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About reinstating and stabilizing to reduce withdrawal symptoms


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#109 Henosis

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Posted 07 September 2016 - 10:22 PM

Alto, have you gotten your emotions back after your reinstatement? You wrote in some thread that you were on Paxil first few years and then you were off for an year and then you started Paxil again and on the second time on Paxil it blunted your emotions. I wanted to ask this bc you have been off Paxil after you CT'ed for so long and bc so so many experience anhedonia after reinstatement.


This was my exact experience.. Never had anhedonia until reinstatement. Didn't realize this was a common thing?!

Medication before problems: Took Paxil 60-100mg from 2003 to 2014 for OCD.
1) Last pill taken November 2014, horrendous withdrawal started six weeks later.

2) Re-instated successfully @ 20mg May 2015, but accompanied by severe anhedonia, loss of emotion, apathy, and fatigue

3) Switched to Prozac, Viibyrd, Zoloft, Nefazadone, Cymbalta, Nardil in attempt at abating WD symptoms while not re-introducing anhedonia. Each one either failed to relieve WD or brought back anhedonia (the serotonergic ones)

4) Re-stabilized on Paxil at 15mg

5) Tried augmenting Wellbutrin (only increased anxiety), Vyvanse/Adderall (works for anhedonia, but the crash is brutal) low-dose Zyprexa (bad rxn), low-dose abilify (no effect), cyproheptadine (precipitated withdrawal), mirtazapine (knocked me out), Tianpetine (no effect) in attempt at relieving anhedonia through boosting dopamine directly or indirectly through targeted serotonin receptor blockade)

6) Tapered down to 7.5mg as of October 2016. More energy, anhedonia/loss of emotions remains apart from short windows.

7) Attempted Nortriptaline to paxil trapper to boost motivation and reduce anhedonia (it acts like an NRI, with target serotonin blockade at the "bad" receptors)

8) Stopped Nortriptaline after increased anxiety, no effect on anhedonia, and increased withdrawal symptoms. Only positive was alleviating ADHD symptoms.

9) Now struggling with a simultaneous Libirum and Paxil WD/taper...

 


#110 Altostrata

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Posted 09 September 2016 - 12:18 PM

Alto, have you gotten your emotions back after your reinstatement? You wrote in some thread that you were on Paxil first few years and then you were off for an year and then you started Paxil again and on the second time on Paxil it blunted your emotions. I wanted to ask this bc you have been off Paxil after you CT'ed for so long and bc so so many experience anhedonia after reinstatement.

 
This is incorrect. I never reinstated Paxil myself. After going off Paxil in October 2004, I suffered acute withdrawal syndrome for about 11 months and post-acute withdrawal syndrome for another 10 years. My emotions gradually came back in the last half of that period.
 
Please take discussions of drug-induced symptoms to such topics as these:
 
Did antidepressant reinstatement work for you?

Anhedonia, apathy, demotivation, emotional numbness
 
Disconnect between interest and action/motivation
 
Derealization or Depersonalization
 
Personality changes during withdrawal, who's had them?

"Change the channel" -- dealing with cognitive symptoms...

"Is it always going to be like this?"

What does healing from withdrawal syndrome feel like?

Inactivity may make sympathetic nervous system hypersensitive...
 
Non-drug techniques to cope with emotional symptoms


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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#111 akrontes

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Posted 02 October 2016 - 10:03 AM

I quit cold turkey 100 mg zoloft(sertraline) in May. One week went down to 50mg then stopped completely. Since then has been a downward trajectory, the first month was actually not so bad, symptoms really started to get bad after 2 months, and have been getting worse ever since. Reinstating has been on my mind, but I dont think I would risk it at this point and dont really think I am considering it seriously as an option after 4 and half months.


cannabis: Spring 2002 - Dec. 2007; regularly smoked, stopped cold turkey; symptoms: paranoid and depressed

Paroxetine: 20 mg July 2008, 40 mg October, 20 mg spring 2009, 0 mg summer 2009

Depakote (sodium valproate): October 2008 - Spring 2009

Haloperdidol 1 week Oct. 2008, H caused seizures, went to A&E;  stopped taking it.

Citalopram few weeks in the fall of 2009 to deal with withdrawal symptoms from stopping paroxetine

Paroxetine round 2: 20 mg Feb - summer 2010 -20mg don't remeber if I went up to 40mg

Venlafaxine & sodium valproate (again): Sep 2010 - Summer 2012  

SERTRALINE: November 2012 - May 2016 , 50-100mg (few days @ 150mg in Summer '15). a complete freak out at the end of April. 

May 2016 Prescribed Lithium and aripiprazole HAVE NOT TAKEN

No medications May 2016 - October 2016

Hospitalised - November 13th - 15 mg Mirtazapine until  6th December, decreased to 7.5 mg

Since 24 December been shaving off a little each day.  Now taking approx. 4 mg or 1/4 of 15 mg tablet.  Stopped reducing further for the moment


#112 Henosis

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Posted 02 October 2016 - 03:20 PM

YMMV, but I reinstated at 4/5 months to keep my job. And I did it in a terrible way (tried all kinds of other drugs before going back on the original) and it "worked" for me. 90% of the symptoms went away or were greatly improved, saved for adding fatigue and anhedonia.

Medication before problems: Took Paxil 60-100mg from 2003 to 2014 for OCD.
1) Last pill taken November 2014, horrendous withdrawal started six weeks later.

2) Re-instated successfully @ 20mg May 2015, but accompanied by severe anhedonia, loss of emotion, apathy, and fatigue

3) Switched to Prozac, Viibyrd, Zoloft, Nefazadone, Cymbalta, Nardil in attempt at abating WD symptoms while not re-introducing anhedonia. Each one either failed to relieve WD or brought back anhedonia (the serotonergic ones)

4) Re-stabilized on Paxil at 15mg

5) Tried augmenting Wellbutrin (only increased anxiety), Vyvanse/Adderall (works for anhedonia, but the crash is brutal) low-dose Zyprexa (bad rxn), low-dose abilify (no effect), cyproheptadine (precipitated withdrawal), mirtazapine (knocked me out), Tianpetine (no effect) in attempt at relieving anhedonia through boosting dopamine directly or indirectly through targeted serotonin receptor blockade)

6) Tapered down to 7.5mg as of October 2016. More energy, anhedonia/loss of emotions remains apart from short windows.

7) Attempted Nortriptaline to paxil trapper to boost motivation and reduce anhedonia (it acts like an NRI, with target serotonin blockade at the "bad" receptors)

8) Stopped Nortriptaline after increased anxiety, no effect on anhedonia, and increased withdrawal symptoms. Only positive was alleviating ADHD symptoms.

9) Now struggling with a simultaneous Libirum and Paxil WD/taper...

 


#113 Newbeginning

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Posted 02 October 2016 - 08:20 PM

Reinstatements have been a lifesaver for me. I've had to updose a bit at several points in my taper when my body couldn't handle my previous taper schedule.

 

The relief I feel immediately after reinstating (generally the day after) is the only thing that gives me hope to keep going.

 

I've read at benzo forums that one should never reinstate repeatedly because it can cause kindling. I understand how that could happen, and every reinstatement carries risk, but I just couldn't remain minimally functional without reinstating. Neither would I been able to keep cutting, as unstable as I was for weeks and months.

 

So in MY case, reinstatements helped me stabilize, continue tapering, and function.


  • SSRIs 3-4 times in the last 14 years; would take them for 6-8 months and then taper off under dr supervision with no problems.
  • Med history prior to 2015: http://survivinganti...313#entry267313
  • 04/2015: Prozac decreased to 15mg over last 3 months; effexor held steady at 8mg; current effexor XR: 20 beads of a 75mg capsule per day (about 8mg)
  • 06/2015: Prozac: 10mg; effexor XR: 19 beads (about 7.5mg); 07/2015: Prozac: 8.5mg; effexor 18 beads; 08/2015: Prozac: 7.5mg; effexor: 17 beads
  • End of August: withdrawal: depressive symptoms, crying spells. Realized I was measuring prozac dose wrong for the last 2 months. Reinstated Prozac 8.5mg; Kept effexor at 17 beads. Stabilized in 5 weeks.
  • 10/2015: Prozac: 8.5mg; effexor: 17 beads
  • 11/2015: Prozac: 1.9ml (7.5mg); effexor: 16 beads
  • 12/2015: Prozac: 1.6ml; effexor xr: 16 beads. Withdrawal: neuroemotions
  • 01/2016: prozac: 1.6ml; effexor xr: reinstated 17 beads, withdrawal improved; 02/2016: Prozac 1.5ml; Effexor: 17 beads; 03/2016: Prozac 1.3ml(5mg); Effexor: 17 beads (7mg)-withdrawal (flu-like malaise, lightheaded, drowsy) started end of March. April 15: reinstated Prozac 1.5ml. Stabilized. 2 weeks ok. End of April: Withdrawal (neuroemotions). Eventually stabilized in April-May. Apathy improved.
  • 3 month hold until August. August 2016: apathy came back;

  • October 2016: updosed to Prozac 1.6ml. Bad reaction: anxiety, depression. End of October: went down Prozac 1.5ml. Stabilized over several weeks.

  • Dec 9: tried macca for energy: anxiety/depression. Improved over several weeks, but not completely resolved.

  • Dec 31: cut Effexor 5% to 16 beads. After 9 days: withdrawal anxiety, depression

     


#114 woof

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Posted 29 October 2016 - 03:07 AM

How long should you give reinstatement?

  • After reinstatement, the amount of time needed to alleviate withdrawal symptoms (stabilizing) varies according to the individual. Relief can be felt immediately, after some weeks, or after some months.
  • Once you feel withdrawal symptoms are reduced after reinstatement, give your nervous system time to stabilize before attempting dosage reduction. Think in terms of months, not days.
  • Be patient after you reinstate. Reinstatement may not immediately eliminate all withdrawal symptoms. You may still experience waves of symptoms, which usually lessen as time goes on.

 

Altostrata,

 

I was wondering if perhaps adding the sentence, "...Do not attempt to taper again until you feel symptom-free...." to your post above from 2013 post below to the post above, might perhaps be helpful for some who are not as familiar with the difference in the terms, stabilize vs. symptom free and begin tapering prior to being "symptom free."

 

Most Respectfully and Sincerely,

Woof

 

 

 

Altostrata

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Posted 03 May 2013 - 02:34 PM

You need to let your nervous system stabilize after reinstating. How long this might take depends on how long you've been off the drug and other factors. If you were off only a couple of days, you might stabilize for a month before trying to taper. If you've been off longer, to be safe, you should give your nervous system longer to stabilize, even if symptoms go away right away. If you've been off months, it might take months before you stabilize. Do not attempt to taper again until you feel symptom-free. (Cold turkey off another psych drug simultaneously compounds the situation.)

2004-2015 Cymbalta 20mg/d No problems at all with Cymbalta, I just wanted to get off of all meds.  Nov, 25 2015 CT 20mg/d Cymbalta (194 beads)   

Jan 2016 Reinstated 20mg/d Cymbalta (194 beads) 5 weeks after CT

Jan-April 2016 Held Cymbalta 20mg/d for 4 months. All wd sx's gone, except: 4/10 AM anxiety 9-1:30 only after 7:30 AM Cymbalta, 2/10 tinnitus & 2-4 AM waking then back to sleep. 

April 21 2016 Prematurely CUT -Cymbalta 20-18mg (194-19 = 175 beads) - AM anxiety resolved :)  May 21, 2016 cut to (158 beads) 16mg-stable,

July 04, 2016 cut to (143 beads) 14.5mg and had 10/10 wd sx's  Anxiety, Anhedonia, Anorexia, Fear, dysphoria, could not go back to sleep after 1:30 AM wake-up.

Nov 29th 2016 UPDOSED (41 beads) Cymbalta to 20mg (194 bead) all sxs except tinnitus virtually gone. 

I plan to stay on 20mg/d Cymbalta.  Nothing but improvement since updosing.  Stable with no anxiety and greatly improved sleep as of March 8th 2017

FEB 2016 STARTED Valium 25mg/d for the CT Cymbalta wd sxs.   August 2016 Increased Valium to 28mg/qhs, due wd sx's from July 4, 2016 Cymbalta cut.

Jan 1, 2017  Cut Valium 28mg qhs 28mg-3mg=25mg.    March 11,2017 25mg-2mg=23mg   Plan to decrease Valium 10% per 4 weeks as tolerated.  Fish oil

http://survivinganti...key-withdrawal/  Benzo Posts http://survivinganti...ta-wd-symptoms/

 

 


#115 Altostrata

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Posted 29 October 2016 - 10:15 AM

Good point, woof. I made the change.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#116 MNgal1960

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Posted 05 November 2016 - 07:42 PM

Questions:

 

Does this advice apply the same way to someone who only tapered part way and is still on the med but considering reinstating to the original dose? Especially the advice about being sensitized to the drug.

 

Does the reinstatement advice apply to all psych meds, not just antidepressants? (In my case, Seroquel.)

 

Is it really possible to be symptom-free?

 

Thanks.

 

MN


2005-2006 Rapid taper off of Zoloft. Horrible but survived. Adverse drug reaction to Prozac.

2010-2013 Night panics. All typical sleep aids failed. Diagnosed with complex PTSD.

2013-present: Valium (5mg x 3) prescribed by pro-benzo doctor. Helped me sleep for awhile. Then sleep began to get worse again.

Nov. 2014 Switched doctors. New doctor was anti-benzo but thought a 3-month taper was a slow taper. Failed and reinstated. Added 25mg Seroquel for sleep.

Sept. 2015 Made occasional very small dry cuts to the Seroquel. Down to 20mg. Did not notice much change in symptoms.

March 2016 Reduced gabapentin by 20% by accident and backed up again. (Was trying to feel less sedated.) Reduced again more slowly to 200+200+300.

Sept 2016 Down to 16.5mg of Seroquel. Disabling neuropathy and sleep poor. Backed up to 19mg. Improved.

October 2016 Liquefied one V tablet. Neuropathy back immediately. Waiting to liquefy another.

November 2016 All 3 tablets now dissolved. I think the windows are getting a little more frequent but they don't last long. Sleep poor.

January 2017 Felt stable enough to try daily microtaper. Started at 3% and inched up to almost 10%. Became very unstable. Terrors back. Neuropathy back.

February 2017 Holding again. Slow improvements.

March 2017 Neuropathy back to tolerable. Making very tiny cuts, about 3%/month.


#117 Altostrata

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Posted 06 November 2016 - 12:52 PM

If you are tapering and get withdrawal symptoms that don't go away in a few days, a small updose might help. You may not need to go back all the way to the original dosage to quell withdrawal symptoms.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#118 ChessieCat

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Posted 06 November 2016 - 02:00 PM

"Is it really possible to be symptom-free?"

 

The idea of reinstatement and updosing isn't to become free of symptoms but to get the withdrawal symptoms to a bearable level.


Podcasts:    Let's Talk Withdrawal

 

Antidepressants:  25 years - 1 unknown, Prozac (caused muscle weakness), Zoloft; Cipramil CTed (very sick for 2.5 wks soon after)

Pristiq:  50mg mid 2012, 100mg beg 2014 (mild Serotonin Toxicity)     Current:  Pristiq 28mg (from 3 March 17)

 

Tapering history & graph

My website - includes my brief history + links to videos & information on the web

 

I've still got a way to go ... but I've already come a long way!!!

 

PLEASE NOTE:  I am not a medical professional.


#119 MNgal1960

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Posted 06 November 2016 - 02:16 PM

Thanks, Chessie and Alto. Right now I'm thinking I will try to stick it out for another week at current levels.

 

MN


2005-2006 Rapid taper off of Zoloft. Horrible but survived. Adverse drug reaction to Prozac.

2010-2013 Night panics. All typical sleep aids failed. Diagnosed with complex PTSD.

2013-present: Valium (5mg x 3) prescribed by pro-benzo doctor. Helped me sleep for awhile. Then sleep began to get worse again.

Nov. 2014 Switched doctors. New doctor was anti-benzo but thought a 3-month taper was a slow taper. Failed and reinstated. Added 25mg Seroquel for sleep.

Sept. 2015 Made occasional very small dry cuts to the Seroquel. Down to 20mg. Did not notice much change in symptoms.

March 2016 Reduced gabapentin by 20% by accident and backed up again. (Was trying to feel less sedated.) Reduced again more slowly to 200+200+300.

Sept 2016 Down to 16.5mg of Seroquel. Disabling neuropathy and sleep poor. Backed up to 19mg. Improved.

October 2016 Liquefied one V tablet. Neuropathy back immediately. Waiting to liquefy another.

November 2016 All 3 tablets now dissolved. I think the windows are getting a little more frequent but they don't last long. Sleep poor.

January 2017 Felt stable enough to try daily microtaper. Started at 3% and inched up to almost 10%. Became very unstable. Terrors back. Neuropathy back.

February 2017 Holding again. Slow improvements.

March 2017 Neuropathy back to tolerable. Making very tiny cuts, about 3%/month.


#120 Revenge

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Posted 10 December 2016 - 05:07 AM

This is cool, very helpful. I was off for a long time, several years. I cold-turkeyed for the most part, and I was on a heavy-duty "cocktail." I believe my brain was damaged by taking the drugs, not from withdrawal. Stopping them any way I could saved my life.

 

I had none of the "brain zaps" people describe. Insomnia resulted from decades on drugs. After five years of barely sleeping at all, I finally decided I couldn't stand constant exhaustion. My mood was not affected, but I tended to be short-tempered because I could barely stay awake. I recall feeling that I would fall asleep while walking and doing ordinary tasks. I also dropped things that were in my hands due to mini-sleeps.

 

I obtained some Seroquel without a prescription (not quite legally) and started back at the lowest possible dose. It was like a miracle. My goal is to get off, but really, I'm so thrilled to sleep that I am less worried about the drug damage from such a low dose than I am about the devastating consequences of sleep deprivation. I think the only way I can taper would be to grind it up (it isn't XR) and dissolve it in water, then drink, and do a very very very slow taper even from this mini-dose.



#121 ChessieCat

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Posted 10 December 2016 - 03:19 PM

Hi Revenge,

 

Welcome to SA.  You might like to start your own Intro/Update topic (topic right & click on Start New Topic) so you can journal your progress and get support from the SA community.


Podcasts:    Let's Talk Withdrawal

 

Antidepressants:  25 years - 1 unknown, Prozac (caused muscle weakness), Zoloft; Cipramil CTed (very sick for 2.5 wks soon after)

Pristiq:  50mg mid 2012, 100mg beg 2014 (mild Serotonin Toxicity)     Current:  Pristiq 28mg (from 3 March 17)

 

Tapering history & graph

My website - includes my brief history + links to videos & information on the web

 

I've still got a way to go ... but I've already come a long way!!!

 

PLEASE NOTE:  I am not a medical professional.


#122 Mellie

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Posted 01 January 2017 - 05:46 PM

If a low-dose reinstatement doesn't seem to be helping after a couple of weeks, is it necessary to taper or can you stop immediately?


  • 1998-2002 - High dose of Luvox for 4.5 years. Rapid taper over a couple of months in early 2002. Not much withdrawal issues, other than increased irritability and mood lability for a few months.
  • 2005 - Brief trial of Wellbutrin. Stopped taking it after a few months with no problems.
  • 2008 - Started fluoxetine (Prozac), 10 mg. Took this dose for several years. At some point upped the dose to 20 mg and maintained until late 2015.
  • November 2015 - Cold turkeyed off of Prozac 20 mg. Experienced low energy, lack of motivation, irritability, but these were symptoms I was experiencing while still on the SSRI (albeit to a lesser degree).
  • May 2016 - 6 months later, late-onset withdrawal symptoms appear. Severe anxiety, insomnia, dread, unprecedented feelings of hopeless depression, suicidal ideation, bouts of crying, nausea, loss of appetite, akathisia (feeling like I'm vibrating internally, but no need to move).
  • June - September 2016 - Symptoms continue. Mostly waves, but some windows. Some recovery.
  • October - November 2016 - Diagnosed with breast cancer. Handled fairly well, but resorted to benzos for sleep in the week prior to surgery. Following surgery, was pretty out of it for 3 weeks on pain pills and antibiotics.
  • December 2106 - Withdrawal symptoms back with a vengeance, especially anxiety, insomnia, suicidal ideation, and depression. Oncologist prescribed 10 mg Lexapro. Took 2.5 mg for 2 weeks, but felt it was making anxiety worse, so stopped. 
  • January 2016 - Restarted 2.5 mg Lexapro after realizing it was the antibiotic I was taking that was making things worse, not the SSRI. Have stabilized to a large degree.

 


#123 woof

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Posted 03 January 2017 - 12:27 PM

Some (like me) may have never have had any problems with Cymbalta... until I Ct'd off. 

 

So for me, being free of symptoms, was my goal and I was hopeful that reinstatement would do so - It was just going to take longer than I had expected, so I prematurely began to taper after 4 months of a full dose reinstatement.

 

It's now been 6 weeks since my full updose to 20mg/d Cymbalta and this is the best I've felt in over a year. 

 

My only sx now is 2-3/10 tinnitus.

 

I hope this helps,

Woof out

 

 

How long should you give reinstatement?

  • After reinstatement, the amount of time needed to alleviate withdrawal symptoms (stabilizing) varies according to the individual. Relief can be felt immediately, after some weeks, or after some months.
  • Once you feel withdrawal symptoms are reduced after reinstatement, give your nervous system time to stabilize before attempting dosage reduction. Think in terms of months, not days.
  • Be patient after you reinstate. Reinstatement may not immediately eliminate all withdrawal symptoms. You may still experience waves of symptoms, which usually lessen as time goes on.

 


2004-2015 Cymbalta 20mg/d No problems at all with Cymbalta, I just wanted to get off of all meds.  Nov, 25 2015 CT 20mg/d Cymbalta (194 beads)   

Jan 2016 Reinstated 20mg/d Cymbalta (194 beads) 5 weeks after CT

Jan-April 2016 Held Cymbalta 20mg/d for 4 months. All wd sx's gone, except: 4/10 AM anxiety 9-1:30 only after 7:30 AM Cymbalta, 2/10 tinnitus & 2-4 AM waking then back to sleep. 

April 21 2016 Prematurely CUT -Cymbalta 20-18mg (194-19 = 175 beads) - AM anxiety resolved :)  May 21, 2016 cut to (158 beads) 16mg-stable,

July 04, 2016 cut to (143 beads) 14.5mg and had 10/10 wd sx's  Anxiety, Anhedonia, Anorexia, Fear, dysphoria, could not go back to sleep after 1:30 AM wake-up.

Nov 29th 2016 UPDOSED (41 beads) Cymbalta to 20mg (194 bead) all sxs except tinnitus virtually gone. 

I plan to stay on 20mg/d Cymbalta.  Nothing but improvement since updosing.  Stable with no anxiety and greatly improved sleep as of March 8th 2017

FEB 2016 STARTED Valium 25mg/d for the CT Cymbalta wd sxs.   August 2016 Increased Valium to 28mg/qhs, due wd sx's from July 4, 2016 Cymbalta cut.

Jan 1, 2017  Cut Valium 28mg qhs 28mg-3mg=25mg.    March 11,2017 25mg-2mg=23mg   Plan to decrease Valium 10% per 4 weeks as tolerated.  Fish oil

http://survivinganti...key-withdrawal/  Benzo Posts http://survivinganti...ta-wd-symptoms/

 

 


#124 KarenB

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Posted 08 January 2017 - 06:47 PM

Sorry for the delay in answering Mellie - I wanted to check with the other mods. 

 

If a low-dose reinstatement doesn't seem to be helping after a couple of weeks, is it necessary to taper or can you stop immediately?

 

It would pay to taper, but it can be done at a faster rate than the usual 10% monthly (unless w/d symptoms indicate otherwise).  You could try reducing by 25%, waiting a week and assessing how you are feeling.  If all is good, try another 25% and so on.  If symptoms increase, that is a clear sign to slow the taper. 

 

Of course if you are already suffering from previous drug changes, that is another reason to taper carefully.  A sudden stop can make things much worse. 


2010 May Fluoxetine 20mg. Raging mostly stops, become more functional.
2011 February Escitalopram 10mg (sudden switch). 2012 January Escitalopram 20mg.  2013 Early June Feeling great, decide to taper. Doc advises alternate days 20mg/10mg for 4 weeks.  Late June Steady. Drop to 10mg daily. Early July Not coping, raging, flu symptoms, shaky, anxious, low, spaced-out, self-destructive.  Mid July Return to alternate days 20mg/10mg - minimal improvement. Early August Return to full dose 20mg. Lost.
2014 February Switch to Venlafaxine. (First reduced Esc. to 10mg/day for a week) Feb-April Lost, 'light' self-harm, exhausted.
April Increase Ven. to 150mg/day. Dizzy. July 75mg twice a day to improve dizziness. Deep depression remains.  2015 Feb Vigilant dose spacing partially eases dizziness. Mar Switch to Effexor 75mg 2x/day. May Cut 10% to 135mg - bad w/d 2 mths, held 1 mth.  Aug 1.3% cut - bad 1mth, held 1mth. Oct 4 wkly 0.4% cuts held 6 weeks. Jan 2016 2 wkly 0.4% cuts. 8 month hold. Sept Wkly cuts: 0.5%, 3 1% cuts.  Oct 4 wkly 1% cuts, hold 3-4 weeks.
Supplements: Fish oil, vitamins E & C, magnesium, iron, MSM, oat-straw tea, nettle tea.  My story of healing: ContinuedHealing

***I am not a doctor or counselor; please do your own research and be prepared to take responsibility for decisions you make.*** 

           'The possibility of renewal exists so long as life exists.'  Dr Gabor Mate.


#125 Mellie

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Posted 08 January 2017 - 06:59 PM

Thanks, Karen. That makes sense.

 

But what if the low-dose reinstatement causes a bad reaction (as opposed to simply not helping with withdrawal issues)? Then would you stop immediately? This is what Dr. Shipko advised elsewhere, especially if akathisia increases.

 

What are your thoughts?


  • 1998-2002 - High dose of Luvox for 4.5 years. Rapid taper over a couple of months in early 2002. Not much withdrawal issues, other than increased irritability and mood lability for a few months.
  • 2005 - Brief trial of Wellbutrin. Stopped taking it after a few months with no problems.
  • 2008 - Started fluoxetine (Prozac), 10 mg. Took this dose for several years. At some point upped the dose to 20 mg and maintained until late 2015.
  • November 2015 - Cold turkeyed off of Prozac 20 mg. Experienced low energy, lack of motivation, irritability, but these were symptoms I was experiencing while still on the SSRI (albeit to a lesser degree).
  • May 2016 - 6 months later, late-onset withdrawal symptoms appear. Severe anxiety, insomnia, dread, unprecedented feelings of hopeless depression, suicidal ideation, bouts of crying, nausea, loss of appetite, akathisia (feeling like I'm vibrating internally, but no need to move).
  • June - September 2016 - Symptoms continue. Mostly waves, but some windows. Some recovery.
  • October - November 2016 - Diagnosed with breast cancer. Handled fairly well, but resorted to benzos for sleep in the week prior to surgery. Following surgery, was pretty out of it for 3 weeks on pain pills and antibiotics.
  • December 2106 - Withdrawal symptoms back with a vengeance, especially anxiety, insomnia, suicidal ideation, and depression. Oncologist prescribed 10 mg Lexapro. Took 2.5 mg for 2 weeks, but felt it was making anxiety worse, so stopped. 
  • January 2016 - Restarted 2.5 mg Lexapro after realizing it was the antibiotic I was taking that was making things worse, not the SSRI. Have stabilized to a large degree.

 


#126 KarenB

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Posted 09 January 2017 - 09:46 PM

Absolutely.  From the first post in this thread: 

 

When to discontinue reinstatement
If, upon reinstatement, you very soon feel worse, most likely you are sensitized to the drug and need to take a smaller dosage or, possibly, none at all.

  • Sometimes reinstatement does not work. The nervous system has taken such a hard hit from withdrawal, it's destabilized beyond whatever effect the drug might have had.
  • Sometimes reinstatement not only does not work, it causes an adverse reaction from a nervous system sensitized by withdrawal.
  • If you have an immediate bad reaction, reduce or stop taking the drug.

2010 May Fluoxetine 20mg. Raging mostly stops, become more functional.
2011 February Escitalopram 10mg (sudden switch). 2012 January Escitalopram 20mg.  2013 Early June Feeling great, decide to taper. Doc advises alternate days 20mg/10mg for 4 weeks.  Late June Steady. Drop to 10mg daily. Early July Not coping, raging, flu symptoms, shaky, anxious, low, spaced-out, self-destructive.  Mid July Return to alternate days 20mg/10mg - minimal improvement. Early August Return to full dose 20mg. Lost.
2014 February Switch to Venlafaxine. (First reduced Esc. to 10mg/day for a week) Feb-April Lost, 'light' self-harm, exhausted.
April Increase Ven. to 150mg/day. Dizzy. July 75mg twice a day to improve dizziness. Deep depression remains.  2015 Feb Vigilant dose spacing partially eases dizziness. Mar Switch to Effexor 75mg 2x/day. May Cut 10% to 135mg - bad w/d 2 mths, held 1 mth.  Aug 1.3% cut - bad 1mth, held 1mth. Oct 4 wkly 0.4% cuts held 6 weeks. Jan 2016 2 wkly 0.4% cuts. 8 month hold. Sept Wkly cuts: 0.5%, 3 1% cuts.  Oct 4 wkly 1% cuts, hold 3-4 weeks.
Supplements: Fish oil, vitamins E & C, magnesium, iron, MSM, oat-straw tea, nettle tea.  My story of healing: ContinuedHealing

***I am not a doctor or counselor; please do your own research and be prepared to take responsibility for decisions you make.*** 

           'The possibility of renewal exists so long as life exists.'  Dr Gabor Mate.


#127 AlienResources

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Posted 05 February 2017 - 07:37 PM

Is +32 hours an immediate reaction?


02/08-04/15: Psychedelics - no problems ever
01/12-09/13: Sedation dentistry w Halcion - 12 appts
01/15-04/15: Screw around with Phenibut, Noopept, Alcohol
04/15: First panic attack
04/15-Pres: Xaxax 0.25-0.75mg as needed for PA monthy
06/15-03/16: Ambien 5-10mg /night
04/16-06/16: Successful taper Ambien 5mg to 0. Withdrawal never goes away.
09/16-12/16: Xanax 0.25mg 1-2 times week, Benadryl 25-75mg per night
       GI problems. On and off Prilosec + Zantac which interacts w Xanax.
01/17: CTd the intermittent Xanax and Benadryl.  Insomnia fibromyalgia twitching anxiety.
       Intermittent Ambien about every other night at avg dose of 4mg
02/17: Remeron - Experiment w doses between 1 - 7.5mg. Trying to get off Ambien


#128 Altostrata

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Posted 05 February 2017 - 08:03 PM

Hello, AlienResources. Thanks for starting an Intro topic. Let's take this conversation to your Intro topic.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

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#129 MNgal1960

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Posted 10 February 2017 - 06:22 AM

I'm curious if anyone knows if reinstatement typically helps or typically makes a person worse.


2005-2006 Rapid taper off of Zoloft. Horrible but survived. Adverse drug reaction to Prozac.

2010-2013 Night panics. All typical sleep aids failed. Diagnosed with complex PTSD.

2013-present: Valium (5mg x 3) prescribed by pro-benzo doctor. Helped me sleep for awhile. Then sleep began to get worse again.

Nov. 2014 Switched doctors. New doctor was anti-benzo but thought a 3-month taper was a slow taper. Failed and reinstated. Added 25mg Seroquel for sleep.

Sept. 2015 Made occasional very small dry cuts to the Seroquel. Down to 20mg. Did not notice much change in symptoms.

March 2016 Reduced gabapentin by 20% by accident and backed up again. (Was trying to feel less sedated.) Reduced again more slowly to 200+200+300.

Sept 2016 Down to 16.5mg of Seroquel. Disabling neuropathy and sleep poor. Backed up to 19mg. Improved.

October 2016 Liquefied one V tablet. Neuropathy back immediately. Waiting to liquefy another.

November 2016 All 3 tablets now dissolved. I think the windows are getting a little more frequent but they don't last long. Sleep poor.

January 2017 Felt stable enough to try daily microtaper. Started at 3% and inched up to almost 10%. Became very unstable. Terrors back. Neuropathy back.

February 2017 Holding again. Slow improvements.

March 2017 Neuropathy back to tolerable. Making very tiny cuts, about 3%/month.


#130 Flowers

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Posted 12 February 2017 - 07:24 AM

My experience was a good one with reinstatement of an AD.

I had done a too fast taper as per my GP and had some really awful debilitating symptoms that made me lose the use of my legs for a while.
I had got down to 10mgs of Citalopram before WD hit and went up to 20mgs and then my full dose of 30mgs before I was fully aquainted with SA.

I got some relief from the symptoms straight away and after a few months was feeling a lot better. I still had ups and downs though and held for a year before starting a taper.

I tapered successfully for a year until Dec 2016 when something went wrong and I am now struggling again and trying to stabilise.
15 yrs on 20 to 30 mgs CITALOPRAM
MAY 2014   Increased to 40mgs
SEPT-NOV 2014 tapered in 6 weeks down to 10mgs as per Dr's instructions due to violent nightmares/palpitations
 Given Noctamid (lormetazepam) to help with anxiety. On average took 2mg per day for 8 weeks.No taper was advised.
DEC 2014 WD severe. Nervous tic in eyes, limbs, muscle pain, fluct. temp,weakness,depression,anxiety,nausea,giddy,
Walking like I am drunk.
DEC 2014 Different Dr suggested taking 20mgs CIT. BROMAZEPAM 3mgs up to 3 x daily for anxiety.
DEC 9 2014 Updose CIT to 30mgs. Only taking BROMAZEPAM in emergency.
DEC 31 2014 Settling at 30mg CIT - helping with depression. Haven't taken any BROMAZEPAM for 2 weeks +.
APR 2015 Trying to stabilise on 30mgs CIT.
JAN 2016 CIT:Started taper. Reducing by 5%. 28.5mgs 
FEB  Taper held bereavement. APR Taper resumed 27mgs . MAY 25.50 mgs .  JUNE 24 mgs .  JULY I stupidly mixed up my BP meds with CIT. Consequently took no CIT for 3 days and doubled my BP meds. Waiting for the fallout....Holding for a while until any chance of repercussions have abated. SEPT taper resumed to  22.5 mgs . OCT 21 mgs .NOV 19.95 mgs. FEB 3rd updose to 20.5 mgs to try to stabilise.FEB.switched over to 75mgs of Venlafaxine XR for 3 weeks.Too stimulating so switching back to Cit. 12 March 37.5 Ven and 20 Cit.

#131 woof

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Posted 12 February 2017 - 12:02 PM

It's now been 6 weeks since my full updose to 20mg/d Cymbalta and this is the best I've felt in over a year. 

 

My only sx now is 2-3/10 tinnitus.

 

I hope this helps,

Woof out

 

 

How long should you give reinstatement?

  • After reinstatement, the amount of time needed to alleviate withdrawal symptoms (stabilizing) varies according to the individual. Relief can be felt immediately, after some weeks, or after some months.
  • Once you feel withdrawal symptoms are reduced after reinstatement, give your nervous system time to stabilize before attempting dosage reduction. Think in terms of months, not days.
  • Be patient after you reinstate. Reinstatement may not immediately eliminate all withdrawal symptoms. You may still experience waves of symptoms, which usually lessen as time goes on.

 

 

I am not sure; however, Alto's post above may also apply to tapering a med other than the one which was reinstated (or updosed in the situation below) as well .

 

I am now 2.5 months out from my full reinstatement to 20mg Cymbalta on Nov 29 2016, which went quite smoothly.

 

I had been advised by a well known psychiatrist to hold on any Valium cut for a few more months or more, even though I was feeling so good to allow the my brain to become more stabilized after the Cymbalta updose.

 

However, my prescribing MD was insistent on beginning the Valium taper as of Jan 1 2017, as I had now been on the Valium for almost a year at 25mg/d.

 

Unfortunately, 2.5 weekw after the Valium cut I now have developed some pretty nasty depression which does not go away; along with a 8/10 4-5 AM panic attack (PA) and sometimes an addtional PA later in the day.  Also I am now hypersensitive to any stress. 

 

My understanding is that these sx's may occur in any Benzo taper, I just don't know if waiting would have made the sx's less severe, but IMHO believe so.

 

My experience indicates that the psychiatrist (who unfortunately does not live in my state) was correct regarding my updose of Cymbalta and probably to delay the taper of another drug, eg Valium in this case, for a few months or more.  I hope this may be helpful to someone else.

 

Warmest Regards,

Woof :)


2004-2015 Cymbalta 20mg/d No problems at all with Cymbalta, I just wanted to get off of all meds.  Nov, 25 2015 CT 20mg/d Cymbalta (194 beads)   

Jan 2016 Reinstated 20mg/d Cymbalta (194 beads) 5 weeks after CT

Jan-April 2016 Held Cymbalta 20mg/d for 4 months. All wd sx's gone, except: 4/10 AM anxiety 9-1:30 only after 7:30 AM Cymbalta, 2/10 tinnitus & 2-4 AM waking then back to sleep. 

April 21 2016 Prematurely CUT -Cymbalta 20-18mg (194-19 = 175 beads) - AM anxiety resolved :)  May 21, 2016 cut to (158 beads) 16mg-stable,

July 04, 2016 cut to (143 beads) 14.5mg and had 10/10 wd sx's  Anxiety, Anhedonia, Anorexia, Fear, dysphoria, could not go back to sleep after 1:30 AM wake-up.

Nov 29th 2016 UPDOSED (41 beads) Cymbalta to 20mg (194 bead) all sxs except tinnitus virtually gone. 

I plan to stay on 20mg/d Cymbalta.  Nothing but improvement since updosing.  Stable with no anxiety and greatly improved sleep as of March 8th 2017

FEB 2016 STARTED Valium 25mg/d for the CT Cymbalta wd sxs.   August 2016 Increased Valium to 28mg/qhs, due wd sx's from July 4, 2016 Cymbalta cut.

Jan 1, 2017  Cut Valium 28mg qhs 28mg-3mg=25mg.    March 11,2017 25mg-2mg=23mg   Plan to decrease Valium 10% per 4 weeks as tolerated.  Fish oil

http://survivinganti...key-withdrawal/  Benzo Posts http://survivinganti...ta-wd-symptoms/

 

 


#132 catnapt

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Posted 12 February 2017 - 01:07 PM

I'm curious if anyone knows if reinstatement typically helps or typically makes a person worse.

 

I can only speak for myself, I jumped off at 2.5 and crashed about 5 mos later, and successfully  reinstated.

And by successful, I mean it pulled me out of the worst of things, when I had over 40 symptoms, all severe, for weeks.

 

I think I'd have been a LOT better off if I'd done a proper taper, for me, the reinstatement helped tremendously

 

I also reinstated at an extremely low dose, so that may have something to do with it.

I have been staying more or less stable now at well under 1mg of liquid lexapro


1974-2002 many psych meds, all types; longest used drugs include lithium, seroquel, SSRI's zoloft & celexa; many CT's off drugs

2002-2015 on varying doses of lexapro, as  high as 40 mgs, but usually 20mgs

June 2015: tapered too fast to 2.5mgs, then to 2.5mgs every other day Dec 2015:  found SA forum; holding at 2.5mgs 

Early May 2016: jumped off at 2.5mgs, not smart- crashed in late Sept.

Oct 26 2016  reinstated liquid lexapro 0.05ml/day at night, dose +/- til settling on 0.15BID (0.3/day)= windows and waves

Jan 8, 2017 too quick switch to single dose in the morning, 0.3mgs (bad mistake, led to a crash)

Jan 12 added low dose zyprexa for SI, took infrequently as rescue med, last dose Feb.15

Jan 26 lexapro 0.27mg Feb 25 lexapro updose back to 0.3mg due to unrelenting severe insomnia

March 1 insomnia got worse, back down to 0.29 for one day, then 0.27, then 0.25- improving!! March 17 0.24

March 7 added low dose lamictal, titrated up to 25mgs March 25

Supplements: vit D-3, Magnesium taurate 250mg, chromium, pro-biotic, biotin, valerian root, L-theanine


#133 Mellie

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Posted 12 February 2017 - 02:44 PM

I just wanted to check back in with an update. I CT'd from 20 mg Prozac in November 2015, then started having the horrible hyper-alerting symptoms in May 2016 (insomnia, anxiety, agitation, dread, depersonalization). I whiteknuckled my way through nearly 8 months of these symptoms, with windows and waves. However, I got really bad after I was diagnosed and had surgery for breast cancer in November 2016. By December, I was in a very dark, dangerous place. 

 

I couldn't reinstate Prozac, because it interferes with an important cancer drug, tamoxifen, that I'll be taking for the next 5-10 years. So I tried a small dose of Lexapro: 2.5 mg. This was a little more than 13 months after my CT. After two weeks, I stopped, because I feared it was making my anxiety and insomnia worse. But since then, I've figured out it was the fluoroquinolone antibiotic I was taking that was making things worse (I was on it for a month).

 

I went back on 2.5 mg of Lexapro on January 16. Since, then my symptoms have gotten much better. Suicidal ideation, dread, and depersonalization are gone. Anxiety is much better. And sleep has improved. This despite the huge stress of dealing with cancer and also having gone on another antibiotic for two weeks (azithromycin -- which also caused increasing anxiety and agitation while I was on it).

 

So reinstatement worked for me -- even with a different medication after a long SSRI-free gap. I don't plan on upping my dose. I just want to stabilize while I get through my medical crisis, and so far it is definitely helping.


  • 1998-2002 - High dose of Luvox for 4.5 years. Rapid taper over a couple of months in early 2002. Not much withdrawal issues, other than increased irritability and mood lability for a few months.
  • 2005 - Brief trial of Wellbutrin. Stopped taking it after a few months with no problems.
  • 2008 - Started fluoxetine (Prozac), 10 mg. Took this dose for several years. At some point upped the dose to 20 mg and maintained until late 2015.
  • November 2015 - Cold turkeyed off of Prozac 20 mg. Experienced low energy, lack of motivation, irritability, but these were symptoms I was experiencing while still on the SSRI (albeit to a lesser degree).
  • May 2016 - 6 months later, late-onset withdrawal symptoms appear. Severe anxiety, insomnia, dread, unprecedented feelings of hopeless depression, suicidal ideation, bouts of crying, nausea, loss of appetite, akathisia (feeling like I'm vibrating internally, but no need to move).
  • June - September 2016 - Symptoms continue. Mostly waves, but some windows. Some recovery.
  • October - November 2016 - Diagnosed with breast cancer. Handled fairly well, but resorted to benzos for sleep in the week prior to surgery. Following surgery, was pretty out of it for 3 weeks on pain pills and antibiotics.
  • December 2106 - Withdrawal symptoms back with a vengeance, especially anxiety, insomnia, suicidal ideation, and depression. Oncologist prescribed 10 mg Lexapro. Took 2.5 mg for 2 weeks, but felt it was making anxiety worse, so stopped. 
  • January 2016 - Restarted 2.5 mg Lexapro after realizing it was the antibiotic I was taking that was making things worse, not the SSRI. Have stabilized to a large degree.

 


#134 LexAnger

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Posted 13 February 2017 - 12:09 AM

So good to hear that RI lex worked for you Mellie!
This confirmed my guess about a greater chance of success in RI a different ssri as opposed to RI the same drug. For reasons we don't know, RI the same drug has greater probability of getting a reaction. I know it can't be generalized for 100% assurance, but many people changed ssri by their doctors when the old one is poopout, and many got severe reaction going back to their original ssri even at significantly smaller dose.

It's possible that even different SSirs block the same receptors, the molecular binding mechanism can be different so a different ssri can still work while the old one is fully exhausted.

Of course, this is nothing proved, only statistics from the uncontrolled random but massive incidences.

Don't know if agreeable by others, in case this is true, it can help with a less risky RI for those CTed and those got severe reaction being forced to CT.
<p>2009 Mar.: lexapro 10mg for headache for 2 weeks.2009-2012: on and off 1/4 to 1/3 of 10mg2012 June--2013 Jan,: 1/4-1/3 of 10mg generic, bad jaw pain2013 Jan-Mar: 10 mg generic. severe jaw and head pain; Mar--Aug. started tapering (liquid ever since) from 10 to 5 (one step) then gradually down to 2.25 mg, first ever panic attack, severe head/jaw pain2013 Aug.: back to 2.75 mg; Nov: back to Brand Lex. 2.75mg -- 3mg, slight improvement with pain2014 June: stopped PPI, head pressure/numbness. up-dosed 4.5mg, severe reaction mental symptoms added on2014 Aug--2015 Aug: Micro taper down to 3.2mg, .025mg (<1%) cut holding 2-3 weeks.2015 Aug 15th, Accidental one dose of 4.2mg. worsening brain non-functional, swollen head, body, coma like, DR2016 Feb., started fast taper for the drug toxicity caused by the one dose of 4.2mg, dosing 10am through 11 pm everyday2/13--3.2mg, 3/15-- 2.9mg, 4/19-- 2.6mg, 6/26--2.2mg, 7/22 --1.9mg, 8/16--1.8mg,8/31--1.7m g, 9/13--1.6mg, 9/27--1.5mg, 10/8--1.4mg, 10/14--1.3mg, 11/1--1.2mg, 11/29--1.1mg, 12/12--1mg, 12/22--0.9mg2017: 1/7--0.8mg, 1/15--0.7mg, 1/17--0.6mg, 1/20--0.52, 1/21--0.4mg, 1/22--0.26, 1/23--0.2, sliding Down to 0.13mg by 2/13, then 0.07mg since 2/18, 0.06mg 2/20-3/17, 0.13mg 3/18

#135 Altostrata

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Posted 13 February 2017 - 01:06 AM

That's good to hear, Mellie.

 

LexAnger, I don't believe it's true that a different SSRI is more effective as a reinstatement. There's so much variability among people, it's impossible to predict exactly what will happen, so we look to the history as a guide. Generally, it's best to reinstate a drug that was well tolerated before rather than to introduce a new drug that may cause adverse reactions, which will complicate the situation greatly.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

#136 LexAnger

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Posted 13 February 2017 - 01:55 AM

Alto, I believe you know the best. Only after reading so many who got severe reaction after RI the original drug, myself included by one increased dose, and many people on SSirs switching From one to another for decades not getting reactions, I can't help but thinking that something mysterious in the play of the RI. You are absolutely right about the incredible variabilities not just across individuals but also within. I feel it will never be clear even with so called controlled studies, as the whole thing is super dynamic moment by moment beyond the most complicated mathematic modeling.

Like all statistics, there will be always a probably of error when dealing with individual cases. So a guessing game with higher chances is all we can do.
<p>2009 Mar.: lexapro 10mg for headache for 2 weeks.2009-2012: on and off 1/4 to 1/3 of 10mg2012 June--2013 Jan,: 1/4-1/3 of 10mg generic, bad jaw pain2013 Jan-Mar: 10 mg generic. severe jaw and head pain; Mar--Aug. started tapering (liquid ever since) from 10 to 5 (one step) then gradually down to 2.25 mg, first ever panic attack, severe head/jaw pain2013 Aug.: back to 2.75 mg; Nov: back to Brand Lex. 2.75mg -- 3mg, slight improvement with pain2014 June: stopped PPI, head pressure/numbness. up-dosed 4.5mg, severe reaction mental symptoms added on2014 Aug--2015 Aug: Micro taper down to 3.2mg, .025mg (<1%) cut holding 2-3 weeks.2015 Aug 15th, Accidental one dose of 4.2mg. worsening brain non-functional, swollen head, body, coma like, DR2016 Feb., started fast taper for the drug toxicity caused by the one dose of 4.2mg, dosing 10am through 11 pm everyday2/13--3.2mg, 3/15-- 2.9mg, 4/19-- 2.6mg, 6/26--2.2mg, 7/22 --1.9mg, 8/16--1.8mg,8/31--1.7m g, 9/13--1.6mg, 9/27--1.5mg, 10/8--1.4mg, 10/14--1.3mg, 11/1--1.2mg, 11/29--1.1mg, 12/12--1mg, 12/22--0.9mg2017: 1/7--0.8mg, 1/15--0.7mg, 1/17--0.6mg, 1/20--0.52, 1/21--0.4mg, 1/22--0.26, 1/23--0.2, sliding Down to 0.13mg by 2/13, then 0.07mg since 2/18, 0.06mg 2/20-3/17, 0.13mg 3/18

#137 MNgal1960

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Posted 13 February 2017 - 05:39 PM

In my case, I was considering reinstating Seroquel to my original level. I've never reinstated an a/d. Just suffered until it was over. But that was a long time ago and there weren't groups like this to help.

 

I'm glad to read of those who were helped.


2005-2006 Rapid taper off of Zoloft. Horrible but survived. Adverse drug reaction to Prozac.

2010-2013 Night panics. All typical sleep aids failed. Diagnosed with complex PTSD.

2013-present: Valium (5mg x 3) prescribed by pro-benzo doctor. Helped me sleep for awhile. Then sleep began to get worse again.

Nov. 2014 Switched doctors. New doctor was anti-benzo but thought a 3-month taper was a slow taper. Failed and reinstated. Added 25mg Seroquel for sleep.

Sept. 2015 Made occasional very small dry cuts to the Seroquel. Down to 20mg. Did not notice much change in symptoms.

March 2016 Reduced gabapentin by 20% by accident and backed up again. (Was trying to feel less sedated.) Reduced again more slowly to 200+200+300.

Sept 2016 Down to 16.5mg of Seroquel. Disabling neuropathy and sleep poor. Backed up to 19mg. Improved.

October 2016 Liquefied one V tablet. Neuropathy back immediately. Waiting to liquefy another.

November 2016 All 3 tablets now dissolved. I think the windows are getting a little more frequent but they don't last long. Sleep poor.

January 2017 Felt stable enough to try daily microtaper. Started at 3% and inched up to almost 10%. Became very unstable. Terrors back. Neuropathy back.

February 2017 Holding again. Slow improvements.

March 2017 Neuropathy back to tolerable. Making very tiny cuts, about 3%/month.