Jump to content

If you find useful information here, your gift would help keep this site going. Our staff is entirely volunteer.

Photo
* * * * * 3 votes

About reinstating and stabilizing to reduce withdrawal symptoms


  • Please log in to reply
136 replies to this topic

#73 Vonnegutjunky

Vonnegutjunky

    Silver star

  • Members
  • PipPipPip
  • 348 posts
  • LocationIndiana

Posted 22 August 2015 - 12:51 AM

So I am almost a week stabilized after 3 months of a double dose of reinstatment A

 

it was like a switch just flipped on Tuesday and bam I feel normal! I still have ringing in my ears, some side effects, a little anxiety but all of these things are before and after medication symptoms so I would not say they are wd related.

 

My doc really wanted me to switch meds- she said the Paxil was no longer working- I can't say I will be like this in an upward feeling of normalcy without anymore waves; I don't discount that I will probably have some, but it really is a huge difference; I think patience is the key with reinstatment (imo) as alto says our cns is unstablized and it needs stability.

 

So just wanted to post my experience here; and I hope my bad wd experience has prepared me for anything I might face when I begin to taper next year.


Edited by scallywag, 18 August 2016 - 12:25 PM.
inserted paragraph breaks

Started 20mg Paxil 2006 due to postpartum depression- went to 10 mg no problem in 2008 -
May 2014 10 mg alternating days 7.25 mg- July 2014 7.25 every day
September 2014 7.25 alternating days 5 mg- November 2014 5 mg day
January 1 2015 back up to 10 mg - April 23, 2015 15mg
May 13, 2015 20mg - (tabs weight 25.0mg) February 26th 7.5mg off 25mg tablet
Sept 4th 2015 2.5 off 25mg tablet | March 18th. 8mg off 25mg tablet
October 30th. 3.5 off 25mg tablet. | April 11th. 9mg off 25mg tablet
November15th 4mg off 25mg tablet. | May 5th. 10mg off 25mg tablet
December 12th 5mg off 25 mg tablet | May 19th. 11mg off 25mg tablet
January 4 6mg off 25mg tablet |. June 7. 11.5 mg off 25mg tablet
January 25th. 6.5 off 25 mg tablet. July 11. 12 mg off 25 mg tablet
February 15th. 7mg off 25mg tablet. August 7 back down----October 13 2016 - omega 3 4800 mg per day - October 13, 2016--- vitamin d 4000mg per day

#74 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,894 posts
  • LocationSan Francisco, CA

Posted 22 August 2015 - 10:44 AM

Thank you very much, VJ. It sounds like you've turned around in many ways. I hope you can educate your doctor about this.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#75 Colonial

Colonial

    Silver star

  • Members
  • PipPipPip
  • 377 posts
  • LocationNJ

Posted 04 October 2015 - 01:46 PM

Alto posted earlier in this thread:
 
 

 

Reinstatement is more likely to work done fairly soon after stopping a drug, while the nervous system is still somewhat shaped around the drug that's been removed. The window of opportunity is not definitely a month, and probably varies from individual to individual, but but reinstatement is best done sooner rather than later.This makes waiting to see if withdrawal symptoms will go away a difficult choice. If you wait, they may go away or you may miss your chance for effective reinstatement. After a while after discontinuation, the nervous system changes and may no longer accept reinstatement of the drug to repair the withdrawal reaction. It's like a series of dominoes gradually falling over time. Hypersensitivity can set in making reinstatement very difficult, as the nervous system will react in strange ways to the original drug and often other drugs as well. This is why when someone has been off the drug for more than a month, we suggest trying a very low dose. Hypersensitization is so common with withdrawal syndrome, trying a very low dose initially reduces the risk of a severe adverse reaction. And quite frequently, a very low dose will work to reduce withdrawal symptoms."

 
 
Colonial:  I have Never dropped below 10mgs of Paxil.  Which is well below therapeutic levels but, as I remember from the SERT curve study, is still enough to re-wire around 75% of your brain receptors.
 
So while I have been at this level almost 4 months do you think that since I never dropped below the 10mgs I may have better luck with "reinstatement" if the doctor wants me back up at higher doses?  I realize these studies are usually done on "virgin" brains, and after dropping down to 10mgs from being at 25 for almost 22 years, what my brain "looks" like may be different, but could there may be some "positive" news to having never dropped below that 10mg level for reinstatement purposes?


Edited by scallywag, 20 July 2016 - 07:45 PM.
moved quote to a quote box for clarity

 Starting ds 2 (12.5 CR'S) = 25 MG PAXIL CR 1/21/15: 1 Pill + 10mg liquid (2 weeks) 2/4: 1 Pill + 9mg Lq (3 weeks) 2/25: 1 Pill + 8 mg lq (1 week) 3/4: 1 Pill + 6 mg lq (2 weeks) 3/18 1 Pill + 4 mg lq (2 weeks) 4/1 1 Pill + 3 mg lq (2 weeks) 4/14 1 Pill + 2 mg lq (2 weeks) 4/29 1Pill + 1 mg lq (16 days) 5/15 1 12.5 mg Pill ONLY (9 days) 5/24 12 mgs liquid (8 days) 6/1 11mg lq (12 days) 6/13 10 mg.  12/3 Drop from 8mg to 7.6 (24 days to) 12/27/15 7.2mgs  8/4/16 6.8mgs,  11/1/16 6.4mgs, 2/5/17 6 mgs

 

Original Wellbutrin Dose: 6 months from 9/14 to 3/2015, 300 XL3/15: Half to 150 XL ( severe symptons started on day 12) 4/16: 125mg   for 20 days to: 5/6:   100mg  for  15 days to: 5/21    75mg  for  10 days to: 6/1:  56.25mg      13 days to: 6/13: 37.25mg    7 days to: 6/20  28.12mg   14 days to: 7/4  18.75mg, 7 days to: 7/11; RAISE BACK TO: 28.12 to 8/14: 18.75mg  20 days to :9/3/15 : 12.5mg, 8/4/16 9mg 1/9/17: 8.5mg 2/8/17 8mg, 3/9/17: 7.6

Xanax: 9/8-10/6: .5mg twice daily,  10/7-11/11: .375 twice daily, 11/12-12/17: .25 twice daily, 12/18-1/22: .125 twice daily. Stopped 1/23. One .25 dose 2/6,  one .625 dose 2/16 Xanax:  2/22/16  .125 mgs 4 times daily. 12 PM .125 mgs,  3/25/16: .125 3 times daily, 4/3: .125 3 times plus .0625 once daily, 6/1 .125 3x,  8/4: 0.3125 d, 11/15/16: .25 d, 3/5/17: 18.75MG

 

Daily medications:  Paxil, Wellbutrin, Percocet,  Synthroid, Xanax, 

http://www.drugs.com...,440-203,133-54

 


#76 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,894 posts
  • LocationSan Francisco, CA

Posted 04 October 2015 - 01:57 PM

If you've suffered withdrawal symptoms at any dosage, your nervous system may be sensitized to all psychiatric drugs.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#77 Colonial

Colonial

    Silver star

  • Members
  • PipPipPip
  • 377 posts
  • LocationNJ

Posted 04 October 2015 - 03:19 PM

So it's basically a crap shoot at this point...

So if I'm starting a new depressive episode, there may not be any hope of getting hold of it? 

I see why people kill themselves trying to get off these pills.

That's the amount of despair I feel at this point.


 Starting ds 2 (12.5 CR'S) = 25 MG PAXIL CR 1/21/15: 1 Pill + 10mg liquid (2 weeks) 2/4: 1 Pill + 9mg Lq (3 weeks) 2/25: 1 Pill + 8 mg lq (1 week) 3/4: 1 Pill + 6 mg lq (2 weeks) 3/18 1 Pill + 4 mg lq (2 weeks) 4/1 1 Pill + 3 mg lq (2 weeks) 4/14 1 Pill + 2 mg lq (2 weeks) 4/29 1Pill + 1 mg lq (16 days) 5/15 1 12.5 mg Pill ONLY (9 days) 5/24 12 mgs liquid (8 days) 6/1 11mg lq (12 days) 6/13 10 mg.  12/3 Drop from 8mg to 7.6 (24 days to) 12/27/15 7.2mgs  8/4/16 6.8mgs,  11/1/16 6.4mgs, 2/5/17 6 mgs

 

Original Wellbutrin Dose: 6 months from 9/14 to 3/2015, 300 XL3/15: Half to 150 XL ( severe symptons started on day 12) 4/16: 125mg   for 20 days to: 5/6:   100mg  for  15 days to: 5/21    75mg  for  10 days to: 6/1:  56.25mg      13 days to: 6/13: 37.25mg    7 days to: 6/20  28.12mg   14 days to: 7/4  18.75mg, 7 days to: 7/11; RAISE BACK TO: 28.12 to 8/14: 18.75mg  20 days to :9/3/15 : 12.5mg, 8/4/16 9mg 1/9/17: 8.5mg 2/8/17 8mg, 3/9/17: 7.6

Xanax: 9/8-10/6: .5mg twice daily,  10/7-11/11: .375 twice daily, 11/12-12/17: .25 twice daily, 12/18-1/22: .125 twice daily. Stopped 1/23. One .25 dose 2/6,  one .625 dose 2/16 Xanax:  2/22/16  .125 mgs 4 times daily. 12 PM .125 mgs,  3/25/16: .125 3 times daily, 4/3: .125 3 times plus .0625 once daily, 6/1 .125 3x,  8/4: 0.3125 d, 11/15/16: .25 d, 3/5/17: 18.75MG

 

Daily medications:  Paxil, Wellbutrin, Percocet,  Synthroid, Xanax, 

http://www.drugs.com...,440-203,133-54

 


#78 dreamspirit

dreamspirit

    Silver star

  • Members
  • PipPipPip
  • 149 posts
  • LocationMichigan

Posted 06 October 2015 - 03:36 PM

I totally understand when you say.. "I can see why people kill themselves"
I think alot of people think that way in withdrawl.. you feel there is no end in sight.. I know I've had thoughts of it.. it's so hard.. I would rather give birth then go through bad withdrawls..
But the withdrawls don't last forever.. I also tell myself. .. and in time, this too shall pass... hugs!!
1996/97-Started taking PaxilJan 2014-Started a taper of 1mg every 4-6 weeks-Got down to 30mg from 40mg.July 2015-Crash-Went back up to 40mg :-( Klonopin 1/4 tablet when needed which is rarely. Take as last resort.
-Panic/Anxiety DisorderPTSD,Occasional Agoraphobia

#79 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,894 posts
  • LocationSan Francisco, CA

Posted 06 October 2015 - 04:17 PM

I'm sorry it's so difficult. All we can do is keep on keeping on.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#80 Bking25

Bking25

    Getting started

  • Members
  • Pip
  • 1 posts
  • LocationAsheville

Posted 29 October 2015 - 05:31 PM

hello I haven't posted on this site before but i used it regularly in my withdraw.  I was on medication since i was 18 years old and stopped when i was 31.  My last medication was lexapro, I slowly tapered myself down for an entire year.  The last day was hell i suffered from unrelenting dp/dr suicidal thoughts inability to put sentences together i suffered med free for 16 months, I couldn't read or listen to music i couldn't even go outside without suffering major dp.  I was afraid to drive and had thoughts that would enter my mind out of nowhere to go drive off a bridge.  I would see evil faces on people out of the corner of my eye that really scared me.  needless to say i was a mess.  I worried my family and nearly drove my very loving girlfriend into a break up.  I went to every doctor and had every test known to man.

I finally landed my dream job and was scared to death to take it.  my anxiety dp d/r was so great i decided to go to the doctor. and was prescribed 25mg zoloft i read so many post saying it would never work and it would just make things worse. i was very anti medication and i believed i was a lost cause i believed what i read on here and made it true in my mind that i was hopeless.  thankfully Thats not my experience. I have been on zoloft now for two months the first two weeks were classic when starting an ssri increased anxiety etc.  I am currently a different person I am a firefighter like i always dreamed of and worked so hard pre withdrawal. my dp is 99% gone and my depression is about 70 % better. I can concentrate as well as listen to music. I'm not 100% but reinstatement WORKED for me it changed my life.  I am ok with being on medication again I have my life back. my girlfriend is very happy and it still brings tears to my parents eyes when i call and say "im doing good mom"  because for so long that was not the case  My mother and father have their son back and my brothers have their big brother back! i know this is an anti medication web site i just felt compelled to reach out to those on the brink of suicide I was there i had no quality of life and yes if taking medication pulls me back from the ledge and gives me a quality of life that i didn't have before then so be it .good luck to all and find your own path. Don't give up      THERE IS HOPE!



#81 servadei

servadei

    Silver star

  • Members
  • PipPipPip
  • 293 posts
  • LocationCroatia

Posted 30 October 2015 - 08:51 AM

I think I will have to start a new ad...I have no life. It's unbearable. BKing I feel the same. All the same symptoms. Constant suicidal thoughts all day.

Jan2014-July2015 Escitalon (escitalopram) 10mg

10/10/2015- 4 months in withdrawal, coping very hard, praying for a window


#82 Junglechicken

Junglechicken

    Gold star

  • Members
  • PipPipPipPip
  • 1,237 posts
  • LocationReading, UK and also Southwest, UK

Posted 03 November 2015 - 08:15 AM

I stopped taking Cipralex completely mid-September 2015 after a 3 month taper from 10mg.

 

Since then I have experienced heightened anxiety and depression (had one panic attack so far), suicidal thoughts, hand tremors, nausea, non-stop high pitched tinnitus, sinus headaches/"sub-clinical" migraines, random headaches, crying spells, muscle and joint pain (injured my lower back twice now) and am having physio once a week.

 

All the doctors I have spoken to suggest I should re-instate. The last doctor I saw said I have a serious "mental" illness/disease and should talk to my doctor asap and be back on Cipralex.

 

This is the most depressing time of my life.  I lost my job in June of this year and have been for the most part house-bound except for going out and exercising.  My social interactions are predominately to see health care practitioners of what sort of another.

 

Feels like I am in hell.....


<p>Feb 2014 -Cipralex/Escitalopram 10mg daily June 2015 - Started taper, 5mg every other day July 2015 - 5mg every 2 days August 2015 - 5mg every 3 days September 2015 - 5mg every 4 days Sept 14th - Completed tapering, but at 7 weeks "drug free" I suffered serious WD symptoms as a consequence of "incorrect" tapering. Nov 25 2015 - Re-instated Cipralex @ 2.5mg daily. WD symptoms disappeared over a few days. Have been on this dose ever since and am experiencing "windows" and "waves". Nov 15th 2016 Re-started Therapy Jan 19th 2017 Started CBT. Jan 2017 Homeopathic Treatment starts 4th Jan 2017. Mar 2017 Naturopathic Treatment starts - anti-Candida diet starts as diagnosis of Candida Related Complex (CRC). 24 March 2017 DETOX started for anti-Candida to help "re-set" my gut. April 2017 Gut Cleanse - 6 weeks.Plan to re-start taper (liquid Cipralex/Escitalopram)

#83 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,894 posts
  • LocationSan Francisco, CA

Posted 05 November 2015 - 08:56 PM

Reinstating is the only way medicine knows to reduce withdrawal syndrome, you've gotten decent advice there. Quite often, we see it works.

 

Needing to reinstate does not mean you have a "mental illness" -- that doctor was wrong. It means you tapered too fast and you need to taper slower.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#84 starcontrol2

starcontrol2

    Member

  • Members
  • PipPip
  • 89 posts
  • LocationMaryland

Posted 08 November 2015 - 07:04 PM

Hopefully my experience will help someone.
I tapered from 5mg of Lexapro too fast. Like most was just following what dr was saying. I cut to 2.5 then to 1.25. I never made it to zero. I made it to 0.625mg. I was in severe withdrawal.
Reinstated to 5mg while never reaching 0, also on doctors advice. It made everything worse and totally destroyed my sleep. I waited for 2 months at 5 but couldn't stabilize.

10/2012 - Lexapro 10mg

2013/2014 - Started experiencing visual disturbances, like visual processing was slow, feeling drunk all the time

9/2014 - Lexapro 5mg, didn't notice any withdrawal, drunk feeling went away

2015 - Drunk feeling came back

5/2015 - Lexapro 2.5mg - 1.25mg - insomnia started

6/2015 - Lexapro 0.625mg

7/2015 - Severe symptoms started, in desperation on advice of pdoc restarted 5mg Lexapro - total disaster

8/2015 - Lexapro 5mg, disoriented, sleepless zombie

9/2015 - Very reluctantly started transitioning to Zoloft

as of 10/10/2105 - no lexapro, 37.5mg Zoloft

12/14/2015 - 35mg zoloft, 1/16/2016 - 34mg


#85 reachingforthestars

reachingforthestars

    Silver star

  • Members
  • PipPipPip
  • 204 posts
  • LocationEurope

Posted 12 November 2015 - 12:05 AM

startcontrol, i have similar experience.... a couple of days ago i updosed from 4mg to 5mg and it triggered new symptoms to me. :( Before my symptoms were so much easier compared to this all i had was tiredness and muscle weakness so that i was housebound, and nausea( on and off),  but now i have also terrible insomnia, constant restlessness,  and my eyes are sore. If i could i would undo that updosing...

 

i would really like to hear how long has it took for those of you who has updosed with bad reaction to stabilize? please i need some hope... 


Citalopram 40mg from 2003-2015

Jan 2015 started tapering first dropped to 35mgFeb 30mg, March 25mgApril 20mg, May 17,5mg, June 15mgJuly 12,5mg, Aug 12,5mg,

Sep 0mg for 5 days because of stomac flu and after I raised to 7,5mg. All the symptoms of acute WD shaking, diarrhea, vomiting, barely could walk ect. Still didn't realize that it wasn't only stomac flu but I was also going through WD.

Oct 2,5mg and crashed again badly and quickly raised to 4mg. It was then when I knew my symptoms were due to WD.

Then in November after a month holding on 4mg raised to 5mg due to muscle weakness and had a VERY BAD reaction to reinstatement: akathisia(lasted for one or two weeks), insomnia, anhedonia... Drop quicly back to 4mg, Dec 3mg

Jan 2016 2,6mg( in the middle of Jan after I had been on 2,6mg for a week I tried to updose to 2,8mg and immediately had bad reaction to it: akathisia for a day, andehonia got worse. The next day dropped back to 2,6mg), Feb 2,4mg( a new symptom PGAD lasted 24/7 for 2 months after that on and off), March 2,4mg, April 2,3mg, May 2,2mg, June 2,1mg, July 2,0mg( Pgad almost nonexisting, sleeping pretty good, still some anhedonia but there has been a lot of gradual progress), Aug 1,97mg-1,89mg, Sep 1,88mg-1,49mg, Oct 1,48mg- 1,70mg,

Nov 0,65mg- current dose 0,5mg

 


#86 Vonnegutjunky

Vonnegutjunky

    Silver star

  • Members
  • PipPipPip
  • 348 posts
  • LocationIndiana

Posted 20 November 2015 - 04:11 AM

I also updosed during a too fast taper and everything got really really bad! I waited for 5 months to stabilize before I started reducing again; only now after 2 months of reducing do I have Windows where I feel normal! They come ever 9-12 days but during those windows I feel so much better, more hopeful

My advice, if your symptoms got worse after an updose, don't wait 5 months; start shaving your pill; I was in pure and utter despair;

My updose made things so much worse
Started 20mg Paxil 2006 due to postpartum depression- went to 10 mg no problem in 2008 -
May 2014 10 mg alternating days 7.25 mg- July 2014 7.25 every day
September 2014 7.25 alternating days 5 mg- November 2014 5 mg day
January 1 2015 back up to 10 mg - April 23, 2015 15mg
May 13, 2015 20mg - (tabs weight 25.0mg) February 26th 7.5mg off 25mg tablet
Sept 4th 2015 2.5 off 25mg tablet | March 18th. 8mg off 25mg tablet
October 30th. 3.5 off 25mg tablet. | April 11th. 9mg off 25mg tablet
November15th 4mg off 25mg tablet. | May 5th. 10mg off 25mg tablet
December 12th 5mg off 25 mg tablet | May 19th. 11mg off 25mg tablet
January 4 6mg off 25mg tablet |. June 7. 11.5 mg off 25mg tablet
January 25th. 6.5 off 25 mg tablet. July 11. 12 mg off 25 mg tablet
February 15th. 7mg off 25mg tablet. August 7 back down----October 13 2016 - omega 3 4800 mg per day - October 13, 2016--- vitamin d 4000mg per day

#87 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,894 posts
  • LocationSan Francisco, CA

Posted 20 November 2015 - 09:15 AM

VJ, didn't you take a big dose instead of the low dose we suggested?


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#88 Mort81

Mort81

    Silver star

  • Members
  • PipPipPip
  • 788 posts
  • LocationCanada

Posted 02 December 2015 - 09:00 AM

When I am in a heavy wave I still think of reinstating. 15 months off and im not functional yet, but the thought of it getting worse always sways me away from trying it out.
Was on 30mg (Lexapro) for 7-8yrs20mg for 3 months (This was my choice my Doc wanted me to drop much faster)15 mg 2week10mg 2 weeks 5 mg 1 week0 since August 24th Clonazapam. Currently 0.10mg daily. PPI Dexlant 20-30mg for last 29 months currently at 30mg

#89 Vonnegutjunky

Vonnegutjunky

    Silver star

  • Members
  • PipPipPip
  • 348 posts
  • LocationIndiana

Posted 05 December 2015 - 06:15 PM

Yes alto I did- I jumped up to 20- I did what my doc told me to do- mistake - huge mistake
Started 20mg Paxil 2006 due to postpartum depression- went to 10 mg no problem in 2008 -
May 2014 10 mg alternating days 7.25 mg- July 2014 7.25 every day
September 2014 7.25 alternating days 5 mg- November 2014 5 mg day
January 1 2015 back up to 10 mg - April 23, 2015 15mg
May 13, 2015 20mg - (tabs weight 25.0mg) February 26th 7.5mg off 25mg tablet
Sept 4th 2015 2.5 off 25mg tablet | March 18th. 8mg off 25mg tablet
October 30th. 3.5 off 25mg tablet. | April 11th. 9mg off 25mg tablet
November15th 4mg off 25mg tablet. | May 5th. 10mg off 25mg tablet
December 12th 5mg off 25 mg tablet | May 19th. 11mg off 25mg tablet
January 4 6mg off 25mg tablet |. June 7. 11.5 mg off 25mg tablet
January 25th. 6.5 off 25 mg tablet. July 11. 12 mg off 25 mg tablet
February 15th. 7mg off 25mg tablet. August 7 back down----October 13 2016 - omega 3 4800 mg per day - October 13, 2016--- vitamin d 4000mg per day

#90 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,894 posts
  • LocationSan Francisco, CA

Posted 05 December 2015 - 07:56 PM

I understand you were following your doctor's orders. The reason we suggest a very low dose as reinstatement is to avoid adverse effects from a powerful dose, which can delay stabilization or make someone worse.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#91 Christian

Christian

    Silver star

  • Members
  • PipPipPip
  • 509 posts
  • LocationChicago

Posted 06 January 2016 - 12:24 PM

I'm on day 6 of Lexapro reinstatement and actually felt OK for a couple hours minus the exhaustion from insomnia. I hope to build on that amount of time tomorrow.
Lexapro: started in 2002 at 10 mgs.
Ambien: started as a as needed sleep aid in 2010.
Quit Lexapro cold turkey in June 20015 due to contributing to low sodium issues.
Restarted Lexapro in late November for a week (only 5 mgs) but quit due to dizziness side effects. Side effects worsened for 3 weeks until
12/24/15: Protracted WD hit, experienced extreme anxiety, insomnia lack of full concentration and social challenges.
Reinstated Lexapro on 1/1/16 at 5 mgs. Increased per Dr to 7.5 MG. Tapered off Lexapro in March 2016.
Started 50MG of Seroquel in late January 2016 for bedtime to help in eliminate Ambien. Tapered off both Seroquel and Ambien in March 2016.
2/14/16: Prescribed both Remeron (15 MG) and Temazapam (15 MG) for sleep. Also use Klonopin and Ambien again in place of Temazapam to avoid addiction. However I did take Temazapam 60 straight days
6/15/16: Stopped use of all benzo's and now use Belsomra 1-2 times a week. Still on 15 MG of Remeron
10/11/16: Off all psych medications

After kindling, trying to regain my strength suffering from severe mental and physical fatigue.

#92 Mort81

Mort81

    Silver star

  • Members
  • PipPipPip
  • 788 posts
  • LocationCanada

Posted 14 January 2016 - 09:57 PM

Hey guys I always re-read this thread during a wave. And I am in a bad one. Bedridden for 2 days and counting due to a myriad of intense symptoms. I usually read the forum and talk myself out of reinstating. My gut says no but I dont know foresure. I am 17 months off and although Ive seen some improvements, I am not functional yet. Could a 1mg reinstatement make me much worse? I guess in tough times I need to know that by not reinstating im doing the best thing for my recovery or am I making a mistake by not trying reinstatement? Any advice is appreciated. Thanks

Mort
Was on 30mg (Lexapro) for 7-8yrs20mg for 3 months (This was my choice my Doc wanted me to drop much faster)15 mg 2week10mg 2 weeks 5 mg 1 week0 since August 24th Clonazapam. Currently 0.10mg daily. PPI Dexlant 20-30mg for last 29 months currently at 30mg

#93 reachingforthestars

reachingforthestars

    Silver star

  • Members
  • PipPipPip
  • 204 posts
  • LocationEurope

Posted 14 January 2016 - 11:21 PM

Mort, For me updosining made me sooo much worse and it took at least a month to stabilize somewhat. I only updosed from 4mg to 5mg and felt like my brain was exploding...  I developed new symptoms like andehonia and insomnia and akathisia. It was really traumatising. I think that in your case when you have been off meds for so long reinstatement would be really like russian roulette.


Citalopram 40mg from 2003-2015

Jan 2015 started tapering first dropped to 35mgFeb 30mg, March 25mgApril 20mg, May 17,5mg, June 15mgJuly 12,5mg, Aug 12,5mg,

Sep 0mg for 5 days because of stomac flu and after I raised to 7,5mg. All the symptoms of acute WD shaking, diarrhea, vomiting, barely could walk ect. Still didn't realize that it wasn't only stomac flu but I was also going through WD.

Oct 2,5mg and crashed again badly and quickly raised to 4mg. It was then when I knew my symptoms were due to WD.

Then in November after a month holding on 4mg raised to 5mg due to muscle weakness and had a VERY BAD reaction to reinstatement: akathisia(lasted for one or two weeks), insomnia, anhedonia... Drop quicly back to 4mg, Dec 3mg

Jan 2016 2,6mg( in the middle of Jan after I had been on 2,6mg for a week I tried to updose to 2,8mg and immediately had bad reaction to it: akathisia for a day, andehonia got worse. The next day dropped back to 2,6mg), Feb 2,4mg( a new symptom PGAD lasted 24/7 for 2 months after that on and off), March 2,4mg, April 2,3mg, May 2,2mg, June 2,1mg, July 2,0mg( Pgad almost nonexisting, sleeping pretty good, still some anhedonia but there has been a lot of gradual progress), Aug 1,97mg-1,89mg, Sep 1,88mg-1,49mg, Oct 1,48mg- 1,70mg,

Nov 0,65mg- current dose 0,5mg

 


#94 Mort81

Mort81

    Silver star

  • Members
  • PipPipPip
  • 788 posts
  • LocationCanada

Posted 15 January 2016 - 04:46 PM

Reaching thanks for sharing your experience. I think other than my really bad waves. Which when Im in them feels like they will never end,I am able to deal with my limitations and symptoms. Not easily but I am generally hopeful that It will continue to get better. But I don't wanna think about what if a reinstatement made things worse. That idea is terrifying
Was on 30mg (Lexapro) for 7-8yrs20mg for 3 months (This was my choice my Doc wanted me to drop much faster)15 mg 2week10mg 2 weeks 5 mg 1 week0 since August 24th Clonazapam. Currently 0.10mg daily. PPI Dexlant 20-30mg for last 29 months currently at 30mg

#95 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,894 posts
  • LocationSan Francisco, CA

Posted 16 January 2016 - 02:31 PM

moved posts to mort81's Intro topic as they were getting very off-topic here.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#96 VinceC

VinceC

    Member

  • Members
  • PipPip
  • 25 posts
  • LocationCanada

Posted 16 May 2016 - 10:58 AM

 

How long should you give reinstatement?

  • It takes at least 4 days for your body to fully register the addition of a neuroactive drug. Unless you have an immediate bad reaction, observe your symptom pattern for about a week to see if the reinstatement is helping. If you have an immediate bad reaction, reduce or stop taking the drug.

 

Hi Altostrata,

 

 Can you explain this a little further? how come the body doesn't notice the drug until 4 day?


Venlafaxine 150mg (Oct, 20 2008)

Venlafaxine 75mg (Aug, 2010)

Escitalopram 10mg (June,04,2014)

Sertraline 100mg (Dec, 2014 - March 22, 2016)

 

I have been on SSRI's a total of 8 years.

 

By doctors orders tapered off Sertraline from early Oct to March 22 2016. Drug free until May 14th, reinstated at 6.25mg due to completely debilitating withdrawal symptoms.

Have not stabilized since, and still suffering immensely.  

 


#97 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,894 posts
  • LocationSan Francisco, CA

Posted 16 May 2016 - 02:21 PM

I believe brassmonkey already explained that it takes about 4 days for a drug to reach steady-state in your bloodstream due to overlapping half-lives.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#98 VinceC

VinceC

    Member

  • Members
  • PipPip
  • 25 posts
  • LocationCanada

Posted 16 May 2016 - 03:11 PM

I believe brassmonkey already explained that it takes about 4 days for a drug to reach steady-state in your bloodstream due to overlapping half-lives.

 

Oh steady state. I understand.

 

I apologize, I thought you meant the brain does't make any changes until its been in the body for 4 days.


Venlafaxine 150mg (Oct, 20 2008)

Venlafaxine 75mg (Aug, 2010)

Escitalopram 10mg (June,04,2014)

Sertraline 100mg (Dec, 2014 - March 22, 2016)

 

I have been on SSRI's a total of 8 years.

 

By doctors orders tapered off Sertraline from early Oct to March 22 2016. Drug free until May 14th, reinstated at 6.25mg due to completely debilitating withdrawal symptoms.

Have not stabilized since, and still suffering immensely.  

 


#99 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,894 posts
  • LocationSan Francisco, CA

Posted 16 May 2016 - 03:48 PM

Prior to about 4 days, there are variations of the drug level in your bloodstream, your body does not get the full dose consistently 24 hours a day until around the 4th day. You may still feel effects of the drug, though.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#100 Help777

Help777

    Silver star

  • Members
  • PipPipPip
  • 190 posts
  • LocationCanada

Posted 17 May 2016 - 03:37 AM

Did you improve before you had to reinstate? Just wondering how long people gave it before reinstating?
Thank you..
<p>2000 effexor xr 112.5mgTried weaning twice over last few years, gave up after emotional turmoilNoticed mood instability over last few years and went to see pdoc.Pdoc diagnosed bpII and suggested I start lithium and 'wean effexor.Sept 2015 added lithium 300mg.Sept 2015 started to wean effexor.Oct 2015 weaned effexor xr to 75 mg. experienced crying bouts and pdoc suggested prozac bridge to assist taper.Oct 2015 added prozac 20 mg to help bridge; continuing with 75mg effexor, 300 lithiumNov 2015 effexor xr down to 37.5mg, continuing prozac 20 mg and lithium 300 mg.Dec 2015 Started counting effexor beads as dose is now smaller than the 37.5mg capsule - at 86 beads, cont prozac 20 mg, lithium 300 mgJan 2016 effexor 66 beads, which is about 20mg. Continuing with prozac 20mg and lithium 300mg. Also, Omega 3Feb 2016 56 beads of effexor xr. Prozac 20 mg. lithium 300mg, also Omega
3March 2016 Effexor-36 beads. Prozac-10 mg. Lithium 300 mg, also Omega 3 and probiotics, gf, no sugar, high fat, protein diet.
April 2016 Effexor 26 beads, Prozac 10 mg, Lithium 300 mg. also, Omega 3 and probiotics. gf, no sugar, high fat, protein diet.<p>
May 12th took last bead of effexor. Will begin to taper prozac 5mg at a very slow rate. Continuing with 300mg Lithium for now.
May 31st took last of prozac. Continuing Lithium 300 mg, estrogen patch 150, magnesium.
June 14th reinstated 1mg Prozac due to intolerable emotional distress. Cont with lithium 300mg, 150 magnesium, re added omega 3, cont estrogen patch. June 15-july 5th had marked improvement of emotional wd symptoms, likely due to the reinstatement. Wave came crashing in around July 5th and intense emotional symptoms returned.
July 15 decreased 50 mg of lithium to see if it improved low heart rate.
July 19th - increased prozac to 1.5mg.
July 22 marked improvement of emotional symptoms...again, likely due to increase of prozac. However sudden agitation developed so decreased back down to 1.25mg prozac. Realizing increasing dose is dangerous because of these adverse effects and also seeing that wave is inevitable regardless of reinstatement.
Continuing 250 lithium, 1.25mg prozac, estrogen.
Oct 31st - continued 250 lithium, 1 mg prozac, estrogen patch. Thinking about retrying omega 3 and magnesium but they made symptoms worse when i tried a few months ago.

#101 Weasel

Weasel

    Member

  • Members
  • PipPip
  • 80 posts
  • LocationColumbus

Posted 17 May 2016 - 03:06 PM

Has anyone had a long window after reinstating and then have a wave come?
Zoloft 6mg gabapentin 600 mg lamictal 25 mg

#102 woof

woof

    Silver star

  • Members
  • PipPipPip
  • 243 posts
  • LocationColorado Springs

Posted 21 July 2016 - 09:56 AM

Should one begin to taper after reinstatement, if their symptoms have not completely abated?


2004-2015 Cymbalta 20mg/d No problems at all with Cymbalta, I just wanted to get off of all meds.  Nov, 25 2015 CT 20mg/d Cymbalta (194 beads)   

Jan 2016 Reinstated 20mg/d Cymbalta (194 beads) 5 weeks after CT

Jan-April 2016 Held Cymbalta 20mg/d for 4 months. All wd sx's gone, except: 4/10 AM anxiety 9-1:30 only after 7:30 AM Cymbalta, 2/10 tinnitus & 2-4 AM waking then back to sleep. 

April 21 2016 Prematurely CUT -Cymbalta 20-18mg (194-19 = 175 beads) - AM anxiety resolved :)  May 21, 2016 cut to (158 beads) 16mg-stable,

July 04, 2016 cut to (143 beads) 14.5mg and had 10/10 wd sx's  Anxiety, Anhedonia, Anorexia, Fear, dysphoria, could not go back to sleep after 1:30 AM wake-up.

Nov 29th 2016 UPDOSED (41 beads) Cymbalta to 20mg (194 bead) all sxs except tinnitus virtually gone. 

I plan to stay on 20mg/d Cymbalta.  Nothing but improvement since updosing.  Stable with no anxiety and greatly improved sleep as of March 8th 2017

FEB 2016 STARTED Valium 25mg/d for the CT Cymbalta wd sxs.   August 2016 Increased Valium to 28mg/qhs, due wd sx's from July 4, 2016 Cymbalta cut.

Jan 1, 2017  Cut Valium 28mg qhs 28mg-3mg=25mg.    March 11,2017 25mg-2mg=23mg   Plan to decrease Valium 10% per 4 weeks as tolerated.  Fish oil

http://survivinganti...key-withdrawal/  Benzo Posts http://survivinganti...ta-wd-symptoms/

 

 


#103 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,894 posts
  • LocationSan Francisco, CA

Posted 21 July 2016 - 10:39 AM

woof, because the answer is "that depends...." that's the kind of question that belongs in your Intro thread, it would lead to a discussion about your own situation that would go off-topic here.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#104 woof

woof

    Silver star

  • Members
  • PipPipPip
  • 243 posts
  • LocationColorado Springs

Posted 21 July 2016 - 11:40 AM

Ok, thanks Alto. :)


2004-2015 Cymbalta 20mg/d No problems at all with Cymbalta, I just wanted to get off of all meds.  Nov, 25 2015 CT 20mg/d Cymbalta (194 beads)   

Jan 2016 Reinstated 20mg/d Cymbalta (194 beads) 5 weeks after CT

Jan-April 2016 Held Cymbalta 20mg/d for 4 months. All wd sx's gone, except: 4/10 AM anxiety 9-1:30 only after 7:30 AM Cymbalta, 2/10 tinnitus & 2-4 AM waking then back to sleep. 

April 21 2016 Prematurely CUT -Cymbalta 20-18mg (194-19 = 175 beads) - AM anxiety resolved :)  May 21, 2016 cut to (158 beads) 16mg-stable,

July 04, 2016 cut to (143 beads) 14.5mg and had 10/10 wd sx's  Anxiety, Anhedonia, Anorexia, Fear, dysphoria, could not go back to sleep after 1:30 AM wake-up.

Nov 29th 2016 UPDOSED (41 beads) Cymbalta to 20mg (194 bead) all sxs except tinnitus virtually gone. 

I plan to stay on 20mg/d Cymbalta.  Nothing but improvement since updosing.  Stable with no anxiety and greatly improved sleep as of March 8th 2017

FEB 2016 STARTED Valium 25mg/d for the CT Cymbalta wd sxs.   August 2016 Increased Valium to 28mg/qhs, due wd sx's from July 4, 2016 Cymbalta cut.

Jan 1, 2017  Cut Valium 28mg qhs 28mg-3mg=25mg.    March 11,2017 25mg-2mg=23mg   Plan to decrease Valium 10% per 4 weeks as tolerated.  Fish oil

http://survivinganti...key-withdrawal/  Benzo Posts http://survivinganti...ta-wd-symptoms/

 

 


#105 Machinehead

Machinehead

    Member

  • Members
  • PipPip
  • 40 posts
  • LocationSweden

Posted 22 July 2016 - 02:02 AM

How much should I wait before increasing the dose of reinstatement? It's been a week for me and things are still pretty dark.(2.5mg Lexapro).
Benzo (Iktorivil; 2mg): 1999-2012 Last dose: 0,1mg January 2012
SSRI (Escitalopram; 10mg): 2002-2016 Stopped 2,5mg February 2016 - Back to 5mg in July 2016.

"...You ask, what is our aim? I can answer in one word: Victory. Victory at all costs—Victory in spite of all terror—Victory, however long and hard the road may be, for without victory there is no survival." - Churchill

#106 Altostrata

Altostrata

    Administrator

  • Administrators
  • PipPipPipPipPipPip
  • 23,894 posts
  • LocationSan Francisco, CA

Posted 22 July 2016 - 02:54 PM

Machinehead, that is the kind of "that depends..." question that belongs in your Intro topic. In fact, there's a discussion going on there right now.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#107 reachingforthestars

reachingforthestars

    Silver star

  • Members
  • PipPipPip
  • 204 posts
  • LocationEurope

Posted 07 September 2016 - 10:05 PM

Alto, have you gotten your emotions back after your reinstatement? You wrote in some thread that you were on Paxil first few years and then you were off for an year and then you started Paxil again and on the second time on Paxil it blunted your emotions. I wanted to ask this bc you have been off Paxil after you CT'ed for so long and bc so so many experience anhedonia after reinstatement. 


Citalopram 40mg from 2003-2015

Jan 2015 started tapering first dropped to 35mgFeb 30mg, March 25mgApril 20mg, May 17,5mg, June 15mgJuly 12,5mg, Aug 12,5mg,

Sep 0mg for 5 days because of stomac flu and after I raised to 7,5mg. All the symptoms of acute WD shaking, diarrhea, vomiting, barely could walk ect. Still didn't realize that it wasn't only stomac flu but I was also going through WD.

Oct 2,5mg and crashed again badly and quickly raised to 4mg. It was then when I knew my symptoms were due to WD.

Then in November after a month holding on 4mg raised to 5mg due to muscle weakness and had a VERY BAD reaction to reinstatement: akathisia(lasted for one or two weeks), insomnia, anhedonia... Drop quicly back to 4mg, Dec 3mg

Jan 2016 2,6mg( in the middle of Jan after I had been on 2,6mg for a week I tried to updose to 2,8mg and immediately had bad reaction to it: akathisia for a day, andehonia got worse. The next day dropped back to 2,6mg), Feb 2,4mg( a new symptom PGAD lasted 24/7 for 2 months after that on and off), March 2,4mg, April 2,3mg, May 2,2mg, June 2,1mg, July 2,0mg( Pgad almost nonexisting, sleeping pretty good, still some anhedonia but there has been a lot of gradual progress), Aug 1,97mg-1,89mg, Sep 1,88mg-1,49mg, Oct 1,48mg- 1,70mg,

Nov 0,65mg- current dose 0,5mg

 


#108 Henosis

Henosis

    Member

  • Members
  • PipPip
  • 80 posts
  • LocationSpokane, WA

Posted 07 September 2016 - 10:21 PM

Just throwing in my experience...

- re-instated Paxil ~15mg approx FIVE months after severe withdrawal started (itself taking 6 weeks after my last pill). Sounds like I was lucky considering this is on the far end of successful reinstatement delays.

- reinstatement quickly cleared up the withdrawal insanity (panic attacks, cognitive dysfunction/memory loss, de-realization, worst OCD of my life)

- unfortunately, reinstatement also brought a *fierce* anhedonia, apathy, and loss of motivation - The likes of which I hadn't experienced in ten years of 60mg+ Paxil. This hasn't gone away yet, I'm on 8mg and still tapering slowly. In some ways, this is much worse than withdrawal since I could still enjoy music, sex, sunshine, socializing etc during withdrawal.

- muscle pain, digestive issues, general spaciness still lingered after reinstatement.

Medication before problems: Took Paxil 60-100mg from 2003 to 2014 for OCD.
1) Last pill taken November 2014, horrendous withdrawal started six weeks later.

2) Re-instated successfully @ 20mg May 2015, but accompanied by severe anhedonia, loss of emotion, apathy, and fatigue

3) Switched to Prozac, Viibyrd, Zoloft, Nefazadone, Cymbalta, Nardil in attempt at abating WD symptoms while not re-introducing anhedonia. Each one either failed to relieve WD or brought back anhedonia (the serotonergic ones)

4) Re-stabilized on Paxil at 15mg

5) Tried augmenting Wellbutrin (only increased anxiety), Vyvanse/Adderall (works for anhedonia, but the crash is brutal) low-dose Zyprexa (bad rxn), low-dose abilify (no effect), cyproheptadine (precipitated withdrawal), mirtazapine (knocked me out), Tianpetine (no effect) in attempt at relieving anhedonia through boosting dopamine directly or indirectly through targeted serotonin receptor blockade)

6) Tapered down to 7.5mg as of October 2016. More energy, anhedonia/loss of emotions remains apart from short windows.

7) Attempted Nortriptaline to paxil trapper to boost motivation and reduce anhedonia (it acts like an NRI, with target serotonin blockade at the "bad" receptors)

8) Stopped Nortriptaline after increased anxiety, no effect on anhedonia, and increased withdrawal symptoms. Only positive was alleviating ADHD symptoms.

9) Now struggling with a simultaneous Libirum and Paxil WD/taper...