works. Otherwise I'm loaded up with Gaviscon, Maalox, antacids and DGL. I have some Zantac and took 1 today and it helped a lot. But I've already stopped taking it. Was really easy to taper off of that. I don't want to go back on it. I hope the apple cider vinegar works. I've got to get off the omeprazole before I can start my Lexapro taper. Thanks for answering me.
Good luck to you!
PREVIOUS medications and discontinuations: Zoloft, 1997-1999; switch to Paxil, 1999-2002 ___2009 - 2015: Gabapentin, 900mg, 2010-2015: tapered of 9 weeks, last dose Sept. 2015, no symptoms ___ Lamictal, 300mg, 2009-2015, taper of 6 weeks, last dose Oct 2015,no symptoms ___ Valium, 40mg, 2008-2015, 8 week taper, last dose Dec 2015, no symptoms ___ 2016: Carafate 1mg (anti-ulcer med) 4x a day as needed. Prescribed but not taking it. ___ Prilosec 40mg; 28-Aug started 25% taper; 1-Oct 20mg a.m. + 15mg p.m. Stopped Nov 26, 2016 w/rebound acid but not too bad.---CURRENT MEDICATIONS---Supplements: 150 mg Mag chloride, 350mg Krill Oil, Milk Thistle, ProbioticFor nausea as needed: Zantac, 300mg only "as needed". Zofran 4mg for nausea; only take it when nausea is unbearable or phenegran.Xanax, 3 mg in 4 split doses, 2008-present Lexpro: 2002 - March 2016: 20 mg; Mar-Apr 2016: 8 week taper 20 mg - 10 mg; 8-June 9mg; 13-June 10 mg; 11-Sep 7.5 mg; 25-Sep 5 mg; 5-Oct 10mg; started taking Liquid Lexapro in Nov 2016; started taper with liquid 1-Jan-17 9mg; 22-Jan 8.1mg; 22-Feb 7.3 mg, (horrible nausea); 30-Mar, updosed to 7.6 (1st morning, not as much nausea, hopefully it will get better); nausea was brutal; 6-April, updosed to 7.9mg, hoping nausea will let up; nausea stopped on 14-April for 2 days so far; 17-April nausea started back up :( stopped supplements on 10-April

Levothyroxine
50mcg 18-April for hypothydroidism Stopped by dr. on 20-April too many side effects, going to try again in 6 months

#56 Frogie

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Posted 14 October 2016 - 04:35 AM

Has anyone tried the Apple Cider Vinegar to wean off Prilosec? Does it work? I've drank it twice, and it's nasty!
PREVIOUS medications and discontinuations: Zoloft, 1997-1999; switch to Paxil, 1999-2002 ___2009 - 2015: Gabapentin, 900mg, 2010-2015: tapered of 9 weeks, last dose Sept. 2015, no symptoms ___ Lamictal, 300mg, 2009-2015, taper of 6 weeks, last dose Oct 2015,no symptoms ___ Valium, 40mg, 2008-2015, 8 week taper, last dose Dec 2015, no symptoms ___ 2016: Carafate 1mg (anti-ulcer med) 4x a day as needed. Prescribed but not taking it. ___ Prilosec 40mg; 28-Aug started 25% taper; 1-Oct 20mg a.m. + 15mg p.m. Stopped Nov 26, 2016 w/rebound acid but not too bad.---CURRENT MEDICATIONS---Supplements: 150 mg Mag chloride, 350mg Krill Oil, Milk Thistle, ProbioticFor nausea as needed: Zantac, 300mg only "as needed". Zofran 4mg for nausea; only take it when nausea is unbearable or phenegran.Xanax, 3 mg in 4 split doses, 2008-present Lexpro: 2002 - March 2016: 20 mg; Mar-Apr 2016: 8 week taper 20 mg - 10 mg; 8-June 9mg; 13-June 10 mg; 11-Sep 7.5 mg; 25-Sep 5 mg; 5-Oct 10mg; started taking Liquid Lexapro in Nov 2016; started taper with liquid 1-Jan-17 9mg; 22-Jan 8.1mg; 22-Feb 7.3 mg, (horrible nausea); 30-Mar, updosed to 7.6 (1st morning, not as much nausea, hopefully it will get better); nausea was brutal; 6-April, updosed to 7.9mg, hoping nausea will let up; nausea stopped on 14-April for 2 days so far; 17-April nausea started back up :( stopped supplements on 10-April

Levothyroxine
50mcg 18-April for hypothydroidism Stopped by dr. on 20-April too many side effects, going to try again in 6 months

#57 Frogie

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Posted 15 October 2016 - 06:44 AM

Hi Lili,
One more time, I realigned how similar our med history on both PPI and AD, including timing!
Ironically, after taking 16 yrs proacid 15 mg, my doctor suggest me to switch to antacid. I did about 3 weeks ago and that was when I started seeing lights with my WD symptoms. It made me wondering if PPI is somehow part of the reason of the Wd.
I just read this topic today. Hope sudden stop of the PPI won't cause me any future problem. I'm good so far with the prescribed antacid.


When you stopped your PPI were you nauseous? If so, how long?
Thanks...

Not nausea, but my typical WD symptoms, super dizzy, head pressure on the same day I stopped antacid. I was freaking out so updose lexapro from 2.7 to 3.7, feeling great for 1 week then all the symptoms back again, so updose again to 4.5 lex. All the hell broke since then experiencing severe drug reaction and WD. Been tapering since then getting worse each day.

How did you stop your Ppi?
PREVIOUS medications and discontinuations: Zoloft, 1997-1999; switch to Paxil, 1999-2002 ___2009 - 2015: Gabapentin, 900mg, 2010-2015: tapered of 9 weeks, last dose Sept. 2015, no symptoms ___ Lamictal, 300mg, 2009-2015, taper of 6 weeks, last dose Oct 2015,no symptoms ___ Valium, 40mg, 2008-2015, 8 week taper, last dose Dec 2015, no symptoms ___ 2016: Carafate 1mg (anti-ulcer med) 4x a day as needed. Prescribed but not taking it. ___ Prilosec 40mg; 28-Aug started 25% taper; 1-Oct 20mg a.m. + 15mg p.m. Stopped Nov 26, 2016 w/rebound acid but not too bad.---CURRENT MEDICATIONS---Supplements: 150 mg Mag chloride, 350mg Krill Oil, Milk Thistle, ProbioticFor nausea as needed: Zantac, 300mg only "as needed". Zofran 4mg for nausea; only take it when nausea is unbearable or phenegran.Xanax, 3 mg in 4 split doses, 2008-present Lexpro: 2002 - March 2016: 20 mg; Mar-Apr 2016: 8 week taper 20 mg - 10 mg; 8-June 9mg; 13-June 10 mg; 11-Sep 7.5 mg; 25-Sep 5 mg; 5-Oct 10mg; started taking Liquid Lexapro in Nov 2016; started taper with liquid 1-Jan-17 9mg; 22-Jan 8.1mg; 22-Feb 7.3 mg, (horrible nausea); 30-Mar, updosed to 7.6 (1st morning, not as much nausea, hopefully it will get better); nausea was brutal; 6-April, updosed to 7.9mg, hoping nausea will let up; nausea stopped on 14-April for 2 days so far; 17-April nausea started back up :( stopped supplements on 10-April

Levothyroxine
50mcg 18-April for hypothydroidism Stopped by dr. on 20-April too many side effects, going to try again in 6 months

#58 LexAnger

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Posted 15 October 2016 - 09:16 AM

Cold turkey
<p>2009 Mar.: lexapro 10mg for headache for 2 weeks.2009-2012: on and off 1/4 to 1/3 of 10mg2012 June--2013 Jan,: 1/4-1/3 of 10mg generic, bad jaw pain2013 Jan-Mar: 10 mg generic. severe jaw and head pain; Mar--Aug. started tapering (liquid ever since) from 10 to 5 (one step) then gradually down to 2.25 mg, first ever panic attack, severe head/jaw pain2013 Aug.: back to 2.75 mg; Nov: back to Brand Lex. 2.75mg -- 3mg, slight improvement with pain2014 June: stopped PPI, head pressure/numbness. up-dosed 4.5mg, severe reaction mental symptoms added on2014 Aug--2015 Aug: Micro taper down to 3.2mg, .025mg (<1%) cut holding 2-3 weeks.2015 Aug 15th, Accidental one dose of 4.2mg. worsening brain non-functional, swollen head, body, coma like, DR2016 Feb., started fast taper for the drug toxicity caused by the one dose of 4.2mg, dosing 10am through 11 pm everyday2/13--3.2mg, 3/15-- 2.9mg, 4/19-- 2.6mg, 6/26--2.2mg, 7/22 --1.9mg, 8/16--1.8mg,8/31--1.7m g, 9/13--1.6mg, 9/27--1.5mg, 10/8--1.4mg, 10/14--1.3mg, 11/1--1.2mg, 11/29--1.1mg, 12/12--1mg, 12/22--0.9mg2017: 1/7--0.8mg, 1/15--0.7mg, 1/17--0.6mg, 1/20--0.52, 1/21--0.4mg, 1/22--0.26, 1/23--0.2, sliding Down to 0.13mg by 2/13, then 0.07mg since 2/18, 0.06mg 2/20-3/17, 0.13mg 3/18

#59 Frogie

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Posted 15 October 2016 - 09:26 AM

Cold turkey


How did you handle the rebound acid?
PREVIOUS medications and discontinuations: Zoloft, 1997-1999; switch to Paxil, 1999-2002 ___2009 - 2015: Gabapentin, 900mg, 2010-2015: tapered of 9 weeks, last dose Sept. 2015, no symptoms ___ Lamictal, 300mg, 2009-2015, taper of 6 weeks, last dose Oct 2015,no symptoms ___ Valium, 40mg, 2008-2015, 8 week taper, last dose Dec 2015, no symptoms ___ 2016: Carafate 1mg (anti-ulcer med) 4x a day as needed. Prescribed but not taking it. ___ Prilosec 40mg; 28-Aug started 25% taper; 1-Oct 20mg a.m. + 15mg p.m. Stopped Nov 26, 2016 w/rebound acid but not too bad.---CURRENT MEDICATIONS---Supplements: 150 mg Mag chloride, 350mg Krill Oil, Milk Thistle, ProbioticFor nausea as needed: Zantac, 300mg only "as needed". Zofran 4mg for nausea; only take it when nausea is unbearable or phenegran.Xanax, 3 mg in 4 split doses, 2008-present Lexpro: 2002 - March 2016: 20 mg; Mar-Apr 2016: 8 week taper 20 mg - 10 mg; 8-June 9mg; 13-June 10 mg; 11-Sep 7.5 mg; 25-Sep 5 mg; 5-Oct 10mg; started taking Liquid Lexapro in Nov 2016; started taper with liquid 1-Jan-17 9mg; 22-Jan 8.1mg; 22-Feb 7.3 mg, (horrible nausea); 30-Mar, updosed to 7.6 (1st morning, not as much nausea, hopefully it will get better); nausea was brutal; 6-April, updosed to 7.9mg, hoping nausea will let up; nausea stopped on 14-April for 2 days so far; 17-April nausea started back up :( stopped supplements on 10-April

Levothyroxine
50mcg 18-April for hypothydroidism Stopped by dr. on 20-April too many side effects, going to try again in 6 months

#60 SMatthews

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Posted 18 November 2016 - 11:53 AM

I was not aware that acid blockers can have adverse neurological effects. I've had issues with GERD and esophageal spasms since I was a child. The spasms are triggered by reflux according to my gastroenterologist. I've taken acid blockers ever since I can remember and have been off and on PPIs for years. I've had depression issues ever since I can remember too. I'm now wondering if the acid blockers were/are a contributing factor.
 
I've previously read about the side effects of taking PPIs and weaned off them against my doctor's advice. I followed the steps in the article "How to Wean Off PPIs and Why" (http://howtotreathea...ff-ppis-and-why). My acid rebounding was rough. I still have heartburn and esophageal spams but they not as frequent. I've changed my eating habits and plan on trying lacto-fermented foods to see if they help balance the bacteria in my digestive system and eliminate my reflux. Has anyone tried lacto-fermented foods to eliminate GERD? Thanks!



#61 scallywag

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Posted 18 November 2016 - 06:05 PM

You can use a web search tool, such as Google, to search this site. Include site:survivingantidepressants.org as a search term with the topic of interest, "lacto-fermented food" in this instance.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.
1997-1999 Effexor; 2002-2005 Effexor XR 37.5 mg linear taper, dropping same #beads/week with bad results
Cymbalta (brand name), 60 mg 2012 - 2015; 20 mg to 7 mg in 2016, exact doses and dates in this post;
2017: 6.3 (58 beads) Feb. 1; 5.6 mg (52) Feb. 22; 5.4 mg (50) Mar. 15; 5.1 mg (47) Mar. 25; 4.9 mg (45) Apr. 5; 4.5 mg (42) Apr. 14; 3.5 mg (32) Apr. 26;
Current dose: 2.6 mg (24) 2017-May-17
+ Supplements: fish oil (1500 mg EPA/500 mg DHA), Vitamins: D3, K2, C; Minerals: Mg, Se, Cr, I, V
scallywag's Introduction
Online spreadsheet for dose taper calculations and nz11's THE WORKS spreadsheet


#62 btdt

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Posted 18 November 2016 - 07:36 PM

I was not aware that acid blockers can have adverse neurological effects. I've had issues with GERD and esophageal spasms since I was a child. The spasms are triggered by reflux according to my gastroenterologist. I've taken acid blockers ever since I can remember and have been off and on PPIs for years. I've had depression issues ever since I can remember too. I'm now wondering if the acid blockers were/are a contributing factor.
 
I've previously read about the side effects of taking PPIs and weaned off them against my doctor's advice. I followed the steps in the article "How to Wean Off PPIs and Why" (http://howtotreathea...ff-ppis-and-why). My acid rebounding was rough. I still have heartburn and esophageal spams but they not as frequent. I've changed my eating habits and plan on trying lacto-fermented foods to see if they help balance the bacteria in my digestive system and eliminate my reflux. Has anyone tried lacto-fermented foods to eliminate GERD? Thanks!

 

How PPI drugs affect depression and other drugs that are metabolized by P450 have both been covered in this thread on the previous posts. Please read back. 

 

Personally I had to cut pills and taper slowly and added other things like tums for break through acid baking soda and water Apple Cider vinegar and water both are helpful diet stress reduction thru meditation relaxation videos every bit helps... and sit up to sleep or raise your bed head for a time. 

 

I have used a lot of probiotics and colostrum new roots brand is what I use it really helped.... latest for me is candaclear four kills yeast and adds a probiotic... seems to be very helpful.  

 

Other things that helped when I was at my worst... apple sauce with three capsules of acidophilus mixed in the apple sauce is a prebiotic will give a growing medium (pectin) got this from a doc long ago... her other idea was florastor one pill and I had a big yeast problem ... could be I had it before but the florestore was not suppose to be a problem but it was... I have a full bottle still it is not cheap... none of this stuff is cheap.

 

 Really bad pain is helped by a cold pack sit upright chew slowly... sleep sitting up. No coffee... licorice did not help me but candied ginger did. I guess if a person lives long enough with these problems they will sort out what works for them. Chlorophyll helped me too...tho it is not pretty you will see if you try it...

 

Exercise helped me too... stretching neck rib shoulders back all help.

peace all 


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#63 anonymous4317

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Posted 19 March 2017 - 09:30 PM

I was prescribed Omeprazole 40 mg delayed-release capsules for 10 days for gastritis that showed up on an upper gastrointestinal endoscopy.

 

I have been taking it 7 days and need to get off. How long would you all recommend for tapering off? The OP says 25% each week, but would that be necessary seeing that I would be taking Omeprazole three more weeks?

 

Thanks!! The aspect of rebound acid scares me.


two years drug free as of May 2016, was on psychiatric drugs for four years (including three years on Pristiq)


#64 Altostrata

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Posted 19 March 2017 - 09:34 PM

Hello, anon. Just to be safe, I'd cut the dosage in half for 4 days, in half again for another 4 days, then go off.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

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#65 SMatthews

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Posted 20 March 2017 - 05:19 AM

Hello anonymous4317. It's not likely that your rebound would be as pronounced as those who have been on Omeprazole for longer time periods. You may be able to stop without tapering off and rely on an H2 blocker for any rebound in acid. In the past, I've taken numerous rounds of PPIs for 14 days and been ok with the use of an H2 blocker and antacids.



#66 mammaP

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Posted 21 March 2017 - 08:25 AM

Tapering will hopefully mean that no other drug will be needed. Taking care of the gut is better than relying on drugs, a good pro-biotic helps keep the good bacteria balanced and helps eliminate acid reflux. 


**I am not a medical professional, if in doubt please consult a doctor with withdrawal knowledge.

 

See how to create a signature here http://survivingantidepressants.org/index.php?/topic/12364-please-put-your-withdrawal-history-in-your-signature/

 

Many drugs for many years, prescribed diazepam first 1973, took occasionally. 3 or 4 tricyclics  for short periods.

1993 had a breakdown leading to 10 years of drug experiments with all classes of psych drugs.

2002  effexor. 

Tapered by counting beads from March 2012 to March 2013, ending with 5 beads.

Withdrawal April 2013 . Reinstated 5 beads reduced to 4 beads May 2013

Restarted taper  Nov 2013  

OFF EFFEXOR Feb 2015    :D 

 

Also tapered atenolol and omeprazole Dec 2013 - May 2014

 

Tapering tramadol, Feb 2015 100mg , March 2015 50mg -hold- Feb2016 46mg  March 8 2016 45 April 44mg  May 11  43mg June 14 42mg

Taking fish oil, magnesium, pro biotic.

 

My story http://survivinganti...king-in/page-33

 

Lesson learned, slow down taper at lower doses. Taper no more than 10% of CURRENT dose if possible

 

Following every sunset is a brand new day


#67 Marsha

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Posted 22 March 2017 - 07:42 AM

Yes very important to take care of the gut.
I try to take each day at a time, but some days hit me all at once. Will update my signature when I am ready.