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Be careful with l-tyrosine


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#1 Altostrata

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Posted 04 July 2014 - 10:38 AM

Tyrosine can be very activating, see http://www.livestron...e-side-effects/
 

Anxiety
Unusual anxiety may happen as a side effect of this amino acid, the Nutritional Supplements Help Guide reports. While this amino acid influences cognitive abilities, it still acts as a stimulant to your central nervous system. The ingestion of L-tyrosine can increase impulses in your nerve center of your body. Increased feelings of fear and panic may occur with use of this product on a regular basis.
 

 
Personally, I recently developed a sensitivity to tyrosine and its child tyramine, found in fermented foods, preserved foods, and other foods. If I eat substantial amounts of tyramine, it will keep me awake with a pounding heart.

 

Tyrosine and tyramine-containing foods also trigger migraines in some people.

 

You don't want to do this to yourself. Watch out for l-tyrosine.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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#2 Chemistry

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Posted 04 July 2014 - 02:39 PM

How did you figure out your sensitivity was Tyrosine and not something else? were you taking a supplement or were you eating certain foods and it triggered symptoms? Thanks for the heads up Alto.


2010 - citalopram 10mg 
2011 - 20-40mg, 1 month taper, PSSD & Anhedonia - Elavil 10mg during taper.
Clonazepam when needed after a month of daily use. 
2012 - Off Elavil - Zoloft (sertraline) 25mg - 50 mgs for 6 months + Buspar for a while. Pssd & anhedonia improved on zoloft, now has gotten a lot worse since a year off. 

 

Off all drugs since October 2012.


#3 Altostrata

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Posted 04 July 2014 - 04:18 PM

Certain foods high in tyramine.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

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#4 rapunzel2

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Posted 05 July 2014 - 12:10 AM

have you had your thyroid checked (including antibodies)? it may happen with people who have Hashimoto's. tyrosine effects thyroid hormons and people with Hashimoto feel hypothyroid as well as hyperthyroid symtoms. too much activation with tyrosine can be a hyperthyroid symptom. 


in 2002- cipramil for half a year, ended it uneventfully. in 2006 - citalopram for half a year, ended in horrific state, ditched the drugs CT. 2006-2008 not feeling well but drug free. in 2008 prozac 20mg + quetiapine 25mg. 2009 tried to stop, ended up in hole after couple of months, started zoloft. 2009-2011 zoloft 50mg. went to 25mg in 2011 summer, it resulted in half a year horrible suffering. reinstated, changed drugs, nothing happened. by 2012 beginning suddenly felt great and CT meds. after 4 months came suddenly most horrible human suffering that's possible. started tapering slowly, GFCF diet and Hardy Nutritionals vitamins in 2013 summer. 

current medications: 1) fluoxetine and quetiapine since Aug 2012; 2) Daily Essential Nutrients by Hardy Nutritionals 10 capsules / since May 2013 + omega3; 3) Gluten-free-casein-free diet since june 2013; 4) free form amino acid complex 3 capsules 5) milk thistle 6) niacin 1500mg

25. april'13 fluoxetine 40mg -> 36mg (10%); 25. may'13 fluoxetine 36mg -> 32mg (1 month inbetween, 11%); 4. july'13 fluoxetine 32mg-> 28mg (5,5 weeks, 13%); 27. july'13 quetiapine 50 -> 45mg (10%); 15. aug'13 fluoxetine 28mg -> 24mg (6 weeks, 14%); 29. sept'13 quetiapine 45 -> 40mg (1,5 months, 11%); 14. oct'13 quetiapine 40mg -> 35mg (2 weeks, 13%); 16. oct'13 quetiapine 35mg -> 40mg; 17. oct'13 fluoxetine 24mg -> 22 mg (8%); 4. feb’14 fluoxetine 22mg -> 21mg (3,5 months hold inbetween, 5% cut); 21. feb'14 fluoxetine 21mg -> 20,5mg (2,5 weeks, 2,4% cut); 27 feb'14 fluoxetine 20,5mg -> 20mg (1 week, 2,4% cut); 30 mar'14 fluoxetine 20mg -> 19,5mg (4,5 weeks, 2,4% cut); 17 may'14 quetiapine 40mg -> 31mg (22% cut); 31 may'14 fluoxetine 19,5mg -> 17,56mg (9,9%); 13 july'14 quetiapine 31mg -> 25mg (19% cut); 19 july'14 quetiapine 25mg -> 18, 75mg (25% cut, 6 days); 28. july'14 quetiapine 18,75mg -> 22mg (-15%); 9. aug'14 fluoxetine 17,52mg -> 17,12mg (2,3% cut, 10 weeks, over 2 months); 19. aug'14 back to 17,52mg due to bad withdrawal symptoms; 20. oct'14 fluoxetine 17,52 -> 17,2mg (1,8% cut); 28. nov'14 fluoxetine 17,2 -> 15,6 (9,8%); 9. feb’15 fluoxetine 15,6 -> 14,4 (7,7%); 3. may’15 quetiapine 22mg -> 19mg (-14%); 27. may’15 fluoxetine 14,4mg -> 12,6mg (-12,5%, 1,8mg); 2. july’15 fluoxetine 12,6mg -> 10,6mg (15,9%, 2mg); 26. oct'15 fluoxetine 10,6mg - 9mg (15%, 1,6mg); 18. jan'16 quetiapine 18mg -> 15mg (17%); 16. mar'16 fluoxetine 9mg -> 7,4mg (18%); 22.may'16 fluoxetine 7,4mg -> 6mg (19%); 19.sept'16 quetiapine 12,5 -> 11,25 (10%); 26. sept'16 quetiapine 11,25 -> 10,25 (9%), 3 oct'16 quetiapine 10,25 -> 9,25 (10%); 10 oc'16 quetiapine 9,25-> 8,25mg (11%), 14 nov'16 quetiapine 8,25 -> 7,25 (12%); 9 Jan'17 fluoxetine 6mg -> 5,8mg (3%): 18 jan fluoxetine 5,8mg -> 5,6mg (3%); 6 feb fluoxetine 5,6mg -> 5,4mg (4%); 19 feb fluoxetine 5,4mg -> 5,2mg (4%); 5 mar fluox 5,2 -> 5,0 (4%). 

 


#5 Altostrata

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Posted 05 July 2014 - 12:58 PM

rapunzel, what are your sources for that information?
This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

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#6 rapunzel2

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Posted 06 July 2014 - 01:59 AM

gee, I don't remember exactly. I think it was the book "Mood cure", which discusses amino acids. 


in 2002- cipramil for half a year, ended it uneventfully. in 2006 - citalopram for half a year, ended in horrific state, ditched the drugs CT. 2006-2008 not feeling well but drug free. in 2008 prozac 20mg + quetiapine 25mg. 2009 tried to stop, ended up in hole after couple of months, started zoloft. 2009-2011 zoloft 50mg. went to 25mg in 2011 summer, it resulted in half a year horrible suffering. reinstated, changed drugs, nothing happened. by 2012 beginning suddenly felt great and CT meds. after 4 months came suddenly most horrible human suffering that's possible. started tapering slowly, GFCF diet and Hardy Nutritionals vitamins in 2013 summer. 

current medications: 1) fluoxetine and quetiapine since Aug 2012; 2) Daily Essential Nutrients by Hardy Nutritionals 10 capsules / since May 2013 + omega3; 3) Gluten-free-casein-free diet since june 2013; 4) free form amino acid complex 3 capsules 5) milk thistle 6) niacin 1500mg

25. april'13 fluoxetine 40mg -> 36mg (10%); 25. may'13 fluoxetine 36mg -> 32mg (1 month inbetween, 11%); 4. july'13 fluoxetine 32mg-> 28mg (5,5 weeks, 13%); 27. july'13 quetiapine 50 -> 45mg (10%); 15. aug'13 fluoxetine 28mg -> 24mg (6 weeks, 14%); 29. sept'13 quetiapine 45 -> 40mg (1,5 months, 11%); 14. oct'13 quetiapine 40mg -> 35mg (2 weeks, 13%); 16. oct'13 quetiapine 35mg -> 40mg; 17. oct'13 fluoxetine 24mg -> 22 mg (8%); 4. feb’14 fluoxetine 22mg -> 21mg (3,5 months hold inbetween, 5% cut); 21. feb'14 fluoxetine 21mg -> 20,5mg (2,5 weeks, 2,4% cut); 27 feb'14 fluoxetine 20,5mg -> 20mg (1 week, 2,4% cut); 30 mar'14 fluoxetine 20mg -> 19,5mg (4,5 weeks, 2,4% cut); 17 may'14 quetiapine 40mg -> 31mg (22% cut); 31 may'14 fluoxetine 19,5mg -> 17,56mg (9,9%); 13 july'14 quetiapine 31mg -> 25mg (19% cut); 19 july'14 quetiapine 25mg -> 18, 75mg (25% cut, 6 days); 28. july'14 quetiapine 18,75mg -> 22mg (-15%); 9. aug'14 fluoxetine 17,52mg -> 17,12mg (2,3% cut, 10 weeks, over 2 months); 19. aug'14 back to 17,52mg due to bad withdrawal symptoms; 20. oct'14 fluoxetine 17,52 -> 17,2mg (1,8% cut); 28. nov'14 fluoxetine 17,2 -> 15,6 (9,8%); 9. feb’15 fluoxetine 15,6 -> 14,4 (7,7%); 3. may’15 quetiapine 22mg -> 19mg (-14%); 27. may’15 fluoxetine 14,4mg -> 12,6mg (-12,5%, 1,8mg); 2. july’15 fluoxetine 12,6mg -> 10,6mg (15,9%, 2mg); 26. oct'15 fluoxetine 10,6mg - 9mg (15%, 1,6mg); 18. jan'16 quetiapine 18mg -> 15mg (17%); 16. mar'16 fluoxetine 9mg -> 7,4mg (18%); 22.may'16 fluoxetine 7,4mg -> 6mg (19%); 19.sept'16 quetiapine 12,5 -> 11,25 (10%); 26. sept'16 quetiapine 11,25 -> 10,25 (9%), 3 oct'16 quetiapine 10,25 -> 9,25 (10%); 10 oc'16 quetiapine 9,25-> 8,25mg (11%), 14 nov'16 quetiapine 8,25 -> 7,25 (12%); 9 Jan'17 fluoxetine 6mg -> 5,8mg (3%): 18 jan fluoxetine 5,8mg -> 5,6mg (3%); 6 feb fluoxetine 5,6mg -> 5,4mg (4%); 19 feb fluoxetine 5,4mg -> 5,2mg (4%); 5 mar fluox 5,2 -> 5,0 (4%). 

 


#7 rapunzel2

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Posted 06 July 2014 - 04:01 AM

also I listened to the thyroid summit http://thethyroidsummit.com/


in 2002- cipramil for half a year, ended it uneventfully. in 2006 - citalopram for half a year, ended in horrific state, ditched the drugs CT. 2006-2008 not feeling well but drug free. in 2008 prozac 20mg + quetiapine 25mg. 2009 tried to stop, ended up in hole after couple of months, started zoloft. 2009-2011 zoloft 50mg. went to 25mg in 2011 summer, it resulted in half a year horrible suffering. reinstated, changed drugs, nothing happened. by 2012 beginning suddenly felt great and CT meds. after 4 months came suddenly most horrible human suffering that's possible. started tapering slowly, GFCF diet and Hardy Nutritionals vitamins in 2013 summer. 

current medications: 1) fluoxetine and quetiapine since Aug 2012; 2) Daily Essential Nutrients by Hardy Nutritionals 10 capsules / since May 2013 + omega3; 3) Gluten-free-casein-free diet since june 2013; 4) free form amino acid complex 3 capsules 5) milk thistle 6) niacin 1500mg

25. april'13 fluoxetine 40mg -> 36mg (10%); 25. may'13 fluoxetine 36mg -> 32mg (1 month inbetween, 11%); 4. july'13 fluoxetine 32mg-> 28mg (5,5 weeks, 13%); 27. july'13 quetiapine 50 -> 45mg (10%); 15. aug'13 fluoxetine 28mg -> 24mg (6 weeks, 14%); 29. sept'13 quetiapine 45 -> 40mg (1,5 months, 11%); 14. oct'13 quetiapine 40mg -> 35mg (2 weeks, 13%); 16. oct'13 quetiapine 35mg -> 40mg; 17. oct'13 fluoxetine 24mg -> 22 mg (8%); 4. feb’14 fluoxetine 22mg -> 21mg (3,5 months hold inbetween, 5% cut); 21. feb'14 fluoxetine 21mg -> 20,5mg (2,5 weeks, 2,4% cut); 27 feb'14 fluoxetine 20,5mg -> 20mg (1 week, 2,4% cut); 30 mar'14 fluoxetine 20mg -> 19,5mg (4,5 weeks, 2,4% cut); 17 may'14 quetiapine 40mg -> 31mg (22% cut); 31 may'14 fluoxetine 19,5mg -> 17,56mg (9,9%); 13 july'14 quetiapine 31mg -> 25mg (19% cut); 19 july'14 quetiapine 25mg -> 18, 75mg (25% cut, 6 days); 28. july'14 quetiapine 18,75mg -> 22mg (-15%); 9. aug'14 fluoxetine 17,52mg -> 17,12mg (2,3% cut, 10 weeks, over 2 months); 19. aug'14 back to 17,52mg due to bad withdrawal symptoms; 20. oct'14 fluoxetine 17,52 -> 17,2mg (1,8% cut); 28. nov'14 fluoxetine 17,2 -> 15,6 (9,8%); 9. feb’15 fluoxetine 15,6 -> 14,4 (7,7%); 3. may’15 quetiapine 22mg -> 19mg (-14%); 27. may’15 fluoxetine 14,4mg -> 12,6mg (-12,5%, 1,8mg); 2. july’15 fluoxetine 12,6mg -> 10,6mg (15,9%, 2mg); 26. oct'15 fluoxetine 10,6mg - 9mg (15%, 1,6mg); 18. jan'16 quetiapine 18mg -> 15mg (17%); 16. mar'16 fluoxetine 9mg -> 7,4mg (18%); 22.may'16 fluoxetine 7,4mg -> 6mg (19%); 19.sept'16 quetiapine 12,5 -> 11,25 (10%); 26. sept'16 quetiapine 11,25 -> 10,25 (9%), 3 oct'16 quetiapine 10,25 -> 9,25 (10%); 10 oc'16 quetiapine 9,25-> 8,25mg (11%), 14 nov'16 quetiapine 8,25 -> 7,25 (12%); 9 Jan'17 fluoxetine 6mg -> 5,8mg (3%): 18 jan fluoxetine 5,8mg -> 5,6mg (3%); 6 feb fluoxetine 5,6mg -> 5,4mg (4%); 19 feb fluoxetine 5,4mg -> 5,2mg (4%); 5 mar fluox 5,2 -> 5,0 (4%). 

 


#8 Altostrata

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Posted 06 July 2014 - 02:01 PM

Please always supply references so people can verify the information you provide.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

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#9 rapunzel2

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Posted 07 July 2014 - 04:47 AM

ok! the book is here: http://www.amazon.co...words=mood cure

 

and the summit link I gave, but it costs now.

 

I started with tyrosine today, took 1000mg, and I feel ok. 


in 2002- cipramil for half a year, ended it uneventfully. in 2006 - citalopram for half a year, ended in horrific state, ditched the drugs CT. 2006-2008 not feeling well but drug free. in 2008 prozac 20mg + quetiapine 25mg. 2009 tried to stop, ended up in hole after couple of months, started zoloft. 2009-2011 zoloft 50mg. went to 25mg in 2011 summer, it resulted in half a year horrible suffering. reinstated, changed drugs, nothing happened. by 2012 beginning suddenly felt great and CT meds. after 4 months came suddenly most horrible human suffering that's possible. started tapering slowly, GFCF diet and Hardy Nutritionals vitamins in 2013 summer. 

current medications: 1) fluoxetine and quetiapine since Aug 2012; 2) Daily Essential Nutrients by Hardy Nutritionals 10 capsules / since May 2013 + omega3; 3) Gluten-free-casein-free diet since june 2013; 4) free form amino acid complex 3 capsules 5) milk thistle 6) niacin 1500mg

25. april'13 fluoxetine 40mg -> 36mg (10%); 25. may'13 fluoxetine 36mg -> 32mg (1 month inbetween, 11%); 4. july'13 fluoxetine 32mg-> 28mg (5,5 weeks, 13%); 27. july'13 quetiapine 50 -> 45mg (10%); 15. aug'13 fluoxetine 28mg -> 24mg (6 weeks, 14%); 29. sept'13 quetiapine 45 -> 40mg (1,5 months, 11%); 14. oct'13 quetiapine 40mg -> 35mg (2 weeks, 13%); 16. oct'13 quetiapine 35mg -> 40mg; 17. oct'13 fluoxetine 24mg -> 22 mg (8%); 4. feb’14 fluoxetine 22mg -> 21mg (3,5 months hold inbetween, 5% cut); 21. feb'14 fluoxetine 21mg -> 20,5mg (2,5 weeks, 2,4% cut); 27 feb'14 fluoxetine 20,5mg -> 20mg (1 week, 2,4% cut); 30 mar'14 fluoxetine 20mg -> 19,5mg (4,5 weeks, 2,4% cut); 17 may'14 quetiapine 40mg -> 31mg (22% cut); 31 may'14 fluoxetine 19,5mg -> 17,56mg (9,9%); 13 july'14 quetiapine 31mg -> 25mg (19% cut); 19 july'14 quetiapine 25mg -> 18, 75mg (25% cut, 6 days); 28. july'14 quetiapine 18,75mg -> 22mg (-15%); 9. aug'14 fluoxetine 17,52mg -> 17,12mg (2,3% cut, 10 weeks, over 2 months); 19. aug'14 back to 17,52mg due to bad withdrawal symptoms; 20. oct'14 fluoxetine 17,52 -> 17,2mg (1,8% cut); 28. nov'14 fluoxetine 17,2 -> 15,6 (9,8%); 9. feb’15 fluoxetine 15,6 -> 14,4 (7,7%); 3. may’15 quetiapine 22mg -> 19mg (-14%); 27. may’15 fluoxetine 14,4mg -> 12,6mg (-12,5%, 1,8mg); 2. july’15 fluoxetine 12,6mg -> 10,6mg (15,9%, 2mg); 26. oct'15 fluoxetine 10,6mg - 9mg (15%, 1,6mg); 18. jan'16 quetiapine 18mg -> 15mg (17%); 16. mar'16 fluoxetine 9mg -> 7,4mg (18%); 22.may'16 fluoxetine 7,4mg -> 6mg (19%); 19.sept'16 quetiapine 12,5 -> 11,25 (10%); 26. sept'16 quetiapine 11,25 -> 10,25 (9%), 3 oct'16 quetiapine 10,25 -> 9,25 (10%); 10 oc'16 quetiapine 9,25-> 8,25mg (11%), 14 nov'16 quetiapine 8,25 -> 7,25 (12%); 9 Jan'17 fluoxetine 6mg -> 5,8mg (3%): 18 jan fluoxetine 5,8mg -> 5,6mg (3%); 6 feb fluoxetine 5,6mg -> 5,4mg (4%); 19 feb fluoxetine 5,4mg -> 5,2mg (4%); 5 mar fluox 5,2 -> 5,0 (4%). 

 


#10 Altostrata

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Posted 07 July 2014 - 01:42 PM

What benefits do you expect from tyrosine, and why? Please give references.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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#11 rapunzel2

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Posted 07 July 2014 - 11:06 PM

relief from tiredness. it should stimulate thyroid and also dopamine production (although I know the neurotransmitter inbalance theory is wrong). source: "mood cure" book. 

 

I haven't felt any effects from it though. tryptophan seems to be far more effective for me. but of course, it's early to tell, too. 


in 2002- cipramil for half a year, ended it uneventfully. in 2006 - citalopram for half a year, ended in horrific state, ditched the drugs CT. 2006-2008 not feeling well but drug free. in 2008 prozac 20mg + quetiapine 25mg. 2009 tried to stop, ended up in hole after couple of months, started zoloft. 2009-2011 zoloft 50mg. went to 25mg in 2011 summer, it resulted in half a year horrible suffering. reinstated, changed drugs, nothing happened. by 2012 beginning suddenly felt great and CT meds. after 4 months came suddenly most horrible human suffering that's possible. started tapering slowly, GFCF diet and Hardy Nutritionals vitamins in 2013 summer. 

current medications: 1) fluoxetine and quetiapine since Aug 2012; 2) Daily Essential Nutrients by Hardy Nutritionals 10 capsules / since May 2013 + omega3; 3) Gluten-free-casein-free diet since june 2013; 4) free form amino acid complex 3 capsules 5) milk thistle 6) niacin 1500mg

25. april'13 fluoxetine 40mg -> 36mg (10%); 25. may'13 fluoxetine 36mg -> 32mg (1 month inbetween, 11%); 4. july'13 fluoxetine 32mg-> 28mg (5,5 weeks, 13%); 27. july'13 quetiapine 50 -> 45mg (10%); 15. aug'13 fluoxetine 28mg -> 24mg (6 weeks, 14%); 29. sept'13 quetiapine 45 -> 40mg (1,5 months, 11%); 14. oct'13 quetiapine 40mg -> 35mg (2 weeks, 13%); 16. oct'13 quetiapine 35mg -> 40mg; 17. oct'13 fluoxetine 24mg -> 22 mg (8%); 4. feb’14 fluoxetine 22mg -> 21mg (3,5 months hold inbetween, 5% cut); 21. feb'14 fluoxetine 21mg -> 20,5mg (2,5 weeks, 2,4% cut); 27 feb'14 fluoxetine 20,5mg -> 20mg (1 week, 2,4% cut); 30 mar'14 fluoxetine 20mg -> 19,5mg (4,5 weeks, 2,4% cut); 17 may'14 quetiapine 40mg -> 31mg (22% cut); 31 may'14 fluoxetine 19,5mg -> 17,56mg (9,9%); 13 july'14 quetiapine 31mg -> 25mg (19% cut); 19 july'14 quetiapine 25mg -> 18, 75mg (25% cut, 6 days); 28. july'14 quetiapine 18,75mg -> 22mg (-15%); 9. aug'14 fluoxetine 17,52mg -> 17,12mg (2,3% cut, 10 weeks, over 2 months); 19. aug'14 back to 17,52mg due to bad withdrawal symptoms; 20. oct'14 fluoxetine 17,52 -> 17,2mg (1,8% cut); 28. nov'14 fluoxetine 17,2 -> 15,6 (9,8%); 9. feb’15 fluoxetine 15,6 -> 14,4 (7,7%); 3. may’15 quetiapine 22mg -> 19mg (-14%); 27. may’15 fluoxetine 14,4mg -> 12,6mg (-12,5%, 1,8mg); 2. july’15 fluoxetine 12,6mg -> 10,6mg (15,9%, 2mg); 26. oct'15 fluoxetine 10,6mg - 9mg (15%, 1,6mg); 18. jan'16 quetiapine 18mg -> 15mg (17%); 16. mar'16 fluoxetine 9mg -> 7,4mg (18%); 22.may'16 fluoxetine 7,4mg -> 6mg (19%); 19.sept'16 quetiapine 12,5 -> 11,25 (10%); 26. sept'16 quetiapine 11,25 -> 10,25 (9%), 3 oct'16 quetiapine 10,25 -> 9,25 (10%); 10 oc'16 quetiapine 9,25-> 8,25mg (11%), 14 nov'16 quetiapine 8,25 -> 7,25 (12%); 9 Jan'17 fluoxetine 6mg -> 5,8mg (3%): 18 jan fluoxetine 5,8mg -> 5,6mg (3%); 6 feb fluoxetine 5,6mg -> 5,4mg (4%); 19 feb fluoxetine 5,4mg -> 5,2mg (4%); 5 mar fluox 5,2 -> 5,0 (4%). 

 


#12 Lilu

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Posted 10 July 2014 - 08:52 AM

What benefits do you expect from tyrosine, and why? Please give references.

 

L-Tyrosine is a precursor to norepinephrine, which increases energy, alertness, clarity of mind, motivation, etc.  I get that effect when I take high doses of Sudafed, which also increases norepinephrine.  Unfortunately, Sudafed or pseudoephedrine also causes insomnia.  And as I recently learned, it is anticholinergic, and relaxes smooth muscle tissue. Good for urinary incontinence or urgency. Bad for GERD or any kind of reflux problems.  I found this info on a clinical GI motility site.

 

This was my recent experience with L-Tyrosine. After a week of taking 750 mg, along with 100 mg of 5-HTP, I developed severe reflux, burping, and regurgitation accompanied with chest pain and a feeling that food was getting stuck in my lower esophagus.  I had also been on Allegra for a month at that point, which is also anticholinergic and can worsen reflux, heartburn, and GERD.  

 

I stopped both the Allegra and the L-Tyrosine, but continued to suffer with the same symptoms for over two months now.  Slowly my body has been going back to normal. But I still don't know what happened and if it was the L-Tyrosine or the Allegra.  I have ruled out 5-HTP since through research I found out that Serotonin is actually a natural pro-motility agent and promotes peristalsis.  (I can't find the link to the website right nowl)


2005-2008 Effexor xr; 1/2008 Tapered 3 months, then quit.
7/2008-2009 Reinstated Effexor xr due to crying spells.
2009-3/2013 Switched to Pristiq 50 mg then 100 mg
3/2013 Switched to Lexapro 10mg. Cut down to 5 mg. CT for 2 weeks then reinstated for 6 weeks
8/2013-8/2014 Tapering Lexapro
11/2014 -8/2015: Developed severe insomnia, resumed using Ambien & Klonopin
12/2014-6/2015 Tried Ativan, Lunesta, Sonata, Trazadone, Seroquel, Rameron - Adverse Reactions
7/2015 Reinstated Lexapro at 2 mg; Quit Klonopin CT suddenly paradoxical)
Started Gabapentin 100-300 mg for 3 weeks. Developed severe lumbar jerking movements (myoclonus).Quit Gabapentin CT.
8/2015 Continuing Lexapro 2 mg. Baclofen 10mg-AM/20mg-PM - tapered off by 5/2016
1-7/2016 Lexapro 5 mg 
Intro page: http://survivinganti...rsened-by-meds/


#13 Cdav

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Posted 08 July 2015 - 08:35 AM

Could L-tyrosine help akathisia? Due to its effect on dopamine? I want to try it, but I'm afraid of worsening my symptoms. 


-Effexor 150 mgs (2001-2009). Severe withdrawal symptoms during and after tapering for 6 months.  

-Pristiq 50 mg (2009-2012) Tapered over a year. Worst year of my life. 

-Prozac 20 mg (2012) Tapered over 6 moths to ease withdrawal. Still had severe WD symptoms. 

- (2012-2014) Doctor tried more than 20 medications for depression and WD, leaving me hypersensitive, and in protracted withdrawal. 

- Most debilitating symptoms during protracted withdrawal have been deep depression, anxiety, brain zaps, fatigue, akathisia, twitching, headaches and terrible PMS. 

-January 2015: Started Lamictal 12.5 mg, increased to 25 mg.- Bad reaction when updosed to 50 mg. Stopped. 

-February 2015: Doctor tried new antidepressant Brintellix - Horrible reaction. Discontinued completely. Severe AKATHISIA started.

-March 2015:  Started TMS therapy (Transcranial magnetic stimulation) for severe depression. Didn't work. 

-July 23-August 12: Had 10 ECT sessions which took away my protracted withdrawal symptoms including: akathisia, brain zaps, muscle twitches, fatigue and depression. Stopped medications. 

-September 2015: Experiencing bouts of depression again and muscle twitching. 

-March 2016: Started 20 mg Nortryptiline for depression. It helped. 

-August 2016: Slowly tapering Nortryptiline. 


#14 Altostrata

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Posted 08 September 2015 - 05:09 PM

The problem with l-tyrosine, as I found out recently, is that it can be metabolized in many different directions. How you metabolize it depends on a zillion factors, your genome among them.

 

It's one of those things that make some people feel better, and some worse.

 

A bad reaction to tyrosine has nothing to do with thyroid status, although for people who are hyperthyroid (Graves) it's probably not a good idea to even try it.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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#15 Newbeginning

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Posted 11 October 2015 - 09:04 PM

Has anyone tried L-tyrosine for apathy/low motivation? Or other supplements for dopamine? I searched it inthe forum and it gave me 0 results...


  • SSRIs 3-4 times in the last 14 years; would take them for 6-8 months and then taper off under dr supervision with no problems.
  • Med history prior to 2015: http://survivinganti...313#entry267313
  • 04/2015: Prozac decreased to 15mg over last 3 months; effexor held steady at 8mg; current effexor XR: 20 beads of a 75mg capsule per day (about 8mg)
  • 06/2015: Prozac: 10mg; effexor XR: 19 beads (about 7.5mg); 07/2015: Prozac: 8.5mg; effexor 18 beads; 08/2015: Prozac: 7.5mg; effexor: 17 beads
  • End of August: withdrawal: depressive symptoms, crying spells. Realized I was measuring prozac dose wrong for the last 2 months. Reinstated Prozac 8.5mg; Kept effexor at 17 beads. Stabilized in 5 weeks.
  • 10/2015: Prozac: 8.5mg; effexor: 17 beads
  • 11/2015: Prozac: 1.9ml (7.5mg); effexor: 16 beads
  • 12/2015: Prozac: 1.6ml; effexor xr: 16 beads. Withdrawal: neuroemotions
  • 01/2016: prozac: 1.6ml; effexor xr: reinstated 17 beads, withdrawal improved; 02/2016: Prozac 1.5ml; Effexor: 17 beads; 03/2016: Prozac 1.3ml(5mg); Effexor: 17 beads (7mg)-withdrawal (flu-like malaise, lightheaded, drowsy) started end of March. April 15: reinstated Prozac 1.5ml. Stabilized. 2 weeks ok. End of April: Withdrawal (neuroemotions). Eventually stabilized in April-May. Apathy improved.
  • 3 month hold until August. August 2016: apathy came back;

  • October 2016: updosed to Prozac 1.6ml. Bad reaction: anxiety, depression. End of October: went down Prozac 1.5ml. Stabilized over several weeks.

  • Dec 9: tried macca for energy: anxiety/depression. Improved over several weeks, but not completely resolved.

  • Dec 31: cut Effexor 5% to 16 beads. After 9 days: withdrawal anxiety, depression

     


#16 Newbeginning

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Posted 14 October 2015 - 05:34 PM

What Alto mentioned about tyramine reminded me of the reaction people taking MAOIs have when they eat things containing tyramine (like dangerously high blood pressure). It might mean either her system is sensitive to (or withdrawal has sensitized her to) the same processes in the brain that react to MAOIs.

 

I realize stimulants are not a good thing if your withdrawal issues are mostly related to over-arousal (like anxiety). Mine are mostly related to apathy so people who have this might react differently. In my experience so far, things that used to stimulate me before I experienced withdrawal no longer have a mood or energy stimulationg effect on me. They might keep me up at night, but other than that they don't stimulate much.

 

I will try the tyrosine but if I develop insomnia won't keep taking it. I have trouble swleeping at night to start with because I'm a night owl and don't need anything that will make that worse.

 

If any of you has tried it, could you share if the insomnia goes away? Or how it has helped you?

 

Reading about dopamine, it seems everything I'm experiencing sounds like a problem with that neurotransmitter. I realize neurotransmitters are all connected (like hormones) and it's more an issue of their balance rather than a "deficiency" of one. So just increasing dopamine production might not do much. Just not sure what else to do.


  • SSRIs 3-4 times in the last 14 years; would take them for 6-8 months and then taper off under dr supervision with no problems.
  • Med history prior to 2015: http://survivinganti...313#entry267313
  • 04/2015: Prozac decreased to 15mg over last 3 months; effexor held steady at 8mg; current effexor XR: 20 beads of a 75mg capsule per day (about 8mg)
  • 06/2015: Prozac: 10mg; effexor XR: 19 beads (about 7.5mg); 07/2015: Prozac: 8.5mg; effexor 18 beads; 08/2015: Prozac: 7.5mg; effexor: 17 beads
  • End of August: withdrawal: depressive symptoms, crying spells. Realized I was measuring prozac dose wrong for the last 2 months. Reinstated Prozac 8.5mg; Kept effexor at 17 beads. Stabilized in 5 weeks.
  • 10/2015: Prozac: 8.5mg; effexor: 17 beads
  • 11/2015: Prozac: 1.9ml (7.5mg); effexor: 16 beads
  • 12/2015: Prozac: 1.6ml; effexor xr: 16 beads. Withdrawal: neuroemotions
  • 01/2016: prozac: 1.6ml; effexor xr: reinstated 17 beads, withdrawal improved; 02/2016: Prozac 1.5ml; Effexor: 17 beads; 03/2016: Prozac 1.3ml(5mg); Effexor: 17 beads (7mg)-withdrawal (flu-like malaise, lightheaded, drowsy) started end of March. April 15: reinstated Prozac 1.5ml. Stabilized. 2 weeks ok. End of April: Withdrawal (neuroemotions). Eventually stabilized in April-May. Apathy improved.
  • 3 month hold until August. August 2016: apathy came back;

  • October 2016: updosed to Prozac 1.6ml. Bad reaction: anxiety, depression. End of October: went down Prozac 1.5ml. Stabilized over several weeks.

  • Dec 9: tried macca for energy: anxiety/depression. Improved over several weeks, but not completely resolved.

  • Dec 31: cut Effexor 5% to 16 beads. After 9 days: withdrawal anxiety, depression

     


#17 LostInSpace

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Posted 24 October 2015 - 07:23 PM

Has anyone tried L-tyrosine for apathy/low motivation? Or other supplements for dopamine? I searched it inthe forum and it gave me 0 results...

I tried tyrosine, It made me anxious and sweaty... I normally don't sweat much at all.  It also gave me a body odor I'd never smelled before.  Beware.  


1996-2014 - 3mg Clonazepam - Started weaning off in 2010, took 4 years.  All is fine.

2010-2014 - 30mg - 180mg percocets per day.  Quit CT in 2014.  All is fine.

2010-2014 - Mixed in Suboxen while not on percs... 8mg-32mg per day.  Quit CT in 2014.  All is fine (I think)  Opiates don't fully work yet.

2015 - Quit smoking weed, all is fine.

2015- Stopped drinking, all is fine.

2015-  Stopped drinking coffee, all is fine.

2010-2014 - 10mg of Lexapro for first 2 years, then 15mg for another 2 years

Quit over 3 week period - still experiencing bad withdrawal, but very slowly getting better... too slow.  

9/4/2015 - Reinstated 1mg liquid Lexapro.  So far, it's not helping... maybe hurting but not sure yet.

9/5/2015 - Stopped the 1mg, made it worse.  I will ride it out, currently drug free.

 

"The harder the battle, the sweeter the victory"


#18 Altostrata

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Posted 25 October 2015 - 04:10 PM

The problem with l-tyrosine, as I found out recently, is that it can be metabolized in many different directions. How you metabolize it depends on a zillion factors, your genome among them.

 

It's one of those things that make some people feel better, and some worse.

 

A bad reaction to tyrosine has nothing to do with thyroid status, although for people who are hyperthyroid (Graves) it's probably not a good idea to even try it.

 

One of the ways tyrosine can be metabolized is to tyramine. For some people, this will be very uncomfortable -- like the type of food reaction you might get if you were taking an MAOI.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#19 Newbeginning

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Posted 16 January 2016 - 08:54 PM

I might have had a bad reaction to l-tyrosine too. I'm having more anxiety, which I did not have before at all. Not sure it's caused by the l-tyrosine (could be other things) and this only began 2 months after starting l-tyrosine.

 

If it is due to l-tyrosine, anyone has an idea how long it will take for this side effect to go away now that I'm no longer on l-tyrosine?

 

thanks!


  • SSRIs 3-4 times in the last 14 years; would take them for 6-8 months and then taper off under dr supervision with no problems.
  • Med history prior to 2015: http://survivinganti...313#entry267313
  • 04/2015: Prozac decreased to 15mg over last 3 months; effexor held steady at 8mg; current effexor XR: 20 beads of a 75mg capsule per day (about 8mg)
  • 06/2015: Prozac: 10mg; effexor XR: 19 beads (about 7.5mg); 07/2015: Prozac: 8.5mg; effexor 18 beads; 08/2015: Prozac: 7.5mg; effexor: 17 beads
  • End of August: withdrawal: depressive symptoms, crying spells. Realized I was measuring prozac dose wrong for the last 2 months. Reinstated Prozac 8.5mg; Kept effexor at 17 beads. Stabilized in 5 weeks.
  • 10/2015: Prozac: 8.5mg; effexor: 17 beads
  • 11/2015: Prozac: 1.9ml (7.5mg); effexor: 16 beads
  • 12/2015: Prozac: 1.6ml; effexor xr: 16 beads. Withdrawal: neuroemotions
  • 01/2016: prozac: 1.6ml; effexor xr: reinstated 17 beads, withdrawal improved; 02/2016: Prozac 1.5ml; Effexor: 17 beads; 03/2016: Prozac 1.3ml(5mg); Effexor: 17 beads (7mg)-withdrawal (flu-like malaise, lightheaded, drowsy) started end of March. April 15: reinstated Prozac 1.5ml. Stabilized. 2 weeks ok. End of April: Withdrawal (neuroemotions). Eventually stabilized in April-May. Apathy improved.
  • 3 month hold until August. August 2016: apathy came back;

  • October 2016: updosed to Prozac 1.6ml. Bad reaction: anxiety, depression. End of October: went down Prozac 1.5ml. Stabilized over several weeks.

  • Dec 9: tried macca for energy: anxiety/depression. Improved over several weeks, but not completely resolved.

  • Dec 31: cut Effexor 5% to 16 beads. After 9 days: withdrawal anxiety, depression

     


#20 btdt

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Posted 25 August 2016 - 03:18 AM

To glean some ideas of what tyrosine problems and possible reactions to supplements I took up Tyrosinemia....yes it is all ball park not the direct base still I have learned helpful things this way. One thing always lead to another on the web and often I find the gems live there following leads. 

 

Tyrosinemia is genetic issue same thing I read about mitochondria when I first started seeking how to heal myself from this years ago...mitochondria too was thought to be a gentic disorder.  One day I found a science article stating porzac causes mitochondria disorders and I will not be surprised at all to find the same with tyrosine... I actually may have posted the proper evidence article but due to my own crappy brain power just now I can't think straight ... it took me ages today to remember the word mitochondria... something that came easily a short time ago... as easy as spelling my own name ...now again I struggle with it.  For me it comes and goes this round has been especially long. 

 

 

tyrosinemia

Tyrosinemia is a genetic disorder characterized by disruptions in the multistep process that breaks down the amino acid tyrosine, a building block of most proteins. If untreated, tyrosine and its byproducts build up in tissues and organs, which can lead to serious health problems.

There are three types of tyrosinemia, which are each distinguished by their symptoms and genetic cause. Tyrosinemia type I, the most severe form of this disorder, is characterized by signs and symptoms that begin in the first few months of life. Affected infants fail to gain weight and grow at the expected rate (failure to thrive) due to poor food tolerance because high-protein foods lead to diarrhea and vomiting. Affected infants may also have yellowing of the skin and whites of the eyes (jaundice), a cabbage-like odor, and an increased tendency to bleed (particularly nosebleeds). Tyrosinemia type I can lead to liver and kidney failure, softening and weakening of the bones (rickets), and an increased risk ofliver cancer (hepatocellular carcinoma). Some affected children have repeated neurologic crises that consist of changes in mental state, reduced sensation in the arms and legs (peripheral neuropathy), abdominal pain, and respiratory failure. These crises can last from 1 to 7 days. Untreated, children withtyrosinemia type I often do not survive past the age of 10.

Tyrosinemia type II can affect the eyes, skin, and mental development. Signs and symptoms often begin in early childhood and include eye pain and redness, excessive tearing, abnormal sensitivity to light (photophobia), and thick, painful skin on the palms of their hands and soles of their feet (palmoplantar hyperkeratosis). About 50 percent of individuals with tyrosinemia type II have some degree of intellectual disability.

Tyrosinemia type III is the rarest of the three types. The characteristic features of this type include intellectual disability, seizures, and periodic loss of balance and coordination (intermittent ataxia).

About 10 percent of newborns have temporarily elevated levels of tyrosine (transient tyrosinemia). In these cases, the cause is not genetic. The most likely causes are vitamin C deficiency or immature liver enzymes due to premature birth.

https://ghr.nlm.nih....ion/tyrosinemia

 

Check the last line liver enzymes same old common denominators keep popping up.  Many people who have taken ADs have a thyroid problem this is listed on all these drug as a side effect. 

 

I believe I have already posted a science article stating 

ADs alter the way our bodies use the above I just can't find it. 

peace


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#21 Terry4949

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Posted 09 November 2016 - 10:26 AM

has anyone had any experience with l tyrosine for depression , read some good stuff on it was wondering if it was worth trying a small dose , I can't seem to find anything in the symptoms and self care section on it ,
100mg Effexor 2000 untill jan 2015 severe withdrawals . Tapered 4weeks.
Jan to end of Feb 4 weeks on 15mg mirtazapine 20mg quetiapine , tapered of both 2 weeks , severe withdrawals , still some from Effexor possibly
End of Feb 2015 to end of July 30mg citolapram tapered 2weeks severe withdrawal , anxiety high , bouts of sever depression , severe emotional moods
Currently on 30mg mirtazapine appx 5 months , high anxiety, March cut dose 22.5 mg going on to liquid still no improvements with the depression , also started sept 2015 200mg pregabalin , currently on 22.5mg mirtazapine tablet form doing really badly. Cut beginning of May remeron 20mg still bad anxiety,August 15mg remeron ,100mg pregablin , severe depression headaches anxiety , oct 2016 doctor stoped pregablin c/t , 15mg mirtazapine still no let up in physical symptoms ,high anxiety ,Nov 2016 remeron 13.5 mg , Jan 2017 mirtazapine stopped flouxetine20mg added by hospital admission, no choice , doing really badly , akathesia suicidel ,, Flouxetine c/t by hospital after 7 weeks 20mg daily , currently on nothing , God help me

#22 spacecadet

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Posted 11 January 2017 - 09:14 PM

I, too, have read "the mood cure" when starting the tapering process. Has anyone else read it and what thoughts do you have? 


2009- 10 mg paxil 
2010 to 2011- 20 mg citalopram 
2013- 150 mg effexor xr, 300 mg by end of 2013; given lorazepam prn up to 3 mg per day

2014- 150 mg welbutin xr added to effexor 

2015- successfully tapered off of lorazepam by the end of the year

2016- reduction of effexor from 300, 150, 75, 37.5 from february to august

          reduction of welbutrin after effexor by taking every other day for a week, then every 3 days for two weeks until no longer taken by the end of august

due to horrible withdrawal, I tried reintroducing welbutrin back but had an adverse reaction

2017- currently no rx's