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Ttgreat54

Ttgreat54: Switch from Pristiq to Effexor

29 posts in this topic

Posted (edited)

Great Post, Thank You ! ["How I am coping with depression" by apathetic]

Very informed, you know your stuff.

I'm new to all of it, but an advid researcher, also very in tune with My body, So I knew all of this....

What I do not Know is,

Should I be going from Prestiq 100mg to Effexor as of this past Wk.

7 days 50 mg Prestiq, w/ 37.5 mg Effex.

Now, Prestiq every other day for 3 days, Then Stop .Then adding another 37.5 Effex, Not there yet, a few more days.

 

I Am Petrified of Effexor Now !!!

After Reading these boards.

I had a Very Tragic Event, You wouldn't believe if I told you. 

Lawyers, traveling back & forth from West coast to East Coast, for the past 20 mons, hardly home,  because of the Fight to save someone's life.

So clearly Stress off the charts, PTSD

Intensive out patient therapy....

My WD so far, Extreme OCD, Hyper as Hell, Can't eat, Haven't Slept in 22 mons, since....

Prestiq is a Nightmare HELL to get off of. I did it once, 4 yrs ago, then had to reinstate after a month. Plus I didn't it myself, Stupid, Cut them in half, Even More Stupid, which caused them to release at triple the forces, causing that extreme Anxiety, I never have suffered with Period, just as a WD symptoms. 

So Any help would be greatly appreciated. I'm SCARED Now...

I pray I haven't Already done damage by taking this Effexor in the last 8 days.

That's how powerful a drug it apparently is. This I did not know...To Messed up to look into it myself, Not my usual MO, but I'm So out of it, just Not Myself !!

I hear Myself Rambling on, instantly Grab My Mouth, to Shut it UP. I KNOW, I'm Acting Like a FREAK 

Thanx so much 4 your post

Edited by scallywag
added link to mentioned post; split post from original location

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Ttgreat, -- Welcome to Surviving Antidepressants (SA)

 

As I wrote in the topic where you originally posted (link to that topic), I've moved your reply to your own introduction topic. This is YOUR introduction topic -- the place for you to ask questions, record symptoms, share your progress, and connect with other members of the SA community.

 

You will need to follow this topic, i.e. select "Notify me of replies" when you post here, so that you get notified when another site member posts here.

 

Your symptoms are withdrawal symptoms, from the decrease and then discontinuation of Pristiq, not from the Effexor.

 

A couple of things:

  1. Decreasing by 50% is a HUGE reduction in dose. We suggest decreases of no more than 10% to minimize withdrawal symptoms.
     
  2. Waiting only a week after a decrease is far too short for many people. We suggest holding for at least one month after a decrease, even a small decrease (< 10%).

Please read this topic to understand more about our philosophy: Why taper by 10% of my dosage?.

 

We have a member who switched from Pristiq to Effexor and found that her switch from 50 mg Pristiq to 75 mg Effexor didn't feel quite right. She and a moderator both think that taking double the number of mg of Effexor that one took as Pristiq might have made her switch easier.  You can read her story at this link: baroquep: Pristiq taper help -- advice needed.

 

Your doctor is mis-under-educated about the effect of these medications and the risks of such a dramatic "taper" plan.  Your doctor's plan is like telling you to jump off a cliff, without safety cables or training. Decreasing by 10% (or less) is like walking a couple miles along the the road to the stairs carved into the cliff and slowly making your way down the stairs, holding on to the railings on both sides.  Either way you get to the water or the bottom of the canyon, but one way is a lot less risky than the other.

 

How do you feel about telling your doctor about your symptoms and asking for a prescription for an increased dose of Effexor, at least 150 mg?

 

When you start taking a psychoactive medication such as Pristiq or Effexor, your CNS (central nervous system) makes changes to itself -- making some neurotransmitter (e.g. serotonin) cells less sensitive and/or shutting them down.  When you decrease the dose or discontinue the drug, the CNS has to undo all the changes it made over the years that you were on the drug. It is best to taper slowly to give your CNS the time it needs to do this work. For other descriptions and explanations, check out these links:

How your brain responds to psychiatric drugs - aka "Brain remodeling"

Youtube video, 4 minutes: Healing from antidepressants

 

A request: Would you summarize your history in a signature -- drugs, doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly?

  • Any drugs prior to 24 months ago can just be listed with start and stop years.
  • Please use actual dates or approximate dates (mid-June, Late October) rather than relative time frames (last week, 3 months ago)
  • Spell out months, e.g. "October" or "Oct."; 9/1/2016 can be interpreted as Jan. 9, 2016 or Sept. 1, 2016.
  • Please leave out symptoms and diagnoses.
  • A list is easier to understand than one or multiple paragraphs.
  • Link to Account Settings – Create or Edit a signature.

This is YOUR introduction topic -- the place for you to ask questions, record symptoms, share your progress, and connect with other members of the SA community. I hope you'll find the information in the SA forums helpful for your situation. I'm sorry that you are in the position that you need the information, but am glad that you found us.

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TY, Scallywag & Chessiecat,

Im really out of it, Cant think,  i STOPPED the Effexor, now taking the Prestiq 50 mg, every other day. From 100 mg.

 

I think this is Way too much of a Drop.

My dr. Wants me to Stop it Next Wk & Start over Fresh, she Said,

I was Like What ?????

Ya, she very sweet & compassionate, 

But i don't think she Gets the science behind any of this. Nor gone through it herself. 

 

PS, i Still Want My Profile Name Changed, i sent a letter, but No response, along with new name.

I Will do the signature thing, when i can Think to figure it OUT!!

 

Feeling like im Buzzing everywhere,

My Symptoms are off the charts...

Thought i was having a heart attack the other night !!

Everyday its different 

Prestiq Only comes 50 mg, Lowest.

Ty both so much

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I Apologize, 

 

Ive Just Never in My Life Felt

So Much body Over-stimulation With

Brain Fog at the same time !!

 

Your site, signature, all seems confusing, im Usually Sharp

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Ty, Also Scallywag

 

Your symptoms are withdrawal symptoms, from the decrease and then discontinuation of Pristiq,not from the Effexor.

 

Ok, I Get 1/2  this Statement  ??

 

Are You saying,

Effexor 8 days 37.5 mg

Then STOP

Effexor, is Out of My System  ??

 

No Lasting Effects ???

 

This is ALL Prestiq ?? Im still on 50mg

I know its too Fast of a decrease, 

But w/ No lower dose than 50 mg,

What are my options....

I havent read anything yet...

My brain cant hardly concentrate enough to write this...So Shaky

TY

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Hi Ttgreat54, Sorry to hear you are having such difficulty.  Unfortunately far too many doctors do not have experience tapering people safely off of these drugs and often try to take people off too quickly which results in horrendous withdrawal symptoms.  It is never recommended to alternate doses of these drugs, it is like playing ping pong with your brain when you go up and down in dosage.  The brain craves consistency and you should be taking the same dose every day.

 

Pristiq and Effexor are basically the same drug, although Pristiq is a concentrated version of Effexor, in other words Pristiq is stronger, and both drugs are difficult to withdrawal from.  I think because you switched out 50mg of Pristiq for 37.5mg of Effexor is the reason you are having such difficultly (as well as the 50% reduction of Pristiq). The doctor should have switched you out to a much higher dose of Effexor to compensate for the 50mg of Pristiq ... 50mg of Pristiq is likely equivalent to 100mg of Effexor.  My doctor switched me out at 50mg Pristiq for 75mg Effexor and it wasn't enough to compensate due to Pristiq being a lot stronger.  While switching from Pristiq to Effexor is doable, I don't think your doctor took the best approach and while I understand her/his rationale, it unfortunately didn't have positive results.  In any event, what is done is done and it is best to focus now on what you need to do to get you stabilized.

I am not a moderator and can only guide you based on my own experience, so I strongly encourage you to deal directly with a moderator to get you back on track.    From your posts, it's not clear how long you have been at 50mg Pristiq so the moderators will need to know this.  Often reinstating a small amount of the original drug is enough to get back on track but without clear dates and when you started and stopped Effexor it will be difficult for them to put a plan in place.  Please put together a post listing dates started/stopped, dosage, drug names, etc. so that a moderator will know what they are dealing with.

 

There are a few people on this site who are tapering directly from Pristiq by having it compounded (ChessieCat is one of them) and seem to do okay.  If I had to do it all over again, I would have probably had Pristiq compounded by a pharmacist (with a time release mechanism added) rather than switch to Effexor as switching between drugs adds yet another layer of difficulty in an already difficult situation.  

Wishing you all the best and hoping that you find things settle down for you soon. 

 

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Ttgreat54 -- If you've switched back to Pristiq at 50 mg, please take it EVERY day at approximately the same time each day. Skipping days is a guaranteed recipe to further destabilize you, worsening current symptoms and creating new ones.

 

Are you willing to be patient as your CNS (central nervous system) deals with the medication changes and then eventually settles down? You will have symptoms for a while as your CNS adjusts, then they will diminish over time.  You need to be patient -- this means not looking to the prescription bottle to fix your symptoms. The only thing that is likely "fix" your symptoms is stable dosing + time.

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Thank you so much 4 your reply

Scallywag & baroquep,

Ok Scallywag, 

That makes Sense. 

I will take the 50 mg Prestiq EVERY Day,

to destabilize. Even tho its a long Drop from 100mg.

How long, do you foresee this taking, Approximately???

Also Scallywag, 

What would be my Next Step !!!????

Do i add something else, or stop ?

I don't see how i COULD STOP,

With 50mg being the lowest Prestiq goes ??

I trust you more than my dr. That's pretty Sad.

 

But experience is the Best experience in judging Lifes Trials

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Sorry, i Meant, 

To Stabilize  !!

TY both

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Posted (edited)

Taper - PRESTIQ 

(7 yrs. @ 50 mg) to

100 mg past (8 Mons)

Due to Tragic Events

Back to....

50mg Prestiq this past 2 weeks.

 

Dr. Advised - Taper 50 mg PRESTIQ 

Every other day, 

For 3 Doses...

Then Every 3rd Day😲

Then STOP

WHAT ???!!!

 

I Cant, Its Impossible,  My CNS OFF THE CHARTS.

Wrote Dr. An Email, Stating 

Im taking 50 mg Everyday Now,

To Desperately TRY & Stabalize !!

 

Ive Now Asked 4 My Valuim BACK,

that they took from Me last month,

Without Tapering Me.....omg,

Luckily I Didnt Need it, Wasnt Taking It,

Because i Didnt Feel it was doing a damn thing for Me. 

So No Problems there.  T.G.

But I Most Definitely have PTSD after Seeing My Son Kill a Pedophile Right in Front of Me.

Will the Valium Help Me with My SEVER 

W/D ??

TYSM

 

Edited by scallywag
merged topics

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6 hours ago, scallywag said:

Ttgreat54 -- If you've switched back to Pristiq at 50 mg, please take it EVERY day at approximately the same time each day. Skipping days is a guaranteed recipe to further destabilize you, worsening current symptoms and creating new ones.

 

Are you willing to be patient as your CNS (central nervous system) deals with the medication changes and then eventually settles down? You will have symptoms for a while as your CNS adjusts, then they will diminish over time.  You need to be patient -- this means not looking to the prescription bottle to fix your symptoms. The only thing that is likely "fix" your symptoms is stable dosing + time.

TY Scallywag, 

Yesterday & today & from here forward,

I will take 50mg daily to STABILIZE. 

How Much Time do u think it should take ???

I Will be Patient, Keep all this in

Perspective & Not Allow anyone Try

To Change My diagnosis, based on my

W/D Symptoms !!

 

You are All RockStars, 

 

I apologize if im doing any of this Wrong

I.e. posting Wrong stuff in wrong areas.

Im sure ill get the hang of it.

TY

Very Grateful 

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I don't know how long it will take you to stabilize. You've been through some dramatic changes in dose and medication. Think about this in terms of many weeks instead of an expectation of a few days. Here's a relevant discussion on the topic:

How long to stabilize after reinstating or updosing.

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You started a in a new topic, "Im in Hell," in the Symptoms forum. I've moved your post to your introduction topic so that all your information, questions and answers are in one place. This forum works differently than other web communities.  We want to have all your information together in one topic so that we don't have to search the entire site to find details of your situation to answer your questions.

 

 

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20 hours ago, scallywag said:

You started a in a new topic, "Im in Hell," in the Symptoms forum. I've moved your post to your introduction topic so that all your information, questions and answers are in one place. This forum works differently than other web communities.  We want to have all your information together in one topic so that we don't have to search the entire site to find details of your situation to answer your questions.

 

 

Ok Scallywag, 

 

Thank You.

So I Should from now on, just be posting Everything in this area or post ?

Sorry, obviously feel like ****, Shaky & 

Trouble concentrating. 

I will read the link & try to think in terms of weeks, not days.

Im going to have to Travel again soon to be with my Son who is sick & stuck in MI, We are from CA.

This has Me Very Worried, Feeling this Way, but Iam my Son Advocate & cannot abandon him, ever !!!

 

So thePressure Is ON for ME to Feel BETTER FAST !!

Ty again

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Please post questions about your situation here in your introduction topic. It's the first place moderators and most members look.

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UPDATE

After a Week of dropping my Prestiq 

100 mg to 50 mg, has Clearly sent my CNS into Shock !!

These W/D's are Much to hard on my body. I know in TIME this will subside, at Least I Pray they do !!

 

But for Now, its too Much, I have been House Ridden for 2 wks Straight !!

 

I do Not even Feel Safe Driving My Own Vehicle!! Thats how SHOT My Nevers Are !! 

 

So Yestetday I wrote my Psych.Dr. & told her, I WANT My Valium back, until i feel Stable.Then Stop again.

 

I was put of this drug, during the last yr, because of family Tragedy, but it wasnt helping, so I Stopped taking it. 

 

NOW its Like a WONDER DRUG..

Omg, What a Difference, A 50% Difference, to manage, until I become Stable. Possibly a few more Wks. One Can Hope !!

Then I will Stop the Valium again. 

 

This is My Update.

 

Thanx 4 all your help

 

Hope I posted correctly this time.

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On 8/7/2017 at 8:26 AM, baroquep said:

Hi Ttgreat54, Sorry to hear you are having such difficulty.  Unfortunately far too many doctors do not have experience tapering people safely off of these drugs and often try to take people off too quickly which results in horrendous withdrawal symptoms.  It is never recommended to alternate doses of these drugs, it is like playing ping pong with your brain when you go up and down in dosage.  The brain craves consistency and you should be taking the same dose every day.

 

Pristiq and Effexor are basically the same drug, although Pristiq is a concentrated version of Effexor, in other words Pristiq is stronger, and both drugs are difficult to withdrawal from.  I think because you switched out 50mg of Pristiq for 37.5mg of Effexor is the reason you are having such difficultly (as well as the 50% reduction of Pristiq). The doctor should have switched you out to a much higher dose of Effexor to compensate for the 50mg of Pristiq ... 50mg of Pristiq is likely equivalent to 100mg of Effexor.  My doctor switched me out at 50mg Pristiq for 75mg Effexor and it wasn't enough to compensate due to Pristiq being a lot stronger.  While switching from Pristiq to Effexor is doable, I don't think your doctor took the best approach and while I understand her/his rationale, it unfortunately didn't have positive results.  In any event, what is done is done and it is best to focus now on what you need to do to get you stabilized.

I am not a moderator and can only guide you based on my own experience, so I strongly encourage you to deal directly with a moderator to get you back on track.    From your posts, it's not clear how long you have been at 50mg Pristiq so the moderators will need to know this.  Often reinstating a small amount of the original drug is enough to get back on track but without clear dates and when you started and stopped Effexor it will be difficult for them to put a plan in place.  Please put together a post listing dates started/stopped, dosage, drug names, etc. so that a moderator will know what they are dealing with.

 

There are a few people on this site who are tapering directly from Pristiq by having it compounded (ChessieCat is one of them) and seem to do okay.  If I had to do it all over again, I would have probably had Pristiq compounded by a pharmacist (with a time release mechanism added) rather than switch to Effexor as switching between drugs adds yet another layer of difficulty in an already difficult situation.  

Wishing you all the best and hoping that you find things settle down for you soon. 

 

Hi Baroquep, 

Your Quote :

I would have probably had Pristiq compounded by a pharmacist (with a time release mechanism added) 

-------------------------------------------------------

Could you explain what you meant by having my pharmacist Compound Prestiq for me ???

 

Are you saying, have him make a liquid form of it, so i can eventually taper at Much smaller doses ??

 

Or am i Way Off...

Im not following that.

 

Thank you,  your help is greatly

Appreciated !!

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I have my Pristiq compounded.  They crush up the tablets and measure out the powder into capsules.  I tell them what doses I want them to make the capsules.  The link to my topic is in my signature.  Fresh is another member who has had hers compounded.

 

Here is the SA discussion:  compounding-pharmacies-us-uk-and-elsewhere

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17 hours ago, ChessieCat said:

I have my Pristiq compounded.  They crush up the tablets and measure out the powder into capsules.  I tell them what doses I want them to make the capsules.  The link to my topic is in my signature.  Fresh is another member who has had hers compounded.

 

Here is the SA discussion:  compounding-pharmacies-us-uk-and-elsewhere

TY Chessie,

 

I was told my 50 mg Prestiq tablets are extended relief, and crushing them forces them to go at Triple the Force all at once into your system, causing Worse Side effects.

They are Square Orange tablets 

Defalaxine or something like that. 

Is this the same med you were/are on.

Ill read what you sent me.

TYSM

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Yes, I am on the same type of tablets of Pristiq.  I have been using the compounded capsules since November 2016 and haven't had any issues.  I also take magnesium.  I have found that if I don't take it I feel a bit of anxiety.  When I do take the magnesium have found that it takes the edge off the anxiety.  I haved started and stopped it several times and have experienced the same thing each time.

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24 minutes ago, ChessieCat said:

Yes, I am on the same type of tablets of Pristiq.  I have been using the compounded capsules since November 2016 and haven't had any issues.  I also take magnesium.  I have found that if I don't take it I feel a bit of anxiety.  When I do take the magnesium have found that it takes the edge off the anxiety.  I haved started and stopped it several times and have experienced the same thing each time.

Ok Wow, TY Chessie,

Great Info there, ill start the Magnesium straight away !!

I was given a list of pharmacies that compound meds. On here.... However, I've checked them All and None of them compound Prestiq !!!

I did write a letter to a few of these pharmacies to see if they can !

Can you tell me what pharmacy you use, i dont care what it Cost.

Money is not a Problem. My health & well being is, however. 

Btw, I  told my dr. To give me Valium, temporarily, and its Completely working, like 50%, which is Much more tolerant on my body.

When I've stabilized I will Stop the Valium, as I won't have any Need for it.

Its Not my thing at All !!!

Im guessing only a few weeks, as im already, a few weeks in, on 50mg from 100mg. 

Ty Chessie, you've been a huge help.

Actually Everyone Here, has been.

I am So Grateful to have find this site.

I can type & think much better.

Wow NEVER SNRI AGAIN !!!!

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http://survivingantidepressants.org/profile/7196-scallywag/

 

A request: Would you summarize your history in a signature -- drugs, doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly?

 

  • Any drugs prior to 24 months ago can just be listed with start and stop years. 
  • Please use actual dates or approximate dates (mid-June, Late October) rather than relative time frames (last week, 3 months ago) 
  • Spell out months, e.g. "October" or "Oct."; 9/1/2016 can be interpreted as Jan. 9, 2016 or Sept. 1, 2016. 
  • Please leave out symptoms and diagnoses. 
  • A list is easier to understand than one or multiple paragraphs. 
  • Link to Account Settings – Create or Edit a signature.

 

OK Scallywag, 

Im going to Attempt to do my 

Signature Now !! 

TY 4 ALL the information You have given Me, You have been a TREMENDOUS HELP !!

I hope I do this Right, as I am Still in a Serious Brain Fog, State of Mind.

I know YOU said My Body NEEDS TIME⏰ to Heal, " Dont REACH 4 the Bottle ".

 

But the 0.5 Valium, has Helped Me More than I can Say. 4 Me, its TEMPORARILY. NOT LOOKING to Switch 1 habit 4 Another !!!

Thanx Again

:)

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Ttgreat54,

You need to be very careful with valium or any other type of benzo (tranquilizer), as they are highly addictive.  It is my understanding that it only takes three weeks to become addicted to benzos and they are a lot more difficult to get off of than anti-depressants.  They will also likely further destabilize your already fragile central nervous system.  ChessieCat warned me when I first started to taper to try to manage my symptoms without taking a tranquilizer.  I ran into trouble a couple of times during my taper and looking back, I am so very thankful that I was warned not to start taking Ativan (another benzo).  It is too easy to start relying on tranquilizers to get some relief from withdrawal and then you end up getting addicted to that drug as well.  Withdrawal does settle by itself if you allow it to.  My withdrawal symptoms did settle down without the addition of another highly addictive drug but it took time.  If I were you, I'd let my central nervous system settle down on Pristiq for a very long while, at least a few months or longer.     

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baroquep is almost right with the benzos.  I've heard that you can become dependent in as little as 2 weeks.

 

As far as compounding Pristiq, I am in Australia.

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Posted (edited)

On 2017-08-10 at 9:09 PM, scallywag said:

Have you read this topic?

Or watched the video in the first post?

Simplest way to make a liquid is to use the same number of ml as your capsule or tablet.

 

50 mg tablet? Use 50 ml water.

20 mg tablet? Use 20 ml water

75 mg capsule? Use 75 ml water.

Scallywag, 

 

Thanx 4 this info.

Does this apply to Prestiq ? I was told it is an extended relief tablet ??

Does doing this cause to be Released more rapidly all at once ? Or Not

 

Thank you

Edited by scallywag
split from topic: making a liquid from Celexa

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Posted (edited)

On 2017-08-10 at 7:40 PM, baroquep said:

Ttgreat54,

You need to be very careful with valium or any other type of benzo (tranquilizer), as they are highly addictive.  It is my understanding that it only takes three weeks to become addicted to benzos and they are a lot more difficult to get off of than anti-depressants.  They will also likely further destabilize your already fragile central nervous system.  ChessieCat warned me when I first started to taper to try to manage my symptoms without taking a tranquilizer.  I ran into trouble a couple of times during my taper and looking back, I am so very thankful that I was warned not to start taking Ativan (another benzo).  It is too easy to start relying on tranquilizers to get some relief from withdrawal and then you end up getting addicted to that drug as well.  Withdrawal does settle by itself if you allow it to.  My withdrawal symptoms did settle down without the addition of another highly addictive drug but it took time.  If I were you, I'd let my central nervous system settle down on Pristiq for a very long while, at least a few months or longer.     

Hi, TY Baro,

Yes, if i had not already been on this drug a month prior, because of the PTSD i suffered, seeing My son AX another human being in the head, because he was a Pedophile,  than i wouldnt have tried it to begin with. My Drs had toTalk me into taking this drug !!

I really didnt expect it too work, as it Never worked Last time, at 0.5 mg

Which is Why I Stopped taking it after 6 mons, Cold Turkey. Without one Side effect.

Im Not one to Use Drugs Period in my life. Ive never found them fun Nor Recreational. 

So Im Not Worried.

However ive taken the advice from these boards and Order a Great Magnesium L theronate, (spelling) sorry.

Also, as Soon as I dont Need the Valium I have No intention of taking it.

My dr. Knows I took myself off of it B4, and probably the reason she gave back at my request. 

She may be uneducated, but she is Listening to me, ill give her that.

She even asked the pharmacist 4 me if she could coumpound my Prestiq. 

At My Request.

That was pretty Cool, in my book.

 

Unfortunately the Pharmacist told her it wasnt safe for the patient. 

That i disagree with.

Edited by scallywag
mistake - added note to wrong post

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Valium:  Just because you were able to stop it cold turkey previously doesn't mean that you will be able to do the same thing next time.  Please consider doing a taper of valium, even if you do it faster than 10%.  You will be doing your brain and CNS a big favour.

 

Pristiq:  There are many compounding pharmacies.  I suggest you find another one.  You can use this locator:  http://www.pccarx.com/contact-us/find-a-compounder

 

You could give your doctor my website which has my brief history (NB: it's not searchable in google):  http://adwithdrawal.weebly.com/

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6 hours ago, Ttgreat54 said:

Does this [making a liquid] apply to Prestiq ? I was told it is an extended relief tablet ??

Does doing this cause to be Released more rapidly all at once ? Or Not

 

Ttg: Extended release tablets do not do well when dissolved, losing their extended release characteristics. 

 

Please read the first post in Tips for tapering off Pristiq (desvenlafaxine)

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