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Found 120 results

  1. Tapering calculator at ReversePsychiatry.org

    Announcing.. Reverse Psychiatry - Taper a calculator
  2. Treating akithisia

    Hey all, I just discovered that the restlessness, jitteriness, and anxiety that I started to experience when I started taking Lexapro has a name: akithisia. I was only on Lexapro for 2.5 months and I felt akithisia the whole time. I totally stopped the Lexapro about 2 months ago and I get occasional bouts of akithisia. I've read online about different things that can treat it like taking Benadryl, vitamin B supplements, propanol, etc. Anyone have any advice for what works best for them?
  3. PatriciaM: Glad to get to know you

    Hi. I am new here, slowly tapering at 2.5% (first week). Are there REALLY any people who have successfully made it and are now 100% Effexor free and feeling good? This is my 5th attempt and I am not sure if all this process if it is worth it or not. Maybe because I can't talk about this withdrawal with my doc, partner or my kids. Everybody is against this. Any input would be welcome.
  4. Hey guys First of all I’m astounded by the amount of compassion members give to each other on this site. You’re all very beautiful people and I thank you for doing what you do. My drug history can be found in my signature but basically I've been on Zoloft/Sertraline 150 mg for OCD for almost 2 years now and I've experienced very mild side effects, namely increased sweating, yawning and eyes watering. My condition had improved tremendously - before then I was constantly plagued by my worries and could not function, so I decided to begin tapering off. In November 2017 I reduced my dose to 125 mg (on GP's advice). On December 14 2017 I masturbated for the first time in years, then felt extremely guilty afterwards as I have read online that people have developed PGAD due to sertraline. Ever since I stumbled upon stories about PGAD in the 8th grade, I've been afraid of this disorder. I hoped that the feelings of arousal would go away in a few minutes, as they always did in the past after I 'entertained', so I tried to calm myself down and distract myself by playing video games. To my dread the feelings were still there. There's a constant urge to urinate, throbbing, pulsing sensations in my genitals, clitoris whatever it is. I just graduated from high school and I'm still a virgin so I have no idea what an actual orgasm is like, but after that incident I just randomly experience the 'climaxes' I get during masturbation. I believed it was nerve related because if I tried to do an activity that was more intellectually stimulating, the arousal feelings would become stronger. It was very difficult to concentrate. However I noticed that the arousal feelings were weaker at around dinnertime, before I take my daily dose but came back after I took the sertraline. These symptoms arose just as I was on holiday overseas to a third world country where psychiatry isn’t really practised safely if at all, so I couldn’t see a doctor. Distressed and desperate to do something about it, I skipped my meds for a day (NEVER DO THIS) and the feelings disappeared, which confirmed my theory that sertraline was causing the PGAD-like sensations. On 27 December 2017 I stupidly reduced the dose to 100 mg without a doctor’s consultation, not knowing it was likely a symptom of withdrawal. This in itself did not make the sensations go away, but I was able to change my ‘mindset’. January 2018: Seeing as the feelings were less noticeable when I was under pressure to socialise, I began to force myself to ‘think quick’ and pretend that I was under that same pressure. With this mindset, the PGAD feelings were completely gone and I was ecstatic. However on the plane ride back home, this mindset caused me to have migraines, so I no longer adopted that mindset, yet the PGAD did not come back! Another win! However this was proved wrong as after a few days it returned and with it, the hopelessness and depression. My GP suggested that I go back up to 150 mg and I was so down and suicidal that my mum and I agreed. I felt weird and uncoordinated on such a high dose so I went down to 125 mg which I am currently at. I’m going to see a new psychiatrist soon hopefully. Applying a different mindset doesn’t keep the PGAD at bay any longer. Before I even started the meds I’ve had almost constant migraines which is most likely anxiety related. Recently I’ve been able to make the PGAD go away by thinking about my headaches in a different way (it’s really complicated and difficult to describe), so it is probably due to the meds changing my brain chemistry, changing nerve pathways. I’m currently more emotionally stable. I want to ask does staying at 125 mg for another month sound like a good plan, then tapering off veery slowly (I didn’t know about the 10% rule back then)?
  5. My third and hopefully final attempt to get off Paxil is here I start March 1st of this year, which is just around the corner. I have a lot of hope It will be over 3 years, but I feel good about my taper plan. Thankful for this site of encouragement and testimonies - I will be praying for freedom for you all! I've included a photo of my handwritten taper plan. The length of time is in months. Will keep this updated for whoever cares to read. Let's do this.
  6. Diehard: tapering

    Hello brave souls, After various other antidepressants I started Paxil (20mg) seven years ago and augmented with Mirtazapine (30mg) 4 years ago. In the interim I still suffered feelings of hopelessness, worthlessness and all the signs of Dysthymia so what was the point of the medication? Poor concentration and performance wrecked my career and emotional impulsiveness caused many problems in my marriage. I cannot understand why my dear wife of 37 years is still with me? I retired 4 years ago due to stress and depression but now at the age of 70, finally I have had enough antidepressants making me more depressed! I’m in my third week of reducing Paxil down to 15mg, so far so good. Although I have read many horror stories about weaning off Paxil, I am confident I will succeed if I go slowly. Drinking lots of water, daily walking, along with a good diet and reading all the brave success stories from this site will get me through. I know it! Once the Paxil is out of my system, Mirtazapine is next! I know it won’t be easy but I’m looking forward to the challenge. I thank all you brave soldiers for your encouragement and advice. Peace be with you!
  7. Hi everyone, I am taking Effexor for chronic pain not depression. On Effexor for 10 years, half of those years on 112.5mg the other half 150mg Started reducing a year ago February 2012 - 150mg March 2012 - 131mg April 2012 - 112.5mg July 2nd 2012 - 92mg July 23rd - chronic pain got worse October 21st - started 75mg (chronic pain flare up subsided and has been stable ever since) November 16th - 56mg December 11th - 37.5mg January 5th, 2013 - 19mg January 22nd, 2013 - 22.5mg January 23rd, 2013 - 37.5mg January 24th, 2013 - 30mg From November 16th when I dropped to 56mg up to January 22nd the withdrawal effects gradually got worse. Prior to this I experienced no withdrawal effects. On January 22nd when I increased the dosage to 22.5mg I was trying to decrease the withdrawal effects because they were getting too strong. The small increase had no effect. On the following day when I increased to 37.5mg after an hour and 45 minutes the withdrawal effects got significantly worse. I went to my family Doctor (who was much more knowlegeable than I thought) and he recommended taking 30mg. Today I feel slightly better than yesterday but still not as good as when I was on 19mg. I'm wondering if I should stay at 30mg or should I decrease to maybe 25mg since I felt better at 19mg and I was on 19mg for 2 and half weeks? Any advice would be greatly appreciated. Best of health to everyone! Thank you!
  8. Hi, After reading many many posts, I'm more confused than ever ... I just obtained a prescription to have Pristiq compounded and reduced by 10% of current dose each month in hopes of getting off this beast. After reading some of the posts, it appears that it may not be a good idea to compound this drug because of the extended release properties of the 50mg pill. Is there anyone on this site that has had success tapering off of this drug using a compound pharmacy to do a 10% taper per month? I"m now nervous to get the prescription filled after reading some of the posts. I contacted the compound pharmacy (Guardian Drugs in Toronto, Canada) and they have the same reservations about crushing the extended release tablets as they tell me, that while they can do it, they don't know exactly how the compounded drug with react in my system. In compounding it, the drug will most likely be weaker (by exactly how much they can't say with any accuracy) and therefore she cannot say with any certainty whether or not it will cause withdrawal symptoms which I am desperate to avoid. Tried to taper off about five years ago (second or third try) by cutting the pill and reducing it gradually and had such bad withdrawal symptoms, I thought I was going to go mad so back on the stupid drug I went. The compounding pharmacy offered to call my family doctor and suggest to her that I switch to Effexor (75mg) which she said is equivalent to 50mg of Pristiq. She said that Effexor is much easier to come off of and much easier to compound. She said it didn't sound like my family doctor has much experience with coming off antidepressants (don't think my doctor is alone on this point). She also suggested reducing the Effexor by 5% each month rather than 10% to help avoid withdrawal altogether. She said it is better to taper very gradually and to take as long as possible to get off these drugs. Even a year or more sounded reasonable to her. So I guess my questions are (1) is it feasible/best approach to switch to Effexor to taper or am I just switching to a different beast even more difficult to get off of? (2) should I just get the Pristiq compounded and hope for the best ... ? (3) better suggestions/experience than the above two points? I would really like to get off of Pristiq, have been on anti-depressants far too long and never able to get off of them properly because of the horrific withdrawal symptoms so basically I've been held hostage by a little pill and would like my life back. Tired of feeling flat and not having any real emotions and don't want to Stepford Wife/Walking Dead it anymore. I've been taking 50mg of Pristiq for about 7 years and prior to that was on Effexor extended release 37.5 x 2 for about the same amount of time. Any suggestions from people with experience getting off these drugs would be most welcomed and appreciated. Thank you for reading.
  9. Hi my name is Sherry and I am on my second day of tapering off of Gabapentin 400 2x daily. I have been on it since last September. I have gained 28 lbs. on this jacked up medication. I just can't sit around and wait until it's even more out of hand. If anyone has already gone through it please leave me any helpful tips. I have the capsules and I have cut down to 400 in am and 200 at night. Thanks.
  10. I'm holding at .25 mg of clonazepam twice a day. Since September 2017 have been slowly tapering down from .5mg , 3 times a day from Aug 2017. The madness started when I tried to taper off 1 mg of xanax 3 times a day in May 2017 . I could not taper off xanax , even with a trial of ativan or valium both intolerable. 2 mg dose of valium caused uncontrollable shaking of body and stuttering when speaking . Ended up in Aug 2017 , in hospital , pulled off xanax, thrown on mirtazepiene , gabapentin and clonazepam . Have slowly tapered off the gabapentin and mirtazepiene, one at a time . I need help in lowering my dose of clonazepam , because have been holding for 30 days + due to on and off internal vibrations , and the start of warming spine with tingling , assorted chills on and off, etc . My fear is the next taper will bring constant burning of spine , as had with xanax , and worse the reinstatement of gabapentin. Gabapentin did stop burning spine but with depression, blurred vision, weight gain and acne like eruptions on face and neck , as well as other side effects , etc. I need help on my next drop . Do I just stay where I am at and hope the internal vibrations, tingling , and warming spine at some point stop ? I'm very strong and determined to be free of this drug but do not know how to endure burning nerve pain from withdrawal . I have tried topical magnesium oil , oral melatonin for sleep , Ubiquinal , etc to no avail. Ubiquinal at low dose reved me up , just to stimulating . Who knows if placebo effect , but tart cherry juice , twice a day allows for some sleep. I find my body during tapering, less is more and fear supplements cause more harm due to a very sensitive nervous system. I do take vitamin b with c and vitamin d . I follow a low cholesterol diet , no alcohol or caffeine . My DR. does not believe in protracted withdrawal or that my symptoms stem from benzos . A neurologist disagrees as thankfully no neurological damage just neurological symptoms every time a cut in dose is made . Does any one have any insight to ease my suffering ?
  11. Can anyone speak or advise upon whether 5HTP or Tryptophan can be used during the withdrawal process and at what point should they be applied?
  12. Hi, I started this topic a while ago and it has been 6 months now since my last dose of Prozac, so I'd like to share the way I used to taper so may be someone out there benefit from it, However I'd like to point out that I'm not a doctor and that this worked for me merely through trial and error, so here we go. As I mentioned in my first topic my first tapering attempt was too fast that I had awful withdrawal symptoms and had to reinstate, and the 10% approach was too slow for me as I was able to make larger drops without much symptoms, I then found the following research paper here on the forums: It's a paper on the percentage of serotonin transporter occupancy of Prozac (and other SSRIs) in the brain, in other words it basically measures the amount of serotonin receptors in the brain blocked by the medication, at 20mg most SSRIs will block 75%-85% of these receptors. After going through the paper I found that the percentage for Prozac occupancy follows the following equation: Occupancy% = 86*dose/(1.94+dose) So for example, if you take 20mg Prozac, the approximate occupancy% = 86*20/(1.944+20) = 78%, and so on. What I did next was finding the maximum percentage I can go down without suffering too much withdrawal symptoms, and with some trial and error I found this percentage to be 8%, meaning if I'm currently at 78% I can go down to 70% without much withdrawal symptoms, any higher and the symptoms are unbearable. So I prepared a table with 8% drop downs, calculated the dosage for every percentage and stayed on every dosage from 2-4 weeks depending on the symptoms, this worked perfectly for me as I was able to calculate the next dosage that wouldn't cause much symptoms, for example I was able to drop directly from 20mg to 10 mg and from 10mg to 5mg, however as the dosage decreased the drops where slower to maintain the 8% drop, this also allowed me to know when to stop taking the medication completely, for example at 0.5mg I was still at 18% so I had to drop to as low as 0.1mg before stopping completely. My last dose was on 17/4/2017, I had to make 14 drops over the course of a year, and although I had a couple of hiccups toward the end I was able to get through them by staying a little longer on the dosage and doing lots of exercise.
  13. Psychiatrist has told me to stop Sertraline from 150, down to 100mg the next week, then down to 50 the next, then stop (not because my depression has eased but because it doesn't seem to have helped at all. However, online I see that people are recommending a much longer tapering. . The problem is, when I rang the surgery today to try and voice my concerns about this and some other things I wasn't sure about, I was told by one of the staff to just follow what the psychiatrist says. I tried telling her that I had to go away for three months to work in a place where I have no friends, family or doctor, but she didn't seem to want to listen. Does anyone have any thoughts on this? Is this too quick a time period and if not, aren't I just dependent on whatever a certified doctor tells me to do?
  14. Hi everyone. I am hoping to get some much needed (and very much appreciated) advice on my situation. As you see, I had been on Sertraline for almost 2 years, or around the two year mark, before I began a too fast taper in 2016 which lead to my withdrawal syndrome in September 2016. My doctor had me taper in 6 weeks completely off Sertraline, jumping off at 25mg and not even tapering the 25mg, just cold turkeying the 25 per his instruction. Well, I was feeling some withdrawal symptoms, I just didn't realize what they truly meant, and my doctor had told me not to worry 'they will clear up in a few weeks" well they didn't really clear up, but actually got worse two-three months later. I want to make this as short as possible so it is easy to read, but long story short, I ended up reinstating Sertraline at 12.5mg first week, at the same time tapering the 30mg of buspirone my doctor had tried to test out on me for almost two weeks. Each week, he upped my dose of Sertraline during my reinstatement, until I reached 57mg and my body rejected anything above the 57mg. However, I did not know anything about withdrawal or tapering back then, and realize that I was put on way too high of a dose for reinstatement. This has me very scared and very anxious, I try hard not to be, and most of it is likely neuro related, but I wonder what I can do if I feel it's too high? I've got the anhedonia, but I've had this since December, and it actually was brought on more or less by my doctor trying to put me back up to 75mg, maybe that was just a coincidence, but I am not so sure. Each adjustment of the sertraline left me with worsened insomnia, worsened panic, trembling and what I can only describe as body jolts every morning for four months straight. And trying to sleep at night I felt like I was having seizures almost, where my body would jolt me awake just as I was drifting off to sleep, heart would be racing, fear and panic would run rampant and worsen in the morning. I still have mild teeth chattering every morning and especially when the anxiety or stress comes on. I reinstated pretty quick, where I reinstated as soon as my withdrawal symptoms started getting worse, I didn't wait it out even though I really wanted to. I didn't want to go back on the medication after what it had done to me, but didn't know what else to do. Then, everyone I trusted, my doctor especially, had me convinced I had developed several new mental disorders in a matter of three days. I was so so scared, and my anxiety was through the roof. I really stressed myself out a lot trying to figure out "what was wrong with me" because I did not know at the time. On top of that I had the professionals I trusted assuring me it was my "symptoms coming back" (they actually said that right after I already told them I never ever had these symptoms before in my life, not even one of them.) Then I happened to find SA, during my research into my symptoms and the ssri I was taking. I learned a lot in one night, and my jaw dropped. My gut had been telling me all this time it was the drug, it was withdrawal. But I ignored it and listened to the "experts" instead. HUGE MISTAKE!! Now I am stuck in a situation that makes me fear for the future, and not sure what I can do now that I am back on a higher dose. If I would've known better, I would not have allowed my doctor to titrate me up so high. I would've sat at the lowest possible dose, even the 12.5mg. My withdrawal symptoms had really settled down a lot for the last two or three months now though. My appetite came back, libido came back, depression lifted almost instantly upon reinstatement, the anxiety and panic took a while to lift but that has really settled down a ton and only sporadically (maybe lasting a second or two) I'll feel a blip of panic and anxiety (typically when under a lot of built up stress), and my biggest gripe for withdrawal symptoms as of now is the anhedonia, but even that was beginning to lift where I'd get moments of joy or contentment or my interests peaking through the veil of anhedonia. My sleep actually went back to normal in the last week or two, and I haven't been waking with the dread or anxiety for the past three months now, and I have been feeling pretty good except now I got back into this wave and I think it's because I'm stressing over tapering and my dosage after what I read last night. I read on SA someone said that being on too high a reinstatement dose can permanently damage your brain, where you will never heal from it. So I am really scared... I really need advice or wisdom on where to go from here. At this point, I worry I'll always feel this way and I'll never recover any further than where I currently am. I'd be fine if I felt somewhat normal, where I could handle the withdrawal symptoms temporarily until they pass, and I do admit that on my better days I certainly can handle them. But I feel like reinstatement was pointless or worse for me than just muscling through the withdrawals after what I read about high dose reinstatement. I feel like A) it's going to take forever just to stabilise on this dose and B it's going to be painful trying to taper when the time comes, due to that I may have permanently damaged my brain with my reinstatement. I guess what I am wondering now is, do I stay on this dose and wait for the anhedonia to completely go away, or how do I know when I am ready to begin tapering? At this point I am just feeling very confused and afraid about my dose and tapering in the future. I feel lost. I'd really appreciate any help! Thank you!
  15. Hello everyone. I was given a diagnosis of bipolar disorder during a difficult time in my life. The psychiatrist put me on lamictal, gabapentin, grapevine and Wellbutrin. Since then I've gotten sober and live a healthy lifestyle. I've been having bad side effects to the meds and told the psychiatrist I want to get off. She suggested doubling the dose of lamictal and adding an antipsychotic. She won't help me, so I found a holistic doctor and a chiropractor who are helping my taper. Got off the wellbutrin and tried with the gabapentin and was not able to continue because I could not function with the horrendous withdrawal symptoms. Currently tapering the grapevine and will take the landfall when I'm done with that. I need support and encouragement as I walk through this nightmare!! That's why I joined this group!
  16. Hi! I am new to the site and would love to hear from others going through the same journey! I am a 25 year old female, and have been on Lexipro 20mg for about 2 years and want desperately to get off of it. After I graduated from college, I was in a very bad place psychically and mentally (anxiety, eating disorder, depression), and my therapist recommend I take an anti depressant "temporarily". I took her advice, and agreed to try this "temporarily" while I continue to seek treatment. Nobody ever warned me about the negative side effects, and more importantly, how terrible and difficult it would be to get off! I am now happily married, have a great job, wonderful friends and family, and am sick of the side effects of this medication (low libido, lack of emotions). I asked my doctor if I could taper off, and she said "sure, take 10mg for a week, then go off completely". This seemed fast to me, which my therapist agreed, but I decided to trust my doctor and give it a try. I went from 20mg to 10mg for about 2 weeks with manageable withdrawal symptoms, then completely off 4 days ago. The symptoms are terrible!! All day I am experiencing brain zaps that send this electron shock like feeling throughout my whole body, dizziness, vertigo, headaches, strange vivid dreams, and nausea. They are almost unbearable, but at this point, I feel like I should stick it out. It would feel wrong to give in and put this terrible medication back in my body! Did I taper too quickly? How long with these symptoms last? Since I have already taken the step to go completely off, should I ride it out? Please help!! I really do not want to put this medication back into my body, but I also want to make sure I can fully recover and be off this for good. Any thoughts, advice, or shared experiences would be greatly appreciated! I really have not discussed this with many people, so feel pretty lost!! Thank you in advance!
  17. I was on flu 20mg for 17 weeks and during that time had horrific sides effects that included no appetite, constant diorreah, huge 4 hour panic attacks and scared to leave home and no sleep. After 3 months most went but sleep was still issue. I could get to sleep and stay a sleep if I used quitipine but that's not long term solution due to health risks. So doctor agreed to give me melatonin sleep hormone and halve my flu to 10mg on 2 november. Have had lovely 3 weeks of good sleep and no issues with mood. Last couple of days I've woke with panic, had erratic sleep, and now lost appetite again and have diarreah and low thoughts. I read flu withdrawal can take 3 weeks to kick in due to long half life. My question is do I continue with 10mg and see if withdrawal improves or go back to 20mg because when my body still had that in system along with melatonin I was functioning. I don't like the hair loss it was giving me either. Or another drug? Paroxetine worked in past but weight gain and painful withdrawal and sleepy all time. Just not sure what to do that will cause me least pain and effects as I'm single parent of a 5 year old and need to function
  18. I was on Prozac for around 6 and a half years, 50 percent of the time i was on two 20mg tablets and the other 50 percent i was on one 20mg tablet. I self tapered for around a month and a half by taking one every other day, then every 2nd day, then every 3rd day...etc and eventually i was off them. I took my last pill nearly a month ago. I am feeling withdrawals. Bloating, bad skin, rosacea-like symptoms, irritable, anger, aches and pains, negative thoughts. Its very uncomfortable and debilitating BUT i would be able to stick it through if i knew i was on the right path. I'm just worried that i messed up because of how fast i tapered. I don't know wether to keep going or if i should start taking prozac again and taper more slowly?
  19. Hello everyone! I am a new user here. I've lurked around this site before but have yet to introduce myself. I was a Prozac user for a year from August 2015 - September 2016. I had taken it for social and general anxiety. I was on 20mg/day. Initially, I was actually doing fine and great emotionally but had side effects like massive fatigue everyday (not even 3 cups of coffee could wake me up!) and constipation every time I went to poop (sorry for TMI). I also felt like a zombie for a brief period in which I was neither happy nor sad. In May 2016, I decided to abruptly stop taking the Prozac by choice without consulting my doctor (bad move!) and had brain zaps and mood swings which I assumed as worsening depression. I then just asked my doctor to simply increase my dose because I thought I was getting worse (bad move again!). I was put on 40mg/day from June - August 2016 in which I was ok at first but then I was hit with a panic attack so severe I had to rush to the ER. For that week, I was having very severe symptoms. So I was instructed to go back down to 20mg/day. From then on, I decided to stop taking it a few months ago in September because I felt better and didn't want to rely on medication anymore to make me happy. I consulted with my psychiatrist who said for me to just take 10mg for one month and then I can stop. I did just that. Over the month of October I was fine and felt completely normal. However, I realized symptoms would come later once the month of November started. I have since felt every type of symptom under the sun including brain zaps, hot flushes, insomnia, irritability, tingling sensation of the skin, anxiety, shortness of breath, sweating, tremors, and slight vertigo. I have never felt these symptoms in my life til now! I've talked to my doctor and he doesn't believe in withdrawals. At this point I feel helpless. I am experiencing waves and windows in which I have waves of really bad flare ups and then windows of good normal days where I feel fine. But they keep cycling back and forth. I now have questions to ask: 1. Do windows of no symptoms mean that my body is getting better? 2. Should I reinstate the Prozac and taper off more gradually? Someone suggested I shouldn't because I've already been clean for 3 months now. But what do you guys think? 3. Will symptoms go away if I keep pushing cold turkey? 4. Should I try medical weed to help ease tthe symptoms? I want to try natural ways of healing
  20. Here I go again, was finally over the withdrawal from the last drops and felt great for a month then decided to taper the paxil by 1.5mg and two weeks later here I am, morning anxiety, ears blocked, depression, irritable and a feeling of having sinus problems in my head. I just hate this and I realise I have so far to go.I read that a lot of people find it easy at the beginning of there taper but I’m finding it difficult and I think that’s because ever since that stupid DR cold turkey me off the paxil 3 years ago and had 3 months of servers withdrawal, it has done something to my nervous system. Now I’m so sensitive. I feel disheartened because someone said to me in another forum to stay on it if it makes me happy becouse that is what he would do, but I’ve been on this drug for 22 years and I’m only 40 years old and want to get as low as my brain will let me. When I’m in withdrawal I feel like giving up on tapering but then when I stablize I’m determined again. I think I just need some reassurance that I’m doing the right thing . Feeling disheartened ☺️
  21. Hello to the community, I've been reading and browsing this site for a while, but hadn't ever formally joined. I've been taking medication (Paxil then Effexor) for the past 15+ years. In the past year or two I've become much more emotionally healthy and have entered a stable place in my life. From many different discussions with different medical professionals (and from personal experience!) I know it is best to taper from a position of strength and relative good mental health and I've fought so so hard to get to where I am. I want to taper off of my medications to recover my emotions and to potentially try to become pregnant. I find that I've become much more emotionally blunted - I am neither happy nor sad about things that would be joyful/upsetting for most people. I am also at the age where many of my friends are having children, and would also love to have a child. From the literature searching that I have done, I've found many conflicting opinions on whether or not a pregnant woman should take mental health medications - Effexor XR in particular. I've consulted 3 MDs and one naturopathic doctor and have connected with MotherRisk at SickKids Hospital in Toronto. I have been told the following: My GP: you should switch to Celexa ( less side effects/ lower risk of birth defects/) 2nd Doctor: keep taking your medication (Effexor) - don't worry about it. Naturopathic doctor - difficult decision - there is no one right answer and each person must decide the level of risk that is acceptable to him/her and also balance your own mental health needs. SickKids RN - Keep taking your meds. Internet research - conflicting opinions, scary stories etc. Some children of mothers taking Effexor are born and have withdrawal symptoms. I want to stay out of judgement - I think everyone needs to do what is right for them. Right now, for me it feels right to try and taper. In the past 7 months I've tapered slowly down with the assistance of a mental health RN and Naturopathic doctor who advised supplements for the brain zapps. I feel like there are so many people who take medication for mental health, and so many women getting pregnant - but the issue of the two together is very rarely talked about, at least in my experience. If there is anyone out there who has gone through this issue, or has some experience I would love to hear about it. I have found a few articles, and I believe there was recently a film made called "Moms and Meds" although I haven't seen it yet... possibly because I don't want to sob quietly for 30 or 40 minutes before bed. https://broadly.vice.com/en_us/article/pg75mg/for-pregnant-women-with-mental-illnesses-medication-can-be-a-minefield Taking things one day at a time. Whee... Cokemachineglow
  22. staystrong: My story

    Hello comrades, In mid-June of 2017 was forced to ct all AD's as I was in a mess mentally ever since a reckless intern in a psych ward put me on 25mg of Thorazine to which I sustained some kind of brain damage. in 2007 I underwent neurological malignant syndrome due to a small dose of Geodon taken with 60mg. Nardil. (see my intro for more details) Anyway after the AD ct my reckless Dr. put me on 900mg. gabapentin but quickly dropped to 300mg. Now almost 4 months out I realize the GBN is making me more depressed. flat, anxious and stupid along with unrelenting blocked bowels. I made a drastic cut to 160mg and was suicidal, raging and my brain felt like sludge. Going to try a very slow taper once I get a script for liquid GBN. Anyway wondering if anyone else finds GBN makes them depressed and flat. Plus the extreme cog fog and constipation. Are there others who cannot safely taper at 10% or higher. Please I am so messed up right now I am basically bedbound. I currently take 300mg. GBN in the am. Would love some feedback..................peace to all................ss
  23. Hello! I would like to begin a very slow taper of Fluoxetine (10mg) about 7 years. Attempted two years ago but didn't do properly and doctors convinced me that it wasn't the reduction of medicine doing this to me (oodles of withdrawals). Reinstated to full dose. I am currently on tablet form. My question...I want to do a 10% conservative reduction. Should I continue on tablet and cut and weigh or should I transition to capsule and count beads ( not time release ).. Requested liquid from doctor but was told since I am on such a small dose liquid would be too difficult. I am nervous to begin this journey for fear of what happened before but am going to forge ahead. So....cutting and weighing pill or counting beads and weighing for capsule? Which will allow for a more accurate, easier very slow reduction and someday jump off??? Would appreciate feedback please!!!
  24. Hello All, Not sure if I am posting in the right section, so apologies in advance. I am feeling quite lonely within no one to turn to on the same wave length.. I've been trying to get hold of a shrink I started seeing a few months ago. Left 3 messages asking him to confirm our regular sessions after a holiday break but he has not responded. I know that he is around, as I dialled his number by mistake yesterday and he did answer it. Unfortunately, I couldn't talk as I was not calling him. Anyway... The very sad is that the fact of him not calling me back, makes me feel,.for some ridiculous reasons, inferior and a bad person! My worth depends on whether he calls me or not! I KNOW it's ridiculous and probably due to my general feeling down and out of sorts but this awareness doesn't makes much of the difference... I also feel like a "bad " person, this feeling I'd experienced even before taking the meds so it's not a withdrawal..Probably, this badness has some routs in my childhood, whatever, now it feels real as ever... Sorry for putting it out there, I don't know who to turn too. After all, my psychotherapist is ignoring me (probably I've done something wrong, "bad girl "). Anyway, thank you for reading it and any thoughts, words of the encouragement would be appreciated... F47 PS Really, getting disappointed with the psychoanalysts here in France..
  25. ADMIN NOTE Also see Tapering according to the serotonin transporter occupancy curve To search for whether there is a serotonin transporter occupancy study for your medication, google the generic name of the drug with this other search terms: 5HTT occupancy If you find a paper, please post the both the name of the medication and a link to the paper, such as 2016-July-01, Cymbalta (duloxetine) MMarie found this paper on dose and 5HTT occupancy. The site, academia.edu, requires login: http://www.academia....orter_occupancy Link to screen shot of dose-occupancy and dose-plasma concentration curves 2016-November-12, Anafranil (clomipramine) and Luvox (fluvoxamine) Link to study on occupancy vs. dose Link to chart of occupancy-dose relationship Hi, I thought I'd share this as it's quite relevant, not 100% sure if this is the right subforum, will post in both this and research. PDF of American Journal of Psychiatry article or Summary and excerpts from study in the Journals forum of survivingantidepressants The pretty pictures are from page 4 onwards in the PDF. (Admin note: Pretty pictures here. See this post for graph of "perfect" 10% taper of previous dose with 4 week holds) What these fellows did here, was attempt to measure serotonin transporter occupancy at various doses for 5 different drugs. (Zoloft, celexa paxil, effxor and Prozac, not in that order). They fit curves for both the oral doses and blood concentrations. Long story short for anyone who doesn't know, SSRI’s ‘work’ by binding to the serotonin transporter protein (SERT) and stopping it doing it’s normal thing (reuptake of post-synaptic serotonin), resulting in serotonin hanging around for longer. Now a couple of interesting things: -at minimum therapeutic doses in every case, there was about 80% SERT occupancy. That shocked me personally. Even the minimum doses are locking down 80% of your brains reuptake ‘capacity’. Higher doses do more but it’s obviously not linear – they actually have plotted curves, and they’re quite a good fit statistically, particularly for the blood concentrations. Really good in fact. Point here though is that there’s a long way between 0% at no drug and 80% at the minimum dose. -the curves man, look at the curves. This gives a fairly good indication of why some people find tapering necessary. You NEED a percentage taper just to get a linear decrease in SERT occupancy. Linear decreases in dose will actually hit you with exponentially increasing drops in SERT occupancy, particularly drops between the minimum therapeutic dose and 0 Basically, this paper provides a real basis for percentage reductions in dose when discontinuing SSRI’s. I realize I'm kinda preaching to the converted and telling people what they already know, but it seems there may actually be a real reason why some people find it necessary to do these percentage tapers to get off SSRI's. Caveat: I have no idea what the relationship between SERT occupancy and post synaptic serotonin is, it’s probably not linear since if it was higher doses would have basically no effect, but this is nevertheless very interesting to look at. They were only looking at one part of the brain but pointed out it correlated strongly to elsewhere.
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