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  1. This seems to be a very common symptom of withdrawal syndrome. Many people report waking up with a surge of panic or anxiety, or a feeling of anxiety early in the morning. A lot of times, people are waking around 4:30 a.m. or closer to dawn. The first glimmers of morning light signal the nervous system to start the morning cycle with a jump in cortisol. At normal levels, cortisol gives you energy. At elevated levels, cortisol gives you a feeling of unease, anxiety, panic, or depression. When you have withdrawal syndrome, your system is on "high alert" all the time. The normal morning peak of cortisol gets exaggerated and what you would normally feel as "wake up" becomes a surge of panic, anxiety, or dread in the early morning.

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