Administrator Altostrata Posted May 23, 2011 Administrator Share Posted May 23, 2011 (edited) NOTE Also see Study finds some Cymbalta withdrawal "severe and persistant" Doctor is shocked at severe Cymbalta withdrawal symptoms Cymbalta Withdrawal Lawsuits Progressing in US Tips for tapering off Cymbalta (duloxetine) This presentation was part of the June 9, 2009 meeting minutes of the FDA Psychopharmacologic Drugs Advisory Committee meeting in Maryland. It contains many anecdotal reports of severe and long-lasting withdrawal syndrome from Cymbalta, a relatively new wonder drug.Pdf at http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/PsychopharmacologicDrugsAdvisoryCommittee/UCM172866.pdf or http://www.mediafire.com/?hfigc5c6c04ekkiAbout the FDA Psychopharmacologic Drugs Advisory Committee: http://google2.fda.gov/search?q=Psychopharmacologic+Drugs+Advisory+Committee&x=6&y=10&client=FDAgov&site=FDAgov&lr=&proxystylesheet=FDAgov&output=xml_no_dtd&getfields=*From the presentation to the FDA Much anecdotal evidence has accumulated documenting theinjury, distress and life management impacts caused bydiscontinuation of Cymbalta– The effects of discontinuation can be severe and extend for weeks oreven months Extreme mood swings (anger, irritability) Debilitating “Brain Zaps” Physical and neurological problems – Physical and psychological disturbances adversely affect job functionand family/social relationships Employment risk Negative impacts on care of family members Edited May 28, 2015 by Altostrata updated This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment Share on other sites More sharing options...
Claudius Posted May 23, 2011 Share Posted May 23, 2011 According to this article, Cymbalta is even worse than PAxil. I can hardly imagine a hell with even more scorching temperature as I went through... and that for years. Good thing that the FDA has gotten access to this report. But I have little confidence that it will lead to appropriate action. The remarks about tapering are most important, the leaflets these days do contains warnings about the need for tapering off, but none of the manufacturers delivers a working scheme in the leaflet or refers to use of the liquid... 10 mg Paxil/Seroxat since 2002 several attempts to quit since 2004 Quit c/t again Oktober 2007, in protracted w/d since then after 3.5 years slight improvement but still on the road after 6 years pretty much recovered but still some nasty residual sypmtons after 8.5 years working again on a 90% base and basically functioning normally again! Link to comment Share on other sites More sharing options...
Administrator Altostrata Posted April 20, 2012 Author Administrator Share Posted April 20, 2012 Sorry, this topic was closed by mistake. Post on! This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment Share on other sites More sharing options...
bubbles Posted April 21, 2012 Share Posted April 21, 2012 Is there a link to another version of that file? I can't open files at that site. I'd be fascinated to read the document, even though I'm not on that drug. B 2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012 January 2013 started Sertraline, over time worked up to 100mg July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg 2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg, July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg) 2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly 10% drops until 1mg, then dropped 0.1mg monthly. May 2022,0.1mg, now dropping 0.01mg per week 29 August 2022 - first day of zero! My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/21/ Current: Armour Thyroid Link to comment Share on other sites More sharing options...
Administrator Altostrata Posted April 22, 2012 Author Administrator Share Posted April 22, 2012 (edited) Put this in Google: Cymbalta (Duloxetine) Discontinuation Syndrome www.fda.gov It is the search result on www.fda.gov, a pdf download Edited February 13, 2014 by Altostrata fixed text This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment Share on other sites More sharing options...
bubbles Posted April 23, 2012 Share Posted April 23, 2012 Thanks Alto. B 2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012 January 2013 started Sertraline, over time worked up to 100mg July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg 2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg, July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg) 2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly 10% drops until 1mg, then dropped 0.1mg monthly. May 2022,0.1mg, now dropping 0.01mg per week 29 August 2022 - first day of zero! My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/21/ Current: Armour Thyroid Link to comment Share on other sites More sharing options...
Administrator Altostrata Posted February 13, 2014 Author Administrator Share Posted February 13, 2014 updated initial post. Also see http://survivingantidepressants.org/index.php?/topic/5772-prescrire-int-2013-duloxetine-withdrawal-syndromes/ This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment Share on other sites More sharing options...
Administrator Altostrata Posted March 12, 2014 Author Administrator Share Posted March 12, 2014 The FDA report about Cymbalta withdrawal is quoted here: http://www.prohealth.com/library/showarticle.cfm?libid=18811&vote=finished This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment Share on other sites More sharing options...
Recommended Posts