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Ryder

Ryder: Taking carnitine with SSRI's

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Ryder   
Ryder

Hi guys,

 

This question has to do with SSRI's and supplements.

 

I was diagnosed with Chronic OCD in January 2015. I have been on and off medication between 2009-2015.

Since 2015 I was prescribed 200mg (Sertraline/Zoloft) Daytime and 2mg Clonazepam for night time sleep. At the back-end-of 2016 I felt that I was

well enough to come of all medications as I just felt able enough to cope on 100mg after a while. I did Cold Turkey for most of it before admittingly and slowly going on the lower dose of 100mg Sertraline.

 

I was afterward sent to a Dr who specialised in withdrawing people from medications.

 

She prescribed:

 

- L-Carneitine (300 mg)

- CoQ10 (200 mg)

- N-Acetylcysteine

- Vitamin C

- Selenium

- Magnesium.

- A Gluten Free Diet.

 

With Gluten diet, I did not stick to this religiously as some of the books advocated here on this forum. Mainly Elaine Gotschall's Breaking the Viscious Cycle. (Specific Carbohydrate Diet) and the GAPS Diet advocated by Dr Natasha Campbell-Mcbride. I am very skeptical when i read over these diets but since my Dad was on the diet, whatever was in the Pantry, I ate. I wasn't religious about it though if I ordered takeout.

 

Back on topic, I reduced the supplements to L-Carneteine and CoQ10 in combination with SSRI Zoloft/Sertraline (100mg). I found that during the time taken them, I had trouble with Cognition and motor skills, driving, runnng and excercise. I also noticed that I couldn't stop feeling dizzy although they are supposed to aide mitochondria in the brain which the Zoloft dulls down. I also noticed real bad insomnia during the time taken these aided supplements.

 

Has anyone else had success with L-Carneteine and CoQ10 prescribed with Zoloft? It seems that people are having great success with these two supplements to rave review, I am just wondering if Carneteine or CoQ10 has worked for anyone to either reduce withdrawal symptoms off SSRIs & Zoloft or taper off completely.

 

 

**Note. I have looked through the other posts here, but most vary in opinion, so I just want this question answered.

 

 

Many thanks.

Ryder.

 

 

 

 

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Asjf   
Asjf

Have you checked out examine.com?

You can search just about any supplement there and get a lot of info. I don't see any evidence of CoQ10 having any cognitive benefits. L-Carnitine had a bad effect of me. Caused severe anxiety--which is understandable considering it can be stimulating.

 

https://examine.com

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Altostrata   
Altostrata

Welcome, Ryder.
 
I've moved your topic to the Introductions forum, as your Introductions topic. Please bookmark it or follow it; you can post your questions and updates in this topic.
 
That practitioner recommended an unusual bunch of supplements. I can't say I've ever seen that before, or why it might assist withdrawal from sertraline or any other SSRI.
 
If any supplement makes you feel odd in a bad way, I would stop taking it.
 
Are you interested in going off sertraline? Please read

Why taper by 10% of my dosage?

Tips for tapering off Zoloft (sertraline)
 
Our basic supplement kit:
 
King of supplements: Omega-3 fatty acids (fish oil)

Magnesium, nature's calcium channel blocker
 
If you have questions about other supplements, please go to the Symptoms and self-care forum and use search.

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Ryder   
Ryder

Thanks Alta & Asjf for responding and apologies for not getting back to you sooner.

 

You know during the 4-days when I was checking back in on this post I did some own research which included seeing other doctors and even the chemists who sell this crap. The majority was of the opinion that it wouldn't help. Exactly what my original GP had suggested but my father was super keen on this person as Mr Fixit.

 

What the chemists and other doctors said when I asked them about the interaction of an anti-depressant Zoloft with these supplements:

  • - Acel-L-Carneteine should not be taken in conjunction with an anti-depressant as it will stimulate your mind.
  • - Depends what brand you take and absorbtion for the body. 10 different fricken brands for the 1 supplement and in capsules.
  • - A different doctor said they will have NO effect and suggested I just pursue meditation, yoga and excercise and really come off the medication really slowly.
  • We had a documentary come out in Australia on the ABC recently called 'Swallowing it' on the programme Four Corners. It mentioned the un-benefitial affects of CoQ10 studied by a group of students at Monash Uni in Melb.

What has happened until now:

 

I had stopped taking them as Alta suggested and on my GP's advice. I then kept going on a week and back a week which I felt really bad about because I kept getting chronic nervous and muscle pains. I thought this may be from withdrawing to fast.

 

After a while I stopped for a month, saw a nutritionist who just gave me a loaf of bread to start off in the morning and while it didn't fix things. I felt a whole lot better. It's along the lines of the SCD diet that was advocated on Elaine Gotschalls book. I believe most of these things can be found through diet.

 

Yesterday: I was again suffering a usual copybook bout of withdrawal pain and I did use some CoQ10 and L-Carneteine felt like shite. I swear before I heard of such a thing called supplements, now I am walking backwards. The only positive being that I remember a worse time in my life so I know that I'll get through this, albeit in time.

 

To answer your q's:

 

I am interested in getting off sertraline and I have read your guides to getting off it at length. When I stopped first time overseas, I felt brilliant. Albeit for a month or two so I know that whilst I do need them, I know that I can do without them. That was the good part of going CT. So for the meantime, I am thinking of going back to my original dose of 200mg to stablize and like everyone else who has gotten through it, get off this boat last.

 

Ryder.


 

 

 

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scallywag   
scallywag

Ryder -- please do not return to 200 mg in a single updose. The drug changes, dose changes and cold turkey may have sensitized your CNS (central nervous system) for the near future.

 

If you still feel the need to increase dose, would you be willing to try "sneaking up" on a dose that works by increasing by 10 - 25 mg?  You could hold that dose for 3-4 weeks to see what improvement if any you notice. Making your increase gradual will likely allow you to stabilize at a lower dose, thereby shortening any eventual taper in the future.

Edited by scallywag

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Ryder   
Ryder
On 6/26/2017 at 1:09 AM, scallywag said:

Ryder -- please do not return to 200 mg in a single updose. The drug changes, dose changes and cold turkey may have sensitized your CNS (central nervous system) for the near future.

 

If you still feel the need to increase dose, would you be willing to try "sneaking up" on a dose that works by increasing by 10 - 25 mg?  You could hold that dose for 3-4 weeks to see what improvement if any you notice. Making your increase gradual will likely allow you to stabilize at a lower dose, thereby shortening any eventual taper in the future.

 

Hi Scallywag,

 

Thanks for your response to my original post. I am still on 100mg of Zoloft daytime. Still thinking of going back to 200mg. Is there a reason you suggested to increase slowly back up to 10-25mg. Did you have a similar experience?

 

Would really appreciate your immediate response and apologies for not replying to you sooner,

Dave.

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scallywag   
scallywag

Ryder, when you started taking sertraline your CNS (central nervous system) made changes to adapt to the presence of the drug. When you went cold turkey (200 mg to 0 mg overnight), your CNS had to make a HUGE number of adjustments.  Many of those adjustments show up as what we call withdrawal symptoms.  You've been taking 100 mg for several months now (since May or June, your signature isn't clear about when you reinstated), your CNS has likely made more changes. As I wrote, it's better to "sneak" up or down on doses rather than make dramatic changes. The greater the change, the greater the risk of symptoms.

 

I have not personally made such a dramatic dose change but have seen others do so to varying effect. There's a reasonable risk that jumping back up to 200 mg all at once may trigger more and/or worse symptoms.

 

Here are a few links that describe this process in helpful ways:

How your brain responds to psychiatric drugs - aka "Brain remodeling"

Youtube video, 4 minutes: Healing from antidepressants

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Ryder   
Ryder
1 hour ago, scallywag said:

Ryder, when you started taking sertraline your CNS (central nervous system) made changes to adapt to the presence of the drug. When you went cold turkey (200 mg to 0 mg overnight), your CNS had to make a HUGE number of adjustments.  Many of those adjustments show up as what we call withdrawal symptoms.  You've been taking 100 mg for several months now (since May or June, your signature isn't clear about when you reinstated), your CNS has likely made more changes. As I wrote, it's better to "sneak" up or down on doses rather than make dramatic changes. The greater the change, the greater the risk of symptoms.

 

I have not personally made such a dramatic dose change but have seen others do so to varying effect. There's a reasonable risk that jumping back up to 200 mg all at once may trigger more and/or worse symptoms.

 

Here are a few links that describe this process in helpful ways:

How your brain responds to psychiatric drugs - aka "Brain remodeling"

Youtube video, 4 minutes: Healing from antidepressants

 

You are correct. I re-instated 100mg permanantly. I came back from overseas from in June 2016. And re-instated from about December 2016.

 

During the time between coming back and re-instating to 100mg (from June 2016 - Dec 2016) i was gradually tuning up from 0.25 mg to .5mg as I felt the effects of Sert to strong in public spaces.

 

I have been told by my Pyschiastrist to re-instate 200mg. When i go to 150mg I find it not tolerable where there is emotional, mental, pain. Most of this I believe may have been caused by taking supplements (CoQ10, L-Carniteine, NAC) instead of my medicine, as a Naturopath explained that Sertraline was designed only for a short use of time in the 70's and explained that I didn't have an option.

 

I know that jumping between doses or taking them inconsistently is wrong. That is key from what I''ve learnt from the forums on SA. I previously just thought it to be heresay and am stricter about missing a dose of 100mg.

 

Thank you for the links you have provided, particularly the second one. I am seeing my GP today as I still am just not at all coping on Sertraline. So SA recommends slow slow slow which is how the brain operates. In your experience s ok to go back on Sertraline if my Doc suggests this? I was hoping she'd get me onto a new family of SSRI's and forge a new path as I feel I have built a certain tolerance to the drug.

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Ryder   
Ryder

Hi all,

 

I have read the topic >

 

However still I am confused.

Currently taking an SSRI in Zoloft 100mg and Clonazepam (Benzo) 4mg day-time.

In this instance do I taper off the accelerator (Zoloft) or break (Clonazepam) first ? I have CT'd once before and it might seem light a stupid question. But I don't want to get this wrong as the naturopath that I visited suggested that I taper my Clonazepam down from 4-2mg first. :excl:

 

Sincerely,

Ryder.

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ChessieCat   
ChessieCat

There is a short explanation here http://survivingantidepressants.org/topic/300-important-topics-in-the-tapering-forum-and-faq/ which might help:

 

Taking multiple psych drugs? Which drug to taper first?
If you're not having an adverse reaction from the other medications, taper the most activating drug first. This is usually an antidepressant or stimulant (ADHD drug).

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Ryder   
Ryder

Thanks ChessieCat.

 

I think you are bang on right about this. I am going back to my Doc this so someone can watch over what I'm doing regardless if I I'm right or wrong and want to get off this drug!

But my general feeling is, it is the SSRII giving me Pelters.

 

Your answer is actually just basic common sense. But my goodness do I need it as I just can't think clearly atm.

I'm hanging in there. With one step forward at a time.

 

Thanks for your no-nonsense reply :).

 

Dave.

 

 

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