Jump to content
Sign in to follow this  
Altostrata

Kennedy, 2009 Sexual dysfunction, depression, and the impact of antidepressants.

Recommended Posts

Altostrata   
Altostrata

The cause of antidepressant-induced sexual dysfunction is multfactorial, as many hormonal systems are disrupted.

 

J Clin Psychopharmacol. 2009 Apr;29(2):157-64. doi: 10.1097/JCP.0b013e31819c76e9.

Sexual dysfunction, depression, and the impact of antidepressants.
Kennedy SH1, Rizvi S.

Abstract from http://www.ncbi.nlm.nih.gov/pubmed/19512977Full text http://www.mediafire.com/download/t92z22kzoxrh3z7/09_Kennedy_Sexual_Dysfunction%2C_Depression%2C_and_Antidepressants.pdf

Sexual dysfunction is a common symptom of depression. Although decreased libido is most often reported, difficulties with arousal, resulting in vaginal dryness in women and erectile dysfunction in men, and absent or delayed orgasm are also prevalent. Sexual dysfunction is also a frequent adverse effect of treatment with most antidepressants and is one of the predominant reasons for premature drug discontinuation. Selective serotonin reuptake inhibitors are the most widely prescribed antidepressants and have significant effects on arousal and orgasm compared with antidepressants that target norepinephrine, dopamine, and melatonin systems. The availability of an antidepressant that does not cause or exacerbate sexual dysfunction represents an advance in pharmacotherapy for mood disorders and should reduce treatment noncompliance and decrease the need for switching antidepressants or adding antidotes. The purpose of this review was to provide an update on the prevalence, psychobiology, and relative adverse effect burden of sexual dysfunction associated with different antidepressants.

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
Sign in to follow this  

×

Important Information

By using this site, you agree to our Terms of Use.