• Announcements

Altostrata

Tips for tapering off Effexor and Effexor XR (venlafaxine)

192 posts in this topic

Thank you Alto

 

It's amazing how you help everyone here.

Share this post


Link to post
Share on other sites

Ahhh....sometimes I'm stretched pretty thin!

Share this post


Link to post
Share on other sites

I came across a study between the difference between venlafaxine generic ton brand Effexor XR. I am think of switching from immediate to xr.

 

http://www.imacynic.com/596

 

Has anyone changed from generic immediate release to effexor XR?

Share this post


Link to post
Share on other sites

Some people are sensitive to differences between brands. However, Lexy, if you've been taking generic Effexor for a long time, it's unlikely that's the source of your symptoms.

 

Please answer my questions in your Intro topic so we can get to the bottom of this.

Share this post


Link to post
Share on other sites

Does anyone use their leftover beads and put them in generic gelatin capsules? I won't be doing it yet but I am keeping those leftover beads for when I'm at the end of my taper and I was thinking that I might be able to weigh them and make up my own 20/15/10 mg doses. I have seen a reference to others doing this before, I believe possibly on this site but I can't find it now. Is this safe to do?

Share this post


Link to post
Share on other sites

Yes, you can do that. In the meantime, keep them in a clean medicine bottle marked with the expiration date, dosage, and manufacturer.

Share this post


Link to post
Share on other sites

Taking 75mg XR, 1 cap/day... Attempting to titrate down by 5 beads every two weeks. Does this seem gradual enough? Thanks in advance...

Are you also struggling with the whole 10% thing too? I started my taper by just taking one bead out a day from 150 mg capsules. I'm now on 62 beads a day so I have no idea what 10% is now but I'm beginning to think that may be too much. I think i'll just try what you've said. 5 beads every two to three weeks and see how I go. I wouldn't know where to start with the 10% thing now.

Share this post


Link to post
Share on other sites

Harmonica, reducing one bead a day is too fast. 10% of 62 beads is about 6 beads -- per month. A reduction of 1 bead per week is about a 6% reduction per month (4 beads per month).

 

That's how gradual a gradual taper is.

 

RhoSee, the number of beads in a capsule varies from dosage to dosage and manufacturer to manufacturer. You need to count the number of beads in several capsules to get an estimate of how many beads there are in a capsule, on average.

Share this post


Link to post
Share on other sites

Harmonica, reducing one bead a day is too fast.

 

Yes, I think you're right. I feel rather fortunate that I have not suffered any real withdrawal thus far. When I say that I'm on 62 beads now what I mean is that is the amount I am taking out from a 150 mg capsule. I have no idea how many beads are in one of those capsules but after removing 62 beads the capsule looks to be about two thirds full. I wouldn't know how to calculate 10% from a capsule that is two thirds full. I may have to do a full bead count. Either way I will slow it right down.

Share this post


Link to post
Share on other sites

Alto, for the last 2 years of tapering, i've been doing this.  I noticed that all my 75mg pills range from 240-272 pellets.  So I took a few pills, counted the amounts for each, then took an average which was 242.  I then made sure each pill had 253 pellets, then took out my percentage of taper, then took them.  I think this is why I was never feeling right from time to time during those 2 years of tapering, and now ended up like this. I had swings in dosages of almost 30 pellets!  Am I right in this?

Share this post


Link to post
Share on other sites

It could be.

 

Many people taper Effexor XR by removing a certain number of beads from each daily dose, then taking the remainder. This causes a little variation in dosage, but it seems to work for most.

Share this post


Link to post
Share on other sites

It could be.

 

Many people taper Effexor XR by removing a certain number of beads from each daily dose, then taking the remainder. This causes a little variation in dosage, but it seems to work for most.

It must be, 30 pellets are a lot no? a 5% drop per month usually was around 4 or 5 pellets.  Add to that another 15-30 more, must be destabilizing.

Share this post


Link to post
Share on other sites

You may be very sensitive to dosage changes.

Share this post


Link to post
Share on other sites

It it better to count the beads or weigh them?

 

I took out the beads from two capsules and ea varied in amount of beads. One had 124 the other 145 beads. I also weighed the beads and were .124 and .126.

 

Which method is more precise?

 

I've heard other people say the count IN instead of counting OUT the beads?

If you count IN wouldn't it be difficult to ascertain what percentage you are taking since ea capsule has a variance in count? By counting OUT beads from a 37.5mg I would start by taking out one bead, then two, then three, etc every week.

 

I just got Effexor Xr and would like to slowly switch from immediate release to brand name.

Share this post


Link to post
Share on other sites

Lexy, please read the first post in this topic.

With Effexor XR, your only choice is to count beads. This can be an imprecise measurement that becomes a problem at very low dosages.

With regular Effexor, you can cut tablets up, make a homemade liquid, or have a pharmacy make a compounded liquid for greater precision.

You may recall I urged you not to switch to Effexor XR because tapering regular Effexor is easier in some ways.

Share this post


Link to post
Share on other sites

Yes 

I realize that the immediate effexor is easier to taper off from since you can convert it to liquid.  

Is it easier on the withdrawals too?  

I assumed because of the shorter half life on the immediate it would be even more difficult than the XR.

Share this post


Link to post
Share on other sites

One is not easier than the other, in terms of withdrawal symptoms. Liquid Effexor (from ordinary Effexor) is easier in that you can control the dosage better. If you are counting beads to taper, the smallest decrement is one bead, which may get more and more difficult as the dosage gets lower.

 

This is why one tapering option is to switch to regular Effexor late in a taper off Effexor XR.

Share this post


Link to post
Share on other sites

Lexy, I think I explained this to you before.

 

Sometimes when people have been taking the brand name for a long time, they can tell the difference if they switch to the generic. Some people can feel the difference if they switch from one generic brand to another.

 

In those cases, whatever symptoms the people had were due to manufacturing differences, not necessarily strength.

 

In your case, your initial problems had nothing to do with a brand change. You were taking the same brand all along. Now, you've made so many changes, it's impossible to tell if brand differences have any effect on you at all.

 

Since you seem to be convinced there's something fishy about your generic Effexor, why don't you take your entire dose in brand-name Effexor? At least then, you'll stop worrying about the differences between brand name and generic -- which never applied to you anyway.

Share this post


Link to post
Share on other sites

I was tld that splitting the dose taken half in the morning and half at night would be easier on the side effects. Is this true?

Share this post


Link to post
Share on other sites

Lexy if you are taking effexor XR (slow release)  you should be fine with once a day.

I take mine at the same time every day and get on ok with that. If I am late  I get a funny head

that reminds me but no real withdrawal. 

Share this post


Link to post
Share on other sites

Hello... I have been tapering for months now...after having it out with my doctor..who has no idea how to get off this ..I have followed this thread..I was on 75 mg...I taper 10 beads a week always a change on Wednesday am..I am currently taking 110 beads out with no withdrawals , thank god..since I am getting down to the nitty gritty, if withdrawals get bad I may go every 2 but as of now everything good..I have found that I am now starting to sleep pretty good as compared on full dose up all hours...can't wait to be off this fully...thanks for the help on this thread!

Share this post


Link to post
Share on other sites

You're welcome. Please note that, the lower you go, you'll need to taper by fewer beads.

We recommend a 10% taper per MONTH based on the LAST dosage. At this point, you may wish to slow down your taper -- taper by fewer beads every few weeks rather than every week. You do NOT want to trigger withdrawal symptoms!

See Why taper by 10% of my dosage?

Share this post


Link to post
Share on other sites

Hi, I have got down to 37.5mg XR tablets.  I went to my GP and asked for the capsules so I could weigh 10% reduction.  He said try the non release tablets first and cut them up.  I cut them in half and took half in the morning and half about 3pm.  I felt terrible, I couldn;t cope, felt horrendous.  I went back and asked again for the capsules.  He wrote out a prescription and I went off to the chemist to get them.  When I picked them up they were capsules with 3 mini pills inside.  I didn't want these as I wanted the capsules with the little balls inside so I could weigh them out.  I ended up having a argument at the chemist who said that is all they can get.  I went back to my doctor and he said well if that is what the chemist said that is that.  I told him that the capsules are available in 37.5mg with the small balls and he said to prescribe them he needs to know the correct name to tell the chemist.  I am confused because I thought the name was just venlafaxine 37.5mg capsules.  If I keep telling him this I will end up with the 3 mini pill ones.  I have purchased my scales the Gemini ones and when I feel strong enough I would like to try the capsules.

 

Has anyone any idea what he is talking about, I feel like I am going around in circles.  He asks for the correct name, I tell him and he says that's obviously not it.  Think I am going mad...

 

Any help please.

Poppy

Share this post


Link to post
Share on other sites

Effexor XR 37.5 (name brand) contains the tiny beads.

 

Some of the generics contain the larger tablets inside a capsule. Other generics contain beads, but I don't know what these are called or even if they're available in the UK. You'd have to talk to a pharmacist to find out which ones contain the beads.

Share this post


Link to post
Share on other sites

That's the problem I was having.  The pharmacist said he doesn't know what I am talking about.  He said the suppliers who supply the medication only have the mini pill ones.  I feel I had to find out myself, but don't know where to start.  He got quite huffy and said talk to the gp and the gp said talk to the chemist.  I am afraid that it will work out that I can't get the 37.5mg capsule and I was pinning my hopes of trying to get off this way.

 

Do you know if I can insist on having the EFFEXOR XR brand 37.5 capsules.  This is all hell.  I feel that I am trying to help myself but am going around and around.

 

Poppy

Share this post


Link to post
Share on other sites

You could ask you chemist to check the brain name and see if it is the tablets we know it isn't ...from there ...after he sees the beads tell him that is what you need in order to do a taper off the drug... 

I tried to find a  link for you about generic effexor complaints to help you in convincing him to give you brand name... 

I don't think he should have any issue giving you the brand name however you will have to pay for it... that was my experience after having issues with the generic I could get it but insurance would only cover generic so I had to pay out of pocket for it.  

peace

Share this post


Link to post
Share on other sites

I am in the UK and have Rodomel brand. Even better is the liquid.

Liquid is available here and much easier to taper. Ask your doctor to prescribe it 

because the pharmacy will not/cannot supply the capsules with beads. I would do that

because it is so much easier. Those beads are pesky little blighters that jump around

when you are counting them!  I had to insist on the liquid from my doctor but sadly had

an allergic reaction to one of the other ingredients and had to carry on with counting beads. 

 

Alternatively try another chemist, they seem to have different suppliers. 

Share this post


Link to post
Share on other sites

mammaP, do you have to take the liquid more than once a day to substitute for the extended-release drug?

Share this post


Link to post
Share on other sites

Yes Alto, mine was 2x daily. 

Share this post


Link to post
Share on other sites

I have been trying to find a capsule here in the UK of Venlafaxine that my GP will prescribe.  My question is if I can only get the capsule in 75mg (I am on 37.5mg) can I taper from this.

 

Kind regards

Share this post


Link to post
Share on other sites

Hi,

 

Yes you can do this, however since it is in a capsule form and I presume with these capsules at least in my own experience have several beads in them. Many people will taper by reducing the dosage of 75mg by eliminating beads. Since you are on 37.5mg you will have to count the beads in one capsule and then take half of them to equal your 37.5mg dose.. you can't just halve it. It must be counted (the beads) to get the correct dose...I am not aware of Venaflaxine coming in a 37.5mg dose...Once you have counted the beads and have your 37.5mg dose, you can then start eliminating beads one by one..to where you are comfortable with and then decrease in that manner at a pace you are comfortable with and with how you respond to changes.

 

There may be other posts on this subject and you may be able to view other's experience with this drug within this site..If you have never tapered before I would become comfortable with reading the possible symtoms you may endure as well as look at the various forums to educate yourself on self- care during this process and also go to www.BeyondMeds.com for more information regarding withdrawal...Wish you well on your journey to become drug free....

 

I hope this helps....

Share this post


Link to post
Share on other sites

I have been tapering vanlafaxine by counting beads from the capsule. Alternatively it is available in the UK as a liquid

which is much easier to taper. 

Share this post


Link to post
Share on other sites

poppy, the best way to go from a 37.5mg tablet to taking 37.5mg from a 75mg capsule would be to open up the 75mg capsule and weigh half the beads out -- that would be 37.5mg.

 

Otherwise, you would have to count half the beads out of every capsule. To do this, you'll have to count the beads in several 75mg capsules and figure out how many, on average, account for half.

 

That is, if you can get 75mg venlafaxine capsules filled with tiny beads. Many of the generics available in the UK seem to be filled with 3 large pellets. That will make taking 37.5mg very difficult.

 

The most accurate way to taper venlafaxine is with a liquid made from immediate-release venlafaxine, but you may have to take it 2 or 3 times a day.

 

Please read this topic from the beginning.

Share this post


Link to post
Share on other sites

Hi Abilify,

Thanks for replying.  I have been withdrawing and was taking 225mg originally and it has taken me about two years to get to this.

I will look up Beyond Meds, thanks.

 

Kind regards,

Poppy

What Alto says above is good advice...ongoing support too at the link she posted for specific needs and questions  and then this little nugget covers a lot... 

about withdrawal 

http://survivingantidepressants.org/index.php?/topic/604-important-topics-about-symptoms-including-sleep-problems/#entry5750

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now