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kurayami

kurayami: Quetiapine - what the hell?

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kurayami   
kurayami

I've been taking seroquel for PTSD for two years. I was taking 600 mg XR a day. In addition to this, I was taking a diabetes drug - metformin - to stop the outrageous hunger caused by seroquel. I've had a flare up of my eating disorder and decided that come hell or high water that I must get off the seroquel. Taking the combination of 600mg XR seroquel and 2000mg XR metformin, I managed to drop my weight down from a disgusting 72kg to a more tolerable 57kg (I'm 155cms tall) and stopped losing weight. No matter how much I restrict or exercise, I can't lose weight and haven't lost anything at all for 2 months. 

 

I did some research and decided to move across to Prazosin because it's also an alpha 1 adrenergic receptor antagonist like seroquel, but it's not sedating and doesn't cause you to gain weight or get metabolic syndrome either. So while I'm titrating up Prazosin at 2mg a day until I get to a dose of 30mg a day (I'm currently at 25 mg). But I've been simultaneously reducing my seroquel by 50mg a day - or I was until I completely lost my patience and remembering what my psychiatrist said about seroquel tapering, I started dropping my dose by 100mg every 5 days. For the most part, everything's been totally fine, except for a few days of insomnia.

 

Now that I've gone from 50mg XR to 0, it's hit the fan and I can't sleep. Like I can be tired and feel physically relaxed but my brain won't stop thinking and over thinking and I can't fall asleep no matter what I do. I generally pass out at about 5 am and sleep until maybe 9 am, if I'm lucky. Until the prazosin was titrated to above 20mg a day, I was completely and irrationally suicidal and had to take all of my medications to my pastor and ask him to look after them because I was convinced that I'd overdose on them.

 

I rang my psychiatrist and his only advice was to keep on with the seroquel and I absolutely refuse to do this. I feel like if I do that I'll a] never get off it and b] never lose any more weight. Will this insomnia go away? Or will I need to get an alternate drug to make me sleep until the seroquel is out of my system and my brain has adjusted? I just don't know what to do. University starts back in a week and I have to sleep if I expect to study. If I can't study, I can't eat because I'll lose my merit scholarship. IDK what to do.

 

Anyone got any ideas, advice, help?

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KarenB   
KarenB

Hello kurayami,

 

Lots going on for you right now, and with the pressure of uni starting too.  So glad you've found this site.  Read as much as you can on here - the more informed you become the more you'll be able to find and stick to a healing pathway. 

 

We recommend a gentle taper, reducing by no more than 10% of your current dose each month.  This allows your brain time to adjust as you go, and lessens any withdrawal.  The last part of any taper is usually the most difficult, and requires the most care.  At this point, the most helpful path for you is probably to reinstate the 50mg seroquel.  I know - it sounds backwards, but it's actually the best way to stabilise. 

 

We have a thread that discusses it here:http://survivingantidepressants.org/index.php?/topic/7562-about-reinstating-and-stabilizing-to-reduce-withdrawal-symptoms/  Once you were stable again you could taper off according to our 10% monthly guide.  And then you'd be better placed to address your weight and insomnia. 

 

Many people find Fish oil and Magnesium useful during withdrawal.   

Keep it Simple; Keep it Slow; Keep it Stable

Non-Drug Techniques to cope with emotional symptoms

Symptom Checklist

 

The troublesome thing with SSRIs is that you can't just flush their effects out of your system.  They change the way your brain works, and that takes much longer to heal.  Suddenly stopping the drug puts your brain and Central Nervous System into shock.  It's like yanking a trellis out of a garden instead of gently untangling the plants and slowly removing the wood – it’s too much trauma for the plants/your brain.  (For the source of that simile, plus further discussion, see http://survivinganti...el-your-brain/)

 

Have a read of those and then you can come back to this thread to discuss things further.  This can be your journal to record your tapering and healing progress, and to ask questions. 

 

Welcome to SA,

Karen

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