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Generic vs brand versions of antidepressants?


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#1 Meimeiquest

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Posted 05 June 2013 - 11:53 AM

http://www.fda.gov/d...s/ucm167991.htm What interested me was that the average absorption difference between different versions of the drugs was 3.5%...and that means some higher, some lower.
1st round Prozac 1989/90, clear depression symptoms. 2nd round Prozac started 1999 when admitted to dr. I was tired. Prozac pooped out, switch to Cymbalta 3/2006. Diagnosed with bipolar disorder due to mania 6/2006--then I was taken abruptly off Cymbalta and didn't know I had SSRI withdrawal. Lots of meds for my intractable "bipolar" symptoms.
Zyprexa started about 9/06, mostly 5mg. Tapered 4/12 through12/29/12
Wellbutrin. XL 300 mg started 1/07, tapered 1/18/13 through 7/8/13
Oxazepam mostly continuously since 6/06, 30mg since 12/12, tapered 1.17.14 through 8.26.15
11/06 Lithium 600mg twice daily, 2.2.14 400mg TID DIY liquid, 2.12.14 1150mg, 3.2.14 1100mg, 3.18.14 1075mg, 4/14 updose to 1100mg, 6.1.14 900 mg capsules 7.8.14 810mg, 8.17.14 725mg, 8.24.24 700mg...10.22.14 487.5mg, 3.9.15 475mg, 4.1.15 462.5mg 4.21.15 450mg 8.11.15 375mg, 11.28.15 362.5mg, back to 375mg four days later, 3.4.16 updose to 475 (too much going on to risk trouble)
9/4/13 Toprol-XL 25mg daily for sudden hypertension, tapered 11.12.13 through 5.3.14, last 10 days or so switched to atenolol
7.4.14 Started Walsh Protocol
56 years old

#2 NewMe

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Posted 20 April 2014 - 08:26 AM

I am tapering off brand effexor. 

 

My PDOC said generics contain at least 20% LESS potency than its' brand equivalent. My pharmacist says there is no potency difference.

 

I just went through a rough night and morning after having to take a generic (and staying on taper schedule) until I could pick up a brand RX.

 

This happened once before whereby I had taken generic when I ran out of brand (when I was on full dose, not tapering) back in December. I did not anticipate nor project concern of medication effectiveness between brand and generic. My body picked up on it and it felt just like CT withdrawal - in some ways it felt worse. 

 

I wonder if this is why the generic effexor  did not seem to have any effectiveness at all when I began taking it again  after four month being off paxil (CT). Once I switched to brand, I felt more stable. I had been taking generics approx 3 mos when I switched to brand last yr.

 

I apologize if this is an old topic but I could not find a post re this topic doing a search in the forum.

 

I have a comment and a question

 

I have worked so hard at attending a 12 step for general help and support (ind therapy last yr as I could afford) and truly trying my best to manage depression and panic along with the stress of my sister dying from cancer and me losing my home. I now take care my elderly parents and it is tough as hell being that my mom is an alcoholic (which is why I am in al anon). I am amazed at how scrambled, distorted and confused my brain became within hours of taking the generic. I try not to be angry and doubt that I will ever be ok w out this effing med - but I find it hard.

 

The question I have is - how are manufacturers of brand and generic allowed to vary in potency of this medication time and time again without being sanctioned for errors? How can it be every time I have tried generic it is vastly different in experience? Is the brand company dding something others are not when comparing brand to generics?

 

I know I sound paranoid but JFC - I feel like I am being fed addiction and not dependence on this crap. 

 

Thanks


I'M A WEANER!  :D 
atavan PRN ,Paxil approx 20 yrs ago for major depression
Switched to Klonopin PRN through to current
Paxil wore out
Changed to Effexor 
Depakote added
enormous weight gain - flat affect - led to depression - dropped depakote
Dropped Effexor, changed to Paxil 
PDoc added mixed salts amphetamines for ADHD - took for 2 yrs - was ok at first but had to cut as symptoms too intense -  then the crash was too much. STOPPED
Vyvanse started in 2013 (APRIL) - more smooth than IR amphetamine tabs---Have not used vyvanse daily in full amt since May 2013 

Paxil CT withdrawal 10/2012  :wacko:  Klonopin CT WD

Switched Klonopin to Xanax prn  - too strong

WD CT from XANAX after taking for a while - it was awful but can be done if you hold on!

Back to Klonopin PRN - working very hard to avoid taking it at all. 

Effexor 37.5 started 02/2013, 75mg by 03/2013, 150mg by 05/2012 (approx)  :blush:

Effexor 150mg 3/10/2014 Microtaper -3beads  :unsure:

3/11/2014-4beads ,3/12/14 - 5, 3/13/14 -6, 3/15/14 - 7, 3/18 - 8, 3/22 - 10, 3/24 - 12, 4/6 - 13, 4/7 - 14, 4/11 - 16 - on 4/19 ran out of brand took generic. Bad move. Back on brand on 4/20 and updosed 2 beads. 5/1 - 15, 5/6 - 16, 5/9 -17, 55/10 -17, 5/15 -18, 5/21 -19, 5/24 -20, 6/3 - 21, 6/6 -23, 6/13 -24,6/19- 25, 6/21 -26, 6/25 -27

6/28 -28, 6/29 -30, 7/3 -34, 7/8 -35, 7/17 -36, 7/30 -41,7/31 -42, 8/2 -43, 8/3 -44, 8/5 -45, 8/14 -48, 8/26-50, 9/24 -53, 10/24 -55, 12/1 -57, (lost the tally sheet, thus taper info for some of it), 4/19-63, 4/26-64, 4/30-65 Switched to wt reduction - now @ -.068, 7/14 -.070, August 2015 -.074, between Sept & October 10 -.077, Nov. -.078(feeling great), -.090 as of 1/10/16, down to  -.101 since January 2016 (it is now 6/24/16), -.105 as of 8/13/16
 
 

Ladies, please don't underestimate the possibility of perimenopause. The symptoms can be similar to, may intensify & in some cases mimic protracted w/d from ssri's & benzo's. 

 


#3 areyouthere

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Posted 20 April 2014 - 11:44 AM

Newme….. I cannot answer your question but I can tell you that for some people the generic just plain is not as effective. You MAY be one of them.

 

If the reason you are going generic is because your insurance Co. won't cover the brand name, your doctor CAN work with the insurance company as a special case by explaining to them that only the brand is effective for you & then the insurance CO. should pay.

 

RU


Fall 1995 xanax, zoloft. switched to Serzone
1996- spring 2003serzone/ xanax/ lightbox.
b]Fall 2003- Fall 2004? Lexapro 10 mg. Light box /4 mg. xanax.[/b]
2004 - Fall of 2009 10 mg Lex, 150 mg Wellbutrin XL % 4 mg xanax
November 2009- Sept. 2011 10 mg lex., 300 Well. XL, 4 mg Xanax [/b
Sept.2012- July 2012 20 mg Lex 300 Well. XL, 4 mg Xanax
My mantra " go slow & with the flow "
3/2/13.. Began equal dosing 5 Xs /day xanax, while simultaneously incorporating a 2.5 % drop ( from 3.5 mg/day to 3.4 mg/day)

4/6/13 dropped from 300 mg. Wellbutrin XL to 150 mg. Difficult but DONE! Down to 3.3 mg xanax/ day / 6/10/13 3 mg xanax/day; 7/15/2013 2.88mg xanax/day.
10/ 1/2013...... 2.5 mg xanax… ( switched to tablets again) WOO HOO!!!!!! Holding here… cont. with Lexapro.
1/ 2/2014.. tapered to 18mg ( by weight) of a 26 mg ( by weight) pill of 20 mg tab. lexapro. goal is 13mg (by weight OR 10 mg by ingredient content) and STOPPED. Feeling very down with unbalanced, unpredictable WD symptoms.
1/2/2014- ??? Taking a brain-healing break from tapering anything after actively tapering something for 1.5 years. So… daily doses as of 2/2/2014: 18 mg by weight Lex, 150 mg Well. XL, 2.5 mg xanax, down from 26 mg by weight Lex., 300 mg well. XL, 4 mg xanax in August, 2012. I'll take it. :) 5/8/14 started equivalent dose liquid./ tabs. 5/13/14 1.5 % cut.

#4 NewMe

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Posted 20 April 2014 - 12:21 PM

Thank you for the reply.

 

I had been able to get the meds with the manu assistance program - but have just moved and no doctor - only had one script left and some generics. Have to find a new doc and reapply for med assistance from the company that enabled me to become dependent on this crap. 


I'M A WEANER!  :D 
atavan PRN ,Paxil approx 20 yrs ago for major depression
Switched to Klonopin PRN through to current
Paxil wore out
Changed to Effexor 
Depakote added
enormous weight gain - flat affect - led to depression - dropped depakote
Dropped Effexor, changed to Paxil 
PDoc added mixed salts amphetamines for ADHD - took for 2 yrs - was ok at first but had to cut as symptoms too intense -  then the crash was too much. STOPPED
Vyvanse started in 2013 (APRIL) - more smooth than IR amphetamine tabs---Have not used vyvanse daily in full amt since May 2013 

Paxil CT withdrawal 10/2012  :wacko:  Klonopin CT WD

Switched Klonopin to Xanax prn  - too strong

WD CT from XANAX after taking for a while - it was awful but can be done if you hold on!

Back to Klonopin PRN - working very hard to avoid taking it at all. 

Effexor 37.5 started 02/2013, 75mg by 03/2013, 150mg by 05/2012 (approx)  :blush:

Effexor 150mg 3/10/2014 Microtaper -3beads  :unsure:

3/11/2014-4beads ,3/12/14 - 5, 3/13/14 -6, 3/15/14 - 7, 3/18 - 8, 3/22 - 10, 3/24 - 12, 4/6 - 13, 4/7 - 14, 4/11 - 16 - on 4/19 ran out of brand took generic. Bad move. Back on brand on 4/20 and updosed 2 beads. 5/1 - 15, 5/6 - 16, 5/9 -17, 55/10 -17, 5/15 -18, 5/21 -19, 5/24 -20, 6/3 - 21, 6/6 -23, 6/13 -24,6/19- 25, 6/21 -26, 6/25 -27

6/28 -28, 6/29 -30, 7/3 -34, 7/8 -35, 7/17 -36, 7/30 -41,7/31 -42, 8/2 -43, 8/3 -44, 8/5 -45, 8/14 -48, 8/26-50, 9/24 -53, 10/24 -55, 12/1 -57, (lost the tally sheet, thus taper info for some of it), 4/19-63, 4/26-64, 4/30-65 Switched to wt reduction - now @ -.068, 7/14 -.070, August 2015 -.074, between Sept & October 10 -.077, Nov. -.078(feeling great), -.090 as of 1/10/16, down to  -.101 since January 2016 (it is now 6/24/16), -.105 as of 8/13/16
 
 

Ladies, please don't underestimate the possibility of perimenopause. The symptoms can be similar to, may intensify & in some cases mimic protracted w/d from ssri's & benzo's. 

 


#5 Altostrata

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Posted 21 April 2014 - 12:30 PM

There are some variations between generics and name brand drugs, and there are variations among generic brands, too.

Some people are sensitive to the differences and some not.
This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#6 NewMe

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Posted 21 April 2014 - 02:56 PM

They may as well have put gerbil shavings in the generic for the lack of effectiveness I experienced. Good excuse to get a gerbil. 


I'M A WEANER!  :D 
atavan PRN ,Paxil approx 20 yrs ago for major depression
Switched to Klonopin PRN through to current
Paxil wore out
Changed to Effexor 
Depakote added
enormous weight gain - flat affect - led to depression - dropped depakote
Dropped Effexor, changed to Paxil 
PDoc added mixed salts amphetamines for ADHD - took for 2 yrs - was ok at first but had to cut as symptoms too intense -  then the crash was too much. STOPPED
Vyvanse started in 2013 (APRIL) - more smooth than IR amphetamine tabs---Have not used vyvanse daily in full amt since May 2013 

Paxil CT withdrawal 10/2012  :wacko:  Klonopin CT WD

Switched Klonopin to Xanax prn  - too strong

WD CT from XANAX after taking for a while - it was awful but can be done if you hold on!

Back to Klonopin PRN - working very hard to avoid taking it at all. 

Effexor 37.5 started 02/2013, 75mg by 03/2013, 150mg by 05/2012 (approx)  :blush:

Effexor 150mg 3/10/2014 Microtaper -3beads  :unsure:

3/11/2014-4beads ,3/12/14 - 5, 3/13/14 -6, 3/15/14 - 7, 3/18 - 8, 3/22 - 10, 3/24 - 12, 4/6 - 13, 4/7 - 14, 4/11 - 16 - on 4/19 ran out of brand took generic. Bad move. Back on brand on 4/20 and updosed 2 beads. 5/1 - 15, 5/6 - 16, 5/9 -17, 55/10 -17, 5/15 -18, 5/21 -19, 5/24 -20, 6/3 - 21, 6/6 -23, 6/13 -24,6/19- 25, 6/21 -26, 6/25 -27

6/28 -28, 6/29 -30, 7/3 -34, 7/8 -35, 7/17 -36, 7/30 -41,7/31 -42, 8/2 -43, 8/3 -44, 8/5 -45, 8/14 -48, 8/26-50, 9/24 -53, 10/24 -55, 12/1 -57, (lost the tally sheet, thus taper info for some of it), 4/19-63, 4/26-64, 4/30-65 Switched to wt reduction - now @ -.068, 7/14 -.070, August 2015 -.074, between Sept & October 10 -.077, Nov. -.078(feeling great), -.090 as of 1/10/16, down to  -.101 since January 2016 (it is now 6/24/16), -.105 as of 8/13/16
 
 

Ladies, please don't underestimate the possibility of perimenopause. The symptoms can be similar to, may intensify & in some cases mimic protracted w/d from ssri's & benzo's. 

 


#7 btdt

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Posted 21 April 2014 - 07:37 PM

I could not take the generic and my pharmacy switched it without telling me a melt down was what gave me the heads up... the pill looked the same I had taken it for wks.  

When I asked the pharmacist he said they were supposed to be the same active ingredient I told him NEVER change any of my drugs again without talking to me about it first. I was amazed it was legal for them to do this without telling me.  There was a case on the news here a few months ago of how a generic had messed up a disabled person severely affecting his life without a word to the care taking parents who had power over his daily living. They made the news but like most things that make the news doubt anything changed.  


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#8 Lexy

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Posted 22 April 2014 - 08:05 AM

Newme

I was taking generic immediate release effexor since Aug 2012. I was having vertigo and headaches 24/7.
I asked my doc to switch to brand effexor XR. I do believe they have a variance in potency. The vertigo and headaches were gone almost immediately however mood swings, and anxiety have ramped up.
I proceeded to decrease the XR and add more of generic to modify these effects. These wds/side effects have dissipated somewhat.

I feel if I would decrease the generic i would not feel wds as much but
in the future would like to convert the generic into liquid.

Not sure if I am making any sense in how I'm tapering (using both generic IR & brand XR) but I was so tired of vertigo and headaches going on for months at a time.

I wonder which is the least harmful as far as withdrawals go.
Started Effexor August 2012 Sept'12-150mg=extreme anxiety Oct'12 cut half-75mg severe wds
Feb 2013 68.5mg. Mar'13- 65mg. Apr'13-59mg. May'13-57mg. June '13-52mg Aug'13 49.75mg.
Sep'13-48.75. Nov'13-47mg Dec'13-45..5mg
May 2014 42mg. Jun'14 40mg (depressive mood started). Aug'14 -40mg/ started brintellix 2.5mg
Oct '14 -39 Nov'14 36.89 Dec'14 34.45
Jan 2015- 31 Feb'15 29mg. Mar'15 26.72. Apr'15 24.48. May'15 22.31mg. Jun'15 20.30mg
Aug'15-18.89. Oct'15 16.96. Nov/16- 16.10. Dec/15- 15mg
Jan 2016-14.22. May'16 11.45. Aug'16-9.60. Sep/16- 8.88mg. Oct/16- 8.39mg. Nov/16- 8.13. Dec/16- 7.89

#9 Altostrata

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Posted 22 April 2014 - 04:42 PM

Lexy, you changed from generic immediate-release to brand-name extended-release. Which do you think had the most effect, the second drug being brand-name or extended-release? You're comparing apples and oranges.

Not only that, you varied your dosage in a very confusing way. It's impossible to tell what caused what or what was the benefit.

I don't think your example shows anything about generic vs brand-name.

All that aside, I'm glad your headaches have gone away.
This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#10 Lexy

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Posted 29 April 2014 - 05:13 PM

You are right I was comparing apples to oranges however, 

I do believe that for me,  Effexor XR took away the vertigo and headaches.  This happened the following day I increased  the XR part of the dosage. 


Started Effexor August 2012 Sept'12-150mg=extreme anxiety Oct'12 cut half-75mg severe wds
Feb 2013 68.5mg. Mar'13- 65mg. Apr'13-59mg. May'13-57mg. June '13-52mg Aug'13 49.75mg.
Sep'13-48.75. Nov'13-47mg Dec'13-45..5mg
May 2014 42mg. Jun'14 40mg (depressive mood started). Aug'14 -40mg/ started brintellix 2.5mg
Oct '14 -39 Nov'14 36.89 Dec'14 34.45
Jan 2015- 31 Feb'15 29mg. Mar'15 26.72. Apr'15 24.48. May'15 22.31mg. Jun'15 20.30mg
Aug'15-18.89. Oct'15 16.96. Nov/16- 16.10. Dec/15- 15mg
Jan 2016-14.22. May'16 11.45. Aug'16-9.60. Sep/16- 8.88mg. Oct/16- 8.39mg. Nov/16- 8.13. Dec/16- 7.89

#11 Altostrata

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Posted 29 April 2014 - 06:25 PM

That may be true, Lexy. I'm glad it did that for you.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#12 LexAnger

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Posted 02 May 2014 - 07:47 AM

I echo the difference in generic vs name brand for lexopro. I was switched to generic 2 yrs ago without knowing. Struggled with side effects and started tapering from it 1 yr ago ended up with nix of side effects and , had to stop tapering when I was at 2.5 mg. pain all over ESP jaw, head ever since and only started seeing some lights after 6 months back to name brand.
<p>2009 Mar.: lexapro 10mg for headache for 2 weeks.2009-2012: on and off 1/4 to 1/3 of 10mg2012 June--2013 Jan,: 1/4-1/3 of 10mg generic, bad jaw pain2013 Jan-Mar: 10 mg generic. severe jaw and head pain; Mar--Aug. started tapering (liquid ever since) from 10 to 5 (one step) then gradually down to 2.25 mg, first ever panic attack, severe head/jaw pain2013 Aug.: back to 2.75 mg; Nov: back to Brand Lex. 2.75mg -- 3mg, slight improvement with pain2014 June: stopped PPI, head pressure/numbness. up-dosed 4.5mg, severe reaction mental symptoms added on2014 Aug--2015 Aug: Micro taper down to 3.2mg, .025mg (<1%) cut holding 2-3 weeks.2015 Aug 15th, Accidental one dose of 4.2mg. worsening brain non-functional, swollen head, body, coma like, DR2016 Feb., started fast taper for the drug toxicity caused by the one dose of 4.2mg, dosing 10am through 11 pm everyday2/13--3.2mg, 3/15-- 2.9mg, 4/19-- 2.6mg, 6/26--2.2mg, 7/22 --1.9mg, 8/16--1.8mg,8/31--1.7m g, 9/13--1.6mg, 9/27--1.5mg, 10/8--1.4mg, 10/14--1.3mg, 11/1--1.2mg, 11/29--1.1mg, 12/12--1mg, 12/22--0.9mg2017: 1/7--0.8mg, 1/15--0.7mg, 1/17--0.6mg, 1/20--0.52, 1/21--0.4mg, 1/22--0.26, 1/23--0.2, sliding Down to 0.13mg by 2/13, then 0.07mg since 2/18, 0.06mg 2/20-3/17, 0.13mg 3/18

#13 Lexy

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Posted 02 May 2014 - 01:20 PM

I agree there is a difference in generic vs brand.
My brother is on Wellbutrin and recently moved to a different state. He found a pdoc which gave him rx. He noticed the the bottle was different, however he started taking the generic a few days later he called doctor to request the brand.
He's been complaining of feeling anxiety after this I'm not sure if it was the generic. He's been on Wellbutrin for about 5 years at 300mg.
He is not tapering. He does believe it has helped him.
Started Effexor August 2012 Sept'12-150mg=extreme anxiety Oct'12 cut half-75mg severe wds
Feb 2013 68.5mg. Mar'13- 65mg. Apr'13-59mg. May'13-57mg. June '13-52mg Aug'13 49.75mg.
Sep'13-48.75. Nov'13-47mg Dec'13-45..5mg
May 2014 42mg. Jun'14 40mg (depressive mood started). Aug'14 -40mg/ started brintellix 2.5mg
Oct '14 -39 Nov'14 36.89 Dec'14 34.45
Jan 2015- 31 Feb'15 29mg. Mar'15 26.72. Apr'15 24.48. May'15 22.31mg. Jun'15 20.30mg
Aug'15-18.89. Oct'15 16.96. Nov/16- 16.10. Dec/15- 15mg
Jan 2016-14.22. May'16 11.45. Aug'16-9.60. Sep/16- 8.88mg. Oct/16- 8.39mg. Nov/16- 8.13. Dec/16- 7.89

#14 LexAnger

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Posted 02 May 2014 - 06:35 PM

One prove is that I experience WD when switching back to name brand without any other changes. Tats how different the two could be!
<p>2009 Mar.: lexapro 10mg for headache for 2 weeks.2009-2012: on and off 1/4 to 1/3 of 10mg2012 June--2013 Jan,: 1/4-1/3 of 10mg generic, bad jaw pain2013 Jan-Mar: 10 mg generic. severe jaw and head pain; Mar--Aug. started tapering (liquid ever since) from 10 to 5 (one step) then gradually down to 2.25 mg, first ever panic attack, severe head/jaw pain2013 Aug.: back to 2.75 mg; Nov: back to Brand Lex. 2.75mg -- 3mg, slight improvement with pain2014 June: stopped PPI, head pressure/numbness. up-dosed 4.5mg, severe reaction mental symptoms added on2014 Aug--2015 Aug: Micro taper down to 3.2mg, .025mg (<1%) cut holding 2-3 weeks.2015 Aug 15th, Accidental one dose of 4.2mg. worsening brain non-functional, swollen head, body, coma like, DR2016 Feb., started fast taper for the drug toxicity caused by the one dose of 4.2mg, dosing 10am through 11 pm everyday2/13--3.2mg, 3/15-- 2.9mg, 4/19-- 2.6mg, 6/26--2.2mg, 7/22 --1.9mg, 8/16--1.8mg,8/31--1.7m g, 9/13--1.6mg, 9/27--1.5mg, 10/8--1.4mg, 10/14--1.3mg, 11/1--1.2mg, 11/29--1.1mg, 12/12--1mg, 12/22--0.9mg2017: 1/7--0.8mg, 1/15--0.7mg, 1/17--0.6mg, 1/20--0.52, 1/21--0.4mg, 1/22--0.26, 1/23--0.2, sliding Down to 0.13mg by 2/13, then 0.07mg since 2/18, 0.06mg 2/20-3/17, 0.13mg 3/18

#15 btdt

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Posted 04 May 2014 - 03:11 PM

I agree they for me there was a huge difference between the brand name and generic... whichever you on don't switch.  As your body is use to it. 


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#16 NewMe

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Posted 06 May 2014 - 05:59 PM

I could not take the generic and my pharmacy switched it without telling me a melt down was what gave me the heads up... the pill looked the same I had taken it for wks.  

When I asked the pharmacist he said they were supposed to be the same active ingredient I told him NEVER change any of my drugs again without talking to me about it first. I was amazed it was legal for them to do this without telling me.  There was a case on the news here a few months ago of how a generic had messed up a disabled person severely affecting his life without a word to the care taking parents who had power over his daily living. They made the news but like most things that make the news doubt anything changed.  

Sorry so late in replying - 

 

I too, am shocked (disgusted) that this is legal to do without informed consent. The more I red bout psychopharma and realizing the insanity of it in being sold as "helping" people - the angrier I become at the many losses in my OWN life due to the meds. and lies.

 

My own Pdoc had said the generics offer 20% LESS of the effective drug though his RECEPTIONIST quipped that "oh yeah - he tells people that - but thats not true."...further backed by pharmacists who have insisted there is no difference.

 

Now that I am informed about FDA's role in approving generics based on manu "STUDIES" and trials - I see with the recentlink giaK supplied in the fora (Wellbutrin drug recall), that big pharma FDA and PDOCS are destroying lives with chemical straightjackets as if OFSA (one size fits all - IF AT ALL!!!!!!!!!). Has yet to be PROVEN. 


I'M A WEANER!  :D 
atavan PRN ,Paxil approx 20 yrs ago for major depression
Switched to Klonopin PRN through to current
Paxil wore out
Changed to Effexor 
Depakote added
enormous weight gain - flat affect - led to depression - dropped depakote
Dropped Effexor, changed to Paxil 
PDoc added mixed salts amphetamines for ADHD - took for 2 yrs - was ok at first but had to cut as symptoms too intense -  then the crash was too much. STOPPED
Vyvanse started in 2013 (APRIL) - more smooth than IR amphetamine tabs---Have not used vyvanse daily in full amt since May 2013 

Paxil CT withdrawal 10/2012  :wacko:  Klonopin CT WD

Switched Klonopin to Xanax prn  - too strong

WD CT from XANAX after taking for a while - it was awful but can be done if you hold on!

Back to Klonopin PRN - working very hard to avoid taking it at all. 

Effexor 37.5 started 02/2013, 75mg by 03/2013, 150mg by 05/2012 (approx)  :blush:

Effexor 150mg 3/10/2014 Microtaper -3beads  :unsure:

3/11/2014-4beads ,3/12/14 - 5, 3/13/14 -6, 3/15/14 - 7, 3/18 - 8, 3/22 - 10, 3/24 - 12, 4/6 - 13, 4/7 - 14, 4/11 - 16 - on 4/19 ran out of brand took generic. Bad move. Back on brand on 4/20 and updosed 2 beads. 5/1 - 15, 5/6 - 16, 5/9 -17, 55/10 -17, 5/15 -18, 5/21 -19, 5/24 -20, 6/3 - 21, 6/6 -23, 6/13 -24,6/19- 25, 6/21 -26, 6/25 -27

6/28 -28, 6/29 -30, 7/3 -34, 7/8 -35, 7/17 -36, 7/30 -41,7/31 -42, 8/2 -43, 8/3 -44, 8/5 -45, 8/14 -48, 8/26-50, 9/24 -53, 10/24 -55, 12/1 -57, (lost the tally sheet, thus taper info for some of it), 4/19-63, 4/26-64, 4/30-65 Switched to wt reduction - now @ -.068, 7/14 -.070, August 2015 -.074, between Sept & October 10 -.077, Nov. -.078(feeling great), -.090 as of 1/10/16, down to  -.101 since January 2016 (it is now 6/24/16), -.105 as of 8/13/16
 
 

Ladies, please don't underestimate the possibility of perimenopause. The symptoms can be similar to, may intensify & in some cases mimic protracted w/d from ssri's & benzo's. 

 


#17 NewMe

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Posted 06 May 2014 - 06:04 PM

After reading more personal experiences on here - online - and becoming way more informed than before, I am disgusted, angry, fearful and generally at unrest watching psuedoscience hard at work  putting people into chemical straightjackets. 


I'M A WEANER!  :D 
atavan PRN ,Paxil approx 20 yrs ago for major depression
Switched to Klonopin PRN through to current
Paxil wore out
Changed to Effexor 
Depakote added
enormous weight gain - flat affect - led to depression - dropped depakote
Dropped Effexor, changed to Paxil 
PDoc added mixed salts amphetamines for ADHD - took for 2 yrs - was ok at first but had to cut as symptoms too intense -  then the crash was too much. STOPPED
Vyvanse started in 2013 (APRIL) - more smooth than IR amphetamine tabs---Have not used vyvanse daily in full amt since May 2013 

Paxil CT withdrawal 10/2012  :wacko:  Klonopin CT WD

Switched Klonopin to Xanax prn  - too strong

WD CT from XANAX after taking for a while - it was awful but can be done if you hold on!

Back to Klonopin PRN - working very hard to avoid taking it at all. 

Effexor 37.5 started 02/2013, 75mg by 03/2013, 150mg by 05/2012 (approx)  :blush:

Effexor 150mg 3/10/2014 Microtaper -3beads  :unsure:

3/11/2014-4beads ,3/12/14 - 5, 3/13/14 -6, 3/15/14 - 7, 3/18 - 8, 3/22 - 10, 3/24 - 12, 4/6 - 13, 4/7 - 14, 4/11 - 16 - on 4/19 ran out of brand took generic. Bad move. Back on brand on 4/20 and updosed 2 beads. 5/1 - 15, 5/6 - 16, 5/9 -17, 55/10 -17, 5/15 -18, 5/21 -19, 5/24 -20, 6/3 - 21, 6/6 -23, 6/13 -24,6/19- 25, 6/21 -26, 6/25 -27

6/28 -28, 6/29 -30, 7/3 -34, 7/8 -35, 7/17 -36, 7/30 -41,7/31 -42, 8/2 -43, 8/3 -44, 8/5 -45, 8/14 -48, 8/26-50, 9/24 -53, 10/24 -55, 12/1 -57, (lost the tally sheet, thus taper info for some of it), 4/19-63, 4/26-64, 4/30-65 Switched to wt reduction - now @ -.068, 7/14 -.070, August 2015 -.074, between Sept & October 10 -.077, Nov. -.078(feeling great), -.090 as of 1/10/16, down to  -.101 since January 2016 (it is now 6/24/16), -.105 as of 8/13/16
 
 

Ladies, please don't underestimate the possibility of perimenopause. The symptoms can be similar to, may intensify & in some cases mimic protracted w/d from ssri's & benzo's. 

 


#18 btdt

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Posted 09 May 2014 - 03:50 AM

After reading more personal experiences on here - online - and becoming way more informed than before, I am disgusted, angry, fearful and generally at unrest watching psuedoscience hard at work  putting people into chemical straightjackets. 

I see you are new. 

This is something most of us have come to know sooner or later sadly all the emotions that come with the knowing hamper you healing... so if you can please try to step back from this just now and focus on your healing.  I know that is a tall order when in withdrawal but it is paramount that you heal that is more important than the truth right now... the truth will still be here when you well it has been here for years and is not going anywhere. 

I wish you peace 

peace is the state in which our bodies heal best....

peace.


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#19 NewMe

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Posted 10 May 2014 - 11:08 AM

 

After reading more personal experiences on here - online - and becoming way more informed than before, I am disgusted, angry, fearful and generally at unrest watching psuedoscience hard at work  putting people into chemical straightjackets. 

I see you are new. 

This is something most of us have come to know sooner or later sadly all the emotions that come with the knowing hamper you healing... so if you can please try to step back from this just now and focus on your healing.  I know that is a tall order when in withdrawal but it is paramount that you heal that is more important than the truth right now... the truth will still be here when you well it has been here for years and is not going anywhere. 

I wish you peace 

peace is the state in which our bodies heal best....

peace.

 

Yes I am new to this board but not new to coming off vi tapering from SSRIs - unfortunately.

 

Unable to find work despite college degree and a return for a tech degree - I cannot afford brand - hence the need to switch to generic. I was just turned down for assistance due to skewed incorrect presumption about income.Had to draw the last of my IRA to survive - and it wasnt much - but with a astounding tax penalty that did more harm than good. 

 

I am not in withdrawal right now. Its not a return of my depressive state. It is pure unadulterated disgust with the lies I was sold and an RX now dependent on. The day I have to choose over eating food and dependence on an RX that never did anything to help and costs more than I spend on gas in a month is outrageous. 

 

There is no reason a generic should provide less quality though the discontinuation syndrome is very very real when I have taken it. I had anticipatory anxiety in the switch presuming the medicine potency was the same. I was told there is no difference by the pharmacist as well as a second MD I went to. Considering the unfavorable scenarios people go through in DS, the disparity is something that can cost someone their mental well being and possibly their life. 


I'M A WEANER!  :D 
atavan PRN ,Paxil approx 20 yrs ago for major depression
Switched to Klonopin PRN through to current
Paxil wore out
Changed to Effexor 
Depakote added
enormous weight gain - flat affect - led to depression - dropped depakote
Dropped Effexor, changed to Paxil 
PDoc added mixed salts amphetamines for ADHD - took for 2 yrs - was ok at first but had to cut as symptoms too intense -  then the crash was too much. STOPPED
Vyvanse started in 2013 (APRIL) - more smooth than IR amphetamine tabs---Have not used vyvanse daily in full amt since May 2013 

Paxil CT withdrawal 10/2012  :wacko:  Klonopin CT WD

Switched Klonopin to Xanax prn  - too strong

WD CT from XANAX after taking for a while - it was awful but can be done if you hold on!

Back to Klonopin PRN - working very hard to avoid taking it at all. 

Effexor 37.5 started 02/2013, 75mg by 03/2013, 150mg by 05/2012 (approx)  :blush:

Effexor 150mg 3/10/2014 Microtaper -3beads  :unsure:

3/11/2014-4beads ,3/12/14 - 5, 3/13/14 -6, 3/15/14 - 7, 3/18 - 8, 3/22 - 10, 3/24 - 12, 4/6 - 13, 4/7 - 14, 4/11 - 16 - on 4/19 ran out of brand took generic. Bad move. Back on brand on 4/20 and updosed 2 beads. 5/1 - 15, 5/6 - 16, 5/9 -17, 55/10 -17, 5/15 -18, 5/21 -19, 5/24 -20, 6/3 - 21, 6/6 -23, 6/13 -24,6/19- 25, 6/21 -26, 6/25 -27

6/28 -28, 6/29 -30, 7/3 -34, 7/8 -35, 7/17 -36, 7/30 -41,7/31 -42, 8/2 -43, 8/3 -44, 8/5 -45, 8/14 -48, 8/26-50, 9/24 -53, 10/24 -55, 12/1 -57, (lost the tally sheet, thus taper info for some of it), 4/19-63, 4/26-64, 4/30-65 Switched to wt reduction - now @ -.068, 7/14 -.070, August 2015 -.074, between Sept & October 10 -.077, Nov. -.078(feeling great), -.090 as of 1/10/16, down to  -.101 since January 2016 (it is now 6/24/16), -.105 as of 8/13/16
 
 

Ladies, please don't underestimate the possibility of perimenopause. The symptoms can be similar to, may intensify & in some cases mimic protracted w/d from ssri's & benzo's. 

 


#20 NewMe

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Posted 10 May 2014 - 11:14 AM

Article is somewhat dated but really helps - 

http://www.psycholog...do-when-it-does

 

..."Generic drugs are supposed to be deemed "bioequivalent" by the FDA, which means they should have the same amount of active ingredient as their brand counterparts as demonstrated on healthy volunteers.  They do not test whether they actually work or not (ie efficacy/effectiveness).  A review of studies comparing bioequivalence and therapeutic effectiveness of generic vs. brand psychoactive drugs concluded that bioequivalence and effectiveness are not necessarily the same, and recommended more rigorous testing for toleratibility and efficacy in actual patients--not just healthy volunteers (Borgheini, 2003)...."

...."Just because a drug company is headquartered somewhere does not mean the drugs are manufactured there.  They may be outsourced to more than one location, and oversight may be poor. 

76389-67002.jpg

 

Generic drugs have different fillers and binders that many people point to as the culprit when a generic doesn't work as well.   Experts speculate that these chemicals may interfere with absorption, or cause adverse allergic-type reactions that increase inflammation in the nervous system. "


I'M A WEANER!  :D 
atavan PRN ,Paxil approx 20 yrs ago for major depression
Switched to Klonopin PRN through to current
Paxil wore out
Changed to Effexor 
Depakote added
enormous weight gain - flat affect - led to depression - dropped depakote
Dropped Effexor, changed to Paxil 
PDoc added mixed salts amphetamines for ADHD - took for 2 yrs - was ok at first but had to cut as symptoms too intense -  then the crash was too much. STOPPED
Vyvanse started in 2013 (APRIL) - more smooth than IR amphetamine tabs---Have not used vyvanse daily in full amt since May 2013 

Paxil CT withdrawal 10/2012  :wacko:  Klonopin CT WD

Switched Klonopin to Xanax prn  - too strong

WD CT from XANAX after taking for a while - it was awful but can be done if you hold on!

Back to Klonopin PRN - working very hard to avoid taking it at all. 

Effexor 37.5 started 02/2013, 75mg by 03/2013, 150mg by 05/2012 (approx)  :blush:

Effexor 150mg 3/10/2014 Microtaper -3beads  :unsure:

3/11/2014-4beads ,3/12/14 - 5, 3/13/14 -6, 3/15/14 - 7, 3/18 - 8, 3/22 - 10, 3/24 - 12, 4/6 - 13, 4/7 - 14, 4/11 - 16 - on 4/19 ran out of brand took generic. Bad move. Back on brand on 4/20 and updosed 2 beads. 5/1 - 15, 5/6 - 16, 5/9 -17, 55/10 -17, 5/15 -18, 5/21 -19, 5/24 -20, 6/3 - 21, 6/6 -23, 6/13 -24,6/19- 25, 6/21 -26, 6/25 -27

6/28 -28, 6/29 -30, 7/3 -34, 7/8 -35, 7/17 -36, 7/30 -41,7/31 -42, 8/2 -43, 8/3 -44, 8/5 -45, 8/14 -48, 8/26-50, 9/24 -53, 10/24 -55, 12/1 -57, (lost the tally sheet, thus taper info for some of it), 4/19-63, 4/26-64, 4/30-65 Switched to wt reduction - now @ -.068, 7/14 -.070, August 2015 -.074, between Sept & October 10 -.077, Nov. -.078(feeling great), -.090 as of 1/10/16, down to  -.101 since January 2016 (it is now 6/24/16), -.105 as of 8/13/16
 
 

Ladies, please don't underestimate the possibility of perimenopause. The symptoms can be similar to, may intensify & in some cases mimic protracted w/d from ssri's & benzo's. 

 


#21 btdt

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Posted 10 May 2014 - 07:22 PM

 

 

After reading more personal experiences on here - online - and becoming way more informed than before, I am disgusted, angry, fearful and generally at unrest watching psuedoscience hard at work  putting people into chemical straightjackets. 

I see you are new. 

This is something most of us have come to know sooner or later sadly all the emotions that come with the knowing hamper you healing... so if you can please try to step back from this just now and focus on your healing.  I know that is a tall order when in withdrawal but it is paramount that you heal that is more important than the truth right now... the truth will still be here when you well it has been here for years and is not going anywhere. 

I wish you peace 

peace is the state in which our bodies heal best....

peace.

 

Yes I am new to this board but not new to coming off vi tapering from SSRIs - unfortunately.

 

Unable to find work despite college degree and a return for a tech degree - I cannot afford brand - hence the need to switch to generic. I was just turned down for assistance due to skewed incorrect presumption about income.Had to draw the last of my IRA to survive - and it wasnt much - but with a astounding tax penalty that did more harm than good. 

 

I am not in withdrawal right now. Its not a return of my depressive state. It is pure unadulterated disgust with the lies I was sold and an RX now dependent on. The day I have to choose over eating food and dependence on an RX that never did anything to help and costs more than I spend on gas in a month is outrageous. 

 

There is no reason a generic should provide less quality though the discontinuation syndrome is very very real when I have taken it. I had anticipatory anxiety in the switch presuming the medicine potency was the same. I was told there is no difference by the pharmacist as well as a second MD I went to. Considering the unfavorable scenarios people go through in DS, the disparity is something that can cost someone their mental well being and possibly their life. 

 

I don't care what they say is in the drug or how they are suppose to be the same the meltdown I had was not because I had anxiety about the drug switch as I did not notice it had been changed till after the damage was done.  

I no longer have a problem going against the norm or what they tell me as I know what I know and generics do not act the same inside my body as the brain name no matter what crap they are trying to sell... I am not buying.


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#22 newtonsmom2000

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Posted 19 May 2014 - 04:32 PM

Hello there,

 

My own withdrawal is progressing... for the last year with some complications but I've survived them.

 

My question isn't about me, though- it's about my husband who is taking Pristiq.  He's been on it for quite a few years- I think more than 5 years.  He recently retired and is now using a Medicare Supplemental Drug program through an insurance company.  He was ignorant of how much he was going to be paying for his antidepressant.  (This is in part why I wanted to get off these drugs).  

 

He checked with Canada Pharmacy and they have a generic from India- I did not know you can ask them where the country of origin is for any drugs you get from them.  The price for this drug is $300.00 less than what he is now paying for a 90 day supply.

 

He's pretty bullheaded and won't listen to me when I tell him I don't think this is a good idea.  I did a little research and the advice I gleaned did not recommend this alternative.  

 

Has anyone here tried this?  I don't have any other dependable or bias free resource I feel is trustworthy.  Your input is much appreciated

 

Newtons Mom


Effexor free 12/17/16

Clonazepam .75 mg

 

 


#23 Altostrata

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Posted 19 May 2014 - 04:46 PM

Is the manufacturer Ranbaxy? It is FDA-approved http://dailymed.nlm....a3-a3d8d4c4d222

Also see https://www.healthwa...sult/?q=pristiq
This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

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#24 Harmonica

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Posted 20 May 2014 - 12:18 AM

I can't say I noticed any major difference between effexor XR and the generic until I started bead counting to try to taper off. There seemed to be a wide discrepancy with the size of the beads. The effexor beads seemed much bigger so if I was removing 100 beads from an effexor XR capsule then trying to remove 100 beads from a generic was never going to be the same. This led to some unpleasant side effects so now I insist on effexor only.


Slowly coming off 150 mg venlafaxine a day after nine years on it. Removing a small amount of beads from a capsule each month. Then I stabilise and remove another small amount. Not as precise as the 10% method but so far so good.  Any help/advice is greatly appreciated.


#25 mammaP

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Posted 21 May 2014 - 12:04 PM

I can't say I noticed any major difference between effexor XR and the generic until I started bead counting to try to taper off. There seemed to be a wide discrepancy with the size of the beads. The effexor beads seemed much bigger so if I was removing 100 beads from an effexor XR capsule then trying to remove 100 beads from a generic was never going to be the same. This led to some unpleasant side effects so now I insist on effexor only.

Harmonica are the effexor beads all the same size? I had some effexor capsules and the beads were all different sizes, more like chips than beads. I also had generic (rodomel, which is what I'm tapering.)  The rodomel are more uniform in sizethan effexor but still not all the same.  It's a pain trying to get them all the same consistently! The effexor was an old pack though, they might have changed now. Some chips were like sugar crystals! 


**I am not a medical professional, if in doubt please consult a doctor with withdrawal knowledge.

 

See how to create a signature here http://survivingantidepressants.org/index.php?/topic/12364-please-put-your-withdrawal-history-in-your-signature/

 

Many drugs for many years, prescribed diazepam first 1973, took occasionally. 3 or 4 tricyclics  for short periods.

1993 had a breakdown leading to 10 years of drug experiments with all classes of psych drugs.

2002  effexor. 

Tapered by counting beads from March 2012 to March 2013, ending with 5 beads.

Withdrawal April 2013 . Reinstated 5 beads reduced to 4 beads May 2013

Restarted taper  Nov 2013  

OFF EFFEXOR Feb 2015    :D 

 

Also tapered atenolol and omeprazole Dec 2013 - May 2014

 

Tapering tramadol, Feb 2015 100mg , March 2015 50mg -hold- Feb2016 46mg  March 8 2016 45 April 44mg  May 11  43mg June 14 42mg

Taking fish oil, magnesium, pro biotic.

 

My story http://survivinganti...king-in/page-33

 

Lesson learned, slow down taper at lower doses. Taper no more than 10% of CURRENT dose if possible

 

Following every sunset is a brand new day


#26 newtonsmom2000

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Posted 25 May 2014 - 05:27 PM

Alto, If I didn't respond, thank you so very much.  I passed the information along to my hubby.  I knew someone here would know.  I thought I posted a response but I don't think it made it.  Sorry.  Thanks again.

 

Newtons Mom


Effexor free 12/17/16

Clonazepam .75 mg

 

 


#27 Lexy

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Posted 28 May 2014 - 08:45 AM

Have you tried buying a scale and weighing the beads?
Started Effexor August 2012 Sept'12-150mg=extreme anxiety Oct'12 cut half-75mg severe wds
Feb 2013 68.5mg. Mar'13- 65mg. Apr'13-59mg. May'13-57mg. June '13-52mg Aug'13 49.75mg.
Sep'13-48.75. Nov'13-47mg Dec'13-45..5mg
May 2014 42mg. Jun'14 40mg (depressive mood started). Aug'14 -40mg/ started brintellix 2.5mg
Oct '14 -39 Nov'14 36.89 Dec'14 34.45
Jan 2015- 31 Feb'15 29mg. Mar'15 26.72. Apr'15 24.48. May'15 22.31mg. Jun'15 20.30mg
Aug'15-18.89. Oct'15 16.96. Nov/16- 16.10. Dec/15- 15mg
Jan 2016-14.22. May'16 11.45. Aug'16-9.60. Sep/16- 8.88mg. Oct/16- 8.39mg. Nov/16- 8.13. Dec/16- 7.89

#28 Altostrata

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Posted 29 May 2014 - 03:12 PM

Google and ye shall find.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

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#29 LexAnger

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Posted 29 May 2014 - 03:27 PM

Hi, I had personal experience switching from name brand to generic for Lexapro and it was horrible. It caused me a whole year of severe side effect after 1.5 yr of generic and I am still going through them now after 6 months switching back to name brand.

 

Since this is not lexapro, it may be different, but I would strongly recommend serious research and great caution. 


<p>2009 Mar.: lexapro 10mg for headache for 2 weeks.2009-2012: on and off 1/4 to 1/3 of 10mg2012 June--2013 Jan,: 1/4-1/3 of 10mg generic, bad jaw pain2013 Jan-Mar: 10 mg generic. severe jaw and head pain; Mar--Aug. started tapering (liquid ever since) from 10 to 5 (one step) then gradually down to 2.25 mg, first ever panic attack, severe head/jaw pain2013 Aug.: back to 2.75 mg; Nov: back to Brand Lex. 2.75mg -- 3mg, slight improvement with pain2014 June: stopped PPI, head pressure/numbness. up-dosed 4.5mg, severe reaction mental symptoms added on2014 Aug--2015 Aug: Micro taper down to 3.2mg, .025mg (<1%) cut holding 2-3 weeks.2015 Aug 15th, Accidental one dose of 4.2mg. worsening brain non-functional, swollen head, body, coma like, DR2016 Feb., started fast taper for the drug toxicity caused by the one dose of 4.2mg, dosing 10am through 11 pm everyday2/13--3.2mg, 3/15-- 2.9mg, 4/19-- 2.6mg, 6/26--2.2mg, 7/22 --1.9mg, 8/16--1.8mg,8/31--1.7m g, 9/13--1.6mg, 9/27--1.5mg, 10/8--1.4mg, 10/14--1.3mg, 11/1--1.2mg, 11/29--1.1mg, 12/12--1mg, 12/22--0.9mg2017: 1/7--0.8mg, 1/15--0.7mg, 1/17--0.6mg, 1/20--0.52, 1/21--0.4mg, 1/22--0.26, 1/23--0.2, sliding Down to 0.13mg by 2/13, then 0.07mg since 2/18, 0.06mg 2/20-3/17, 0.13mg 3/18

#30 Altostrata

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Posted 01 June 2014 - 09:20 AM

Yes, some people are sensitive to the differences between name brand and generic or even between different generic brands.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#31 btdt

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Posted 11 June 2014 - 03:21 AM

 

 

After reading more personal experiences on here - online - and becoming way more informed than before, I am disgusted, angry, fearful and generally at unrest watching psuedoscience hard at work  putting people into chemical straightjackets. 

I see you are new. 

This is something most of us have come to know sooner or later sadly all the emotions that come with the knowing hamper you healing... so if you can please try to step back from this just now and focus on your healing.  I know that is a tall order when in withdrawal but it is paramount that you heal that is more important than the truth right now... the truth will still be here when you well it has been here for years and is not going anywhere. 

I wish you peace 

peace is the state in which our bodies heal best....

peace.

 

Yes I am new to this board but not new to coming off vi tapering from SSRIs - unfortunately.

 

Unable to find work despite college degree and a return for a tech degree - I cannot afford brand - hence the need to switch to generic. I was just turned down for assistance due to skewed incorrect presumption about income.Had to draw the last of my IRA to survive - and it wasnt much - but with a astounding tax penalty that did more harm than good. 

 

I am not in withdrawal right now. Its not a return of my depressive state. It is pure unadulterated disgust with the lies I was sold and an RX now dependent on. The day I have to choose over eating food and dependence on an RX that never did anything to help and costs more than I spend on gas in a month is outrageous. 

 

There is no reason a generic should provide less quality though the discontinuation syndrome is very very real when I have taken it. I had anticipatory anxiety in the switch presuming the medicine potency was the same. I was told there is no difference by the pharmacist as well as a second MD I went to. Considering the unfavorable scenarios people go through in DS, the disparity is something that can cost someone their mental well being and possibly their life. 

 

Your not alone in your outrage! 

Effexor is expensive my drug coverage would not longer cover E when the generic came to market so I too paid out of pocket for it.  I was left with a few hundred dollars worth of meds when I quit not to mention a few other bottles of varying doses when I tried to go back on... all went in the garbage eventually. I know I should have taken them back to the drug store but I didn't.  I was in an angry mood and went through all the old pills in my possession and toss them all.  I thought I should keep the bottles so I have dates and did that ...but all the pills were bagged and tossed.  

I wonder how many millions of dollars in pills have ended up in the landfill. 

 

I am sure this does not make you any happier know people are throwing away drugs you need... it is stupid but laws mean people can't pass you off their old drugs or I would have easily... so would others I am sure. When I think how poor I am now and how I have not worked in years ...all the money I wasted on Effexor just pisses me off even more. 

 

Nope you not alone in your outrage I just can't keep the intensity year after year it waxes and wains.. bet is the same for other long timers.  

I wish you peace....


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivinganti...ng-myself-btdt/

There is a crack in everything ..That's how the light gets in :)


#32 NewMe

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Posted 08 July 2014 - 04:42 AM

 

 

 

After reading more personal experiences on here - online - and becoming way more informed than before, I am disgusted, angry, fearful and generally at unrest watching psuedoscience hard at work  putting people into chemical straightjackets. 

I see you are new. 

This is something most of us have come to know sooner or later sadly all the emotions that come with the knowing hamper you healing... so if you can please try to step back from this just now and focus on your healing.  I know that is a tall order when in withdrawal but it is paramount that you heal that is more important than the truth right now... the truth will still be here when you well it has been here for years and is not going anywhere. 

I wish you peace 

peace is the state in which our bodies heal best....

peace.

 

Yes I am new to this board but not new to coming off vi tapering from SSRIs - unfortunately.

 

Unable to find work despite college degree and a return for a tech degree - I cannot afford brand - hence the need to switch to generic. I was just turned down for assistance due to skewed incorrect presumption about income.Had to draw the last of my IRA to survive - and it wasnt much - but with a astounding tax penalty that did more harm than good. 

 

I am not in withdrawal right now. Its not a return of my depressive state. It is pure unadulterated disgust with the lies I was sold and an RX now dependent on. The day I have to choose over eating food and dependence on an RX that never did anything to help and costs more than I spend on gas in a month is outrageous. 

 

There is no reason a generic should provide less quality though the discontinuation syndrome is very very real when I have taken it. I had anticipatory anxiety in the switch presuming the medicine potency was the same. I was told there is no difference by the pharmacist as well as a second MD I went to. Considering the unfavorable scenarios people go through in DS, the disparity is something that can cost someone their mental well being and possibly their life. 

 

I don't care what they say is in the drug or how they are suppose to be the same the meltdown I had was not because I had anxiety about the drug switch as I did not notice it had been changed till after the damage was done.  

I no longer have a problem going against the norm or what they tell me as I know what I know and generics do not act the same inside my body as the brain name no matter what crap they are trying to sell... I am not buying.

 

Totally agree!


I'M A WEANER!  :D 
atavan PRN ,Paxil approx 20 yrs ago for major depression
Switched to Klonopin PRN through to current
Paxil wore out
Changed to Effexor 
Depakote added
enormous weight gain - flat affect - led to depression - dropped depakote
Dropped Effexor, changed to Paxil 
PDoc added mixed salts amphetamines for ADHD - took for 2 yrs - was ok at first but had to cut as symptoms too intense -  then the crash was too much. STOPPED
Vyvanse started in 2013 (APRIL) - more smooth than IR amphetamine tabs---Have not used vyvanse daily in full amt since May 2013 

Paxil CT withdrawal 10/2012  :wacko:  Klonopin CT WD

Switched Klonopin to Xanax prn  - too strong

WD CT from XANAX after taking for a while - it was awful but can be done if you hold on!

Back to Klonopin PRN - working very hard to avoid taking it at all. 

Effexor 37.5 started 02/2013, 75mg by 03/2013, 150mg by 05/2012 (approx)  :blush:

Effexor 150mg 3/10/2014 Microtaper -3beads  :unsure:

3/11/2014-4beads ,3/12/14 - 5, 3/13/14 -6, 3/15/14 - 7, 3/18 - 8, 3/22 - 10, 3/24 - 12, 4/6 - 13, 4/7 - 14, 4/11 - 16 - on 4/19 ran out of brand took generic. Bad move. Back on brand on 4/20 and updosed 2 beads. 5/1 - 15, 5/6 - 16, 5/9 -17, 55/10 -17, 5/15 -18, 5/21 -19, 5/24 -20, 6/3 - 21, 6/6 -23, 6/13 -24,6/19- 25, 6/21 -26, 6/25 -27

6/28 -28, 6/29 -30, 7/3 -34, 7/8 -35, 7/17 -36, 7/30 -41,7/31 -42, 8/2 -43, 8/3 -44, 8/5 -45, 8/14 -48, 8/26-50, 9/24 -53, 10/24 -55, 12/1 -57, (lost the tally sheet, thus taper info for some of it), 4/19-63, 4/26-64, 4/30-65 Switched to wt reduction - now @ -.068, 7/14 -.070, August 2015 -.074, between Sept & October 10 -.077, Nov. -.078(feeling great), -.090 as of 1/10/16, down to  -.101 since January 2016 (it is now 6/24/16), -.105 as of 8/13/16
 
 

Ladies, please don't underestimate the possibility of perimenopause. The symptoms can be similar to, may intensify & in some cases mimic protracted w/d from ssri's & benzo's. 

 


#33 NewMe

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Posted 08 July 2014 - 04:45 AM

 

 

 

After reading more personal experiences on here - online - and becoming way more informed than before, I am disgusted, angry, fearful and generally at unrest watching psuedoscience hard at work  putting people into chemical straightjackets. 

I see you are new. 

This is something most of us have come to know sooner or later sadly all the emotions that come with the knowing hamper you healing... so if you can please try to step back from this just now and focus on your healing.  I know that is a tall order when in withdrawal but it is paramount that you heal that is more important than the truth right now... the truth will still be here when you well it has been here for years and is not going anywhere. 

I wish you peace 

peace is the state in which our bodies heal best....

peace.

 

Yes I am new to this board but not new to coming off vi tapering from SSRIs - unfortunately.

 

Unable to find work despite college degree and a return for a tech degree - I cannot afford brand - hence the need to switch to generic. I was just turned down for assistance due to skewed incorrect presumption about income.Had to draw the last of my IRA to survive - and it wasnt much - but with a astounding tax penalty that did more harm than good. 

 

I am not in withdrawal right now. Its not a return of my depressive state. It is pure unadulterated disgust with the lies I was sold and an RX now dependent on. The day I have to choose over eating food and dependence on an RX that never did anything to help and costs more than I spend on gas in a month is outrageous. 

 

There is no reason a generic should provide less quality though the discontinuation syndrome is very very real when I have taken it. I had anticipatory anxiety in the switch presuming the medicine potency was the same. I was told there is no difference by the pharmacist as well as a second MD I went to. Considering the unfavorable scenarios people go through in DS, the disparity is something that can cost someone their mental well being and possibly their life. 

 

Your not alone in your outrage! 

Effexor is expensive my drug coverage would not longer cover E when the generic came to market so I too paid out of pocket for it.  I was left with a few hundred dollars worth of meds when I quit not to mention a few other bottles of varying doses when I tried to go back on... all went in the garbage eventually. I know I should have taken them back to the drug store but I didn't.  I was in an angry mood and went through all the old pills in my possession and toss them all.  I thought I should keep the bottles so I have dates and did that ...but all the pills were bagged and tossed.  

I wonder how many millions of dollars in pills have ended up in the landfill. 

 

I am sure this does not make you any happier know people are throwing away drugs you need... it is stupid but laws mean people can't pass you off their old drugs or I would have easily... so would others I am sure. When I think how poor I am now and how I have not worked in years ...all the money I wasted on Effexor just pisses me off even more. 

 

Nope you not alone in your outrage I just can't keep the intensity year after year it waxes and wains.. bet is the same for other long timers.  

I wish you peace....

 

OMG since the RX company refuses to pay this yr based on my tax return (which is a joke) the cost has about buried me in more debt.

 

I have been able to get a 6mos script and have Walgreen pharmacy fill 5 at a time. This way I won't end up with extras when I get off Satan's vitamin (Effexor). 

 

I appreciate your input. Thank you!


I'M A WEANER!  :D 
atavan PRN ,Paxil approx 20 yrs ago for major depression
Switched to Klonopin PRN through to current
Paxil wore out
Changed to Effexor 
Depakote added
enormous weight gain - flat affect - led to depression - dropped depakote
Dropped Effexor, changed to Paxil 
PDoc added mixed salts amphetamines for ADHD - took for 2 yrs - was ok at first but had to cut as symptoms too intense -  then the crash was too much. STOPPED
Vyvanse started in 2013 (APRIL) - more smooth than IR amphetamine tabs---Have not used vyvanse daily in full amt since May 2013 

Paxil CT withdrawal 10/2012  :wacko:  Klonopin CT WD

Switched Klonopin to Xanax prn  - too strong

WD CT from XANAX after taking for a while - it was awful but can be done if you hold on!

Back to Klonopin PRN - working very hard to avoid taking it at all. 

Effexor 37.5 started 02/2013, 75mg by 03/2013, 150mg by 05/2012 (approx)  :blush:

Effexor 150mg 3/10/2014 Microtaper -3beads  :unsure:

3/11/2014-4beads ,3/12/14 - 5, 3/13/14 -6, 3/15/14 - 7, 3/18 - 8, 3/22 - 10, 3/24 - 12, 4/6 - 13, 4/7 - 14, 4/11 - 16 - on 4/19 ran out of brand took generic. Bad move. Back on brand on 4/20 and updosed 2 beads. 5/1 - 15, 5/6 - 16, 5/9 -17, 55/10 -17, 5/15 -18, 5/21 -19, 5/24 -20, 6/3 - 21, 6/6 -23, 6/13 -24,6/19- 25, 6/21 -26, 6/25 -27

6/28 -28, 6/29 -30, 7/3 -34, 7/8 -35, 7/17 -36, 7/30 -41,7/31 -42, 8/2 -43, 8/3 -44, 8/5 -45, 8/14 -48, 8/26-50, 9/24 -53, 10/24 -55, 12/1 -57, (lost the tally sheet, thus taper info for some of it), 4/19-63, 4/26-64, 4/30-65 Switched to wt reduction - now @ -.068, 7/14 -.070, August 2015 -.074, between Sept & October 10 -.077, Nov. -.078(feeling great), -.090 as of 1/10/16, down to  -.101 since January 2016 (it is now 6/24/16), -.105 as of 8/13/16
 
 

Ladies, please don't underestimate the possibility of perimenopause. The symptoms can be similar to, may intensify & in some cases mimic protracted w/d from ssri's & benzo's. 

 


#34 NewMe

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Posted 08 July 2014 - 04:48 AM

I can't say I noticed any major difference between effexor XR and the generic until I started bead counting to try to taper off. There seemed to be a wide discrepancy with the size of the beads. The effexor beads seemed much bigger so if I was removing 100 beads from an effexor XR capsule then trying to remove 100 beads from a generic was never going to be the same. This led to some unpleasant side effects so now I insist on effexor only.

Harmonica

Thanks for your reply.

 

I have yet to get a scale so now I count beads that appear relatively uniform in size. I tend to pick the biggest ones. 

Your observations re gen and brand bead size is interesting. 

 

Thanks!


I'M A WEANER!  :D 
atavan PRN ,Paxil approx 20 yrs ago for major depression
Switched to Klonopin PRN through to current
Paxil wore out
Changed to Effexor 
Depakote added
enormous weight gain - flat affect - led to depression - dropped depakote
Dropped Effexor, changed to Paxil 
PDoc added mixed salts amphetamines for ADHD - took for 2 yrs - was ok at first but had to cut as symptoms too intense -  then the crash was too much. STOPPED
Vyvanse started in 2013 (APRIL) - more smooth than IR amphetamine tabs---Have not used vyvanse daily in full amt since May 2013 

Paxil CT withdrawal 10/2012  :wacko:  Klonopin CT WD

Switched Klonopin to Xanax prn  - too strong

WD CT from XANAX after taking for a while - it was awful but can be done if you hold on!

Back to Klonopin PRN - working very hard to avoid taking it at all. 

Effexor 37.5 started 02/2013, 75mg by 03/2013, 150mg by 05/2012 (approx)  :blush:

Effexor 150mg 3/10/2014 Microtaper -3beads  :unsure:

3/11/2014-4beads ,3/12/14 - 5, 3/13/14 -6, 3/15/14 - 7, 3/18 - 8, 3/22 - 10, 3/24 - 12, 4/6 - 13, 4/7 - 14, 4/11 - 16 - on 4/19 ran out of brand took generic. Bad move. Back on brand on 4/20 and updosed 2 beads. 5/1 - 15, 5/6 - 16, 5/9 -17, 55/10 -17, 5/15 -18, 5/21 -19, 5/24 -20, 6/3 - 21, 6/6 -23, 6/13 -24,6/19- 25, 6/21 -26, 6/25 -27

6/28 -28, 6/29 -30, 7/3 -34, 7/8 -35, 7/17 -36, 7/30 -41,7/31 -42, 8/2 -43, 8/3 -44, 8/5 -45, 8/14 -48, 8/26-50, 9/24 -53, 10/24 -55, 12/1 -57, (lost the tally sheet, thus taper info for some of it), 4/19-63, 4/26-64, 4/30-65 Switched to wt reduction - now @ -.068, 7/14 -.070, August 2015 -.074, between Sept & October 10 -.077, Nov. -.078(feeling great), -.090 as of 1/10/16, down to  -.101 since January 2016 (it is now 6/24/16), -.105 as of 8/13/16
 
 

Ladies, please don't underestimate the possibility of perimenopause. The symptoms can be similar to, may intensify & in some cases mimic protracted w/d from ssri's & benzo's. 

 


#35 Tabby

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Posted 26 July 2014 - 09:15 AM

My husband was placed on Effexor in 2006 for anxiety.   He’s been on generic version I guess since it became available—I’m not sure.  I don’t know if he had any side-effects going from the brand name to the generic, and it’s been too long for him to remember.  Due to “Effexor” causing him so many problems, he’s been weaning off it for the past year—he was on 150 mg and is now hanging out at the 37.5 mg pill level (we dropped him 5% each 3-4 weeks with a few longer stays whenever he felt increased “emotional” sensitivity, etc.).

 
Anyway, at his last refill, the pharmacy gave him the script broken into 2 bottles—one was his usual Teva generic and the other was Greenstone (which is “real” Effexor).  He’s about to start on the real Effexor, and I’m worried this might cause added problems in his withdrawal, side-effect process.  Any thoughts?  I just hate seeing him change “brands” during withdrawal from one, especially since I read something about someone going from generic back to brand and experiencing anxiety, etc.  Hubby cannot afford to get messed up with his new, highly visible job he just started on a few months ago.  
 
One thing I can do is fill our own capsules.  As I was researching here for info, I realized I had TONS of little beads (Teva brand) in a container from this weaning process.  I could get some empty capsules and fill them.  Then I need to know if the capsules themselves being different could cause problems (different dissolve rates).  Any ideas?
 
Thanks so much!


#36 LexAnger

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Posted 26 July 2014 - 02:11 PM

I can share some of my experience with shifting between the brand and generic although its for lexapro. I started with brand name on 2.5 mg for headache for years, when insurance changed it to generic, I had to increase the dose over the time to 10mg to help with the anxiety. Been on generic for 1 and half year, the killing jaw pain made me decided to tapering. I tapered from 10 to 2.5 in 3 months then could not going down further because the worsened jaw pain and panic attack. I stated there for another 4 months until I read the generic can cause jaw problems then I switched back to name brand. All kinds of withdral problems started in like 2 months after the shift so I had to increase the dose again to 3.7 then 4.5. One good thing is the jaw pain was gone after 7 months post shifting. In the last month I started tapering again from 4.5 to 3.8 now. I am scared to find the jaw pain came back yesterday. So in summary, the 2 shifts caused lots of problems and I suffered so much with various and severe symptoms also ended with much worse condition now. My feeling is shifting can trigger more damage and make your brain more sensitive. If the shift is for the consideration of cost, I would not suggest shift. Drug equivalence defined by industry or FDA is based on the potency of the active ingredients, but our problem now is Ssri induced problems not even the efficacy of the drug. Any tiny difference can mess up more of the brain then lead to unpredictable situation. Just my thoughts.
<p>2009 Mar.: lexapro 10mg for headache for 2 weeks.2009-2012: on and off 1/4 to 1/3 of 10mg2012 June--2013 Jan,: 1/4-1/3 of 10mg generic, bad jaw pain2013 Jan-Mar: 10 mg generic. severe jaw and head pain; Mar--Aug. started tapering (liquid ever since) from 10 to 5 (one step) then gradually down to 2.25 mg, first ever panic attack, severe head/jaw pain2013 Aug.: back to 2.75 mg; Nov: back to Brand Lex. 2.75mg -- 3mg, slight improvement with pain2014 June: stopped PPI, head pressure/numbness. up-dosed 4.5mg, severe reaction mental symptoms added on2014 Aug--2015 Aug: Micro taper down to 3.2mg, .025mg (<1%) cut holding 2-3 weeks.2015 Aug 15th, Accidental one dose of 4.2mg. worsening brain non-functional, swollen head, body, coma like, DR2016 Feb., started fast taper for the drug toxicity caused by the one dose of 4.2mg, dosing 10am through 11 pm everyday2/13--3.2mg, 3/15-- 2.9mg, 4/19-- 2.6mg, 6/26--2.2mg, 7/22 --1.9mg, 8/16--1.8mg,8/31--1.7m g, 9/13--1.6mg, 9/27--1.5mg, 10/8--1.4mg, 10/14--1.3mg, 11/1--1.2mg, 11/29--1.1mg, 12/12--1mg, 12/22--0.9mg2017: 1/7--0.8mg, 1/15--0.7mg, 1/17--0.6mg, 1/20--0.52, 1/21--0.4mg, 1/22--0.26, 1/23--0.2, sliding Down to 0.13mg by 2/13, then 0.07mg since 2/18, 0.06mg 2/20-3/17, 0.13mg 3/18